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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Ath-007614
UUCD1 version UUC-ArT-00639
Ensembl Protein ID AT1G49040.1
UniProt Accession Q8RXA7; Q9M9A6; Q9M9A7; SCD1_ARATH
Genbank Protein ID AAL92456.1; AAF69702.1; AAF69703.1; AEE32385.1
Protein Name DENN domain and WD repeat-containing protein SCD1; Protein STOMATAL CYTOKINESIS DEFECTIVE 1
Genbank Nucleotide ID AY082605; AC016041; AC016041; CP002684
Gene Name SCD1; At1g49040; F27J15.16/F27J15.17
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT1G49040 AT1G49040.2 AT1G49040.2
AT1G49040 AT1G49040.1 AT1G49040.1
AT1G49040 AT1G49040.3 AT1G49040.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
PINAMentha
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 9.50e-31 105.4 937 974
UBD/Beta-Prp 2.70e-53 182.0 865 1032
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrtgvllk 37
           gH + v+c++  s+ +++++++Dgt+k+WD+rt+ ++ 
   Q: 937  GHDSQVSCVKMlSGERVLTAAHDGTVKMWDVRTDMCVA 974
           8*********98889*******************9975 PP
   

   UBD/Beta-Prp
   S: 62   pdgkilvtgseDrtikvwdls..tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsG 155
           +d+ ++++gs+D ++k+wd+s   ++   tlkgh+ +v+++s+++   k+vsGs+d  + vwd +t q le  l+ghd+ v+cv++ + g  + ++
   Q: 865  EDAGFFISGSTDCLVKIWDPSlrGSELRATLKGHTGTVRAISSDR--GKIVSGSDDLSVIVWDKQTTQLLE-ELKGHDSQVSCVKMLS-GERVLTA 956
           34459*************766669*********************..***********************9.**************99.99***** PP
   S: 156  slDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfsp 232
           + D+tv++Wd++t+ ++ t      +++ sl++d++   l+++++d+  ++wd+++g+ +++l+ght++++s+r+ +
   Q: 957  AHDGTVKMWDVRTDMCVATVGR-CSSAILSLEYDDSTGILAAAGRDTVANIWDIRSGKQMHKLKGHTKWIRSIRMVE 1032
           ********************66.99************************************************9875 PP
   
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     Involved in growth and development through its role in cytokinesis and polarized cell expansion (PubMed:12874123). Required for plasma membrane internalization. May function in clathrin-mediated membrane trafficking, including plasma membrane endocytosis, essential to both cytokinesis and cell expansion (PubMed:24179130). Acts as a negative regulator of basal resistance against bacteria (PubMed:20472560).
 Involved in growth and development through its role in cytokinesis and polarized cell expansion (PubMed:12874123). Required for plasma membrane internalization. May function in clathrin-mediated membrane trafficking, including plasma membrane endocytosis, essential to both cytokinesis and cell expansion (PubMed:24179130). Acts as a negative regulator of basal resistance against bacteria (PubMed:20472560).
Protein Sequence
(Fasta)
MGRIFEYFVV CGLGPEMRTV DGDLGFHGMQ TFYLPALLDQ FPPTDQSPYP APPPQLPTCV 60
LPAGVEFHSS GFVSSDPASF PRSYPIVLTE GDGSKIFVSC IAFRDRVCED IIEAYRLPPN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ath-007614|E3,WD_repeat;UBD,Beta-Prp|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGAAAACAAA TTGCGTTCGA CCCGTAGGAT TATTTTCCCA CGAACGACTT GGCCAAAAAA 60
ACAAAGGAGG CCGAATTGAA GCAACTACTT TTCTCCATCA TCATCACCAT CGGCGAAATC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ath-007614|E3,WD_repeat;UBD,Beta-Prp|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0131--Cell cycle
KW-0132--Cell division
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0341--Growth regulation
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR005112--dDENN_dom
IPR001194--DENN_dom
IPR020472--G-protein_beta_WD-40_rep
IPR005113--uDENN_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50947--DDENN
PS50211--DENN
PS50946--UDENN
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF02141--DENN
PF03456--uDENN
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00801--dDENN
SM00799--DENN
SM00800--uDENN
SM00320--WD40
Gene Ontology

GO:0030136--C:clathrin-coated vesicle
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005886--C:plasma membrane
GO:0000911--P:cytokinesis by cell plate formation
GO:0010235--P:guard mother cell cytokinesis
GO:0009825--P:multidimensional cell growth
GO:0045824--P:negative regulation of innate immune response
GO:0040008--P:regulation of growth
KEGG ath:AT1G49040
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Atr-002593 Amborella trichopoda 72.09 0.00e+00 1655.00
IUUC-Aly-005508 Arabidopsis lyrata 98.06 0.00e+00 2269.00
IUUC-Bdi-014863 Brachypodium distachyon 69.95 0.00e+00 1655.00
IUUC-Bol-015997 Brassica oleracea 93.01 0.00e+00 2184.00
IUUC-Bra-017065 Brassica rapa 93.01 0.00e+00 2184.00
IUUC-Gma-042682 Glycine max 73.06 0.00e+00 1751.00
IUUC-Hvu-047377 Hordeum vulgare 80.06 3.00e-152 530.00
IUUC-Lpe-051109 Leersia perrieri 69.08 0.00e+00 1554.00
IUUC-Mor-057076 Magnaporthe oryzae 31.88 2.00e-28 120.00
IUUC-Mpo-057423 Magnaporthe poae 26.39 1.00e-27 117.00
IUUC-Mtr-058651 Medicago truncatula 72.84 0.00e+00 1736.00
IUUC-Mac-065420 Musa acuminata 72.14 0.00e+00 1722.00
IUUC-Ncr-068688 Neurospora crassa 26.91 5.00e-28 118.00
IUUC-Oba-075961 Oryza barthii 66.56 0.00e+00 1206.00
IUUC-Obr-076806 Oryza brachyantha 70.27 0.00e+00 1658.00
IUUC-Ogu-078716 Oryza glumaepatula 66.33 0.00e+00 1501.00
IUUC-Oin-079809 Oryza indica 58.89 0.00e+00 1256.00
IUUC-Olo-080386 Oryza longistaminata 66.09 0.00e+00 1561.00
IUUC-Ome-081107 Oryza meridionalis 67.94 0.00e+00 1576.00
IUUC-Oni-082213 Oryza nivara 64.39 0.00e+00 1445.00
IUUC-Opu-083850 Oryza punctata 64.87 0.00e+00 1420.00
IUUC-Oru-084982 Oryza rufipogon 68.20 0.00e+00 1512.00
IUUC-Osa-086141 Oryza sativa 70.35 0.00e+00 1633.00
IUUC-Olu-087744 Ostreococcus lucimarinus 31.78 1.00e-38 155.00
IUUC-Ppa-095259 Physcomitrella patens 53.10 0.00e+00 1239.00
IUUC-Pop-099233 Populus trichocarpa 76.72 0.00e+00 1803.00
IUUC-Ppe-101883 Prunus persica 73.26 0.00e+00 1419.00
IUUC-Smo-109566 Selaginella moellendorffii 57.21 0.00e+00 1362.00
IUUC-Sit-109736 Setaria italica 70.70 0.00e+00 1679.00
IUUC-Sly-111483 Solanum lycopersicum 72.59 0.00e+00 1746.00
IUUC-Sbi-113820 Sorghum bicolor 70.70 0.00e+00 1672.00
IUUC-Sre-114901 Sporisorium reilianum 30.51 2.00e-27 117.00
IUUC-Tca-121657 Theobroma cacao 76.88 0.00e+00 1807.00
IUUC-Tae-124598 Triticum aestivum 68.93 0.00e+00 1664.00
IUUC-Tur-126080 Triticum urartu 68.60 0.00e+00 1064.00
IUUC-Uma-129449 Ustilago maydis 31.11 2.00e-28 121.00
IUUC-Vvi-131550 Vitis vinifera 75.74 0.00e+00 1767.00
IUUC-Yli-134429 Yarrowia lipolytica 34.51 3.00e-33 135.00
Created Date 25-Jun-2017

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