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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Spo-108160
Ensembl Protein ID SPAC4F8.12c.1:pep
UniProt Accession O14187; SPP42_SCHPO
Genbank Protein ID CAB11062.1
Protein Name Pre-mRNA-splicing factor spp42; Complexed with cdc5 protein 6
Genbank Nucleotide ID CU329670
Gene Name spp42; cwf6; SPAC4F8.12c
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPAC4F8.12c SPAC4F8.12c.1 SPAC4F8.12c.1:pep
Annotation
mRNA Expression
GEO
Protein-protein Interaction
iRefIndexMentha
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
dbPAFdbPTMUniProt
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Jab_MPN 62.05 0.00e+00 2982.00 IUUC-Sce-106157
UBD/Jab_MPN 61.96 0.00e+00 2979.00 IUUC-Ots-000011
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures (By similarity). Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region.
 Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures (By similarity). Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region.
Protein Sequence
(Fasta)
MASLPPGNPP PPPPPPGFEP PSQPPPPPPP GYVKKRKNKT PAQSGNLEKQ LNERARKWRA 60
SQKSKFGVKR KQGYVQTEKA DLPPEHLRKI MKDRGDMSSR KFRADKRSYL GALKYLPHAV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108160|UBD,Jab_MPN|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ACAAAGTAAT ATTCACTACC ACAATTCAGC TGACAAATAC CATTACCTAA ATGGCGTCGT 60
TACCACCGGG GAATCCTCCT CCACCGCCTC CTCCGCCTGG ATTTGAGCCT CCTTCACAGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108160|UBD,Jab_MPN|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0694--RNA-binding
KW-0747--Spliceosome
Interpro

IPR000555--JAMM/MPN+_dom
IPR012591--PRO8NT
IPR012592--PROCN
IPR012984--PROCT
IPR027652--PRP8
IPR021983--PRP8_domainIV
IPR019581--Prp8_U5-snRNA-bd
IPR019580--Prp8_U6-snRNA-bd
IPR012337--RNaseH-like_dom
IPR019582--RRM_spliceosomal_PrP8
Pfam

PF01398--JAB
PF08082--PRO8NT
PF08083--PROCN
PF08084--PROCT
PF12134--PRP8_domainIV
PF10598--RRM_4
PF10597--U5_2-snRNA_bdg
PF10596--U6-snRNA_bdg
SMART

SM00232--JAB_MPN
Gene Ontology

GO:0071014--C:post-mRNA release spliceosomal complex
GO:0000974--C:Prp19 complex
GO:0005681--C:spliceosomal complex
GO:0046540--C:U4/U6 x U5 tri-snRNP complex
GO:0005682--C:U5 snRNP
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0030623--F:U5 snRNA binding
GO:0017070--F:U6 snRNA binding
GO:0000393--P:spliceosomal conformational changes to generate catalytic conformation
KEGG spo:SPAC4F8.12c
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001091 Aegilops tauschii 73.78 0.00e+00 3472.00
IUUC-Aml-002261 Ailuropoda melanoleuca 73.84 0.00e+00 3502.00
IUUC-Atr-002524 Amborella trichopoda 73.04 0.00e+00 3500.00
IUUC-Apl-004039 Anas platyrhynchos 74.32 0.00e+00 3423.00
IUUC-Aca-005394 Anolis carolinensis 75.91 0.00e+00 2935.00
IUUC-Aly-005909 Arabidopsis lyrata 72.81 0.00e+00 3489.00
IUUC-Ath-007237 Arabidopsis thaliana 73.54 0.00e+00 3501.00
IUUC-Ago-007815 Ashbya gossypii 63.27 0.00e+00 3069.00
IUUC-Acl-008111 Aspergillus clavatus 73.09 0.00e+00 3543.00
IUUC-Afl-008609 Aspergillus flavus 73.86 0.00e+00 2181.00
IUUC-Afu-009078 Aspergillus fumigatus 73.94 0.00e+00 2337.00
IUUC-Ani-009297 Aspergillus nidulans 73.34 0.00e+00 2306.00
IUUC-Ang-009749 Aspergillus niger 73.29 0.00e+00 3566.00
IUUC-Aor-010106 Aspergillus oryzae 73.20 0.00e+00 3550.00
IUUC-Ate-010566 Aspergillus terreus 73.30 0.00e+00 3553.00
IUUC-Ame-011416 Astyanax mexicanus 73.84 0.00e+00 3538.00
IUUC-Bgr-012078 Blumeria graminis 71.06 0.00e+00 2222.00
IUUC-Bta-013532 Bos taurus 73.84 0.00e+00 3502.00
IUUC-Bci-013914 Botrytis cinerea 73.29 0.00e+00 2315.00
IUUC-Bdi-014349 Brachypodium distachyon 73.42 0.00e+00 3500.00
IUUC-Bol-015707 Brassica oleracea 73.29 0.00e+00 3490.00
IUUC-Bra-017086 Brassica rapa 72.56 0.00e+00 3464.00
IUUC-Cel-018508 Caenorhabditis elegans 73.10 0.00e+00 3481.00
IUUC-Cja-019483 Callithrix jacchus 73.84 0.00e+00 3502.00
IUUC-Cfa-021018 Canis familiaris 73.84 0.00e+00 3502.00
IUUC-Cpo-022159 Cavia porcellus 73.84 0.00e+00 3502.00
IUUC-Cre-022998 Chlamydomonas reinhardtii 73.12 0.00e+00 3427.00
IUUC-Csa-023885 Chlorocebus sabaeus 73.84 0.00e+00 3502.00
IUUC-Cho-024639 Choloepus hoffmanni 78.30 0.00e+00 2178.00
IUUC-Cin-025356 Ciona intestinalis 60.42 6.00e-152 528.00
IUUC-Csv-025880 Ciona savignyi 72.68 0.00e+00 3470.00
IUUC-Cgl-026713 Colletotrichum gloeosporioides 71.09 0.00e+00 3437.00
IUUC-Cne-026874 Cryptococcus neoformans 72.56 0.00e+00 2130.00
IUUC-Cme-027252 Cyanidioschyzon merolae 34.31 0.00e+00 998.00
IUUC-Dre-027996 Danio rerio 73.79 0.00e+00 3536.00
IUUC-Dno-029708 Dasypus novemcinctus 76.14 0.00e+00 3348.00
IUUC-Dor-030119 Dipodomys ordii 71.27 0.00e+00 3164.00
IUUC-Dse-031333 Dothistroma septosporum 71.66 0.00e+00 3446.00
IUUC-Dme-031908 Drosophila melanogaster 74.35 0.00e+00 3505.00
IUUC-Ete-032766 Echinops telfairi 71.16 0.00e+00 3336.00
IUUC-Eca-034109 Equus caballus 73.84 0.00e+00 3502.00
IUUC-Eeu-035094 Erinaceus europaeus 77.48 0.00e+00 1869.00
IUUC-Fca-035567 Felis catus 77.46 0.00e+00 3026.00
IUUC-Fal-036613 Ficedula albicollis 73.92 0.00e+00 3509.00
IUUC-Fox-037855 Fusarium oxysporum 72.81 0.00e+00 3518.00
IUUC-Fso-038078 Fusarium solani 72.52 0.00e+00 3507.00
IUUC-Gmo-038986 Gadus morhua 72.34 0.00e+00 3471.00
IUUC-Ggr-039855 Gaeumannomyces graminis 71.40 0.00e+00 3455.00
IUUC-Gga-040719 Gallus gallus 73.92 0.00e+00 3510.00
IUUC-Gac-042502 Gasterosteus aculeatus 73.53 0.00e+00 3522.00
IUUC-Gma-043317 Glycine max 73.23 0.00e+00 3469.00
IUUC-Ggo-045622 Gorilla gorilla 70.51 0.00e+00 3269.00
IUUC-Hsa-046060 Homo sapiens 73.84 0.00e+00 3502.00
IUUC-Hvu-047251 Hordeum vulgare 75.54 0.00e+00 3338.00
IUUC-Itr-048517 Ictidomys tridecemlineatus 72.05 0.00e+00 1778.00
IUUC-Kpa-049289 Komagataella pastoris 66.19 0.00e+00 3194.00
IUUC-Lch-049690 Latimeria chalumnae 73.63 0.00e+00 3298.00
IUUC-Lpe-050868 Leersia perrieri 72.52 0.00e+00 3484.00
IUUC-Loc-052365 Lepisosteus oculatus 73.48 0.00e+00 3512.00
IUUC-Lma-053043 Leptosphaeria maculans 72.29 0.00e+00 3560.00
IUUC-Laf-053582 Loxodonta africana 73.84 0.00e+00 3502.00
IUUC-Mcc-055024 Macaca mulatta 73.84 0.00e+00 3502.00
IUUC-Meu-056637 Macropus eugenii 72.45 0.00e+00 3408.00
IUUC-Mor-057244 Magnaporthe oryzae 71.79 0.00e+00 3437.00
IUUC-Mpo-057580 Magnaporthe poae 71.40 0.00e+00 3451.00
IUUC-Mtr-058326 Medicago truncatula 72.97 0.00e+00 3492.00
IUUC-Mla-059121 Melampsora laricipopulina 71.58 0.00e+00 3339.00
IUUC-Mga-059789 Meleagris gallopavo 73.92 0.00e+00 3510.00
IUUC-Mvi-060563 Microbotryum violaceum 71.44 0.00e+00 3382.00
IUUC-Mmr-060880 Microcebus murinus 73.00 0.00e+00 3447.00
IUUC-Mdo-062237 Monodelphis domestica 73.79 0.00e+00 3503.00
IUUC-Mmu-064177 Mus musculus 73.84 0.00e+00 3505.00
IUUC-Mac-065558 Musa acuminata 72.43 0.00e+00 3349.00
IUUC-Mpu-066903 Mustela putorius furo 73.84 0.00e+00 3502.00
IUUC-Mlu-067424 Myotis lucifugus 73.74 0.00e+00 3495.00
IUUC-Nfi-068265 Neosartorya fischeri 73.83 0.00e+00 2335.00
IUUC-Ncr-068963 Neurospora crassa 72.45 0.00e+00 3505.00
IUUC-Nle-069111 Nomascus leucogenys 76.03 0.00e+00 2530.00
IUUC-Opr-070706 Ochotona princeps 73.02 0.00e+00 3439.00
IUUC-Ont-071405 Oreochromis niloticus 73.97 0.00e+00 3531.00
IUUC-Oan-073481 Ornithorhynchus anatinus 76.28 0.00e+00 1719.00
IUUC-Ocu-074231 Oryctolagus cuniculus 73.84 0.00e+00 3502.00
IUUC-Oba-075452 Oryza barthii 73.86 0.00e+00 3462.00
IUUC-Obr-076377 Oryza brachyantha 73.91 0.00e+00 3457.00
IUUC-Ogl-077666 Oryza glaberrima 73.53 0.00e+00 3495.00
IUUC-Ogu-078187 Oryza glumaepatula 73.91 0.00e+00 3461.00
IUUC-Oin-079234 Oryza indica 73.82 0.00e+00 3458.00
IUUC-Olo-080543 Oryza longistaminata 73.91 0.00e+00 3459.00
IUUC-Ome-081541 Oryza meridionalis 72.95 0.00e+00 3464.00
IUUC-Oni-082712 Oryza nivara 76.54 0.00e+00 2868.00
IUUC-Opu-083904 Oryza punctata 73.29 0.00e+00 3487.00
IUUC-Oru-084749 Oryza rufipogon 73.36 0.00e+00 3501.00
IUUC-Osa-085504 Oryza sativa 74.18 0.00e+00 1759.00
IUUC-Ola-087464 Oryzias latipes 74.04 0.00e+00 3352.00
IUUC-Olu-087705 Ostreococcus lucimarinus 72.59 0.00e+00 3487.00
IUUC-Oga-087910 Otolemur garnettii 91.47 2.00e-69 251.00
IUUC-Oar-089892 Ovis aries 73.74 0.00e+00 3496.00
IUUC-Ptr-090562 Pan troglodytes 85.16 0.00e+00 825.00
IUUC-Pan-092555 Papio anubis 74.28 0.00e+00 3473.00
IUUC-Psi-094049 Pelodiscus sinensis 73.79 0.00e+00 3504.00
IUUC-Pma-094240 Petromyzon marinus 72.61 0.00e+00 3331.00
IUUC-Pno-095146 Phaeosphaeria nodorum 70.44 0.00e+00 3432.00
IUUC-Ppa-095776 Physcomitrella patens 73.21 0.00e+00 3501.00
IUUC-Pfo-097177 Poecilia formosa 73.71 0.00e+00 3524.00
IUUC-Pab-097961 Pongo abelii 73.84 0.00e+00 3502.00
IUUC-Pop-099731 Populus trichocarpa 72.74 0.00e+00 3494.00
IUUC-Pca-100655 Procavia capensis 77.39 0.00e+00 1343.00
IUUC-Ppe-101199 Prunus persica 71.71 0.00e+00 3410.00
IUUC-Pva-103175 Pteropus vampyrus 79.19 0.00e+00 2922.00
IUUC-Pgr-103467 Puccinia graminis 71.27 0.00e+00 3358.00
IUUC-Ptt-103770 Puccinia triticina 74.06 0.00e+00 2522.00
IUUC-Pte-104210 Pyrenophora teres 71.80 0.00e+00 3519.00
IUUC-Pyt-104572 Pyrenophora triticirepentis 72.57 0.00e+00 2299.00
IUUC-Rno-105997 Rattus norvegicus 73.84 0.00e+00 3505.00
IUUC-Sce-106157 Saccharomyces cerevisiae 62.29 0.00e+00 3003.00
IUUC-Sha-107355 Sarcophilus harrisii 73.79 0.00e+00 3505.00
IUUC-Sja-107760 Schizosaccharomyces japonicus 89.71 0.00e+00 4253.00
IUUC-Ssl-108519 Sclerotinia sclerotiorum 73.13 0.00e+00 2305.00
IUUC-Smo-109278 Selaginella moellendorffii 73.18 0.00e+00 3495.00
IUUC-Sit-110777 Setaria italica 73.39 0.00e+00 3507.00
IUUC-Sly-110889 Solanum lycopersicum 73.48 0.00e+00 3507.00
IUUC-Stu-112016 Solanum tuberosum 73.40 0.00e+00 3507.00
IUUC-Sar-113245 Sorex araneus 79.11 0.00e+00 1920.00
IUUC-Sbi-114423 Sorghum bicolor 74.09 0.00e+00 1571.00
IUUC-Sre-115077 Sporisorium reilianum 65.02 0.00e+00 3102.00
IUUC-Ssc-116211 Sus scrofa 74.04 0.00e+00 3391.00
IUUC-Tgu-116697 Taeniopygia guttata 73.92 0.00e+00 3509.00
IUUC-Tru-117984 Takifugu rubripes 73.66 0.00e+00 3528.00
IUUC-Tsy-118893 Tarsius syrichta 74.65 0.00e+00 1219.00
IUUC-Tni-120620 Tetraodon nigroviridis 75.85 0.00e+00 2670.00
IUUC-Tca-121331 Theobroma cacao 73.19 0.00e+00 3482.00
IUUC-Tre-122031 Trichoderma reesei 72.77 0.00e+00 3508.00
IUUC-Tvi-122603 Trichoderma virens 72.38 0.00e+00 3495.00
IUUC-Tae-125167 Triticum aestivum 73.44 0.00e+00 3511.00
IUUC-Tur-126772 Triticum urartu 73.74 0.00e+00 3476.00
IUUC-Tme-126899 Tuber melanosporum 73.05 0.00e+00 3544.00
IUUC-Tbe-127364 Tupaia belangeri 81.35 0.00e+00 2459.00
IUUC-Ttr-129009 Tursiops truncatus 73.36 0.00e+00 3474.00
IUUC-Vda-130015 Verticillium dahliae 71.98 0.00e+00 2286.00
IUUC-Vpa-130769 Vicugna pacos 81.80 0.00e+00 991.00
IUUC-Vvi-131030 Vitis vinifera 73.00 0.00e+00 3475.00
IUUC-Xtr-132067 Xenopus tropicalis 73.63 0.00e+00 3506.00
IUUC-Xma-134252 Xiphophorus maculatus 73.62 0.00e+00 3523.00
IUUC-Yli-134434 Yarrowia lipolytica 65.46 0.00e+00 3130.00
IUUC-Zma-134994 Zea mays 73.53 0.00e+00 3502.00
Created Date 25-Jun-2017

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