iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000005775.4	ENSCAFT00000009352.4	ENSCAFP00000008679.3
ENSCAFG00000005775.4	ENSCAFT00000047924.1	ENSCAFP00000042691.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.60e-34	117.8	4475	4631

Active Site

Position(s)	Description	Evidence
4564	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp....egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.....ifhPnvyen 78
           Rl++e+ +l+++ p    +++++++++e  l+ ++vli+Gp+dtpY++g+F+++++fp+dYP++PP v+++t+     +f+Pn+y++
   Q: 4475 RLAQEAVTLSTSLPlsssSSVFVRCDEE-RLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTgghsvRFNPNLYND 4560
           8999999999998877768899999999.6********************************************************* PP
   S: 79   GkvClsilk.....eeekWsp.alsvesvllsiqsll..aepnpesplneeaa...ellkknreeykkkvre 139
           GkvClsil+     +eekW+p ++s+ +vl+s+qsl+  aep++++p +e+++   + ++++re y+ ++r+
   Q: 4561 GKVCLSILNtwhgrPEEKWNPqTSSFLQVLVSVQSLIlvAEPYFNEPGYERSRgtpSGTQSSRE-YDGNIRQ 4631
           ********7788889******8899***********999***********99866555666655.9998875 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

LTAKPGGQVK CQYISAVDKV IFVDDYAVGC RKDLNGILLL DTALQTPVSK QDDVVQLELP 60
VTEAQQLLSA CLEKVDISST EGYDLFITQL KDGLKNTSHE TAANHKVAKW ATVTFHLPHH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAACAGCTA AACCAGGTGG ACAGGTGAAA TGTCAGTATA TATCTGCGGT GGATAAAGTT 60
ATATTTGTGG ATGATTATGC AGTAGGGTGT AGGAAGGACC TTAATGGAAT CTTGTTGTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001370--BIR_rpt
IPR022103--BIRC6
IPR008979--Galactose-bd-like
IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50143--BIR_REPEAT_2
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00653--BIR
PF12356--BIRC6
PF00179--UQ_con

SMART

SM00238--BIR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005768--C:endosome
GO:0016020--C:membrane
GO:0005815--C:microtubule organizing center
GO:0030496--C:midbody
GO:0000922--C:spindle pole
GO:0005802--C:trans-Golgi network
GO:0004869--F:cysteine-type endopeptidase inhibitor activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006915--P:apoptotic process
GO:0060711--P:labyrinthine layer development
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0008284--P:positive regulation of cell proliferation
GO:0032465--P:regulation of cytokinesis
GO:0009966--P:regulation of signal transduction
GO:0060712--P:spongiotrophoblast layer development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001583	Ailuropoda melanoleuca	99.22	0.00e+00	8775.00
IUUC-Atr-003108	Amborella trichopoda	42.86	3.00e-45	176.00
IUUC-Apl-004144	Anas platyrhynchos	92.36	0.00e+00	5637.00
IUUC-Aca-005257	Anolis carolinensis	89.64	0.00e+00	7970.00
IUUC-Ath-007217	Arabidopsis thaliana	45.76	7.00e-44	171.00
IUUC-Ame-011337	Astyanax mexicanus	77.73	0.00e+00	6581.00
IUUC-Bta-012501	Bos taurus	97.23	0.00e+00	8515.00
IUUC-Bdi-014931	Brachypodium distachyon	37.05	2.00e-46	180.00
IUUC-Bol-015976	Brassica oleracea	46.33	9.00e-46	177.00
IUUC-Bra-017967	Brassica rapa	46.33	4.00e-46	178.00
IUUC-Cel-018661	Caenorhabditis elegans	36.34	5.00e-79	289.00
IUUC-Cja-018746	Callithrix jacchus	97.67	0.00e+00	8575.00
IUUC-Cpo-022138	Cavia porcellus	97.05	0.00e+00	5828.00
IUUC-Cre-022768	Chlamydomonas reinhardtii	44.69	1.00e-44	172.00
IUUC-Csa-023927	Chlorocebus sabaeus	97.53	0.00e+00	8554.00
IUUC-Cho-024890	Choloepus hoffmanni	94.15	0.00e+00	1942.00
IUUC-Cne-026995	Cryptococcus neoformans	42.62	2.00e-37	151.00
IUUC-Dre-027941	Danio rerio	78.22	0.00e+00	5228.00
IUUC-Dno-028913	Dasypus novemcinctus	95.91	0.00e+00	8464.00
IUUC-Dor-030715	Dipodomys ordii	94.47	0.00e+00	1942.00
IUUC-Dse-031232	Dothistroma septosporum	44.51	5.00e-38	153.00
IUUC-Dme-031592	Drosophila melanogaster	52.91	0.00e+00	672.00
IUUC-Ete-032587	Echinops telfairi	77.89	0.00e+00	2075.00
IUUC-Eca-033819	Equus caballus	98.22	0.00e+00	8616.00
IUUC-Eeu-034863	Erinaceus europaeus	87.45	0.00e+00	2558.00
IUUC-Fca-035505	Felis catus	97.19	0.00e+00	8444.00
IUUC-Fal-037318	Ficedula albicollis	92.21	0.00e+00	8158.00
IUUC-Gmo-039521	Gadus morhua	81.47	0.00e+00	1689.00
IUUC-Ggr-040040	Gaeumannomyces graminis	47.06	2.00e-33	138.00
IUUC-Gga-040728	Gallus gallus	92.10	0.00e+00	8079.00
IUUC-Gac-042251	Gasterosteus aculeatus	84.79	0.00e+00	1792.00
IUUC-Ggo-045562	Gorilla gorilla	95.98	0.00e+00	1589.00
IUUC-Hsa-046339	Homo sapiens	97.92	0.00e+00	8519.00
IUUC-Hvu-047441	Hordeum vulgare	46.70	4.00e-47	182.00
IUUC-Itr-048099	Ictidomys tridecemlineatus	97.11	0.00e+00	2708.00
IUUC-Lch-050164	Latimeria chalumnae	85.84	0.00e+00	7442.00
IUUC-Lpe-051294	Leersia perrieri	40.23	3.00e-47	182.00
IUUC-Loc-052800	Lepisosteus oculatus	84.93	0.00e+00	7414.00
IUUC-Laf-054034	Loxodonta africana	96.78	0.00e+00	8517.00
IUUC-Mcc-055267	Macaca mulatta	97.67	0.00e+00	8546.00
IUUC-Meu-056461	Macropus eugenii	93.95	0.00e+00	1249.00
IUUC-Mpo-057396	Magnaporthe poae	49.03	2.00e-34	141.00
IUUC-Mtr-057797	Medicago truncatula	39.52	3.00e-47	182.00
IUUC-Mla-059114	Melampsora laricipopulina	28.31	4.00e-41	163.00
IUUC-Mga-059594	Meleagris gallopavo	92.02	0.00e+00	7757.00
IUUC-Mmr-061179	Microcebus murinus	97.57	0.00e+00	8532.00
IUUC-Mdo-062990	Monodelphis domestica	93.92	0.00e+00	8115.00
IUUC-Mmu-063825	Mus musculus	94.91	0.00e+00	8328.00
IUUC-Mac-064881	Musa acuminata	43.41	5.00e-42	165.00
IUUC-Mpu-065908	Mustela putorius furo	98.49	0.00e+00	5626.00
IUUC-Mlu-067106	Myotis lucifugus	96.86	0.00e+00	8544.00
IUUC-Nle-069347	Nomascus leucogenys	98.00	0.00e+00	8575.00
IUUC-Opr-070799	Ochotona princeps	87.33	0.00e+00	2547.00
IUUC-Ont-072046	Oreochromis niloticus	79.08	0.00e+00	6800.00
IUUC-Oan-073415	Ornithorhynchus anatinus	92.96	0.00e+00	3400.00
IUUC-Ocu-074556	Oryctolagus cuniculus	97.09	0.00e+00	8485.00
IUUC-Oba-075602	Oryza barthii	39.26	3.00e-40	159.00
IUUC-Obr-076463	Oryza brachyantha	36.34	2.00e-47	182.00
IUUC-Ogl-077040	Oryza glaberrima	39.26	3.00e-40	159.00
IUUC-Ogu-078917	Oryza glumaepatula	39.26	3.00e-40	159.00
IUUC-Oin-079561	Oryza indica	39.26	3.00e-40	159.00
IUUC-Olo-080416	Oryza longistaminata	40.74	7.00e-41	163.00
IUUC-Ome-081384	Oryza meridionalis	39.26	4.00e-40	159.00
IUUC-Oni-082241	Oryza nivara	39.26	3.00e-40	159.00
IUUC-Opu-083659	Oryza punctata	38.04	1.00e-46	181.00
IUUC-Oru-084622	Oryza rufipogon	39.26	3.00e-40	159.00
IUUC-Osa-085920	Oryza sativa	39.26	3.00e-40	159.00
IUUC-Ola-087459	Oryzias latipes	82.09	0.00e+00	2883.00
IUUC-Oga-088251	Otolemur garnettii	94.96	0.00e+00	8126.00
IUUC-Oar-090367	Ovis aries	97.55	0.00e+00	8522.00
IUUC-Ptr-091512	Pan troglodytes	97.94	0.00e+00	8561.00
IUUC-Pan-092222	Papio anubis	97.27	0.00e+00	8516.00
IUUC-Pma-094574	Petromyzon marinus	61.30	0.00e+00	2997.00
IUUC-Ppa-095592	Physcomitrella patens	29.31	2.00e-54	207.00
IUUC-Pfo-097086	Poecilia formosa	77.59	0.00e+00	6732.00
IUUC-Pab-098390	Pongo abelii	96.19	0.00e+00	8334.00
IUUC-Pop-099284	Populus trichocarpa	37.75	3.00e-42	166.00
IUUC-Pca-101036	Procavia capensis	89.01	0.00e+00	4145.00
IUUC-Pva-103053	Pteropus vampyrus	93.30	0.00e+00	3525.00
IUUC-Pte-104333	Pyrenophora teres	41.29	8.00e-44	173.00
IUUC-Pyt-104498	Pyrenophora triticirepentis	39.39	3.00e-44	173.00
IUUC-Rno-106049	Rattus norvegicus	95.51	0.00e+00	6814.00
IUUC-Sha-107483	Sarcophilus harrisii	91.08	0.00e+00	7799.00
IUUC-Smo-108915	Selaginella moellendorffii	42.96	2.00e-44	172.00
IUUC-Sly-110929	Solanum lycopersicum	38.55	2.00e-46	180.00
IUUC-Stu-112554	Solanum tuberosum	38.96	9.00e-47	181.00
IUUC-Sar-112965	Sorex araneus	86.46	0.00e+00	1815.00
IUUC-Sbi-113880	Sorghum bicolor	35.76	3.00e-45	176.00
IUUC-Ssc-115927	Sus scrofa	98.19	0.00e+00	6028.00
IUUC-Tgu-117132	Taeniopygia guttata	92.24	0.00e+00	8143.00
IUUC-Tru-118115	Takifugu rubripes	75.73	0.00e+00	6566.00
IUUC-Tsy-118899	Tarsius syrichta	94.90	0.00e+00	5095.00
IUUC-Tni-120891	Tetraodon nigroviridis	74.84	0.00e+00	6534.00
IUUC-Tae-125407	Triticum aestivum	47.25	3.00e-47	183.00
IUUC-Tur-126479	Triticum urartu	46.41	2.00e-43	170.00
IUUC-Tme-126930	Tuber melanosporum	42.60	6.00e-48	186.00
IUUC-Tbe-127630	Tupaia belangeri	93.74	0.00e+00	1553.00
IUUC-Ttr-128629	Tursiops truncatus	96.03	0.00e+00	8412.00
IUUC-Vpa-130310	Vicugna pacos	97.38	0.00e+00	8415.00
IUUC-Xtr-131861	Xenopus tropicalis	83.84	0.00e+00	7180.00
IUUC-Xma-133613	Xiphophorus maculatus	77.95	0.00e+00	6709.00
IUUC-Zma-135768	Zea mays	35.67	8.00e-46	179.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence