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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-105047
Ensembl Protein ID ENSRNOP00000012551.2
UniProt Accession P0C627; UBX2B_RAT
Genbank Protein ID ENSRNOP00000012551
Protein Name UBX domain-containing protein 2B; NSFL1 cofactor p37; p97 cofactor p37
Genbank Nucleotide ID AABR03041043
Gene Name Ubxn2b
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000009137.4 ENSRNOT00000012551.4 ENSRNOP00000012551.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFACRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusUniProt
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
ULD/UDP/UFD/UBX 1.50e-15 57.8 255 328
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   ULD/UDP/UFD/UBX
   S: 4    eqatlqiRlpdGkrlvrkFpssttleqiyqfve.yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsll 78
           +++++qiRl+dG+rl ++F+s++++ ++++f+   +  +  + F Lv++fP ++l++e+   tlq+a+++++ +l+
   Q: 255  PTTKIQIRLADGSRLIQRFNSTHRILDVRDFIVqSRPEFATTDFILVTSFPSKELTDESV--TLQDADILNTVILQ 328
           589******************************7788889999*****************..*********99985 PP
   
Organism Rattus norvegicus
Functional Description
(View)

Functional Description


     Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity (By similarity).
 Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity (By similarity).
Protein Sequence
(Fasta)
MAEGGGAEPE EQERRSSRPR PPSARDLQLA LAELYEDEMK CKSSKPDRST ATAFKSPRTP 60
PLRLYSGDQE YGGLHIAQPP TGKIVNELFK EAREHGAVPL NEATRSSSDD KAKSFTGGGY 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105047|ULD,UBX|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTAGTGTCTT CATAGGAACG TGAAAGCCTA TGTGGGTGTA TCATACTGTT GGCAATCAAG 60
AAAAGTAGCT AAGATGTGGT AAACAGACCT CTCAGATTCA TCTTCTCTAG CTTGTAAAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105047|ULD,UBX|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR012989--SEP_domain
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom
PROSITE

PS51399--SEP
PS50033--UBX
Pfam

PF08059--SEP
PF00789--UBX
SMART

SM00553--SEP
SM00166--UBX
Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005794--C:Golgi apparatus
GO:0005634--C:nucleus
GO:0043130--F:ubiquitin binding
GO:0007030--P:Golgi organization
GO:0061025--P:membrane fusion
GO:0031468--P:nuclear envelope reassembly
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
KEGG rno:312965
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001637 Ailuropoda melanoleuca 87.61 3.00e-167 580.00
IUUC-Apl-003738 Anas platyrhynchos 72.75 5.00e-124 437.00
IUUC-Aca-005097 Anolis carolinensis 73.70 2.00e-121 428.00
IUUC-Acl-008176 Aspergillus clavatus 39.23 6.00e-30 124.00
IUUC-Afl-008553 Aspergillus flavus 36.46 2.00e-26 112.00
IUUC-Afu-008919 Aspergillus fumigatus 37.57 2.00e-29 123.00
IUUC-Aor-010016 Aspergillus oryzae 36.46 3.00e-26 112.00
IUUC-Bgr-012256 Blumeria graminis 34.47 4.00e-27 115.00
IUUC-Bta-012629 Bos taurus 87.01 6.00e-151 526.00
IUUC-Bci-013750 Botrytis cinerea 32.10 1.00e-28 120.00
IUUC-Bdi-014204 Brachypodium distachyon 32.04 2.00e-33 137.00
IUUC-Cja-019732 Callithrix jacchus 78.85 1.00e-136 479.00
IUUC-Cfa-021132 Canis familiaris 87.01 1.00e-166 578.00
IUUC-Cpo-021389 Cavia porcellus 86.36 6.00e-158 549.00
IUUC-Csa-023362 Chlorocebus sabaeus 87.61 4.00e-166 577.00
IUUC-Cgl-026628 Colletotrichum gloeosporioides 32.58 4.00e-23 102.00
IUUC-Dno-029956 Dasypus novemcinctus 86.79 1.00e-151 528.00
IUUC-Dor-031124 Dipodomys ordii 80.84 8.00e-136 476.00
IUUC-Eca-034063 Equus caballus 87.61 3.00e-166 577.00
IUUC-Fca-035606 Felis catus 86.40 1.00e-164 572.00
IUUC-Fal-036923 Ficedula albicollis 72.29 2.00e-122 432.00
IUUC-Ggr-039971 Gaeumannomyces graminis 29.38 8.00e-15 75.10
IUUC-Gga-040906 Gallus gallus 74.92 1.00e-135 476.00
IUUC-Gma-044296 Glycine max 34.43 6.00e-36 144.00
IUUC-Ggo-044801 Gorilla gorilla 88.96 1.00e-162 565.00
IUUC-Hsa-046853 Homo sapiens 88.96 1.00e-162 565.00
IUUC-Hvu-047203 Hordeum vulgare 33.46 7.00e-31 127.00
IUUC-Itr-047910 Ictidomys tridecemlineatus 91.22 1.00e-141 495.00
IUUC-Lpe-051122 Leersia perrieri 34.17 1.00e-34 140.00
IUUC-Lma-053319 Leptosphaeria maculans 34.34 5.00e-34 138.00
IUUC-Laf-053854 Loxodonta africana 85.44 9.00e-145 506.00
IUUC-Mcc-055607 Macaca mulatta 87.31 1.00e-161 561.00
IUUC-Mpo-057595 Magnaporthe poae 28.09 1.00e-18 87.40
IUUC-Mga-059714 Meleagris gallopavo 74.92 5.00e-135 473.00
IUUC-Mmr-061091 Microcebus murinus 90.58 6.00e-165 573.00
IUUC-Mdo-062985 Monodelphis domestica 83.01 2.00e-139 488.00
IUUC-Mmu-064382 Mus musculus 91.84 2.00e-169 587.00
IUUC-Mpu-066168 Mustela putorius furo 89.61 1.00e-163 568.00
IUUC-Mlu-067562 Myotis lucifugus 83.69 5.00e-150 523.00
IUUC-Nfi-068609 Neosartorya fischeri 38.12 1.00e-29 123.00
IUUC-Ncr-068786 Neurospora crassa 33.87 3.00e-24 106.00
IUUC-Nle-069639 Nomascus leucogenys 89.29 4.00e-163 566.00
IUUC-Oan-073007 Ornithorhynchus anatinus 82.57 4.00e-147 513.00
IUUC-Ocu-074507 Oryctolagus cuniculus 88.52 2.00e-166 577.00
IUUC-Oba-075011 Oryza barthii 33.70 2.00e-33 135.00
IUUC-Obr-076164 Oryza brachyantha 35.68 6.00e-28 117.00
IUUC-Ogl-077805 Oryza glaberrima 33.70 2.00e-33 135.00
IUUC-Ogu-078942 Oryza glumaepatula 33.70 1.00e-33 137.00
IUUC-Oin-079497 Oryza indica 34.07 1.00e-32 134.00
IUUC-Olo-080254 Oryza longistaminata 35.94 8.00e-30 124.00
IUUC-Ome-081766 Oryza meridionalis 34.43 6.00e-32 132.00
IUUC-Oni-082258 Oryza nivara 33.70 2.00e-33 135.00
IUUC-Opu-083365 Oryza punctata 34.06 1.00e-35 143.00
IUUC-Oru-084748 Oryza rufipogon 33.70 1.00e-33 137.00
IUUC-Osa-085359 Oryza sativa 33.70 2.00e-33 135.00
IUUC-Oga-088292 Otolemur garnettii 77.52 5.00e-138 483.00
IUUC-Oar-090236 Ovis aries 85.71 2.00e-146 511.00
IUUC-Ptr-090664 Pan troglodytes 88.96 1.00e-162 565.00
IUUC-Pan-092072 Papio anubis 87.83 3.00e-159 553.00
IUUC-Psi-093486 Pelodiscus sinensis 77.99 2.00e-129 455.00
IUUC-Pno-094769 Phaeosphaeria nodorum 32.16 7.00e-34 138.00
IUUC-Pab-097813 Pongo abelii 88.96 1.00e-162 565.00
IUUC-Pca-100985 Procavia capensis 73.13 3.00e-102 364.00
IUUC-Ppe-101417 Prunus persica 34.30 1.00e-34 140.00
IUUC-Pva-102600 Pteropus vampyrus 88.58 3.00e-162 564.00
IUUC-Pte-104083 Pyrenophora teres 40.61 2.00e-39 156.00
IUUC-Sha-106777 Sarcophilus harrisii 77.99 3.00e-67 248.00
IUUC-Sja-107717 Schizosaccharomyces japonicus 31.70 4.00e-30 125.00
IUUC-Sbi-114513 Sorghum bicolor 33.33 8.00e-35 141.00
IUUC-Sre-115176 Sporisorium reilianum 38.66 3.00e-32 133.00
IUUC-Ssc-115936 Sus scrofa 88.64 3.00e-150 524.00
IUUC-Tgu-116752 Taeniopygia guttata 73.65 1.00e-125 442.00
IUUC-Tsy-119015 Tarsius syrichta 76.95 1.00e-133 469.00
IUUC-Tca-121311 Theobroma cacao 35.51 6.00e-32 130.00
IUUC-Ttr-128760 Tursiops truncatus 88.64 1.00e-151 528.00
IUUC-Vpa-130155 Vicugna pacos 86.47 9.00e-149 519.00
IUUC-Vvi-131338 Vitis vinifera 32.88 1.00e-32 133.00
Created Date 25-Jun-2017

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