iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000000379.2	ENSORLT00000000467.1	ENSORLP00000000467.1
ENSORLG00000000379.2	ENSORLT00000000465.2	ENSORLP00000000465.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.80e-09	37.2	12	53
UBD/SH3	4.60e-37	126.1	405	460

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Clq +     ss++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCRRCLQGI----LSSRGELRCPECR 53
           **********9***************999....89**********8 PP

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
             ++++y++ ++deL+l+kG++ lv+ + +   gW kg++  +gk G+fP n++  ++
   Q: 405  YVAMFPYTPRKEDELELRKGEMFLVL-ERC-QDGWFKGTSMHTGKIGVFPGNYMSPVS 460
           6799**********************.555.569*******************99875 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MDESVLLDLL ECPVCLERLD ASAKVLPCQH TFCRRCLQGI LSSRGELRCP ECRTLVECAV 60
DDLPSNILLV RLLDGIKQRP RKAGAGPAVC TNGTPGATAR AQGAGTKDQN GPGAPTQRAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCCGCTGC TTCCACGCTC CTTTTCATCG TAGAATTCAC CCACGTCTCC TCTCTGGTAG 60
GTTTTGGCCT CGAGTTGCTA AACGGGAACT CTCTCGGCCG AATGGCGGTT CTTGTCGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF14604--SH3_9
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0046328--P:regulation of JNK cascade

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	62.21	1.00e-171	596.00
IUUC-Apl-003961	Anas platyrhynchos	60.00	0.00e+00	636.00
IUUC-Aca-004386	Anolis carolinensis	56.47	0.00e+00	732.00
IUUC-Ame-010659	Astyanax mexicanus	68.40	0.00e+00	939.00
IUUC-Bta-012563	Bos taurus	58.92	4.00e-113	402.00
IUUC-Cja-019730	Callithrix jacchus	67.85	5.00e-124	438.00
IUUC-Cfa-020992	Canis familiaris	68.12	2.00e-126	446.00
IUUC-Cpo-021304	Cavia porcellus	60.48	2.00e-174	606.00
IUUC-Csa-023925	Chlorocebus sabaeus	68.39	3.00e-127	449.00
IUUC-Cho-024630	Choloepus hoffmanni	53.96	3.00e-101	363.00
IUUC-Cin-025274	Ciona intestinalis	43.04	5.00e-59	221.00
IUUC-Csv-026136	Ciona savignyi	38.94	3.00e-59	222.00
IUUC-Dre-028290	Danio rerio	68.81	0.00e+00	924.00
IUUC-Dno-029083	Dasypus novemcinctus	60.19	4.00e-176	611.00
IUUC-Dor-030388	Dipodomys ordii	68.80	3.00e-122	432.00
IUUC-Dme-032207	Drosophila melanogaster	39.49	2.00e-53	204.00
IUUC-Ete-032809	Echinops telfairi	49.80	3.00e-107	382.00
IUUC-Eca-034185	Equus caballus	69.33	6.00e-80	291.00
IUUC-Eeu-034816	Erinaceus europaeus	59.62	4.00e-102	365.00
IUUC-Fca-036439	Felis catus	61.32	4.00e-173	601.00
IUUC-Fal-037074	Ficedula albicollis	60.16	3.00e-179	622.00
IUUC-Gmo-039443	Gadus morhua	64.05	1.00e-123	437.00
IUUC-Gga-040749	Gallus gallus	62.24	2.00e-179	622.00
IUUC-Gac-041420	Gasterosteus aculeatus	74.85	0.00e+00	757.00
IUUC-Ggo-045215	Gorilla gorilla	68.12	8.00e-127	447.00
IUUC-Hsa-046315	Homo sapiens	67.85	1.00e-126	447.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	38.24	3.00e-75	276.00
IUUC-Lch-049453	Latimeria chalumnae	58.07	7.00e-139	487.00
IUUC-Laf-053651	Loxodonta africana	62.42	2.00e-172	599.00
IUUC-Mcc-054688	Macaca mulatta	68.12	6.00e-127	448.00
IUUC-Meu-056291	Macropus eugenii	51.78	2.00e-122	433.00
IUUC-Mga-059944	Meleagris gallopavo	57.59	0.00e+00	735.00
IUUC-Mmr-061553	Microcebus murinus	68.12	2.00e-126	446.00
IUUC-Mdo-062313	Monodelphis domestica	52.86	0.00e+00	660.00
IUUC-Mmu-063516	Mus musculus	55.94	6.00e-174	604.00
IUUC-Mpu-066064	Mustela putorius furo	60.58	8.00e-170	590.00
IUUC-Mlu-067312	Myotis lucifugus	60.16	1.00e-165	577.00
IUUC-Nle-069035	Nomascus leucogenys	68.12	6.00e-127	448.00
IUUC-Opr-070739	Ochotona princeps	44.57	2.00e-70	260.00
IUUC-Ont-071484	Oreochromis niloticus	79.06	0.00e+00	1079.00
IUUC-Oan-073305	Ornithorhynchus anatinus	61.01	0.00e+00	630.00
IUUC-Ocu-074936	Oryctolagus cuniculus	67.57	1.00e-125	443.00
IUUC-Oga-087933	Otolemur garnettii	57.11	3.00e-121	429.00
IUUC-Oar-090408	Ovis aries	58.35	1.00e-110	393.00
IUUC-Ptr-090865	Pan troglodytes	68.12	7.00e-127	447.00
IUUC-Pan-092362	Papio anubis	68.12	1.00e-126	447.00
IUUC-Psi-093876	Pelodiscus sinensis	59.69	2.00e-176	612.00
IUUC-Ppa-095766	Physcomitrella patens	38.03	5.00e-07	47.80
IUUC-Pfo-097116	Poecilia formosa	78.65	0.00e+00	1087.00
IUUC-Pab-098127	Pongo abelii	68.12	9.00e-127	447.00
IUUC-Pca-100485	Procavia capensis	61.88	7.00e-173	600.00
IUUC-Pva-102661	Pteropus vampyrus	67.30	3.00e-125	442.00
IUUC-Rno-105728	Rattus norvegicus	67.56	3.00e-122	432.00
IUUC-Sha-106515	Sarcophilus harrisii	61.19	1.00e-164	572.00
IUUC-Sar-113161	Sorex araneus	67.60	3.00e-117	416.00
IUUC-Ssc-115314	Sus scrofa	61.56	2.00e-170	592.00
IUUC-Tgu-117012	Taeniopygia guttata	59.26	0.00e+00	638.00
IUUC-Tru-118467	Takifugu rubripes	77.90	0.00e+00	692.00
IUUC-Tsy-119566	Tarsius syrichta	61.48	2.00e-106	379.00
IUUC-Tni-120830	Tetraodon nigroviridis	68.35	0.00e+00	775.00
IUUC-Tbe-128070	Tupaia belangeri	68.66	6.00e-127	448.00
IUUC-Ttr-128161	Tursiops truncatus	67.45	2.00e-87	317.00
IUUC-Vpa-130075	Vicugna pacos	53.28	6.00e-31	129.00
IUUC-Xtr-132628	Xenopus tropicalis	60.54	0.00e+00	627.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence