iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089441

Ensembl Protein ID

ENSOARP00000007913.1

UniProt Accession

W5PBV2; W5PBV2_SHEEP

Genbank Protein ID

ENSOARP00000007913

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01090266

Gene Name

UBE3C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000007377.1	ENSOART00000008030.1	ENSOARP00000007913.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.50e-104	350.2	749	1086

Active Site

Position(s)	Description	Evidence
1054	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ + +    ++++flGr+lgkal++
   Q: 749  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGD-AFARHYYFLGRMLGKALYE 834
           689**********99**9************************************9999999999965.99***************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++ +f+++llg+  ++++++l+++dpe+y++l ++k++ e d+eelgl++t+   ++ lge++++eLk+gG++ipVt +N
   Q: 835  NMLVELPFAGFFLSKLLGTsaDVDIHHLASLDPEVYRNLLFLKSY-EGDVEELGLNFTVV--NNDLGEAQVVELKSGGKDIPVTSAN 918
           ******************9666889******************99.78999987777765..888********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl+++i+ ++ afr+G+ +v++le+l++F+++e+++li+G    i++edlk++t+y ggy++++p+i+ Fw+v+e+
   Q: 919  RIAYIHLVADYRLNRQIRPHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAqVPISLEDLKSFTNYSGGYSAEHPVIKVFWRVVEG 1005
           ****************************************************899******************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el p  f+i++ +sd +rlP+++TC+n+LkLPe++ +  l++kLlyAie ++gFels
   Q: 1006 FTDEEKRKLLKFVTSCSRPPLLGFKELYPA-FCIHNGGSDlERLPTASTCMNLLKLPEFQDEALLRSKLLYAIECAAGFELS 1086
           ****************************88.*****99999**************************************985 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MFSFEGDFKT RPKVSLGGAS RKEEKASLLH RTQEERRKRE EERRRLKNAI IIQSFIRGYR 60
DRKQQCSIQR SAFDRCASLS QSGGAFPLAS GPNLALLVRQ LLFFYRQSED SKRLIWMYQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCCCGCG CTCTCTGGGT CGGGCCCCCA GATGGGATAG GCTTTAAAGA TGTTTAGTTT 60
TGAGGGGGAC TTCAAAACCA GGCCCAAGGT GTCCCTGGGA GGCGCGAGCC GGAAGGTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	90.23	0.00e+00	1885.00
IUUC-Atr-002669	Amborella trichopoda	30.65	3.00e-101	363.00
IUUC-Apl-003731	Anas platyrhynchos	86.57	0.00e+00	1856.00
IUUC-Aca-005248	Anolis carolinensis	85.45	0.00e+00	1857.00
IUUC-Aly-005768	Arabidopsis lyrata	35.49	4.00e-109	389.00
IUUC-Ath-006576	Arabidopsis thaliana	29.35	5.00e-113	402.00
IUUC-Ago-007748	Ashbya gossypii	42.08	4.00e-78	286.00
IUUC-Acl-008158	Aspergillus clavatus	38.59	2.00e-78	287.00
IUUC-Afl-008398	Aspergillus flavus	35.07	9.00e-80	292.00
IUUC-Afu-008937	Aspergillus fumigatus	39.28	9.00e-81	295.00
IUUC-Ani-009252	Aspergillus nidulans	38.59	4.00e-82	300.00
IUUC-Ang-009773	Aspergillus niger	34.60	7.00e-80	292.00
IUUC-Aor-009940	Aspergillus oryzae	35.07	9.00e-80	292.00
IUUC-Ate-010395	Aspergillus terreus	35.65	2.00e-80	294.00
IUUC-Ame-010769	Astyanax mexicanus	62.88	0.00e+00	1036.00
IUUC-Bgr-012269	Blumeria graminis	38.04	2.00e-75	276.00
IUUC-Bta-012841	Bos taurus	98.34	0.00e+00	2039.00
IUUC-Bci-013743	Botrytis cinerea	38.76	3.00e-84	307.00
IUUC-Bdi-014123	Brachypodium distachyon	46.57	8.00e-103	368.00
IUUC-Bol-015390	Brassica oleracea	46.60	2.00e-102	367.00
IUUC-Bra-016853	Brassica rapa	35.54	5.00e-108	385.00
IUUC-Cel-018638	Caenorhabditis elegans	39.37	6.00e-90	325.00
IUUC-Cja-019743	Callithrix jacchus	90.08	0.00e+00	1896.00
IUUC-Cfa-021031	Canis familiaris	91.65	0.00e+00	1937.00
IUUC-Cpo-022401	Cavia porcellus	89.32	0.00e+00	1897.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	44.76	3.00e-86	311.00
IUUC-Csa-024107	Chlorocebus sabaeus	92.08	0.00e+00	1955.00
IUUC-Cho-024750	Choloepus hoffmanni	81.46	0.00e+00	791.00
IUUC-Cin-025432	Ciona intestinalis	45.37	3.00e-99	355.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	34.67	2.00e-89	324.00
IUUC-Cne-026841	Cryptococcus neoformans	36.26	1.00e-93	338.00
IUUC-Cme-027265	Cyanidioschyzon merolae	47.10	2.00e-103	370.00
IUUC-Dre-028196	Danio rerio	76.98	0.00e+00	1590.00
IUUC-Dno-029024	Dasypus novemcinctus	90.15	0.00e+00	1940.00
IUUC-Dor-030483	Dipodomys ordii	91.12	0.00e+00	684.00
IUUC-Dse-031416	Dothistroma septosporum	34.42	5.00e-79	289.00
IUUC-Dme-031946	Drosophila melanogaster	37.83	0.00e+00	676.00
IUUC-Ete-032240	Echinops telfairi	78.90	3.00e-168	585.00
IUUC-Eca-033828	Equus caballus	90.79	0.00e+00	1900.00
IUUC-Eeu-034604	Erinaceus europaeus	85.00	2.00e-126	447.00
IUUC-Fca-035907	Felis catus	90.98	0.00e+00	1949.00
IUUC-Fal-037389	Ficedula albicollis	87.20	0.00e+00	1886.00
IUUC-Fox-037788	Fusarium oxysporum	37.73	5.00e-94	339.00
IUUC-Fso-038088	Fusarium solani	36.38	3.00e-91	330.00
IUUC-Gmo-039254	Gadus morhua	65.83	0.00e+00	1210.00
IUUC-Ggr-039941	Gaeumannomyces graminis	33.22	3.00e-82	300.00
IUUC-Gga-040310	Gallus gallus	86.74	0.00e+00	1874.00
IUUC-Gac-042054	Gasterosteus aculeatus	68.49	0.00e+00	1277.00
IUUC-Gma-042836	Glycine max	30.66	7.00e-107	382.00
IUUC-Ggo-045031	Gorilla gorilla	92.27	0.00e+00	1958.00
IUUC-Hsa-045880	Homo sapiens	92.17	0.00e+00	1957.00
IUUC-Hvu-047770	Hordeum vulgare	47.55	3.00e-104	372.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	79.53	0.00e+00	637.00
IUUC-Kpa-049307	Komagataella pastoris	36.52	3.00e-65	243.00
IUUC-Lch-050403	Latimeria chalumnae	80.35	0.00e+00	1650.00
IUUC-Lpe-051428	Leersia perrieri	46.40	6.00e-97	348.00
IUUC-Loc-052218	Lepisosteus oculatus	80.06	0.00e+00	1681.00
IUUC-Lma-053096	Leptosphaeria maculans	38.79	1.00e-81	298.00
IUUC-Laf-054162	Loxodonta africana	86.48	0.00e+00	1635.00
IUUC-Mcc-055127	Macaca mulatta	91.99	0.00e+00	1953.00
IUUC-Meu-056187	Macropus eugenii	81.74	3.00e-105	376.00
IUUC-Mor-057021	Magnaporthe oryzae	34.67	8.00e-80	292.00
IUUC-Mpo-057570	Magnaporthe poae	36.24	7.00e-76	279.00
IUUC-Mtr-058154	Medicago truncatula	30.51	5.00e-108	385.00
IUUC-Mla-059124	Melampsora laricipopulina	48.28	6.00e-103	367.00
IUUC-Mga-059581	Meleagris gallopavo	86.30	0.00e+00	1855.00
IUUC-Mvi-060445	Microbotryum violaceum	38.22	1.00e-106	381.00
IUUC-Mmr-061360	Microcebus murinus	87.64	0.00e+00	1801.00
IUUC-Mdo-062194	Monodelphis domestica	83.45	0.00e+00	1864.00
IUUC-Mmu-064189	Mus musculus	89.69	0.00e+00	1927.00
IUUC-Mac-065275	Musa acuminata	50.61	1.00e-111	397.00
IUUC-Mpu-066439	Mustela putorius furo	90.00	0.00e+00	1878.00
IUUC-Mlu-068228	Myotis lucifugus	87.65	0.00e+00	1867.00
IUUC-Nfi-068280	Neosartorya fischeri	39.28	7.00e-81	295.00
IUUC-Ncr-068869	Neurospora crassa	36.19	7.00e-85	309.00
IUUC-Nle-069687	Nomascus leucogenys	91.92	0.00e+00	1904.00
IUUC-Opr-070592	Ochotona princeps	73.79	2.00e-119	423.00
IUUC-Ont-071836	Oreochromis niloticus	77.26	0.00e+00	1640.00
IUUC-Oan-072800	Ornithorhynchus anatinus	87.57	0.00e+00	1879.00
IUUC-Ocu-074587	Oryctolagus cuniculus	91.53	0.00e+00	1960.00
IUUC-Oba-075006	Oryza barthii	48.66	7.00e-108	385.00
IUUC-Obr-076133	Oryza brachyantha	48.66	5.00e-108	385.00
IUUC-Ogl-077003	Oryza glaberrima	48.66	9.00e-108	385.00
IUUC-Ogu-078947	Oryza glumaepatula	48.66	1.00e-107	384.00
IUUC-Olo-080475	Oryza longistaminata	48.66	7.00e-108	385.00
IUUC-Ome-081342	Oryza meridionalis	45.66	2.00e-95	343.00
IUUC-Oni-082385	Oryza nivara	48.66	8.00e-108	385.00
IUUC-Opu-083176	Oryza punctata	48.90	4.00e-108	386.00
IUUC-Oru-084554	Oryza rufipogon	45.66	5.00e-95	342.00
IUUC-Osa-085355	Oryza sativa	48.66	7.00e-108	385.00
IUUC-Ola-087209	Oryzias latipes	76.61	0.00e+00	1600.00
IUUC-Olu-087699	Ostreococcus lucimarinus	43.13	2.00e-87	315.00
IUUC-Oga-088776	Otolemur garnettii	87.38	0.00e+00	1793.00
IUUC-Ptr-091273	Pan troglodytes	92.17	0.00e+00	1957.00
IUUC-Pan-091981	Papio anubis	92.08	0.00e+00	1956.00
IUUC-Psi-093203	Pelodiscus sinensis	85.94	0.00e+00	1627.00
IUUC-Pma-094738	Petromyzon marinus	65.12	0.00e+00	1329.00
IUUC-Pno-095132	Phaeosphaeria nodorum	34.92	4.00e-58	219.00
IUUC-Ppa-095682	Physcomitrella patens	37.04	2.00e-111	397.00
IUUC-Pfo-097511	Poecilia formosa	77.07	0.00e+00	1639.00
IUUC-Pab-098634	Pongo abelii	89.05	0.00e+00	1873.00
IUUC-Pop-099574	Populus trichocarpa	42.27	2.00e-96	347.00
IUUC-Pca-100987	Procavia capensis	84.32	0.00e+00	850.00
IUUC-Ppe-102040	Prunus persica	37.44	1.00e-96	348.00
IUUC-Pva-103034	Pteropus vampyrus	87.22	0.00e+00	1791.00
IUUC-Pgr-103513	Puccinia graminis	39.18	1.00e-107	384.00
IUUC-Ptt-103967	Puccinia triticina	41.12	3.00e-95	343.00
IUUC-Pte-104105	Pyrenophora teres	34.43	3.00e-82	300.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	37.80	3.00e-80	293.00
IUUC-Rno-105380	Rattus norvegicus	88.19	0.00e+00	1665.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.91	2.00e-68	254.00
IUUC-Sha-107108	Sarcophilus harrisii	80.31	0.00e+00	1721.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	42.96	3.00e-95	343.00
IUUC-Spo-108097	Schizosaccharomyces pombe	44.36	3.00e-94	340.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	29.74	2.00e-84	307.00
IUUC-Smo-109537	Selaginella moellendorffii	37.38	2.00e-106	380.00
IUUC-Sit-110457	Setaria italica	48.53	4.00e-100	359.00
IUUC-Sly-111362	Solanum lycopersicum	36.27	4.00e-101	362.00
IUUC-Sar-113687	Sorex araneus	82.47	0.00e+00	917.00
IUUC-Sbi-113882	Sorghum bicolor	47.30	6.00e-97	348.00
IUUC-Sre-115038	Sporisorium reilianum	44.47	2.00e-98	354.00
IUUC-Ssc-116168	Sus scrofa	86.43	0.00e+00	802.00
IUUC-Tgu-116729	Taeniopygia guttata	86.84	0.00e+00	1867.00
IUUC-Tru-118068	Takifugu rubripes	75.97	0.00e+00	1600.00
IUUC-Tsy-118942	Tarsius syrichta	89.64	0.00e+00	687.00
IUUC-Tni-120732	Tetraodon nigroviridis	74.66	0.00e+00	1539.00
IUUC-Tca-121737	Theobroma cacao	37.58	5.00e-107	382.00
IUUC-Tre-121892	Trichoderma reesei	36.94	9.00e-91	328.00
IUUC-Tvi-122354	Trichoderma virens	35.88	1.00e-91	331.00
IUUC-Tae-125466	Triticum aestivum	47.30	6.00e-104	372.00
IUUC-Tme-127102	Tuber melanosporum	36.24	4.00e-93	336.00
IUUC-Tbe-127351	Tupaia belangeri	78.73	0.00e+00	1469.00
IUUC-Ttr-129061	Tursiops truncatus	90.15	0.00e+00	1888.00
IUUC-Uma-129343	Ustilago maydis	44.47	4.00e-99	356.00
IUUC-Vda-129748	Verticillium dahliae	38.82	3.00e-81	296.00
IUUC-Vvi-131234	Vitis vinifera	35.19	4.00e-103	369.00
IUUC-Xtr-132094	Xenopus tropicalis	83.18	0.00e+00	1746.00
IUUC-Xma-133923	Xiphophorus maculatus	77.16	0.00e+00	1639.00
IUUC-Yli-134496	Yarrowia lipolytica	40.16	6.00e-91	328.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence