iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000014222.4	ENSCAFT00000047620.2	ENSCAFP00000040335.1
ENSCAFG00000014222.4	ENSCAFT00000022596.3	ENSCAFP00000020981.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.50e-14	52.1	235	263

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+ ++t++a+ +d  l+++Gs  +t++++D
   Q: 235  HEHPITSVAWaPDgELFAVGS-FHTLRLCD 263
           99*********9978888887.689*9999 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MRLKISLLKE PKRLLNTVTH QELVSCVGWT TAEELYSCSD DHQIVKWNLL TGETSQIVKL 60
PDDIYPIDLH WFPKSLGIKK QTQAESFVLT SSDGKFHLIS KLGRVEKSVE AHCGAVLAGR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGACTGA AGATATCTCT TTTAAAAGAA CCAAAACATA TCCTTTTAAT GCTTATAAAC 60
CTTATTGTGA TCATCTTACA AGAGTATTGT TAAAGTTTTC TATTTTGTAT TCTAGTTAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0030992--C:intraciliary transport particle B
GO:0060349--P:bone morphogenesis
GO:0002062--P:chondrocyte differentiation
GO:0060271--P:cilium assembly
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:1905515--P:non-motile cilium assembly
GO:0001649--P:osteoblast differentiation
GO:0045880--P:positive regulation of smoothened signaling pathway
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001564	Ailuropoda melanoleuca	96.89	0.00e+00	902.00
IUUC-Apl-003721	Anas platyrhynchos	85.66	0.00e+00	1386.00
IUUC-Aca-004488	Anolis carolinensis	86.07	0.00e+00	1397.00
IUUC-Ame-011402	Astyanax mexicanus	80.47	0.00e+00	817.00
IUUC-Bta-013037	Bos taurus	87.71	0.00e+00	1344.00
IUUC-Cel-018360	Caenorhabditis elegans	40.94	0.00e+00	664.00
IUUC-Cja-019076	Callithrix jacchus	94.51	0.00e+00	1223.00
IUUC-Cpo-021333	Cavia porcellus	86.14	0.00e+00	1311.00
IUUC-Cre-022899	Chlamydomonas reinhardtii	47.63	0.00e+00	681.00
IUUC-Csa-023699	Chlorocebus sabaeus	96.61	0.00e+00	1524.00
IUUC-Cho-024904	Choloepus hoffmanni	87.37	0.00e+00	832.00
IUUC-Cin-025399	Ciona intestinalis	57.42	0.00e+00	963.00
IUUC-Csv-026186	Ciona savignyi	55.47	0.00e+00	930.00
IUUC-Dre-028276	Danio rerio	74.94	0.00e+00	1273.00
IUUC-Dno-029824	Dasypus novemcinctus	98.04	0.00e+00	1562.00
IUUC-Dor-031141	Dipodomys ordii	91.58	0.00e+00	1436.00
IUUC-Dme-031620	Drosophila melanogaster	35.69	2.00e-144	506.00
IUUC-Eca-033339	Equus caballus	95.41	0.00e+00	1506.00
IUUC-Eeu-034909	Erinaceus europaeus	95.94	0.00e+00	1014.00
IUUC-Fca-035780	Felis catus	98.30	0.00e+00	1519.00
IUUC-Fal-037447	Ficedula albicollis	79.19	0.00e+00	1271.00
IUUC-Gmo-038657	Gadus morhua	61.32	0.00e+00	833.00
IUUC-Gga-040689	Gallus gallus	85.79	0.00e+00	1382.00
IUUC-Gac-041586	Gasterosteus aculeatus	72.50	0.00e+00	1020.00
IUUC-Hsa-047005	Homo sapiens	95.79	0.00e+00	1539.00
IUUC-Itr-048757	Ictidomys tridecemlineatus	97.86	0.00e+00	1125.00
IUUC-Lch-050459	Latimeria chalumnae	81.66	0.00e+00	1328.00
IUUC-Loc-052774	Lepisosteus oculatus	78.90	0.00e+00	1070.00
IUUC-Laf-053765	Loxodonta africana	96.11	0.00e+00	1488.00
IUUC-Mcc-055052	Macaca mulatta	96.61	0.00e+00	1524.00
IUUC-Meu-056368	Macropus eugenii	81.82	0.00e+00	1273.00
IUUC-Mga-059488	Meleagris gallopavo	85.92	0.00e+00	1389.00
IUUC-Mmr-061527	Microcebus murinus	96.23	0.00e+00	1513.00
IUUC-Mdo-062850	Monodelphis domestica	95.25	0.00e+00	1227.00
IUUC-Mmu-063117	Mus musculus	95.41	0.00e+00	1509.00
IUUC-Mpu-066550	Mustela putorius furo	98.55	0.00e+00	1420.00
IUUC-Mlu-067772	Myotis lucifugus	92.58	0.00e+00	1420.00
IUUC-Nle-069215	Nomascus leucogenys	94.89	0.00e+00	1524.00
IUUC-Opr-070725	Ochotona princeps	74.35	0.00e+00	1119.00
IUUC-Ont-072147	Oreochromis niloticus	73.09	0.00e+00	1264.00
IUUC-Oan-073176	Ornithorhynchus anatinus	86.29	4.00e-62	229.00
IUUC-Ocu-073896	Oryctolagus cuniculus	96.03	0.00e+00	1231.00
IUUC-Ola-086767	Oryzias latipes	68.09	0.00e+00	962.00
IUUC-Oga-088113	Otolemur garnettii	96.75	0.00e+00	1548.00
IUUC-Oar-089683	Ovis aries	92.87	0.00e+00	1471.00
IUUC-Ptr-091563	Pan troglodytes	96.36	0.00e+00	1538.00
IUUC-Pan-092042	Papio anubis	96.61	0.00e+00	1524.00
IUUC-Psi-093306	Pelodiscus sinensis	87.66	0.00e+00	1449.00
IUUC-Ppa-095694	Physcomitrella patens	44.17	0.00e+00	719.00
IUUC-Pfo-096800	Poecilia formosa	72.58	0.00e+00	1247.00
IUUC-Pab-098356	Pongo abelii	95.66	0.00e+00	1536.00
IUUC-Pva-102246	Pteropus vampyrus	91.89	0.00e+00	1427.00
IUUC-Rno-105195	Rattus norvegicus	95.15	0.00e+00	1512.00
IUUC-Sha-107056	Sarcophilus harrisii	94.81	0.00e+00	1498.00
IUUC-Smo-109240	Selaginella moellendorffii	43.73	2.00e-175	608.00
IUUC-Sar-113301	Sorex araneus	87.76	6.00e-152	531.00
IUUC-Ssc-116040	Sus scrofa	96.48	3.00e-148	517.00
IUUC-Tgu-117127	Taeniopygia guttata	81.27	0.00e+00	1324.00
IUUC-Tru-118663	Takifugu rubripes	70.52	0.00e+00	1200.00
IUUC-Tsy-119207	Tarsius syrichta	84.31	0.00e+00	1314.00
IUUC-Tni-120705	Tetraodon nigroviridis	69.48	0.00e+00	1191.00
IUUC-Tbe-127434	Tupaia belangeri	87.41	0.00e+00	958.00
IUUC-Ttr-128937	Tursiops truncatus	96.94	0.00e+00	1537.00
IUUC-Vpa-130518	Vicugna pacos	91.33	0.00e+00	1412.00
IUUC-Xtr-131879	Xenopus tropicalis	78.36	0.00e+00	1278.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence