iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004847

Ensembl Protein ID

ENSACAP00000011651.3

UniProt Accession

H9GI83; H9GI83_ANOCA

Protein Name

Uncharacterized protein

Gene Name

VCP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000011733.3	ENSACAT00000011891.3	ENSACAP00000011651.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Other/Other	97.03	0.00e+00	1481.00	IUUC-Hsa-046162
UBD/Other/Other	70.23	0.00e+00	1097.00	IUUC-Sce-106244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MASGPDSKSD DLSTAILKQK NRPNRLIVDE AINEDNSVVS LSQAKMDELQ LFRGDTVLLK 60
GKKRREAVCI VLSDDTCSDE KIRMNRVVRN NLRVRLGDVI SIQPCPDVKY GKRIHVLPID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTGGAATA ATTATAATGT TTTGGTATAT AATATTTGTC ATAACATGTA TATATTATGT 60
ACATATGTAG ATTTCCCATC CTGTTACTTC ATATACATTT AAAATTTTGC ATGTTAATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR003593--AAA+_ATPase
IPR005938--AAA_ATPase_CDC48
IPR009010--Asp_de-COase-like_dom
IPR003959--ATPase_AAA_core
IPR003960--ATPase_AAA_CS
IPR004201--Cdc48_dom2
IPR029067--CDC48_domain_2-like
IPR003338--CDC4_N-term_subdom
IPR027417--P-loop_NTPase
IPR015415--Vps4_C

PROSITE

PS00674--AAA

Pfam

PF00004--AAA
PF02933--CDC48_2
PF02359--CDC48_N
PF09336--Vps4_C

SMART

SM00382--AAA
SM01072--CDC48_2
SM01073--CDC48_N

Gene Ontology

GO:0005829--C:cytosol
GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0070062--C:extracellular exosome
GO:0005811--C:lipid particle
GO:0043209--C:myelin sheath
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0000502--C:proteasome complex
GO:0035861--C:site of double-strand break
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1990730--C:VCP-NSFL1C complex
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0035800--F:deubiquitinase activator activity
GO:0003723--F:RNA binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070842--P:aggresome assembly
GO:0046034--P:ATP metabolic process
GO:0097352--P:autophagosome maturation
GO:0006302--P:double-strand break repair
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0072389--P:flavin adenine dinucleotide catabolic process
GO:0006734--P:NADH metabolic process
GO:2001171--P:positive regulation of ATP biosynthetic process
GO:1903007--P:positive regulation of Lys63-specific deubiquitinase activity
GO:0010918--P:positive regulation of mitochondrial membrane potential
GO:1903862--P:positive regulation of oxidative phosphorylation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031334--P:positive regulation of protein complex assembly
GO:0034214--P:protein hexamerization
GO:0018279--P:protein N-linked glycosylation via asparagine
GO:0016567--P:protein ubiquitination
GO:1903715--P:regulation of aerobic respiration
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0019985--P:translesion synthesis
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0019079--P:viral genome replication

KEGG

acs:100554912

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000524	Aegilops tauschii	80.31	0.00e+00	1195.00
IUUC-Aml-001849	Ailuropoda melanoleuca	97.25	0.00e+00	1477.00
IUUC-Atr-002619	Amborella trichopoda	80.00	0.00e+00	1243.00
IUUC-Apl-004070	Anas platyrhynchos	97.03	0.00e+00	1475.00
IUUC-Aly-005406	Arabidopsis lyrata	78.24	0.00e+00	1219.00
IUUC-Ath-006796	Arabidopsis thaliana	79.69	0.00e+00	1225.00
IUUC-Ago-008001	Ashbya gossypii	70.99	0.00e+00	1039.00
IUUC-Acl-008066	Aspergillus clavatus	73.14	0.00e+00	1102.00
IUUC-Afl-008505	Aspergillus flavus	70.88	0.00e+00	1125.00
IUUC-Afu-008840	Aspergillus fumigatus	73.31	0.00e+00	1123.00
IUUC-Ani-009368	Aspergillus nidulans	70.94	0.00e+00	1132.00
IUUC-Ang-009724	Aspergillus niger	71.22	0.00e+00	1129.00
IUUC-Aor-010204	Aspergillus oryzae	70.88	0.00e+00	1125.00
IUUC-Ate-010370	Aspergillus terreus	71.38	0.00e+00	1130.00
IUUC-Ame-011388	Astyanax mexicanus	95.04	0.00e+00	1433.00
IUUC-Bgr-012223	Blumeria graminis	71.68	0.00e+00	1140.00
IUUC-Bta-013188	Bos taurus	97.15	0.00e+00	1487.00
IUUC-Bci-013831	Botrytis cinerea	72.75	0.00e+00	1125.00
IUUC-Bdi-014967	Brachypodium distachyon	80.45	0.00e+00	1235.00
IUUC-Bol-016113	Brassica oleracea	79.66	0.00e+00	1224.00
IUUC-Bra-017796	Brassica rapa	79.66	0.00e+00	1227.00
IUUC-Cel-018243	Caenorhabditis elegans	76.77	0.00e+00	1207.00
IUUC-Cja-019904	Callithrix jacchus	96.53	0.00e+00	1439.00
IUUC-Cfa-020304	Canis familiaris	97.15	0.00e+00	1486.00
IUUC-Cpo-021518	Cavia porcellus	97.26	0.00e+00	1476.00
IUUC-Cre-022719	Chlamydomonas reinhardtii	79.89	0.00e+00	1222.00
IUUC-Csa-023444	Chlorocebus sabaeus	97.27	0.00e+00	1484.00
IUUC-Cho-024482	Choloepus hoffmanni	96.00	0.00e+00	1445.00
IUUC-Cin-025517	Ciona intestinalis	86.33	0.00e+00	1278.00
IUUC-Csv-026060	Ciona savignyi	86.71	0.00e+00	1329.00
IUUC-Cgl-026690	Colletotrichum gloeosporioides	72.81	0.00e+00	1152.00
IUUC-Cne-026910	Cryptococcus neoformans	72.00	0.00e+00	1169.00
IUUC-Cme-027145	Cyanidioschyzon merolae	75.00	0.00e+00	1163.00
IUUC-Dre-028487	Danio rerio	95.42	0.00e+00	1435.00
IUUC-Dno-029257	Dasypus novemcinctus	97.27	0.00e+00	1484.00
IUUC-Dor-030473	Dipodomys ordii	95.67	0.00e+00	1435.00
IUUC-Dse-031319	Dothistroma septosporum	70.90	0.00e+00	1097.00
IUUC-Dme-032203	Drosophila melanogaster	82.50	0.00e+00	1274.00
IUUC-Eca-033311	Equus caballus	96.63	0.00e+00	1463.00
IUUC-Eeu-035293	Erinaceus europaeus	98.24	0.00e+00	765.00
IUUC-Fca-036097	Felis catus	99.45	0.00e+00	1388.00
IUUC-Fal-037292	Ficedula albicollis	97.63	0.00e+00	1478.00
IUUC-Fox-037827	Fusarium oxysporum	73.20	0.00e+00	1150.00
IUUC-Fso-038226	Fusarium solani	73.07	0.00e+00	1157.00
IUUC-Gmo-039157	Gadus morhua	88.14	0.00e+00	1305.00
IUUC-Ggr-039951	Gaeumannomyces graminis	72.55	0.00e+00	1122.00
IUUC-Gga-041183	Gallus gallus	97.52	0.00e+00	1488.00
IUUC-Gac-042039	Gasterosteus aculeatus	94.18	0.00e+00	1422.00
IUUC-Gma-044090	Glycine max	77.05	0.00e+00	1256.00
IUUC-Ggo-045568	Gorilla gorilla	97.27	0.00e+00	1484.00
IUUC-Hsa-046162	Homo sapiens	97.27	0.00e+00	1484.00
IUUC-Hvu-047107	Hordeum vulgare	80.16	0.00e+00	994.00
IUUC-Itr-047885	Ictidomys tridecemlineatus	97.03	0.00e+00	1480.00
IUUC-Kpa-049220	Komagataella pastoris	68.53	0.00e+00	1102.00
IUUC-Lch-050657	Latimeria chalumnae	88.39	0.00e+00	1281.00
IUUC-Lpe-051083	Leersia perrieri	79.92	0.00e+00	1224.00
IUUC-Loc-052064	Lepisosteus oculatus	95.66	0.00e+00	1439.00
IUUC-Lma-053323	Leptosphaeria maculans	73.54	0.00e+00	1133.00
IUUC-Laf-054574	Loxodonta africana	97.38	0.00e+00	1475.00
IUUC-Mcc-055448	Macaca mulatta	97.27	0.00e+00	1484.00
IUUC-Meu-056316	Macropus eugenii	90.51	0.00e+00	1343.00
IUUC-Mor-057057	Magnaporthe oryzae	72.52	0.00e+00	1120.00
IUUC-Mpo-057406	Magnaporthe poae	72.68	0.00e+00	1116.00
IUUC-Mtr-057648	Medicago truncatula	78.95	0.00e+00	1242.00
IUUC-Mla-059156	Melampsora laricipopulina	73.85	0.00e+00	1207.00
IUUC-Mga-060004	Meleagris gallopavo	91.41	0.00e+00	1241.00
IUUC-Mvi-060488	Microbotryum violaceum	75.03	0.00e+00	1190.00
IUUC-Mmr-061027	Microcebus murinus	97.38	0.00e+00	1473.00
IUUC-Mdo-062159	Monodelphis domestica	97.27	0.00e+00	1484.00
IUUC-Mmu-063633	Mus musculus	97.27	0.00e+00	1484.00
IUUC-Mac-064919	Musa acuminata	79.19	0.00e+00	1226.00
IUUC-Mpu-066078	Mustela putorius furo	97.15	0.00e+00	1487.00
IUUC-Mlu-067757	Myotis lucifugus	97.15	0.00e+00	1484.00
IUUC-Nfi-068533	Neosartorya fischeri	73.31	0.00e+00	1115.00
IUUC-Ncr-068775	Neurospora crassa	73.23	0.00e+00	1093.00
IUUC-Nle-069424	Nomascus leucogenys	97.38	0.00e+00	1475.00
IUUC-Opr-071147	Ochotona princeps	97.92	0.00e+00	1439.00
IUUC-Ont-071351	Oreochromis niloticus	94.42	0.00e+00	1402.00
IUUC-Oan-073335	Ornithorhynchus anatinus	97.14	0.00e+00	1479.00
IUUC-Ocu-074072	Oryctolagus cuniculus	97.27	0.00e+00	1484.00
IUUC-Oba-075914	Oryza barthii	80.34	0.00e+00	1244.00
IUUC-Obr-076224	Oryza brachyantha	80.79	0.00e+00	1238.00
IUUC-Ogl-077282	Oryza glaberrima	79.87	0.00e+00	1244.00
IUUC-Ogu-078174	Oryza glumaepatula	80.34	0.00e+00	1244.00
IUUC-Oin-079103	Oryza indica	80.34	0.00e+00	1244.00
IUUC-Olo-080675	Oryza longistaminata	80.47	0.00e+00	1244.00
IUUC-Ome-081247	Oryza meridionalis	79.79	0.00e+00	1246.00
IUUC-Oni-082078	Oryza nivara	80.21	0.00e+00	1243.00
IUUC-Opu-083806	Oryza punctata	80.37	0.00e+00	1249.00
IUUC-Oru-084634	Oryza rufipogon	80.34	0.00e+00	1246.00
IUUC-Osa-085960	Oryza sativa	80.34	0.00e+00	1244.00
IUUC-Ola-086382	Oryzias latipes	94.44	0.00e+00	1397.00
IUUC-Olu-087839	Ostreococcus lucimarinus	78.37	0.00e+00	1207.00
IUUC-Oga-088037	Otolemur garnettii	97.03	0.00e+00	1476.00
IUUC-Oar-089684	Ovis aries	96.40	0.00e+00	1475.00
IUUC-Ptr-091378	Pan troglodytes	97.27	0.00e+00	1484.00
IUUC-Pan-092849	Papio anubis	97.27	0.00e+00	1484.00
IUUC-Psi-093725	Pelodiscus sinensis	96.85	0.00e+00	1394.00
IUUC-Pma-094537	Petromyzon marinus	89.43	0.00e+00	692.00
IUUC-Pno-094915	Phaeosphaeria nodorum	76.36	0.00e+00	1077.00
IUUC-Ppa-095632	Physcomitrella patens	79.45	0.00e+00	1193.00
IUUC-Pfo-097440	Poecilia formosa	94.55	0.00e+00	1400.00
IUUC-Pab-098469	Pongo abelii	97.27	0.00e+00	1484.00
IUUC-Pop-100047	Populus trichocarpa	79.66	0.00e+00	1247.00
IUUC-Pca-100399	Procavia capensis	92.81	0.00e+00	1390.00
IUUC-Ppe-101767	Prunus persica	78.62	0.00e+00	1248.00
IUUC-Pva-102426	Pteropus vampyrus	96.53	0.00e+00	1442.00
IUUC-Pgr-103599	Puccinia graminis	74.17	0.00e+00	1186.00
IUUC-Ptt-103740	Puccinia triticina	74.29	0.00e+00	1187.00
IUUC-Pte-104030	Pyrenophora teres	73.20	0.00e+00	1117.00
IUUC-Pyt-104541	Pyrenophora triticirepentis	73.10	0.00e+00	1118.00
IUUC-Rno-105144	Rattus norvegicus	97.15	0.00e+00	1481.00
IUUC-Sce-106244	Saccharomyces cerevisiae	69.85	0.00e+00	1048.00
IUUC-Sha-106589	Sarcophilus harrisii	97.38	0.00e+00	1475.00
IUUC-Sja-107673	Schizosaccharomyces japonicus	69.45	0.00e+00	1098.00
IUUC-Spo-108247	Schizosaccharomyces pombe	69.95	0.00e+00	1073.00
IUUC-Ssl-108642	Sclerotinia sclerotiorum	72.49	0.00e+00	1116.00
IUUC-Smo-108877	Selaginella moellendorffii	79.48	0.00e+00	1230.00
IUUC-Sit-110623	Setaria italica	79.87	0.00e+00	1245.00
IUUC-Sly-111151	Solanum lycopersicum	76.79	0.00e+00	1221.00
IUUC-Stu-111959	Solanum tuberosum	77.26	0.00e+00	1249.00
IUUC-Sar-113021	Sorex araneus	97.38	0.00e+00	1474.00
IUUC-Sbi-114457	Sorghum bicolor	80.36	0.00e+00	1246.00
IUUC-Sre-115052	Sporisorium reilianum	76.87	0.00e+00	1215.00
IUUC-Ssc-116293	Sus scrofa	96.91	0.00e+00	1482.00
IUUC-Tgu-116544	Taeniopygia guttata	94.39	0.00e+00	1394.00
IUUC-Tru-117991	Takifugu rubripes	93.88	0.00e+00	996.00
IUUC-Tsy-119131	Tarsius syrichta	98.69	0.00e+00	740.00
IUUC-Tni-120192	Tetraodon nigroviridis	93.68	0.00e+00	1387.00
IUUC-Tca-121502	Theobroma cacao	79.35	0.00e+00	1220.00
IUUC-Tre-122189	Trichoderma reesei	72.68	0.00e+00	1132.00
IUUC-Tvi-122310	Trichoderma virens	72.16	0.00e+00	1117.00
IUUC-Tae-124332	Triticum aestivum	80.31	0.00e+00	1213.00
IUUC-Tur-126733	Triticum urartu	80.05	0.00e+00	1199.00
IUUC-Tme-127147	Tuber melanosporum	73.11	0.00e+00	1109.00
IUUC-Tbe-127255	Tupaia belangeri	90.22	0.00e+00	1377.00
IUUC-Ttr-128876	Tursiops truncatus	96.62	0.00e+00	1457.00
IUUC-Uma-129448	Ustilago maydis	77.10	0.00e+00	1208.00
IUUC-Vda-129800	Verticillium dahliae	70.30	0.00e+00	1117.00
IUUC-Vpa-130573	Vicugna pacos	99.06	0.00e+00	831.00
IUUC-Vvi-131622	Vitis vinifera	80.78	0.00e+00	1251.00
IUUC-Xtr-132458	Xenopus tropicalis	99.32	0.00e+00	1395.00
IUUC-Xma-134045	Xiphophorus maculatus	94.55	0.00e+00	1400.00
IUUC-Yli-134382	Yarrowia lipolytica	71.89	0.00e+00	1128.00
IUUC-Zma-134817	Zea mays	80.10	0.00e+00	1250.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence