iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022445

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02033409

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000001491.3	ENSCPOT00000001511.2	ENSCPOP00000001347.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.70e-16	59.6	66	131
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.70e-08	32.3	165	196

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+ La   ++F+a+fl+e+ e k +  +ei+d + ++ ++l++F+Y+++l++
   Q: 66   CDVTLKVGSKLISCHKLALACVIPYFRAMFLSEMAEAK-QTLIEIRDFDGDAIEDLVRFVYSSRLTL 131
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+ +++ hF+
   Q: 165  PSNCLAVRAFAESHNRMDLMDMADQYACEHFT 196
           89*****************************7 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MASEPVTGKP ARNHFPKGKR QQLQPTKTRS AASDCDREDS FVFEANEAWK DFHSSLLRFY 60
ENGELCDVTL KVGSKLISCH KLALACVIPY FRAMFLSEMA EAKQTLIEIR DFDGDAIEDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCAG AACCAGTGAC TGGGAAGCCA GCTCGGAACC ACTTCCCGAA GGGGAAGCGG 60
CAGCAGCTGC AGCCCACGAA GACCAGGTCT GCAGCAAGCG ACTGTGACAG AGAAGACTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	94.18	0.00e+00	1198.00
IUUC-Atr-002726	Amborella trichopoda	36.29	1.00e-43	171.00
IUUC-Apl-003978	Anas platyrhynchos	88.37	0.00e+00	1145.00
IUUC-Aca-004958	Anolis carolinensis	85.16	0.00e+00	1072.00
IUUC-Ame-011139	Astyanax mexicanus	82.39	0.00e+00	1072.00
IUUC-Bta-013142	Bos taurus	94.51	0.00e+00	1194.00
IUUC-Bdi-014143	Brachypodium distachyon	40.00	2.00e-43	170.00
IUUC-Cel-018551	Caenorhabditis elegans	40.73	2.00e-128	452.00
IUUC-Cja-019650	Callithrix jacchus	93.39	0.00e+00	1214.00
IUUC-Cfa-021046	Canis familiaris	94.51	0.00e+00	1196.00
IUUC-Csa-023642	Chlorocebus sabaeus	93.87	0.00e+00	1217.00
IUUC-Cho-025012	Choloepus hoffmanni	78.51	0.00e+00	880.00
IUUC-Dre-027723	Danio rerio	82.06	0.00e+00	1056.00
IUUC-Dno-028964	Dasypus novemcinctus	92.38	0.00e+00	988.00
IUUC-Dor-030899	Dipodomys ordii	81.79	1.00e-133	470.00
IUUC-Ete-032815	Echinops telfairi	91.76	0.00e+00	1194.00
IUUC-Eca-034162	Equus caballus	94.67	0.00e+00	1184.00
IUUC-Eeu-034660	Erinaceus europaeus	92.41	0.00e+00	1169.00
IUUC-Fca-035659	Felis catus	94.51	0.00e+00	1201.00
IUUC-Fal-037619	Ficedula albicollis	89.18	0.00e+00	1155.00
IUUC-Gmo-038546	Gadus morhua	83.95	0.00e+00	1054.00
IUUC-Gga-040770	Gallus gallus	88.69	0.00e+00	1120.00
IUUC-Gac-042557	Gasterosteus aculeatus	79.58	0.00e+00	1041.00
IUUC-Ggo-044741	Gorilla gorilla	93.55	0.00e+00	1215.00
IUUC-Hsa-046025	Homo sapiens	93.55	0.00e+00	1216.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	95.99	0.00e+00	1086.00
IUUC-Loc-052834	Lepisosteus oculatus	87.04	0.00e+00	1008.00
IUUC-Laf-054513	Loxodonta africana	93.70	0.00e+00	1203.00
IUUC-Mcc-054707	Macaca mulatta	93.71	0.00e+00	1213.00
IUUC-Meu-056779	Macropus eugenii	88.42	0.00e+00	1145.00
IUUC-Mtr-058180	Medicago truncatula	31.92	4.00e-36	146.00
IUUC-Mga-059676	Meleagris gallopavo	88.53	0.00e+00	1118.00
IUUC-Mmr-061359	Microcebus murinus	93.55	0.00e+00	1181.00
IUUC-Mdo-062527	Monodelphis domestica	87.80	0.00e+00	1144.00
IUUC-Mmu-063112	Mus musculus	90.14	0.00e+00	1189.00
IUUC-Mac-064682	Musa acuminata	37.23	6.00e-43	169.00
IUUC-Mpu-065800	Mustela putorius furo	93.70	0.00e+00	1192.00
IUUC-Mlu-067536	Myotis lucifugus	93.00	0.00e+00	1151.00
IUUC-Nle-069397	Nomascus leucogenys	93.71	0.00e+00	1217.00
IUUC-Opr-070599	Ochotona princeps	93.54	0.00e+00	998.00
IUUC-Ont-072580	Oreochromis niloticus	80.56	0.00e+00	1048.00
IUUC-Oan-073180	Ornithorhynchus anatinus	88.69	0.00e+00	1148.00
IUUC-Ocu-074026	Oryctolagus cuniculus	94.18	0.00e+00	1180.00
IUUC-Obr-076181	Oryza brachyantha	32.03	6.00e-36	146.00
IUUC-Ola-086776	Oryzias latipes	80.07	0.00e+00	1004.00
IUUC-Oga-088651	Otolemur garnettii	94.20	0.00e+00	1190.00
IUUC-Oar-089567	Ovis aries	93.21	0.00e+00	1169.00
IUUC-Ptr-091564	Pan troglodytes	93.55	0.00e+00	1215.00
IUUC-Pan-092578	Papio anubis	93.87	0.00e+00	1217.00
IUUC-Psi-093635	Pelodiscus sinensis	87.75	0.00e+00	1088.00
IUUC-Pma-094660	Petromyzon marinus	61.82	0.00e+00	759.00
IUUC-Pfo-097507	Poecilia formosa	80.81	0.00e+00	977.00
IUUC-Pab-098025	Pongo abelii	93.55	0.00e+00	1215.00
IUUC-Pca-101046	Procavia capensis	86.03	3.00e-180	624.00
IUUC-Ppe-101154	Prunus persica	32.28	1.00e-37	151.00
IUUC-Pva-102359	Pteropus vampyrus	95.68	0.00e+00	890.00
IUUC-Rno-105750	Rattus norvegicus	91.63	0.00e+00	1177.00
IUUC-Sha-107513	Sarcophilus harrisii	89.68	0.00e+00	1165.00
IUUC-Sly-111482	Solanum lycopersicum	32.68	1.00e-41	164.00
IUUC-Stu-112032	Solanum tuberosum	33.85	2.00e-43	170.00
IUUC-Sar-113616	Sorex araneus	69.97	2.00e-116	412.00
IUUC-Ssc-116205	Sus scrofa	93.36	0.00e+00	999.00
IUUC-Tgu-117435	Taeniopygia guttata	89.50	0.00e+00	1151.00
IUUC-Tru-118709	Takifugu rubripes	79.97	0.00e+00	1037.00
IUUC-Tsy-119466	Tarsius syrichta	96.72	0.00e+00	1088.00
IUUC-Tni-119988	Tetraodon nigroviridis	80.17	0.00e+00	1033.00
IUUC-Tbe-127704	Tupaia belangeri	94.53	0.00e+00	1044.00
IUUC-Ttr-128892	Tursiops truncatus	96.11	0.00e+00	909.00
IUUC-Vpa-130545	Vicugna pacos	93.74	0.00e+00	1005.00
IUUC-Xtr-132289	Xenopus tropicalis	82.96	0.00e+00	1016.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence