iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aor-010027

Ensembl Protein ID

BAE63047

UniProt Accession

Q2U5W8; PPIL2_ASPOR

Genbank Protein ID

BAE63047.1

Protein Name

Peptidyl-prolyl cis-trans isomerase-like 2; Cyclophilin-60; Cyclophilin-like protein Cyp-60; RING-type E3 ubiquitin transferase isomerase-like 2; Rotamase

Genbank Nucleotide ID

AP007166

Gene Name

cyp8; AO090120000480

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AO090120000480	BAE63047	BAE63047

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.90e-12	45.8	43	101

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 7    lCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliq 66
            C++sl+++ +Pv++psG  +d ++I  w+++ gk +Pv+++pl+++dl+  +  ++   
   Q: 43   FCSLSLQPFAHPVCTPSGTIFDLTNILPWIKKHGK-NPVDGTPLKNSDLIKLNIAKNESG 101
           6*********************************9.**************9988887655 PP

Organism

Aspergillus oryzae

Functional Description
(View)

May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.

Protein Sequence
(Fasta)

MGKGSKQITH SEWASGDSYS ASAGAGGGKG GDNAPFKRLP FNFCSLSLQP FAHPVCTPSG 60
TIFDLTNILP WIKKHGKNPV DGTPLKNSDL IKLNIAKNES GDYVDPVTYK VLTDNTHIVA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAAAG GTCAGTTTAG TGAAATAACG TGCTAGGCTA CTTGATAAAT ATAACTTAAT 60
TGCTAACAGA CCCTTTGCCT CGTAGGGACG GATAAGCTTT ATGTATGATA CACCTCATTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0413--Isomerase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0697--Rotamase
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR029000--Cyclophilin-like_dom
IPR024936--Cyclophilin-type_PPIase
IPR020892--Cyclophilin-type_PPIase_CS
IPR002130--Cyclophilin-type_PPIase_dom
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00170--CSA_PPIASE_1
PS50072--CSA_PPIASE_2
PS51698--U_BOX

Pfam

PF00160--Pro_isomerase

PRINTS

PR00153--CSAPPISMRASE

SMART

SM00504--Ubox

Gene Ontology

GO:0005634--C:nucleus
GO:0003755--F:peptidyl-prolyl cis-trans isomerase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006457--P:protein folding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000982	Aegilops tauschii	48.89	3.00e-38	151.00
IUUC-Aml-002351	Ailuropoda melanoleuca	41.12	4.00e-106	376.00
IUUC-Atr-002724	Amborella trichopoda	37.84	9.00e-92	328.00
IUUC-Apl-003515	Anas platyrhynchos	42.13	6.00e-99	352.00
IUUC-Aca-004802	Anolis carolinensis	42.88	3.00e-107	380.00
IUUC-Aly-005928	Arabidopsis lyrata	39.05	5.00e-84	303.00
IUUC-Ath-007574	Arabidopsis thaliana	38.66	6.00e-78	283.00
IUUC-Acl-008183	Aspergillus clavatus	80.07	0.00e+00	770.00
IUUC-Afl-008382	Aspergillus flavus	98.95	0.00e+00	961.00
IUUC-Afu-008952	Aspergillus fumigatus	80.62	0.00e+00	793.00
IUUC-Ani-009146	Aspergillus nidulans	77.66	0.00e+00	814.00
IUUC-Ang-009743	Aspergillus niger	79.45	0.00e+00	776.00
IUUC-Ate-010569	Aspergillus terreus	84.44	0.00e+00	898.00
IUUC-Ame-010783	Astyanax mexicanus	43.28	4.00e-107	379.00
IUUC-Bgr-012172	Blumeria graminis	47.53	3.00e-117	413.00
IUUC-Bta-012459	Bos taurus	41.55	2.00e-103	367.00
IUUC-Bci-013693	Botrytis cinerea	54.88	4.00e-151	526.00
IUUC-Bdi-014623	Brachypodium distachyon	40.11	7.00e-91	326.00
IUUC-Bol-015781	Brassica oleracea	39.64	2.00e-87	314.00
IUUC-Bra-016624	Brassica rapa	39.84	6.00e-87	313.00
IUUC-Cel-018328	Caenorhabditis elegans	39.24	1.00e-88	318.00
IUUC-Cja-019427	Callithrix jacchus	42.88	4.00e-104	369.00
IUUC-Cfa-020829	Canis familiaris	43.60	4.00e-110	390.00
IUUC-Cpo-022189	Cavia porcellus	43.82	6.00e-109	385.00
IUUC-Cre-022723	Chlamydomonas reinhardtii	51.37	7.00e-45	173.00
IUUC-Csa-024212	Chlorocebus sabaeus	44.19	3.00e-109	386.00
IUUC-Cin-025720	Ciona intestinalis	41.79	1.00e-100	358.00
IUUC-Csv-026137	Ciona savignyi	43.98	8.00e-94	335.00
IUUC-Cgl-026532	Colletotrichum gloeosporioides	53.51	5.00e-148	515.00
IUUC-Cne-026830	Cryptococcus neoformans	41.69	2.00e-105	374.00
IUUC-Dre-028561	Danio rerio	41.15	7.00e-100	355.00
IUUC-Dno-029029	Dasypus novemcinctus	44.76	7.00e-57	213.00
IUUC-Dor-030544	Dipodomys ordii	50.00	1.00e-38	152.00
IUUC-Dse-031506	Dothistroma septosporum	59.59	2.00e-162	563.00
IUUC-Dme-032058	Drosophila melanogaster	37.13	4.00e-92	330.00
IUUC-Ete-033157	Echinops telfairi	34.51	1.00e-69	254.00
IUUC-Eca-034176	Equus caballus	50.00	1.00e-38	152.00
IUUC-Eeu-034470	Erinaceus europaeus	42.66	3.00e-65	241.00
IUUC-Fca-036571	Felis catus	43.66	4.00e-110	389.00
IUUC-Fal-037613	Ficedula albicollis	42.70	5.00e-108	382.00
IUUC-Fox-037795	Fusarium oxysporum	53.85	7.00e-157	545.00
IUUC-Fso-038213	Fusarium solani	52.85	5.00e-145	506.00
IUUC-Gmo-039609	Gadus morhua	41.71	1.00e-94	338.00
IUUC-Ggr-039825	Gaeumannomyces graminis	54.49	3.00e-145	506.00
IUUC-Gga-041191	Gallus gallus	42.72	7.00e-107	379.00
IUUC-Gac-041524	Gasterosteus aculeatus	46.05	6.00e-101	359.00
IUUC-Gma-042925	Glycine max	46.12	1.00e-45	175.00
IUUC-Ggo-045352	Gorilla gorilla	44.01	3.00e-108	383.00
IUUC-Hsa-045709	Homo sapiens	44.01	4.00e-108	383.00
IUUC-Hvu-047058	Hordeum vulgare	35.00	3.00e-66	244.00
IUUC-Itr-048483	Ictidomys tridecemlineatus	47.55	1.00e-103	367.00
IUUC-Lch-049681	Latimeria chalumnae	46.37	1.00e-95	341.00
IUUC-Lpe-050799	Leersia perrieri	48.18	3.00e-46	177.00
IUUC-Loc-052566	Lepisosteus oculatus	39.32	5.00e-79	286.00
IUUC-Lma-053028	Leptosphaeria maculans	59.27	9.00e-162	561.00
IUUC-Laf-054547	Loxodonta africana	44.01	3.00e-106	377.00
IUUC-Mcc-054753	Macaca mulatta	47.79	2.00e-103	367.00
IUUC-Meu-056855	Macropus eugenii	32.68	6.00e-35	139.00
IUUC-Mor-056941	Magnaporthe oryzae	54.13	4.00e-136	476.00
IUUC-Mpo-057306	Magnaporthe poae	52.68	1.00e-150	524.00
IUUC-Mtr-058349	Medicago truncatula	42.15	8.00e-89	319.00
IUUC-Mla-058842	Melampsora laricipopulina	40.70	2.00e-106	377.00
IUUC-Mga-060099	Meleagris gallopavo	39.25	8.00e-97	345.00
IUUC-Mvi-060413	Microbotryum violaceum	40.04	4.00e-100	357.00
IUUC-Mmr-061530	Microcebus murinus	43.51	5.00e-109	386.00
IUUC-Mdo-062668	Monodelphis domestica	46.77	4.00e-102	363.00
IUUC-Mmu-063871	Mus musculus	43.26	3.00e-108	383.00
IUUC-Mac-064559	Musa acuminata	49.10	8.00e-48	182.00
IUUC-Mpu-065919	Mustela putorius furo	42.67	5.00e-105	372.00
IUUC-Mlu-067846	Myotis lucifugus	37.76	3.00e-94	337.00
IUUC-Nfi-068507	Neosartorya fischeri	79.56	0.00e+00	746.00
IUUC-Ncr-068805	Neurospora crassa	50.99	2.00e-120	424.00
IUUC-Nle-070125	Nomascus leucogenys	40.19	1.00e-94	338.00
IUUC-Opr-070486	Ochotona princeps	40.29	6.00e-78	282.00
IUUC-Ont-071597	Oreochromis niloticus	42.22	2.00e-104	370.00
IUUC-Oan-073117	Ornithorhynchus anatinus	44.87	8.00e-31	126.00
IUUC-Ocu-074411	Oryctolagus cuniculus	43.26	9.00e-104	368.00
IUUC-Oba-075040	Oryza barthii	48.18	3.00e-46	177.00
IUUC-Obr-076727	Oryza brachyantha	46.82	2.00e-45	175.00
IUUC-Ogl-077605	Oryza glaberrima	48.18	3.00e-46	177.00
IUUC-Ogu-078177	Oryza glumaepatula	48.18	3.00e-46	177.00
IUUC-Oin-079549	Oryza indica	52.74	2.00e-45	174.00
IUUC-Olo-081090	Oryza longistaminata	48.18	2.00e-46	178.00
IUUC-Ome-081979	Oryza meridionalis	48.18	3.00e-46	177.00
IUUC-Oni-082819	Oryza nivara	48.18	3.00e-46	177.00
IUUC-Opu-083212	Oryza punctata	52.74	2.00e-45	174.00
IUUC-Oru-084412	Oryza rufipogon	48.18	3.00e-46	177.00
IUUC-Osa-085431	Oryza sativa	48.00	1.00e-30	123.00
IUUC-Ola-086602	Oryzias latipes	46.31	7.00e-98	348.00
IUUC-Olu-087682	Ostreococcus lucimarinus	41.30	1.00e-85	308.00
IUUC-Oga-088999	Otolemur garnettii	42.02	2.00e-98	351.00
IUUC-Oar-089338	Ovis aries	38.18	2.00e-81	294.00
IUUC-Ptr-091185	Pan troglodytes	44.01	3.00e-108	383.00
IUUC-Pan-092321	Papio anubis	43.97	9.00e-110	388.00
IUUC-Psi-094018	Pelodiscus sinensis	41.59	1.00e-54	204.00
IUUC-Pma-094111	Petromyzon marinus	40.84	3.00e-74	270.00
IUUC-Pno-094782	Phaeosphaeria nodorum	57.29	9.00e-165	571.00
IUUC-Ppa-095335	Physcomitrella patens	41.90	2.00e-49	188.00
IUUC-Pfo-097393	Poecilia formosa	42.94	4.00e-106	376.00
IUUC-Pab-098263	Pongo abelii	40.07	1.00e-92	331.00
IUUC-Pop-099316	Populus trichocarpa	42.99	1.00e-83	302.00
IUUC-Pca-100387	Procavia capensis	55.56	2.00e-39	155.00
IUUC-Ppe-101275	Prunus persica	49.10	6.00e-46	176.00
IUUC-Pva-102150	Pteropus vampyrus	45.69	5.00e-91	326.00
IUUC-Pgr-103378	Puccinia graminis	42.74	6.00e-113	399.00
IUUC-Ptt-103908	Puccinia triticina	42.91	6.00e-102	362.00
IUUC-Pte-104248	Pyrenophora teres	57.99	7.00e-168	582.00
IUUC-Pyt-104645	Pyrenophora triticirepentis	58.51	3.00e-170	590.00
IUUC-Rno-105162	Rattus norvegicus	43.82	1.00e-110	391.00
IUUC-Sha-107123	Sarcophilus harrisii	40.88	2.00e-43	168.00
IUUC-Sja-107828	Schizosaccharomyces japonicus	44.96	4.00e-117	412.00
IUUC-Spo-108368	Schizosaccharomyces pombe	46.10	7.00e-126	442.00
IUUC-Smo-109102	Selaginella moellendorffii	37.35	5.00e-91	326.00
IUUC-Sit-110821	Setaria italica	47.73	7.00e-46	176.00
IUUC-Sly-111803	Solanum lycopersicum	34.78	8.00e-73	266.00
IUUC-Stu-112730	Solanum tuberosum	34.97	2.00e-77	281.00
IUUC-Sar-113618	Sorex araneus	43.82	3.00e-106	377.00
IUUC-Sbi-114487	Sorghum bicolor	48.18	2.00e-45	175.00
IUUC-Sre-115009	Sporisorium reilianum	41.46	5.00e-97	346.00
IUUC-Ssc-115984	Sus scrofa	43.10	9.00e-107	378.00
IUUC-Tgu-117410	Taeniopygia guttata	42.32	5.00e-107	379.00
IUUC-Tru-118537	Takifugu rubripes	42.51	7.00e-103	365.00
IUUC-Tsy-119318	Tarsius syrichta	34.28	2.00e-38	151.00
IUUC-Tni-120514	Tetraodon nigroviridis	44.66	5.00e-75	273.00
IUUC-Tca-121620	Theobroma cacao	39.65	1.00e-85	308.00
IUUC-Tre-121904	Trichoderma reesei	49.30	1.00e-123	434.00
IUUC-Tvi-122585	Trichoderma virens	54.44	2.00e-130	457.00
IUUC-Tae-125342	Triticum aestivum	34.38	3.00e-64	237.00
IUUC-Tur-126759	Triticum urartu	48.03	2.00e-36	145.00
IUUC-Tme-126960	Tuber melanosporum	52.51	1.00e-153	534.00
IUUC-Tbe-128038	Tupaia belangeri	48.72	5.00e-37	147.00
IUUC-Ttr-129173	Tursiops truncatus	33.90	1.00e-71	261.00
IUUC-Uma-129595	Ustilago maydis	38.25	5.00e-89	319.00
IUUC-Vda-130012	Verticillium dahliae	54.31	8.00e-151	525.00
IUUC-Vpa-130129	Vicugna pacos	50.00	9.00e-39	152.00
IUUC-Vvi-131156	Vitis vinifera	42.07	1.00e-53	202.00
IUUC-Xtr-132807	Xenopus tropicalis	42.73	2.00e-96	344.00
IUUC-Xma-133563	Xiphophorus maculatus	49.36	2.00e-37	148.00
IUUC-Yli-134361	Yarrowia lipolytica	34.32	7.00e-53	199.00
IUUC-Zma-135759	Zea mays	49.51	6.00e-45	173.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence