iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt	PHOSIDA
BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	28.57	4.30e-02	37.00	IUUC-Mmu-063613

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Saccharomyces cerevisiae

Functional Description
(View)

TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauA domain of TFIIIC that binds boxA DNA promoter sites of tRNA and similar genes.

Protein Sequence
(Fasta)

MVVNTIYIAR HGYRSNWLPE GPYPDPLTGI DSDVPLAEHG VQQAKELAHY LLSLDNQPEA 60
AFASPFYRCL ETVQPIAKLL EIPVYLERGI GEWYRPDRKP VIPVPAGYEI LSKFFPGVIS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGGTGA ACACGATATA TATCGCAAGG CATGGATACA GATCCAACTG GCTTCCGGAG 60
GGTCCATATC CTGACCCACT TACAGGAATT GATAGCGATG TTCCTTTAGC AGAACACGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR013078--His_Pase_superF_clade-1
IPR029033--His_PPase_superfam
IPR014623--Tfc7/tau55
IPR019481--TFIIIC_tau55-rel

Pfam

PF00300--His_Phos_1
PF10419--TFIIIC_sub6

SMART

SM00855--PGAM

Gene Ontology

GO:0000127--C:transcription factor TFIIIC complex
GO:0003677--F:DNA binding
GO:0016791--F:phosphatase activity
GO:0042791--P:5S class rRNA transcription from RNA polymerase III type 1 promoter
GO:0016311--P:dephosphorylation
GO:0006359--P:regulation of transcription from RNA polymerase III promoter
GO:0000999--P:RNA polymerase III type 1 promoter transcriptional preinitiation complex assembly
GO:0001021--P:RNA polymerase III type 2 promoter transcriptional preinitiation complex assembly
GO:0001041--P:transcription from a RNA polymerase III hybrid type promoter
GO:0001009--P:transcription from RNA polymerase III type 2 promoter

KEGG

sce:YOR110W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004356	Anolis carolinensis	26.51	1.00e-05	42.40
IUUC-Aly-006369	Arabidopsis lyrata	29.27	4.00e-03	33.10
IUUC-Ath-006661	Arabidopsis thaliana	25.88	2.10e-02	30.80
IUUC-Bgr-012101	Blumeria graminis	29.59	6.00e-27	112.00
IUUC-Bci-013728	Botrytis cinerea	32.86	2.00e-28	117.00
IUUC-Bol-015778	Brassica oleracea	25.85	6.00e-03	32.70
IUUC-Bra-017339	Brassica rapa	28.05	6.30e-02	29.30
IUUC-Cel-018530	Caenorhabditis elegans	26.74	4.00e-04	36.60
IUUC-Cin-025372	Ciona intestinalis	25.15	1.60e-02	32.30
IUUC-Cgl-026592	Colletotrichum gloeosporioides	31.10	1.00e-23	101.00
IUUC-Cme-027186	Cyanidioschyzon merolae	38.14	1.00e-11	61.60
IUUC-Dno-028890	Dasypus novemcinctus	26.82	4.00e-06	44.30
IUUC-Dse-031474	Dothistroma septosporum	32.53	9.00e-31	124.00
IUUC-Eca-033634	Equus caballus	24.07	6.00e-06	43.90
IUUC-Gma-044050	Glycine max	33.78	2.00e-03	34.30
IUUC-Itr-048502	Ictidomys tridecemlineatus	23.86	4.00e-04	36.60
IUUC-Lch-049841	Latimeria chalumnae	28.21	3.00e-05	41.60
IUUC-Lma-053306	Leptosphaeria maculans	31.00	2.00e-27	114.00
IUUC-Mmu-063613	Mus musculus	28.57	1.00e-03	36.60
IUUC-Mac-064775	Musa acuminata	24.35	4.00e-03	33.10
IUUC-Mlu-068057	Myotis lucifugus	27.42	3.00e-06	45.10
IUUC-Oba-075491	Oryza barthii	24.32	2.00e-05	40.80
IUUC-Obr-076070	Oryza brachyantha	28.74	2.90e-02	30.40
IUUC-Ogl-077162	Oryza glaberrima	24.32	2.00e-05	40.80
IUUC-Oin-080005	Oryza indica	24.46	2.00e-05	40.40
IUUC-Oni-082745	Oryza nivara	24.46	1.00e-05	41.20
IUUC-Opu-084066	Oryza punctata	24.06	6.00e-06	42.40
IUUC-Oru-084674	Oryza rufipogon	24.32	2.00e-05	40.40
IUUC-Osa-085577	Oryza sativa	24.46	2.00e-05	40.40
IUUC-Pop-099403	Populus trichocarpa	27.06	2.40e-01	27.30
IUUC-Pca-100920	Procavia capensis	29.49	2.60e-01	28.50
IUUC-Ppe-101806	Prunus persica	32.93	3.30e-02	30.00
IUUC-Pyt-104727	Pyrenophora triticirepentis	29.00	9.00e-26	108.00
IUUC-Ssl-108385	Sclerotinia sclerotiorum	30.77	5.00e-23	99.40
IUUC-Smo-109333	Selaginella moellendorffii	27.78	6.20e-02	29.30
IUUC-Sly-111172	Solanum lycopersicum	26.83	1.40e-01	27.70
IUUC-Stu-112768	Solanum tuberosum	26.83	1.40e-01	27.70
IUUC-Tgu-117193	Taeniopygia guttata	25.86	8.00e-06	42.70
IUUC-Uma-129616	Ustilago maydis	30.80	2.00e-28	117.00
IUUC-Vda-129751	Verticillium dahliae	31.23	1.00e-33	135.00
IUUC-Yli-134663	Yarrowia lipolytica	38.42	3.00e-63	233.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence