iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049259

Ensembl Protein ID

CAY71399

UniProt Accession

C4R724; C4R724_KOMPG

Genbank Protein ID

CAY71399.1

Protein Name

Deubiquitinating enzyme anchored to the outer mitochondrial membrane

Genbank Nucleotide ID

FN392322

Gene Name

PAS_chr4_0174

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr4_0174	CAY71399	CAY71399

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.80e-39	132.0	89	676

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...................kkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkke 80
           tGl N    C+ NS++Q+L+++p l  +l++                   + +++++ ++ + p+++l ++l  l+++l+   ++++++s  ++l++l+k+
   Q: 89   TGLINATVDCFANSTVQALASLPGLNVYLNDffstqsalgklledrrsneEPHNDTRSSDLSVPSTPLHEALSILLSQLQetIYERRSISVWSFLNVLEKI 189
           7*****************************999888888877655544433333333333367777*************97788999************** PP
   S: 81   aeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpgke 180
            ++  + +q+Da+E+l+ +l++le+e  +     ++             +ee  + +  s+ +  F     +q++  ec+ +s   ++ +  +slp p+k 
   Q: 190  FNSRISKSQHDAHELLQLILETLEKEYVS-----VQ--------LFIGVNEELFNDSPVSIPQFPFSSLSINQLRSVECGGSSsLGFDHMAIYSLPTPRKP 277
           *99889********************922.....11........23333566677778899999***************9999799**************9 PP
   S: 181  etkkeslqdcLesftkeeelegenkyycekck........................................................kkqeaekklklkk 225
                sl d++++  ++e +eg   y+c kc+                                                         k++  + ++l k
   Q: 278  FI---SLPDLIKE-NQREVIEG---YNCVKCNvlfcidvlskspdptpterenlkqlkklnvtlkinddlppslqafvdqtckrykyqLKSTLIRNHGLAK 371
           77...9***9987.799****9...99*****999***********99999999999999999999999999999999888888877645559******** PP
   S: 226  lPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts........................................................... 267
            P++L +hL+R  f ++q +r+ ++ +++  l Ld+++   +                                                           
   Q: 372  PPKILPIHLSRSIFLQSQAVRNSCKVEFDEILALDINESILEeaqkfideklkeaiqdakerkpidnnssetlppnllftedekhvgieepmfvenagqds 472
           **************999888766655555555588887554457778887888888777777777777777777777777777777777777776666666 PP
   S: 268  .................peekqke.....................kkkYeLiavvvHsGslssGHYvayvkn............................. 301
                            +     +                     k++Y+L av++H+Gs++ GHY +y ++                             
   Q: 473  edeslssnehiessntvT-----NadnesknlessakvesetsikKCTYKLQAVICHQGSHRIGHYECYRRKphyyktstsneflsdvpellfkapaeeta 568
           666666555555555550.....0555555566666666666676******************************************************** PP
   S: 302  ..........................................................................ekgkWllfdDskVtevkeeevleetgs 328
                                                                                      k+ +++++Dsk+te k e+vl++ + 
   Q: 569  gpppetplsdpspevdesnqdipsdavkspessgsrfrrrmssiismpklnddnspanssdqqskptrklvsssVKNPFWKISDSKITEYKLEDVLKD-SG 668
           *********************************************999999999999999988888877777655777*******************5.58 PP
   S: 329  taYvlfYk 336
            aY+lfY+
   Q: 669  AAYMLFYE 676
           9******8 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MDLEETLSNH LTNFLFRSSP QHPSLIIAQP STYTFQTSPV VQWLSKRKFS SLLTLALLSL 60
SYYIIAPSIP CLNREPRGMF KKRPDKTTTG LINATVDCFA NSTVQALASL PGLNVYLNDF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACTTGG AAGAAACGTT ATCCAACCAT CTAACAAATT TCTTATTCAG ATCTTCTCCA 60
CAGCATCCCA GTTTAATTAT TGCTCAGCCC TCCACGTATA CTTTTCAAAC ATCACCAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ppa:PAS_chr4_0174

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007955	Ashbya gossypii	31.78	2.00e-41	161.00
IUUC-Cgl-026463	Colletotrichum gloeosporioides	26.10	3.00e-19	87.80
IUUC-Dse-031517	Dothistroma septosporum	36.03	6.00e-16	77.00
IUUC-Ggr-039945	Gaeumannomyces graminis	31.17	1.00e-12	66.20
IUUC-Pno-094802	Phaeosphaeria nodorum	25.54	6.00e-16	76.60
IUUC-Pte-104416	Pyrenophora teres	26.23	4.00e-18	84.00
IUUC-Pyt-104503	Pyrenophora triticirepentis	25.99	5.00e-18	84.00
IUUC-Sce-106365	Saccharomyces cerevisiae	31.39	1.00e-32	132.00
IUUC-Tvi-122428	Trichoderma virens	27.48	3.00e-20	91.30
IUUC-Tme-126993	Tuber melanosporum	26.76	2.00e-22	98.60
IUUC-Yli-134426	Yarrowia lipolytica	30.87	1.00e-29	122.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence