iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005040

Ensembl Protein ID

ENSACAP00000005074.3

UniProt Accession

G1KDQ6; G1KDQ6_ANOCA

Protein Name

Uncharacterized protein

Gene Name

EP300

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000005148.3	ENSACAT00000005189.3	ENSACAP00000005074.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	81.26	0.00e+00	1842.00	IUUC-Hsa-046884

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAENVVESGP PSAKRPKLSS PALSVSASDG TDFGSLFDLE HDLPDELISS TELGLTNGGD 60
INQLPTSLGM AQDAASKHKQ LSELLRAGSS PNLNMGVGGP GQGMATQPQQ NNPGMGILNS 120

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Nucleotide Sequence
(Fasta)

ATGGCCGAGA ATGTGGTGGA GTCGGGCCCG CCTTCAGCCA AGAGGCCTAA ACTATCTTCA 60
CCGGCTCTCT CTGTCTCTGC AAGCGATGGC ACAGGTCAGT GTTGGGGACA GATTCCCCTC 120

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Sequence Source

Ensembl

Keyword

KW-0012--Acyltransferase
KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR031162--CBP_P300_HAT
IPR013178--Histone_AcTrfase_Rtt109/CBP
IPR003101--KIX_dom
IPR009110--Nuc_rcpt_coact
IPR014744--Nuc_rcpt_coact_CREBbp
IPR010303--RING_CBP-p300
IPR001781--Znf_LIM
IPR000197--Znf_TAZ
IPR000433--Znf_ZZ

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51727--CBP_P300_HAT
PS50952--KIX
PS50134--ZF_TAZ
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00439--Bromodomain
PF09030--Creb_binding
PF06001--DUF902
PF08214--HAT_KAT11
PF02172--KIX
PF02135--zf-TAZ
PF00569--ZZ

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM01250--KAT11
SM00551--ZnF_TAZ
SM00291--ZnF_ZZ

Gene Ontology

GO:0005829--C:cytosol
GO:0000123--C:histone acetyltransferase complex
GO:0005667--C:transcription factor complex
GO:0031490--F:chromatin DNA binding
GO:0003684--F:damaged DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0004468--F:lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0097157--F:pre-mRNA intronic binding
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0001228--F:transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0009887--P:animal organ morphogenesis
GO:0030183--P:B cell differentiation
GO:0034644--P:cellular response to UV
GO:0007623--P:circadian rhythm
GO:0045444--P:fat cell differentiation
GO:0007507--P:heart development
GO:0043969--P:histone H2B acetylation
GO:0043967--P:histone H4 acetylation
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0030324--P:lung development
GO:0010742--P:macrophage derived foam cell differentiation
GO:0035855--P:megakaryocyte development
GO:0018076--P:N-terminal peptidyl-lysine acetylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030220--P:platelet formation
GO:0043923--P:positive regulation by host of viral transcription
GO:0032092--P:positive regulation of protein binding
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0006990--P:positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0050821--P:protein stabilization
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0090043--P:regulation of tubulin deacetylation
GO:0043627--P:response to estrogen
GO:0001666--P:response to hypoxia
GO:0007519--P:skeletal muscle tissue development
GO:0001756--P:somitogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001156	Aegilops tauschii	37.66	4.00e-67	250.00
IUUC-Aml-002027	Ailuropoda melanoleuca	79.28	0.00e+00	1664.00
IUUC-Ath-007233	Arabidopsis thaliana	37.12	1.00e-73	272.00
IUUC-Ame-011395	Astyanax mexicanus	87.78	0.00e+00	1453.00
IUUC-Bta-012649	Bos taurus	79.81	0.00e+00	1746.00
IUUC-Cel-018691	Caenorhabditis elegans	50.81	0.00e+00	840.00
IUUC-Cja-019649	Callithrix jacchus	80.13	0.00e+00	1821.00
IUUC-Cfa-020764	Canis familiaris	85.44	0.00e+00	1571.00
IUUC-Cpo-022345	Cavia porcellus	75.74	0.00e+00	2778.00
IUUC-Cre-022852	Chlamydomonas reinhardtii	34.84	8.00e-65	242.00
IUUC-Csa-023866	Chlorocebus sabaeus	81.68	0.00e+00	1774.00
IUUC-Cho-024951	Choloepus hoffmanni	87.67	0.00e+00	1105.00
IUUC-Cin-025624	Ciona intestinalis	61.75	0.00e+00	1061.00
IUUC-Csv-026122	Ciona savignyi	64.16	0.00e+00	671.00
IUUC-Dre-028500	Danio rerio	77.98	0.00e+00	1456.00
IUUC-Ete-032979	Echinops telfairi	77.07	0.00e+00	1500.00
IUUC-Eca-034048	Equus caballus	82.90	0.00e+00	1640.00
IUUC-Fca-035891	Felis catus	82.57	0.00e+00	1778.00
IUUC-Fal-037585	Ficedula albicollis	86.82	0.00e+00	1914.00
IUUC-Gmo-039348	Gadus morhua	85.31	0.00e+00	1441.00
IUUC-Gga-040916	Gallus gallus	85.30	0.00e+00	1964.00
IUUC-Gac-041642	Gasterosteus aculeatus	86.03	0.00e+00	1399.00
IUUC-Ggo-045189	Gorilla gorilla	81.41	0.00e+00	1776.00
IUUC-Hsa-046884	Homo sapiens	82.85	0.00e+00	1783.00
IUUC-Hvu-047619	Hordeum vulgare	37.66	4.00e-67	250.00
IUUC-Itr-048564	Ictidomys tridecemlineatus	83.70	0.00e+00	1630.00
IUUC-Laf-054423	Loxodonta africana	81.14	0.00e+00	1862.00
IUUC-Mcc-054847	Macaca mulatta	82.20	0.00e+00	1784.00
IUUC-Meu-056217	Macropus eugenii	81.57	0.00e+00	1835.00
IUUC-Mtr-058740	Medicago truncatula	38.01	4.00e-67	250.00
IUUC-Mga-059250	Meleagris gallopavo	81.62	0.00e+00	1979.00
IUUC-Mmr-061496	Microcebus murinus	81.93	0.00e+00	1778.00
IUUC-Mdo-062478	Monodelphis domestica	81.36	0.00e+00	1919.00
IUUC-Mmu-063456	Mus musculus	80.25	0.00e+00	1642.00
IUUC-Mac-064767	Musa acuminata	38.85	9.00e-75	276.00
IUUC-Mpu-065963	Mustela putorius furo	78.57	0.00e+00	1637.00
IUUC-Mlu-067185	Myotis lucifugus	82.27	0.00e+00	1636.00
IUUC-Nle-069907	Nomascus leucogenys	82.75	0.00e+00	1637.00
IUUC-Opr-070324	Ochotona princeps	71.70	0.00e+00	959.00
IUUC-Ont-072211	Oreochromis niloticus	86.83	0.00e+00	1437.00
IUUC-Oan-073723	Ornithorhynchus anatinus	87.10	0.00e+00	1779.00
IUUC-Ocu-074707	Oryctolagus cuniculus	80.96	0.00e+00	1631.00
IUUC-Oba-075590	Oryza barthii	33.61	3.00e-103	370.00
IUUC-Ogu-078580	Oryza glumaepatula	33.47	2.00e-103	371.00
IUUC-Oin-079283	Oryza indica	38.58	7.00e-73	269.00
IUUC-Olo-080969	Oryza longistaminata	38.58	7.00e-73	269.00
IUUC-Ome-081615	Oryza meridionalis	33.61	3.00e-103	370.00
IUUC-Oni-082636	Oryza nivara	33.61	2.00e-103	370.00
IUUC-Opu-084073	Oryza punctata	38.58	1.00e-73	271.00
IUUC-Oru-084994	Oryza rufipogon	33.61	2.00e-103	370.00
IUUC-Osa-085860	Oryza sativa	41.16	1.00e-62	235.00
IUUC-Olu-087701	Ostreococcus lucimarinus	35.19	1.00e-61	231.00
IUUC-Oga-088700	Otolemur garnettii	80.74	0.00e+00	1779.00
IUUC-Oar-089787	Ovis aries	81.56	0.00e+00	1667.00
IUUC-Ptr-091620	Pan troglodytes	81.19	0.00e+00	1779.00
IUUC-Pan-092166	Papio anubis	80.92	0.00e+00	1803.00
IUUC-Psi-093992	Pelodiscus sinensis	84.31	0.00e+00	2021.00
IUUC-Pma-094328	Petromyzon marinus	84.82	0.00e+00	990.00
IUUC-Ppa-095569	Physcomitrella patens	37.34	5.00e-71	263.00
IUUC-Pfo-097342	Poecilia formosa	83.77	0.00e+00	1374.00
IUUC-Pab-098235	Pongo abelii	80.39	0.00e+00	1770.00
IUUC-Pop-098947	Populus trichocarpa	39.09	3.00e-73	271.00
IUUC-Pca-100780	Procavia capensis	81.27	0.00e+00	1342.00
IUUC-Ppe-101498	Prunus persica	37.78	2.00e-66	247.00
IUUC-Pva-103071	Pteropus vampyrus	81.06	0.00e+00	1858.00
IUUC-Sha-106736	Sarcophilus harrisii	88.55	0.00e+00	1598.00
IUUC-Smo-109420	Selaginella moellendorffii	38.01	6.00e-72	266.00
IUUC-Sit-110128	Setaria italica	37.69	1.00e-71	265.00
IUUC-Sar-113162	Sorex araneus	76.84	0.00e+00	691.00
IUUC-Sbi-114827	Sorghum bicolor	38.83	3.00e-73	271.00
IUUC-Ssc-116077	Sus scrofa	79.72	0.00e+00	1786.00
IUUC-Tgu-116872	Taeniopygia guttata	85.70	0.00e+00	1910.00
IUUC-Tru-118047	Takifugu rubripes	48.32	2.00e-100	362.00
IUUC-Tsy-119451	Tarsius syrichta	75.44	0.00e+00	1150.00
IUUC-Tca-121835	Theobroma cacao	38.48	5.00e-73	270.00
IUUC-Tvi-122536	Trichoderma virens	43.04	1.00e-15	77.00
IUUC-Tae-125906	Triticum aestivum	37.66	9.00e-67	249.00
IUUC-Tur-126284	Triticum urartu	37.91	1.00e-67	252.00
IUUC-Tbe-127772	Tupaia belangeri	72.95	0.00e+00	1151.00
IUUC-Vpa-130766	Vicugna pacos	87.14	0.00e+00	1084.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence