iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-027085

Ensembl Protein ID

AAW44367

UniProt Accession

Q5KEY2; Q55R88; Q5KEY2_CRYNJ

Genbank Protein ID

AAW44367.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

AE017346

Gene Name

CNF03800

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNF03800	AAW44367	AAW44367

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.60e-66	222.0	214	576

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 3    lkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenp.......................kepkgellkslqklfeelwkskkkavsprellkalkk 79
           l Nl  tC++ +vLQ+L++ p l+ ++l+ k+++++    +                       + + g++++++ k fee+++++k+ + p ++l a+++
   Q: 214  LLNLSQTCFLSAVLQALVHNPLLKAYFLSdKHNRHVCT--NggkgllvgkpflgvengpgavgsDRERGCMCCEMDKAFEEFYNEDKSPFGPITMLYAMWH 312
           67***************************533333333..13579999999999999999999889999******************************** PP
   S: 80   eaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgke 180
           ++ e++gy qqDa+ f+   ldq++ +                         + + ++ +++ +++F g+l+s+++c +c ++s++ +p ld++l++p  +
   Q: 313  ASTELEGYGQQDAHSFFLAALDQIHAHA------------------------KGQLSSCNCIAHQTFAGSLQSSVICSKCSKTSNTVDPILDIQLDFPPPS 389
           ****************************........................568999****************************************888 PP
   S: 181  etkke....................slqdcLesftkeeele..genkyycekckkkqe..aekklklkklPevLilhLkRfsfseeqksrekinkkvefpl 257
             +                      +l  +L++f ++e++   g n y+c+ c + +   a +kl++kkl +vL+++LkRf  s++   + ki+++v fp 
   Q: 390  VPSSAssssdssafgpstngqadqlTLAGMLRKFCAPERVGdpGGNGYECSGCGGGVGvvAMRKLGVKKLAPVLSFQLKRFAHSSA-TTSVKIESHVRFPS 489
           77666889999*****************************8334688*******97655599*******************87776.7778********** PP
   S: 258  eLdlspfctspeekqke...........kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           +Ld++p++ s++++++             ++Y+L+avv H+G+l++GHY+a+v++  ++W+++dD+kVt+++ + vl    + aY+lfY +
   Q: 490  TLDMRPYVDSSSSSKSGndrkekelpdsLYIYDLFAVVTHEGKLDNGHYWADVRD-GEEWWHCDDDKVTPTSLSAVLA---QRAYMLFYVK 576
           *********9666655588899999999***************************.777*******************...9*******87 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MATPQSRIFD RTDTSICPHL SALLSIPSAS SRNPGTSGAK GNTLGFPPGS KGAEIEKRFV 60
DVVKWGALPQ GVKRRKTMSP GCHTCKTPLS RPWACLTCPY VGCMPLVGKG ANEKDCMKRH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTGCTGCT CATAACCTGG ATCTGTGACT ACCCTCAGTA ACAGTCGCAG CTTGGTTATA 60
CATCGAGACG GCATATAAAT CCCACCTGGC GCGATGGCGA CCCCTCAATC CCGCATATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cne:CNF03800

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000393	Aegilops tauschii	30.18	2.00e-42	165.00
IUUC-Aml-001343	Ailuropoda melanoleuca	34.09	1.00e-68	251.00
IUUC-Atr-002653	Amborella trichopoda	31.43	1.00e-66	245.00
IUUC-Apl-003433	Anas platyrhynchos	34.35	8.00e-66	242.00
IUUC-Aca-005347	Anolis carolinensis	33.75	6.00e-66	243.00
IUUC-Aly-006565	Arabidopsis lyrata	31.36	2.00e-50	191.00
IUUC-Ath-007536	Arabidopsis thaliana	31.57	2.00e-51	194.00
IUUC-Ago-007811	Ashbya gossypii	25.91	1.00e-37	149.00
IUUC-Acl-008124	Aspergillus clavatus	33.13	1.00e-61	228.00
IUUC-Afl-008464	Aspergillus flavus	33.71	9.00e-56	208.00
IUUC-Afu-008912	Aspergillus fumigatus	33.33	2.00e-63	234.00
IUUC-Ani-009168	Aspergillus nidulans	31.68	1.00e-58	218.00
IUUC-Ang-009694	Aspergillus niger	32.41	2.00e-61	228.00
IUUC-Aor-010035	Aspergillus oryzae	37.09	1.00e-41	160.00
IUUC-Ate-010382	Aspergillus terreus	33.93	2.00e-56	210.00
IUUC-Ame-011253	Astyanax mexicanus	32.32	9.00e-60	222.00
IUUC-Bgr-012150	Blumeria graminis	28.08	2.00e-44	171.00
IUUC-Bta-013303	Bos taurus	33.46	1.00e-67	248.00
IUUC-Bci-013604	Botrytis cinerea	28.16	2.00e-49	188.00
IUUC-Bdi-014171	Brachypodium distachyon	31.24	1.00e-55	209.00
IUUC-Bol-016509	Brassica oleracea	30.74	6.00e-51	194.00
IUUC-Bra-016962	Brassica rapa	29.75	2.00e-47	181.00
IUUC-Cja-019283	Callithrix jacchus	33.97	1.00e-61	228.00
IUUC-Cfa-021239	Canis familiaris	33.59	2.00e-67	247.00
IUUC-Cpo-022354	Cavia porcellus	33.46	6.00e-69	253.00
IUUC-Csa-023145	Chlorocebus sabaeus	33.84	7.00e-68	249.00
IUUC-Cin-025109	Ciona intestinalis	28.19	3.00e-40	157.00
IUUC-Csv-026214	Ciona savignyi	29.24	7.00e-55	206.00
IUUC-Cgl-026457	Colletotrichum gloeosporioides	28.18	3.00e-48	184.00
IUUC-Cme-027115	Cyanidioschyzon merolae	28.66	3.00e-24	105.00
IUUC-Dre-027433	Danio rerio	33.14	8.00e-66	242.00
IUUC-Dno-030095	Dasypus novemcinctus	33.46	2.00e-66	244.00
IUUC-Dse-031415	Dothistroma septosporum	29.12	2.00e-56	211.00
IUUC-Dme-032074	Drosophila melanogaster	29.84	8.00e-59	219.00
IUUC-Ete-032627	Echinops telfairi	25.98	4.00e-27	114.00
IUUC-Eca-033736	Equus caballus	33.46	1.00e-65	241.00
IUUC-Fca-035861	Felis catus	33.52	3.00e-67	247.00
IUUC-Fal-037645	Ficedula albicollis	34.16	3.00e-64	237.00
IUUC-Fox-038046	Fusarium oxysporum	29.35	5.00e-51	193.00
IUUC-Fso-038321	Fusarium solani	30.26	8.00e-49	185.00
IUUC-Gmo-038474	Gadus morhua	36.57	5.00e-44	170.00
IUUC-Ggr-040044	Gaeumannomyces graminis	29.41	4.00e-48	183.00
IUUC-Gga-040624	Gallus gallus	34.08	5.00e-67	246.00
IUUC-Gac-042197	Gasterosteus aculeatus	32.58	2.00e-63	234.00
IUUC-Gma-042897	Glycine max	31.96	2.00e-66	244.00
IUUC-Ggo-044409	Gorilla gorilla	33.84	6.00e-68	249.00
IUUC-Hsa-046521	Homo sapiens	33.84	6.00e-68	249.00
IUUC-Hvu-047739	Hordeum vulgare	31.75	8.00e-53	198.00
IUUC-Itr-048375	Ictidomys tridecemlineatus	33.90	6.00e-68	249.00
IUUC-Kpa-049135	Komagataella pastoris	30.50	1.00e-62	232.00
IUUC-Lch-050537	Latimeria chalumnae	33.52	2.00e-69	254.00
IUUC-Lpe-050969	Leersia perrieri	31.00	8.00e-53	199.00
IUUC-Loc-052765	Lepisosteus oculatus	31.86	9.00e-52	196.00
IUUC-Lma-053105	Leptosphaeria maculans	30.06	3.00e-53	201.00
IUUC-Laf-053571	Loxodonta africana	33.46	3.00e-67	247.00
IUUC-Mcc-055166	Macaca mulatta	33.84	7.00e-68	249.00
IUUC-Mor-057103	Magnaporthe oryzae	28.02	8.00e-49	186.00
IUUC-Mpo-057621	Magnaporthe poae	30.59	1.00e-52	199.00
IUUC-Mtr-057769	Medicago truncatula	32.01	3.00e-65	240.00
IUUC-Mla-059185	Melampsora laricipopulina	26.74	2.00e-42	164.00
IUUC-Mga-059709	Meleagris gallopavo	34.35	8.00e-66	242.00
IUUC-Mvi-060530	Microbotryum violaceum	29.54	2.00e-54	204.00
IUUC-Mmr-060988	Microcebus murinus	34.27	1.00e-67	248.00
IUUC-Mdo-063065	Monodelphis domestica	33.89	5.00e-69	253.00
IUUC-Mmu-063829	Mus musculus	33.90	2.00e-67	248.00
IUUC-Mac-065419	Musa acuminata	29.85	2.00e-55	208.00
IUUC-Mpu-066687	Mustela putorius furo	33.40	3.00e-66	244.00
IUUC-Mlu-067330	Myotis lucifugus	32.04	2.00e-64	238.00
IUUC-Nfi-068423	Neosartorya fischeri	33.74	5.00e-64	236.00
IUUC-Ncr-068809	Neurospora crassa	27.98	6.00e-47	179.00
IUUC-Nle-069859	Nomascus leucogenys	30.64	7.00e-62	229.00
IUUC-Opr-070469	Ochotona princeps	39.34	1.00e-33	135.00
IUUC-Ont-071961	Oreochromis niloticus	33.27	2.00e-65	241.00
IUUC-Oan-073565	Ornithorhynchus anatinus	31.73	8.00e-60	222.00
IUUC-Ocu-074365	Oryctolagus cuniculus	31.31	4.00e-62	230.00
IUUC-Oba-075688	Oryza barthii	30.44	1.00e-51	195.00
IUUC-Obr-076652	Oryza brachyantha	33.42	8.00e-52	195.00
IUUC-Ogl-077910	Oryza glaberrima	31.04	4.00e-55	207.00
IUUC-Ogu-078479	Oryza glumaepatula	30.42	1.00e-54	205.00
IUUC-Oin-079697	Oryza indica	32.91	6.00e-51	192.00
IUUC-Olo-080811	Oryza longistaminata	32.99	5.00e-32	129.00
IUUC-Ome-081706	Oryza meridionalis	31.11	2.00e-54	205.00
IUUC-Oni-083070	Oryza nivara	30.83	2.00e-54	204.00
IUUC-Opu-083605	Oryza punctata	31.93	1.00e-46	178.00
IUUC-Oru-084522	Oryza rufipogon	31.04	4.00e-55	207.00
IUUC-Osa-085351	Oryza sativa	31.22	7.00e-51	193.00
IUUC-Ola-086743	Oryzias latipes	36.45	2.00e-60	224.00
IUUC-Olu-087695	Ostreococcus lucimarinus	27.65	1.00e-31	128.00
IUUC-Oga-089131	Otolemur garnettii	33.52	7.00e-67	246.00
IUUC-Oar-089319	Ovis aries	33.46	2.00e-66	244.00
IUUC-Ptr-090783	Pan troglodytes	33.85	5.00e-67	246.00
IUUC-Pan-092927	Papio anubis	33.84	6.00e-68	249.00
IUUC-Psi-093670	Pelodiscus sinensis	34.35	7.00e-66	242.00
IUUC-Pma-094323	Petromyzon marinus	30.22	1.00e-49	189.00
IUUC-Pno-095141	Phaeosphaeria nodorum	26.76	2.00e-43	168.00
IUUC-Ppa-095413	Physcomitrella patens	29.61	1.00e-55	208.00
IUUC-Pfo-096462	Poecilia formosa	33.40	5.00e-68	249.00
IUUC-Pab-097612	Pongo abelii	33.84	8.00e-68	249.00
IUUC-Pop-099558	Populus trichocarpa	32.42	4.00e-66	243.00
IUUC-Pca-100329	Procavia capensis	31.68	7.00e-64	236.00
IUUC-Ppe-102020	Prunus persica	32.73	3.00e-67	247.00
IUUC-Pva-102721	Pteropus vampyrus	30.74	1.00e-58	219.00
IUUC-Pgr-103657	Puccinia graminis	25.13	2.00e-38	151.00
IUUC-Pte-104340	Pyrenophora teres	29.06	2.00e-48	184.00
IUUC-Pyt-104782	Pyrenophora triticirepentis	30.26	3.00e-56	211.00
IUUC-Rno-105247	Rattus norvegicus	33.27	2.00e-67	248.00
IUUC-Sce-106247	Saccharomyces cerevisiae	28.10	1.00e-38	151.00
IUUC-Sja-107656	Schizosaccharomyces japonicus	30.59	1.00e-56	211.00
IUUC-Spo-108226	Schizosaccharomyces pombe	30.92	6.00e-55	206.00
IUUC-Ssl-108531	Sclerotinia sclerotiorum	27.09	3.00e-45	174.00
IUUC-Smo-109310	Selaginella moellendorffii	31.70	2.00e-64	238.00
IUUC-Sit-109716	Setaria italica	31.78	9.00e-56	209.00
IUUC-Sly-111077	Solanum lycopersicum	31.43	5.00e-61	226.00
IUUC-Stu-112203	Solanum tuberosum	31.41	3.00e-57	213.00
IUUC-Sar-113174	Sorex araneus	31.37	1.00e-58	218.00
IUUC-Sbi-114205	Sorghum bicolor	31.51	4.00e-57	213.00
IUUC-Sre-115195	Sporisorium reilianum	36.15	5.00e-33	134.00
IUUC-Ssc-115315	Sus scrofa	31.54	7.00e-65	239.00
IUUC-Tgu-116938	Taeniopygia guttata	34.23	5.00e-67	246.00
IUUC-Tru-117622	Takifugu rubripes	33.82	6.00e-69	253.00
IUUC-Tsy-119413	Tarsius syrichta	31.05	1.00e-60	225.00
IUUC-Tni-120119	Tetraodon nigroviridis	33.83	2.00e-69	254.00
IUUC-Tca-121716	Theobroma cacao	31.04	1.00e-58	219.00
IUUC-Tre-122139	Trichoderma reesei	29.27	7.00e-46	176.00
IUUC-Tvi-122599	Trichoderma virens	28.65	1.00e-46	178.00
IUUC-Tae-125608	Triticum aestivum	29.92	1.00e-61	229.00
IUUC-Tme-127115	Tuber melanosporum	33.01	8.00e-68	249.00
IUUC-Tbe-128084	Tupaia belangeri	27.39	4.00e-29	121.00
IUUC-Ttr-129006	Tursiops truncatus	31.30	5.00e-61	226.00
IUUC-Uma-129455	Ustilago maydis	38.08	8.00e-34	137.00
IUUC-Vda-129829	Verticillium dahliae	32.91	1.00e-33	134.00
IUUC-Vpa-130706	Vicugna pacos	25.50	3.00e-27	115.00
IUUC-Vvi-131477	Vitis vinifera	29.85	1.00e-51	195.00
IUUC-Xtr-132444	Xenopus tropicalis	34.51	6.00e-69	253.00
IUUC-Xma-133514	Xiphophorus maculatus	33.77	4.00e-70	256.00
IUUC-Yli-134357	Yarrowia lipolytica	30.48	2.00e-46	178.00
IUUC-Zma-134945	Zea mays	30.71	7.00e-55	206.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence