iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066302

Ensembl Protein ID

ENSMPUP00000000187.1

UniProt Accession

M3XM87; M3XM87_MUSPF

Genbank Protein ID

ENSMPUP00000000187

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AEYP01014364

Gene Name

ING5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000000190.1	ENSMPUT00000000191.1	ENSMPUP00000000187.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.70e-09	37.1	187	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C +
   Q: 187  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCVQ 234
           69*.*******99..*********99***********...999997.******87 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MATAMYLEHY LDSIENLPCE LQRNFQLMRE LDQRTEDKKA EIDILAAEYI STVKTLSPDQ 60
RVEHLQKIQS AYSKCKEYSD DKVQLAMQTY EMVDKHIRRL DADLARFEAD LKDKMEGSDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGACCG CCATGTACTT GGAGCACTAC CTGGACAGTA AGCACCCTTC GCGGCCCTCT 60
GGCCCGGCGC CCGCGCANNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	97.81	3.00e-112	397.00
IUUC-Atr-002906	Amborella trichopoda	33.06	2.00e-33	135.00
IUUC-Apl-003516	Anas platyrhynchos	90.69	3.00e-96	343.00
IUUC-Aca-005009	Anolis carolinensis	85.29	3.00e-107	380.00
IUUC-Ame-011879	Astyanax mexicanus	76.76	3.00e-102	364.00
IUUC-Bta-012590	Bos taurus	97.36	9.00e-116	409.00
IUUC-Bdi-014504	Brachypodium distachyon	35.39	9.00e-37	146.00
IUUC-Bra-017027	Brassica rapa	31.28	5.00e-29	120.00
IUUC-Cja-019518	Callithrix jacchus	97.92	1.00e-123	435.00
IUUC-Cfa-020620	Canis familiaris	99.17	7.00e-129	452.00
IUUC-Cpo-022085	Cavia porcellus	97.88	4.00e-119	419.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	36.36	2.00e-26	112.00
IUUC-Csa-023421	Chlorocebus sabaeus	98.33	1.00e-120	424.00
IUUC-Cin-025479	Ciona intestinalis	63.79	5.00e-78	283.00
IUUC-Csv-026288	Ciona savignyi	54.17	7.00e-74	270.00
IUUC-Dre-027588	Danio rerio	75.62	4.00e-102	363.00
IUUC-Dme-032200	Drosophila melanogaster	88.57	7.00e-40	157.00
IUUC-Eca-033493	Equus caballus	96.48	1.00e-116	412.00
IUUC-Fca-035635	Felis catus	97.27	6.00e-57	213.00
IUUC-Fal-036998	Ficedula albicollis	90.00	2.00e-110	391.00
IUUC-Gmo-039035	Gadus morhua	76.35	2.00e-98	351.00
IUUC-Gga-040578	Gallus gallus	90.42	8.00e-119	419.00
IUUC-Gac-042172	Gasterosteus aculeatus	73.86	2.00e-100	357.00
IUUC-Gma-044339	Glycine max	30.86	1.00e-32	132.00
IUUC-Hsa-045965	Homo sapiens	98.33	1.00e-120	424.00
IUUC-Kpa-049229	Komagataella pastoris	58.33	3.00e-16	78.20
IUUC-Lpe-050822	Leersia perrieri	36.48	5.00e-37	147.00
IUUC-Loc-052725	Lepisosteus oculatus	82.92	7.00e-101	359.00
IUUC-Mcc-055455	Macaca mulatta	97.38	2.00e-112	398.00
IUUC-Mtr-058089	Medicago truncatula	32.92	8.00e-36	143.00
IUUC-Mga-059312	Meleagris gallopavo	89.11	2.00e-95	341.00
IUUC-Mmr-061351	Microcebus murinus	97.36	2.00e-111	394.00
IUUC-Mdo-062282	Monodelphis domestica	95.83	3.00e-117	414.00
IUUC-Mmu-063201	Mus musculus	94.58	5.00e-120	423.00
IUUC-Mac-064625	Musa acuminata	34.29	6.00e-37	147.00
IUUC-Mlu-068192	Myotis lucifugus	97.92	5.00e-122	429.00
IUUC-Ont-072055	Oreochromis niloticus	76.67	8.00e-98	349.00
IUUC-Oan-073652	Ornithorhynchus anatinus	95.18	6.00e-113	399.00
IUUC-Ocu-073871	Oryctolagus cuniculus	96.27	7.00e-122	429.00
IUUC-Obr-076266	Oryza brachyantha	35.08	3.00e-36	145.00
IUUC-Ogl-077118	Oryza glaberrima	34.78	2.00e-34	139.00
IUUC-Oin-079049	Oryza indica	34.52	1.00e-34	139.00
IUUC-Ome-081291	Oryza meridionalis	35.60	6.00e-35	140.00
IUUC-Oni-082218	Oryza nivara	34.52	1.00e-34	139.00
IUUC-Opu-084171	Oryza punctata	35.12	7.00e-34	137.00
IUUC-Osa-085563	Oryza sativa	35.60	6.00e-35	140.00
IUUC-Ola-087103	Oryzias latipes	76.03	1.00e-94	338.00
IUUC-Oga-088066	Otolemur garnettii	87.35	5.00e-103	366.00
IUUC-Ptr-091665	Pan troglodytes	98.33	1.00e-120	424.00
IUUC-Pan-091875	Papio anubis	98.33	1.00e-120	424.00
IUUC-Psi-093904	Pelodiscus sinensis	92.96	2.00e-101	361.00
IUUC-Ppa-096009	Physcomitrella patens	33.20	9.00e-31	126.00
IUUC-Pfo-096981	Poecilia formosa	76.35	9.00e-98	349.00
IUUC-Ppe-101441	Prunus persica	34.01	7.00e-35	140.00
IUUC-Pva-102282	Pteropus vampyrus	90.83	2.00e-122	431.00
IUUC-Rno-105646	Rattus norvegicus	94.17	2.00e-119	421.00
IUUC-Sha-107031	Sarcophilus harrisii	94.35	3.00e-109	387.00
IUUC-Smo-109441	Selaginella moellendorffii	35.77	1.00e-41	162.00
IUUC-Sit-109827	Setaria italica	34.27	1.00e-34	139.00
IUUC-Sly-111750	Solanum lycopersicum	35.06	2.00e-33	135.00
IUUC-Stu-112250	Solanum tuberosum	35.06	2.00e-33	135.00
IUUC-Sbi-114826	Sorghum bicolor	34.98	1.00e-35	142.00
IUUC-Sre-115124	Sporisorium reilianum	58.21	7.00e-21	95.90
IUUC-Tgu-116837	Taeniopygia guttata	89.18	4.00e-110	390.00
IUUC-Tru-117974	Takifugu rubripes	74.79	2.00e-93	335.00
IUUC-Tni-120024	Tetraodon nigroviridis	75.10	5.00e-87	313.00
IUUC-Tae-123043	Triticum aestivum	34.25	2.00e-36	145.00
IUUC-Vvi-131487	Vitis vinifera	34.73	2.00e-33	135.00
IUUC-Xtr-132189	Xenopus tropicalis	84.10	3.00e-109	387.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence