iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067899

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02012652

Gene Name

RNF139

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000026526.1	ENSMLUT00000029857.1	ENSMLUP00000020635.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.90e-08	34.2	547	585

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC+ +f +  + +pC+H fha Cl kw       + +++CP C
   Q: 547  CAICYHEFTTSARMTPCNHYFHALCLRKW------LYIQDTCPMC 585
           ********999******************......********** PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MAAVGPPQQQ VRMAHQQAWA ALEVALRVPC LYIIDAIFNS YYDSSQSRFC IGLQIFLRLL 60
GIFVSSIVLI LSQRSLFKFY MYSAAFLLAA TSVLVNYYAV LHIDFYGAYN TSAFGIELLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG TGGGGCCCCC GCAGCAGCAG GTGCGGATGG CCCATCAGCA GGCCTGGGCG 60
GCGCTCGAAG TGGCGCTCCG GGTGCCCTGC CTCTACATCA TCGACGCCAT CTTCAACTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0036503--P:ERAD pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0017148--P:negative regulation of translation
GO:2000060--P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031648--P:protein destabilization
GO:0060628--P:regulation of ER to Golgi vesicle-mediated transport
GO:0070613--P:regulation of protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002401	Ailuropoda melanoleuca	94.86	0.00e+00	1211.00
IUUC-Apl-004214	Anas platyrhynchos	85.06	0.00e+00	950.00
IUUC-Aca-005326	Anolis carolinensis	77.36	0.00e+00	967.00
IUUC-Ame-011687	Astyanax mexicanus	74.08	0.00e+00	865.00
IUUC-Bta-013394	Bos taurus	94.14	0.00e+00	1240.00
IUUC-Bci-013813	Botrytis cinerea	41.38	1.00e-07	50.80
IUUC-Cja-019499	Callithrix jacchus	93.08	0.00e+00	1253.00
IUUC-Cfa-020357	Canis familiaris	94.74	0.00e+00	1219.00
IUUC-Cpo-021924	Cavia porcellus	93.62	0.00e+00	1163.00
IUUC-Csa-023513	Chlorocebus sabaeus	94.14	0.00e+00	1236.00
IUUC-Cho-024285	Choloepus hoffmanni	87.84	0.00e+00	1080.00
IUUC-Cin-025223	Ciona intestinalis	53.56	4.00e-74	271.00
IUUC-Csv-026018	Ciona savignyi	47.00	6.00e-64	237.00
IUUC-Dre-028660	Danio rerio	71.98	0.00e+00	782.00
IUUC-Dno-029463	Dasypus novemcinctus	94.93	2.00e-165	575.00
IUUC-Dor-030728	Dipodomys ordii	92.14	0.00e+00	1077.00
IUUC-Dse-031284	Dothistroma septosporum	46.55	7.00e-09	54.30
IUUC-Dme-032186	Drosophila melanogaster	45.08	2.00e-98	353.00
IUUC-Ete-032368	Echinops telfairi	88.01	0.00e+00	1161.00
IUUC-Eca-034325	Equus caballus	94.59	0.00e+00	1186.00
IUUC-Fca-035537	Felis catus	93.27	0.00e+00	1169.00
IUUC-Fal-037459	Ficedula albicollis	84.83	0.00e+00	928.00
IUUC-Gmo-039442	Gadus morhua	78.65	2.00e-98	353.00
IUUC-Gga-041071	Gallus gallus	81.60	0.00e+00	979.00
IUUC-Gac-042483	Gasterosteus aculeatus	66.41	0.00e+00	893.00
IUUC-Ggo-044672	Gorilla gorilla	93.98	0.00e+00	1236.00
IUUC-Hsa-045836	Homo sapiens	93.53	0.00e+00	1206.00
IUUC-Itr-048588	Ictidomys tridecemlineatus	94.52	0.00e+00	1246.00
IUUC-Lch-050073	Latimeria chalumnae	72.05	0.00e+00	962.00
IUUC-Loc-052908	Lepisosteus oculatus	69.66	0.00e+00	937.00
IUUC-Lma-053202	Leptosphaeria maculans	42.59	3.00e-08	52.00
IUUC-Laf-053519	Loxodonta africana	91.14	0.00e+00	1234.00
IUUC-Mcc-054674	Macaca mulatta	93.43	3.00e-103	367.00
IUUC-Mor-057262	Magnaporthe oryzae	31.31	1.00e-08	55.50
IUUC-Mga-059922	Meleagris gallopavo	84.66	0.00e+00	949.00
IUUC-Mmr-061452	Microcebus murinus	93.39	0.00e+00	1168.00
IUUC-Mdo-062412	Monodelphis domestica	89.14	0.00e+00	1170.00
IUUC-Mmu-063147	Mus musculus	91.92	0.00e+00	1208.00
IUUC-Mpu-065929	Mustela putorius furo	94.89	0.00e+00	1219.00
IUUC-Nle-070083	Nomascus leucogenys	93.98	0.00e+00	1234.00
IUUC-Opr-070461	Ochotona princeps	89.66	0.00e+00	1211.00
IUUC-Ont-072256	Oreochromis niloticus	69.67	0.00e+00	905.00
IUUC-Oan-073150	Ornithorhynchus anatinus	82.62	0.00e+00	918.00
IUUC-Ocu-073748	Oryctolagus cuniculus	91.45	0.00e+00	1197.00
IUUC-Oga-088565	Otolemur garnettii	94.07	0.00e+00	1216.00
IUUC-Oar-089432	Ovis aries	93.72	0.00e+00	1149.00
IUUC-Ptr-091422	Pan troglodytes	93.83	0.00e+00	1235.00
IUUC-Pan-092331	Papio anubis	93.98	0.00e+00	1235.00
IUUC-Psi-092933	Pelodiscus sinensis	83.39	0.00e+00	933.00
IUUC-Pfo-097466	Poecilia formosa	63.89	0.00e+00	906.00
IUUC-Pab-098702	Pongo abelii	93.83	0.00e+00	1234.00
IUUC-Pca-100125	Procavia capensis	90.64	0.00e+00	1191.00
IUUC-Ppe-101613	Prunus persica	32.69	4.00e-11	60.80
IUUC-Pva-102628	Pteropus vampyrus	94.42	0.00e+00	1211.00
IUUC-Rno-104886	Rattus norvegicus	92.07	0.00e+00	1217.00
IUUC-Sha-106702	Sarcophilus harrisii	86.27	0.00e+00	1144.00
IUUC-Ssc-116164	Sus scrofa	93.24	0.00e+00	1258.00
IUUC-Tgu-116829	Taeniopygia guttata	82.94	0.00e+00	962.00
IUUC-Tru-118557	Takifugu rubripes	65.77	0.00e+00	870.00
IUUC-Tsy-119399	Tarsius syrichta	90.51	0.00e+00	667.00
IUUC-Tni-120006	Tetraodon nigroviridis	60.03	0.00e+00	760.00
IUUC-Tca-121057	Theobroma cacao	38.67	5.00e-10	57.80
IUUC-Tbe-127664	Tupaia belangeri	92.76	0.00e+00	1189.00
IUUC-Ttr-129144	Tursiops truncatus	92.94	0.00e+00	1236.00
IUUC-Vpa-130226	Vicugna pacos	94.14	0.00e+00	1236.00
IUUC-Vvi-131278	Vitis vinifera	39.29	4.00e-10	57.80
IUUC-Xtr-132461	Xenopus tropicalis	75.94	0.00e+00	899.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence