iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092837

Ensembl Protein ID

ENSPANP00000015836.1

UniProt Accession

A0A096NS16; A0A096NS16_PAPAN

Genbank Protein ID

ENSPANP00000015836

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AHZZ01055167

Gene Name

ING4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000008024.1	ENSPANT00000001091.1	ENSPANP00000015836.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.30e-10	39.0	196	243

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 196  TYC-LCHQVSYGE--MIGCDNpdCSiEWFHFACVGLT---TKPRGK-WFCPRCSQ 243
           69*.*******99..********999***********...899996.******97 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MAAGMYLEHY LDSIENLPFE LQRNFQLMRD LDQRTEDLKA EIDKLATEYM SSARSLSSEE 60
KLALLKQIQE AYGKCKEFGD DKVQLAMQTY EMVDKHIRRL DTDLARFEAD LKEKQIESSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGCGG GGATGTATTT GGAACATTAT CTGGACAGTA AGAGCAGGCT GGAGGTGGGG 60
GTCGGGGCTG TAGAGTGGTG CGGGGATCAG GGATGAGAGG ATCTGTAGCC CTTAAGTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0000123--C:histone acetyltransferase complex
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0007050--P:cell cycle arrest
GO:0006978--P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0006260--P:DNA replication
GO:0043966--P:histone H3 acetylation
GO:0043983--P:histone H4-K12 acetylation
GO:0043981--P:histone H4-K5 acetylation
GO:0043982--P:histone H4-K8 acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0045926--P:negative regulation of growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001338	Ailuropoda melanoleuca	99.60	7.00e-128	449.00
IUUC-Apl-004097	Anas platyrhynchos	91.13	8.00e-118	416.00
IUUC-Aca-004593	Anolis carolinensis	93.57	2.00e-123	434.00
IUUC-Ame-011133	Astyanax mexicanus	79.68	2.00e-116	410.00
IUUC-Bta-012699	Bos taurus	98.39	1.00e-127	448.00
IUUC-Bdi-014504	Brachypodium distachyon	35.60	7.00e-40	156.00
IUUC-Bol-015245	Brassica oleracea	31.45	4.00e-30	124.00
IUUC-Bra-017027	Brassica rapa	31.85	1.00e-30	126.00
IUUC-Cja-019988	Callithrix jacchus	96.79	8.00e-120	422.00
IUUC-Cfa-021282	Canis familiaris	95.98	9.00e-119	419.00
IUUC-Cpo-022011	Cavia porcellus	95.98	4.00e-129	453.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	31.35	5.00e-29	121.00
IUUC-Csa-023203	Chlorocebus sabaeus	96.79	8.00e-120	422.00
IUUC-Cin-025479	Ciona intestinalis	62.87	1.00e-80	292.00
IUUC-Csv-026288	Ciona savignyi	55.43	4.00e-75	274.00
IUUC-Dre-028264	Danio rerio	79.28	8.00e-115	405.00
IUUC-Dno-029766	Dasypus novemcinctus	93.15	2.00e-112	397.00
IUUC-Dor-031136	Dipodomys ordii	81.36	3.00e-97	347.00
IUUC-Dme-032200	Drosophila melanogaster	84.00	2.00e-40	159.00
IUUC-Eca-033565	Equus caballus	95.98	5.00e-129	453.00
IUUC-Eeu-034948	Erinaceus europaeus	82.11	2.00e-100	358.00
IUUC-Fca-036368	Felis catus	96.39	3.00e-119	421.00
IUUC-Fal-037120	Ficedula albicollis	90.73	2.00e-116	411.00
IUUC-Gmo-038982	Gadus morhua	81.20	2.00e-114	404.00
IUUC-Gga-040771	Gallus gallus	93.57	2.00e-123	434.00
IUUC-Gac-042184	Gasterosteus aculeatus	80.89	2.00e-111	394.00
IUUC-Gma-044339	Glycine max	29.48	8.00e-34	136.00
IUUC-Ggo-045559	Gorilla gorilla	96.79	8.00e-120	422.00
IUUC-Hsa-046852	Homo sapiens	96.79	8.00e-120	422.00
IUUC-Hvu-047046	Hordeum vulgare	36.11	6.00e-37	147.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	95.58	1.00e-128	452.00
IUUC-Kpa-049229	Komagataella pastoris	59.18	1.00e-16	79.70
IUUC-Lpe-050822	Leersia perrieri	34.80	2.00e-38	152.00
IUUC-Laf-054057	Loxodonta africana	96.39	3.00e-119	421.00
IUUC-Mcc-055212	Macaca mulatta	92.03	3.00e-115	407.00
IUUC-Meu-056511	Macropus eugenii	92.80	7.00e-120	422.00
IUUC-Mga-059967	Meleagris gallopavo	91.50	2.00e-117	414.00
IUUC-Mmr-060843	Microcebus murinus	97.98	1.00e-126	445.00
IUUC-Mdo-062357	Monodelphis domestica	95.58	2.00e-128	451.00
IUUC-Mmu-064093	Mus musculus	95.98	4.00e-129	453.00
IUUC-Mpu-066923	Mustela putorius furo	82.73	2.00e-96	344.00
IUUC-Mlu-067754	Myotis lucifugus	88.89	3.00e-117	414.00
IUUC-Nle-069062	Nomascus leucogenys	96.79	8.00e-120	422.00
IUUC-Opr-070207	Ochotona princeps	88.98	4.00e-110	390.00
IUUC-Ont-072446	Oreochromis niloticus	81.60	2.00e-113	400.00
IUUC-Ocu-074235	Oryctolagus cuniculus	95.98	9.00e-119	419.00
IUUC-Obr-076266	Oryza brachyantha	34.80	6.00e-38	150.00
IUUC-Ogl-077118	Oryza glaberrima	34.52	4.00e-36	144.00
IUUC-Oin-079049	Oryza indica	33.47	2.00e-36	145.00
IUUC-Ome-081291	Oryza meridionalis	35.46	5.00e-37	147.00
IUUC-Oni-082218	Oryza nivara	33.47	2.00e-36	145.00
IUUC-Opu-084171	Oryza punctata	35.06	5.00e-37	147.00
IUUC-Osa-085563	Oryza sativa	35.46	5.00e-37	147.00
IUUC-Ola-086429	Oryzias latipes	77.20	6.00e-105	373.00
IUUC-Olu-087851	Ostreococcus lucimarinus	34.78	7.00e-20	90.50
IUUC-Oga-089123	Otolemur garnettii	96.39	3.00e-119	421.00
IUUC-Oar-089524	Ovis aries	98.39	1.00e-127	448.00
IUUC-Ptr-090908	Pan troglodytes	96.39	3.00e-119	421.00
IUUC-Psi-093828	Pelodiscus sinensis	93.13	2.00e-112	397.00
IUUC-Ppa-096009	Physcomitrella patens	33.98	1.00e-33	136.00
IUUC-Pfo-096617	Poecilia formosa	81.20	2.00e-113	401.00
IUUC-Pab-097978	Pongo abelii	96.19	3.00e-109	387.00
IUUC-Pop-099415	Populus trichocarpa	73.68	2.00e-26	112.00
IUUC-Pca-100475	Procavia capensis	65.46	7.00e-84	303.00
IUUC-Ppe-101441	Prunus persica	32.94	1.00e-36	145.00
IUUC-Pva-102325	Pteropus vampyrus	95.98	5.00e-129	453.00
IUUC-Rno-105178	Rattus norvegicus	97.98	2.00e-136	477.00
IUUC-Sha-106773	Sarcophilus harrisii	95.58	2.00e-128	451.00
IUUC-Sit-109827	Setaria italica	36.00	1.00e-36	145.00
IUUC-Sly-111750	Solanum lycopersicum	34.00	4.00e-36	144.00
IUUC-Stu-112250	Solanum tuberosum	34.00	4.00e-36	144.00
IUUC-Sbi-114826	Sorghum bicolor	36.00	2.00e-37	149.00
IUUC-Sre-115124	Sporisorium reilianum	58.21	2.00e-22	100.00
IUUC-Ssc-115797	Sus scrofa	89.43	2.00e-103	368.00
IUUC-Tgu-117270	Taeniopygia guttata	93.57	2.00e-123	434.00
IUUC-Tru-118253	Takifugu rubripes	80.88	4.00e-114	403.00
IUUC-Tca-121597	Theobroma cacao	69.84	3.00e-28	118.00
IUUC-Tae-123043	Triticum aestivum	35.43	1.00e-38	153.00
IUUC-Tbe-127558	Tupaia belangeri	99.60	7.00e-128	449.00
IUUC-Ttr-128300	Tursiops truncatus	99.09	3.00e-65	241.00
IUUC-Uma-129581	Ustilago maydis	57.63	3.00e-21	97.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence