iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000003400.3	ENSMMUT00000004807.3	ENSMMUP00000004533.3
ENSMMUG00000003400.3	ENSMMUT00000074933.1	ENSMMUP00000049290.1
ENSMMUG00000003400.3	ENSMMUT00000061084.1	ENSMMUP00000053532.1
ENSMMUG00000003400.3	ENSMMUT00000059948.1	ENSMMUP00000045003.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	29.67	1.00e-65	248.00	IUUC-Dme-031819
E3 activity/RING/RING	86.59	0.00e+00	1014.00	IUUC-Hsa-046144
UBD/Alpha-Helix/UBA	86.59	0.00e+00	1014.00	IUUC-Hsa-046144

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MNIVENSIFL SNLMKSANTF ELKYDLSCEL YRMSTYSAFP AGVPVSERSL ARAGFYYTGV 60
NDKVKCFCCG LMLDNWKRGD SPVEKHKKLY PSCRFVQSLN SVNNSEATSQ PAFPSSVTNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAACATAG TAGAAAATAG CATATTCTTA TCAAATTTGA TGAAAAGTGC CAACACGTTT 60
GAACTGAAAT ACGACTTGTC ATGTGAACTG TACCGAATGT CTACGTATTC TGCTTTTCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0005737--C:cytoplasm
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0043027--F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071356--P:cellular response to tumor necrosis factor
GO:1990001--P:inhibition of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070266--P:necroptotic process
GO:0060546--P:negative regulation of necroptotic process
GO:1902443--P:negative regulation of ripoptosome assembly involved in necroptotic process
GO:0001890--P:placenta development
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:1902523--P:positive regulation of protein K63-linked ubiquitination
GO:1902527--P:positive regulation of protein monoubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:1901222--P:regulation of NIK/NF-kappaB signaling
GO:2000377--P:regulation of reactive oxygen species metabolic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002369	Ailuropoda melanoleuca	80.79	0.00e+00	938.00
IUUC-Atr-002499	Amborella trichopoda	44.64	4.00e-12	65.50
IUUC-Apl-003549	Anas platyrhynchos	73.36	0.00e+00	848.00
IUUC-Aca-004515	Anolis carolinensis	68.00	0.00e+00	775.00
IUUC-Aly-006460	Arabidopsis lyrata	37.04	3.00e-09	55.80
IUUC-Ath-007365	Arabidopsis thaliana	30.67	7.00e-08	55.50
IUUC-Acl-008330	Aspergillus clavatus	29.74	5.00e-15	76.60
IUUC-Afl-008648	Aspergillus flavus	29.84	2.00e-15	77.80
IUUC-Afu-008813	Aspergillus fumigatus	29.79	7.00e-15	76.30
IUUC-Ani-009424	Aspergillus nidulans	28.81	2.00e-15	77.80
IUUC-Ang-009667	Aspergillus niger	30.43	2.00e-13	70.90
IUUC-Ate-010501	Aspergillus terreus	32.10	2.00e-16	81.60
IUUC-Ame-011877	Astyanax mexicanus	54.83	0.00e+00	653.00
IUUC-Bgr-012051	Blumeria graminis	32.90	1.00e-11	65.50
IUUC-Bta-013105	Bos taurus	76.49	0.00e+00	873.00
IUUC-Bci-013905	Botrytis cinerea	35.19	1.00e-16	81.60
IUUC-Bol-015478	Brassica oleracea	32.76	4.00e-10	63.20
IUUC-Bra-017001	Brassica rapa	33.62	2.00e-10	63.90
IUUC-Cel-018418	Caenorhabditis elegans	40.68	2.00e-08	53.10
IUUC-Cja-018895	Callithrix jacchus	83.44	0.00e+00	942.00
IUUC-Cfa-020419	Canis familiaris	80.90	0.00e+00	952.00
IUUC-Cpo-022048	Cavia porcellus	80.76	0.00e+00	937.00
IUUC-Csa-024159	Chlorocebus sabaeus	99.50	0.00e+00	1150.00
IUUC-Cho-024929	Choloepus hoffmanni	79.80	0.00e+00	910.00
IUUC-Cin-025521	Ciona intestinalis	30.86	3.00e-76	279.00
IUUC-Csv-026182	Ciona savignyi	31.48	1.00e-67	251.00
IUUC-Cgl-026472	Colletotrichum gloeosporioides	38.65	2.00e-20	95.10
IUUC-Cne-027029	Cryptococcus neoformans	32.37	3.00e-13	70.10
IUUC-Dre-028647	Danio rerio	55.73	0.00e+00	649.00
IUUC-Dno-029509	Dasypus novemcinctus	87.25	0.00e+00	1013.00
IUUC-Dor-030796	Dipodomys ordii	73.78	7.00e-99	354.00
IUUC-Dme-031819	Drosophila melanogaster	28.67	2.00e-69	256.00
IUUC-Ete-032768	Echinops telfairi	68.87	0.00e+00	728.00
IUUC-Eca-034417	Equus caballus	83.94	0.00e+00	977.00
IUUC-Eeu-035114	Erinaceus europaeus	79.77	0.00e+00	906.00
IUUC-Fca-036034	Felis catus	80.70	0.00e+00	919.00
IUUC-Fal-037656	Ficedula albicollis	72.83	0.00e+00	849.00
IUUC-Fox-037889	Fusarium oxysporum	33.33	2.00e-15	77.80
IUUC-Fso-038452	Fusarium solani	33.33	6.00e-14	73.20
IUUC-Gmo-038477	Gadus morhua	55.21	2.00e-176	612.00
IUUC-Ggr-039891	Gaeumannomyces graminis	33.14	2.00e-17	84.30
IUUC-Gga-040601	Gallus gallus	72.34	0.00e+00	851.00
IUUC-Gac-041467	Gasterosteus aculeatus	55.65	3.00e-178	618.00
IUUC-Ggo-044605	Gorilla gorilla	86.78	0.00e+00	1006.00
IUUC-Hsa-046144	Homo sapiens	86.59	0.00e+00	1012.00
IUUC-Itr-048379	Ictidomys tridecemlineatus	83.44	0.00e+00	965.00
IUUC-Kpa-049324	Komagataella pastoris	30.59	2.00e-13	72.00
IUUC-Lch-050259	Latimeria chalumnae	62.66	0.00e+00	729.00
IUUC-Loc-052169	Lepisosteus oculatus	54.68	2.00e-172	598.00
IUUC-Lma-052958	Leptosphaeria maculans	34.67	2.00e-13	71.20
IUUC-Laf-053720	Loxodonta africana	82.36	0.00e+00	933.00
IUUC-Meu-056241	Macropus eugenii	68.45	0.00e+00	707.00
IUUC-Mor-057252	Magnaporthe oryzae	34.30	7.00e-18	86.30
IUUC-Mpo-057489	Magnaporthe poae	33.72	5.00e-17	83.20
IUUC-Mtr-058211	Medicago truncatula	34.91	9.00e-09	58.50
IUUC-Mga-059947	Meleagris gallopavo	72.50	0.00e+00	856.00
IUUC-Mvi-060388	Microbotryum violaceum	25.50	2.00e-06	48.10
IUUC-Mmr-060719	Microcebus murinus	84.60	0.00e+00	991.00
IUUC-Mdo-062352	Monodelphis domestica	78.31	0.00e+00	909.00
IUUC-Mmu-064340	Mus musculus	76.53	0.00e+00	892.00
IUUC-Mac-065489	Musa acuminata	36.73	4.00e-08	52.00
IUUC-Mpu-065890	Mustela putorius furo	80.77	0.00e+00	892.00
IUUC-Mlu-068077	Myotis lucifugus	82.64	0.00e+00	967.00
IUUC-Nfi-068591	Neosartorya fischeri	29.17	2.00e-14	74.70
IUUC-Ncr-068787	Neurospora crassa	34.38	6.00e-15	76.30
IUUC-Nle-069942	Nomascus leucogenys	86.42	0.00e+00	1000.00
IUUC-Opr-070597	Ochotona princeps	80.13	0.00e+00	939.00
IUUC-Ont-071776	Oreochromis niloticus	54.49	0.00e+00	640.00
IUUC-Oan-073604	Ornithorhynchus anatinus	77.92	0.00e+00	913.00
IUUC-Ocu-074698	Oryctolagus cuniculus	83.77	0.00e+00	998.00
IUUC-Ogu-078452	Oryza glumaepatula	45.45	5.00e-07	48.90
IUUC-Olo-080871	Oryza longistaminata	39.58	2.00e-06	47.80
IUUC-Oni-082044	Oryza nivara	41.82	2.00e-09	57.00
IUUC-Opu-084085	Oryza punctata	39.58	2.00e-06	46.60
IUUC-Oru-085060	Oryza rufipogon	44.19	1.00e-06	47.80
IUUC-Ola-086446	Oryzias latipes	52.83	8.00e-174	603.00
IUUC-Oga-087976	Otolemur garnettii	82.75	0.00e+00	945.00
IUUC-Oar-089496	Ovis aries	83.11	0.00e+00	951.00
IUUC-Ptr-091203	Pan troglodytes	86.59	0.00e+00	1008.00
IUUC-Pan-092673	Papio anubis	85.26	0.00e+00	963.00
IUUC-Psi-092992	Pelodiscus sinensis	72.01	0.00e+00	856.00
IUUC-Pma-094277	Petromyzon marinus	37.52	7.00e-114	404.00
IUUC-Pno-094971	Phaeosphaeria nodorum	36.42	5.00e-15	76.30
IUUC-Ppa-095167	Physcomitrella patens	42.86	2.00e-11	63.20
IUUC-Pfo-096790	Poecilia formosa	54.15	2.00e-177	615.00
IUUC-Pab-098734	Pongo abelii	84.55	0.00e+00	953.00
IUUC-Pop-098944	Populus trichocarpa	42.59	6.00e-10	58.20
IUUC-Pca-100708	Procavia capensis	75.00	6.00e-176	610.00
IUUC-Ppe-101533	Prunus persica	43.48	2.00e-07	54.30
IUUC-Pva-102788	Pteropus vampyrus	83.28	0.00e+00	956.00
IUUC-Pte-104098	Pyrenophora teres	35.09	2.00e-17	83.60
IUUC-Pyt-104561	Pyrenophora triticirepentis	34.50	2.00e-17	83.60
IUUC-Rno-105026	Rattus norvegicus	75.79	0.00e+00	885.00
IUUC-Sha-107229	Sarcophilus harrisii	72.35	0.00e+00	838.00
IUUC-Sja-107720	Schizosaccharomyces japonicus	32.48	4.00e-15	77.00
IUUC-Spo-108317	Schizosaccharomyces pombe	28.93	2.00e-16	81.60
IUUC-Sar-113239	Sorex araneus	75.21	0.00e+00	840.00
IUUC-Ssc-115804	Sus scrofa	80.66	0.00e+00	934.00
IUUC-Tgu-116931	Taeniopygia guttata	73.16	0.00e+00	867.00
IUUC-Tru-117620	Takifugu rubripes	52.38	3.00e-180	625.00
IUUC-Tsy-118958	Tarsius syrichta	80.61	1.00e-168	586.00
IUUC-Tni-119683	Tetraodon nigroviridis	53.93	3.00e-180	625.00
IUUC-Tre-121884	Trichoderma reesei	34.16	9.00e-14	72.40
IUUC-Tvi-122552	Trichoderma virens	34.38	6.00e-14	73.20
IUUC-Tbe-127523	Tupaia belangeri	81.52	0.00e+00	936.00
IUUC-Ttr-128766	Tursiops truncatus	83.77	0.00e+00	975.00
IUUC-Vpa-130761	Vicugna pacos	85.26	0.00e+00	996.00
IUUC-Xtr-132031	Xenopus tropicalis	59.28	0.00e+00	642.00
IUUC-Xma-132984	Xiphophorus maculatus	53.53	8.00e-179	620.00
IUUC-Yli-134629	Yarrowia lipolytica	34.81	1.00e-17	84.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence