iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071847

Ensembl Protein ID

ENSONIP00000018574.1

UniProt Accession

I3KBS9; I3KBS9_ORENI

Genbank Protein ID

ENSONIP00000018574

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01014299

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000014753.1	ENSONIT00000018591.1	ENSONIP00000018574.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.30e-112	375.4	245	872

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++l+ ++  +ln +np ++kge++++++++++++w++++ +v pr ++++++++a++f gy+
   Q: 245  CGLTNLGNTCFMNSALQCLSNTPPLTEYFLQnSYVDELNFTNPLGMKGEIAEAYADVIKQMWSGRHYSVVPRVFKTKVGHFASQFLGYQ 333
           7******************************999******************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           q+D+qE+l+flld+l+e+l++ knk++ e++++d ++ ++    a++++ ++n+s+i+d+F+g +ks+++c+ec++vs++++pf++ls+
   Q: 334  QHDSQELLSFLLDGLHEDLNRVKNKEYIELRDADGRQDQEVaeeAWRNHLRRNDSVIVDTFHGLFKSTLVCPECHKVSVTFDPFCYLSV 422
           ****************************9999885444433555********************************************* PP
   S: 175  pvpgkeetkke.............................................................................. 185
           p+p ++e+ +e                                                                              
   Q: 423  PLPVSKERVMEvffvsldpyakpvqlhskrckagkvsdlcsalsemtsvpptqmvvadvfnhrfykiynmgeslsaildrddifvyels 511
           ******99999****************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 512  vleeqpeeqvllalylrershyrdygsgggsygtslfghplllnvprsscsqealynlflqrlaryvrlpdpsedsaddidpseqsggp 600
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 601  aeadgsseppaeqphkpteeeneedkqeeacspsppanehpakrrachvrrkrlfsiqavnsngttergmgeggsavsfssqpyvaidw 689
           ***************************************************************************************** PP
   S: 186  ................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfsee 242
                                           +lq+c+e ft+ e+le+en ++c+ c ++q a+kkl+l++lPevLi+hLkRfs+++ 
   Q: 690  epdmkkrfyneneaekyvkdpsmevpqqhmtvQLQQCIELFTTVETLEEENPWSCPGCAQHQLATKKLDLWSLPEVLIIHLKRFSYTK- 777
           ************************************************************************************8866. PP
   S: 243  qksrekinkkvefple.Ldlspfctspeekqke.kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgs 328
              rek+++ vefpl+ Ld s f+ +++ +++e + +Y+Liav +H+G+l+ GHY++y+kn++++ W++fdDskVt  +e+++++   s
   Q: 778  -FTREKLDSIVEFPLRdLDFSGFLLRKTLSSEEpPSRYDLIAVSNHYGGLRDGHYTTYAKNKDNGqWYYFDDSKVTYATEDQIVT---S 862
           .7999*****************999988877665899************************66555*******************...* PP
   S: 329  taYvlfYkrr 338
            aYvlfY+r+
   Q: 863  AAYVLFYQRQ 872
           ********96 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MTANSRCSAA EPPGLETQRR EIESLLRECE LRAGESWYVV DRRWFDQWKE FVETGDQNST 60
SFPGQIDNAE LFEDLDSYHL KDRLVEDEDF VLVPAEAWHK LLAWYGIADD QPPLERKVVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGCCA ACAGCCGCTG CTCCGCCGCG GAGCCCCCGG GCCTGGAGAC CCAGCGACGG 60
GAGATCGAGT CTCTTCTGCG GGAGTGCGAG CTCCGCGCTG GGGAGAGCTG GTGAGAGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001760	Ailuropoda melanoleuca	58.49	0.00e+00	1019.00
IUUC-Atr-002991	Amborella trichopoda	33.44	2.00e-127	450.00
IUUC-Aca-004532	Anolis carolinensis	61.66	0.00e+00	1030.00
IUUC-Ame-011858	Astyanax mexicanus	73.67	0.00e+00	830.00
IUUC-Bta-013284	Bos taurus	60.14	0.00e+00	1033.00
IUUC-Cel-018257	Caenorhabditis elegans	35.32	5.00e-95	342.00
IUUC-Cja-019746	Callithrix jacchus	58.12	0.00e+00	996.00
IUUC-Cfa-020134	Canis familiaris	59.02	0.00e+00	1033.00
IUUC-Cpo-022535	Cavia porcellus	55.18	0.00e+00	967.00
IUUC-Csa-023828	Chlorocebus sabaeus	58.09	0.00e+00	1011.00
IUUC-Dre-027398	Danio rerio	76.11	0.00e+00	909.00
IUUC-Dno-028853	Dasypus novemcinctus	60.80	0.00e+00	910.00
IUUC-Dor-030384	Dipodomys ordii	55.33	0.00e+00	965.00
IUUC-Eca-033271	Equus caballus	60.07	0.00e+00	1011.00
IUUC-Fca-036012	Felis catus	58.74	0.00e+00	1021.00
IUUC-Gmo-038697	Gadus morhua	69.21	0.00e+00	810.00
IUUC-Gac-042574	Gasterosteus aculeatus	75.85	0.00e+00	1262.00
IUUC-Gma-042669	Glycine max	37.04	4.00e-112	399.00
IUUC-Hsa-046551	Homo sapiens	58.09	0.00e+00	1011.00
IUUC-Itr-048915	Ictidomys tridecemlineatus	55.75	0.00e+00	955.00
IUUC-Laf-054561	Loxodonta africana	58.89	0.00e+00	1023.00
IUUC-Mcc-054881	Macaca mulatta	57.97	0.00e+00	1008.00
IUUC-Meu-056749	Macropus eugenii	68.52	0.00e+00	752.00
IUUC-Mmr-061400	Microcebus murinus	59.00	0.00e+00	1025.00
IUUC-Mmu-063241	Mus musculus	56.67	0.00e+00	985.00
IUUC-Mpu-066507	Mustela putorius furo	59.62	0.00e+00	1035.00
IUUC-Mlu-066961	Myotis lucifugus	57.55	0.00e+00	961.00
IUUC-Nle-069284	Nomascus leucogenys	58.09	0.00e+00	1011.00
IUUC-Oan-073387	Ornithorhynchus anatinus	61.97	0.00e+00	1046.00
IUUC-Ocu-074066	Oryctolagus cuniculus	57.88	0.00e+00	1002.00
IUUC-Ola-086500	Oryzias latipes	74.05	0.00e+00	1241.00
IUUC-Oga-088424	Otolemur garnettii	59.59	0.00e+00	1032.00
IUUC-Oar-089732	Ovis aries	59.48	0.00e+00	1003.00
IUUC-Pan-092292	Papio anubis	58.09	0.00e+00	1010.00
IUUC-Pfo-096414	Poecilia formosa	86.99	0.00e+00	1035.00
IUUC-Pab-098779	Pongo abelii	54.26	0.00e+00	880.00
IUUC-Pop-099866	Populus trichocarpa	32.76	6.00e-122	432.00
IUUC-Pca-100851	Procavia capensis	65.66	0.00e+00	669.00
IUUC-Pva-103244	Pteropus vampyrus	58.73	0.00e+00	1000.00
IUUC-Ptt-103847	Puccinia triticina	42.30	1.00e-65	245.00
IUUC-Rno-105100	Rattus norvegicus	56.79	0.00e+00	991.00
IUUC-Sce-106170	Saccharomyces cerevisiae	34.05	1.00e-62	235.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	37.12	2.00e-81	297.00
IUUC-Spo-108291	Schizosaccharomyces pombe	33.67	8.00e-77	282.00
IUUC-Sly-111746	Solanum lycopersicum	34.38	1.00e-130	461.00
IUUC-Stu-112671	Solanum tuberosum	40.22	1.00e-120	427.00
IUUC-Ssc-116345	Sus scrofa	59.69	0.00e+00	1051.00
IUUC-Tru-117788	Takifugu rubripes	78.76	0.00e+00	1295.00
IUUC-Tsy-119414	Tarsius syrichta	54.38	0.00e+00	724.00
IUUC-Tni-120799	Tetraodon nigroviridis	75.47	0.00e+00	952.00
IUUC-Tvi-122422	Trichoderma virens	43.38	3.00e-59	224.00
IUUC-Tae-124994	Triticum aestivum	40.19	3.00e-122	432.00
IUUC-Tbe-128081	Tupaia belangeri	62.29	0.00e+00	666.00
IUUC-Ttr-128502	Tursiops truncatus	56.79	0.00e+00	951.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence