iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026821

Ensembl Protein ID

AAW41233

UniProt Accession

Q5KN85; Q55YW8; Q5KN85_CRYNJ

Genbank Protein ID

AAW41233.1

Protein Name

Ubiquitin-specific protease, putative

Genbank Nucleotide ID

AE017341

Gene Name

CNA07360

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNA07360	AAW41233	AAW41233

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.30e-98	326.0	951	1309

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaf 98
           tGlkNlgNtCYmNS++QcLs++ ++  ++l+  + +++n+enp ++kgel+k++++l++ lw++k +  sp ++ k++ ++a++f g++q+D+qEfl+f
   Q: 951  TGLKNLGNTCYMNSTIQCLSATYPFSTFFLDgTFARSINKENPLGTKGELAKAWAELLRVLWSEKYEFLSPMTFRKQITHFAPQFLGSDQHDSQEFLSF 1049
           7******************************99****************************************************************** PP
   S: 99   lldqleeelkkeknkpkeeeeeedkselsde.........aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslq 188
           +ld+l+e+l++ k+kp   e+  +++++ ++         ++    ++n+sli+dlFqgq+++++ cl+c+++s++++ f+++slpvp+ ++  k  +q
   Q: 1050 VLDGLHEDLNRVKRKPPPVEMTPEREAMLESappevaserEWAIYRQRNDSLIVDLFQGQYRNRLECLTCHKTSTTYDAFMYMSLPVPSGKT--KVVIQ 1146
           *********99666555544444444444445899999999***********************************************8884..469** PP
   S: 189  dcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekqke............ 274
           +++++f+k+e +e+en++yc++ck +++a+k+l++ +lP+vL ++LkRf+  +++ +  k ++ v fp++ Ldl++++  p  ++              
   Q: 1147 ELIDEFVKAEVMEKENAWYCPRCKTNRRASKTLTIARLPPVLLIQLKRFTT-RDGLFWDKSETPVIFPIRgLDLTRYLPGPAGSSIGsgrqvgpdgtfd 1244
           *************************************************65.6678889********************97766655777888888888 PP
   S: 275  ......kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                 + kY+L++v +H+G+lssGHY+a+vk+ k++W ++ Ds+V + +e++v +   + aY+lfYkr
   Q: 1245 praqvgPFKYDLYGVSNHMGTLSSGHYTAFVKS-KEGWKYCEDSQVMPAQEKDVIS---RPAYILFYKR 1309
           888888***************************.778*******************...********98 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MTRPPSPPSF TGLPLSQLLQ YASDDNGAGS HPPKVWFERA CYNADKAKLA ERKQSKEDMF 60
VSYSRACQSY INVAMHNDWP ETKKKDPQLA ARVKDFKPMY DSFVAKAKAL KEELRHAEAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTCGGC CGCCGTCCCC GCCATCGTTC ACAGGGCTCC CGCTCTCGCA GCTGCTGCAG 60
TACGCCTCGG ACGACAACGG CGCAGGCAGC CACCCGCCCA AAGTATGGTT CGAACGCGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR001763--Rhodanese-like_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cne:CNA07360

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001661	Ailuropoda melanoleuca	40.17	1.00e-75	276.00
IUUC-Apl-003226	Anas platyrhynchos	40.72	8.00e-76	276.00
IUUC-Aca-004936	Anolis carolinensis	39.61	2.00e-73	269.00
IUUC-Ago-007959	Ashbya gossypii	39.36	3.00e-71	261.00
IUUC-Acl-008102	Aspergillus clavatus	37.10	3.00e-68	251.00
IUUC-Afl-008604	Aspergillus flavus	37.63	3.00e-68	251.00
IUUC-Afu-009001	Aspergillus fumigatus	37.47	7.00e-68	250.00
IUUC-Ani-009291	Aspergillus nidulans	37.33	4.00e-67	247.00
IUUC-Ang-009844	Aspergillus niger	36.39	1.00e-66	246.00
IUUC-Aor-010098	Aspergillus oryzae	37.63	3.00e-68	251.00
IUUC-Ate-010585	Aspergillus terreus	36.00	2.00e-65	242.00
IUUC-Ame-011102	Astyanax mexicanus	36.36	5.00e-52	196.00
IUUC-Bta-013008	Bos taurus	40.17	1.00e-75	276.00
IUUC-Cja-019173	Callithrix jacchus	39.89	7.00e-75	273.00
IUUC-Cfa-021243	Canis familiaris	40.17	8.00e-76	276.00
IUUC-Cpo-021522	Cavia porcellus	39.61	6.00e-75	274.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	42.06	2.00e-79	286.00
IUUC-Csa-023616	Chlorocebus sabaeus	39.61	1.00e-74	273.00
IUUC-Cho-024381	Choloepus hoffmanni	34.65	2.00e-54	206.00
IUUC-Cin-025287	Ciona intestinalis	37.20	1.00e-56	213.00
IUUC-Csv-026253	Ciona savignyi	38.39	5.00e-57	214.00
IUUC-Dre-028440	Danio rerio	35.71	1.00e-71	263.00
IUUC-Dno-029039	Dasypus novemcinctus	39.89	5.00e-75	274.00
IUUC-Dor-031053	Dipodomys ordii	35.56	3.00e-63	234.00
IUUC-Dse-031463	Dothistroma septosporum	36.32	2.00e-61	229.00
IUUC-Dme-032089	Drosophila melanogaster	35.13	2.00e-61	229.00
IUUC-Ete-033040	Echinops telfairi	41.63	4.00e-58	218.00
IUUC-Eca-033449	Equus caballus	39.89	1.00e-76	280.00
IUUC-Fca-035794	Felis catus	40.17	8.00e-75	272.00
IUUC-Fal-037322	Ficedula albicollis	41.27	4.00e-77	281.00
IUUC-Gmo-038584	Gadus morhua	36.88	5.00e-70	257.00
IUUC-Gga-041188	Gallus gallus	40.72	8.00e-76	276.00
IUUC-Gac-041850	Gasterosteus aculeatus	39.72	4.00e-73	268.00
IUUC-Ggo-045565	Gorilla gorilla	39.89	4.00e-75	274.00
IUUC-Hsa-046438	Homo sapiens	39.89	5.00e-75	274.00
IUUC-Itr-048883	Ictidomys tridecemlineatus	39.89	3.00e-75	275.00
IUUC-Kpa-049321	Komagataella pastoris	37.70	2.00e-72	265.00
IUUC-Lch-050485	Latimeria chalumnae	41.27	2.00e-78	285.00
IUUC-Loc-052769	Lepisosteus oculatus	39.23	9.00e-73	266.00
IUUC-Lma-053021	Leptosphaeria maculans	37.43	6.00e-67	247.00
IUUC-Laf-053432	Loxodonta africana	39.89	6.00e-75	274.00
IUUC-Mcc-055823	Macaca mulatta	39.61	3.00e-75	275.00
IUUC-Meu-056279	Macropus eugenii	35.81	1.00e-63	235.00
IUUC-Mla-059089	Melampsora laricipopulina	56.76	7.00e-114	403.00
IUUC-Mga-059739	Meleagris gallopavo	40.72	3.00e-75	275.00
IUUC-Mvi-060559	Microbotryum violaceum	55.49	4.00e-121	427.00
IUUC-Mmr-061158	Microcebus murinus	40.17	5.00e-75	274.00
IUUC-Mdo-061801	Monodelphis domestica	40.17	3.00e-75	275.00
IUUC-Mmu-063665	Mus musculus	39.89	1.00e-75	276.00
IUUC-Mpu-066738	Mustela putorius furo	40.17	1.00e-75	276.00
IUUC-Mlu-067307	Myotis lucifugus	39.89	2.00e-75	275.00
IUUC-Nfi-068410	Neosartorya fischeri	36.93	8.00e-68	250.00
IUUC-Nle-069314	Nomascus leucogenys	39.89	3.00e-75	275.00
IUUC-Opr-071096	Ochotona princeps	35.03	2.00e-61	228.00
IUUC-Ont-071545	Oreochromis niloticus	39.44	8.00e-75	273.00
IUUC-Oan-073537	Ornithorhynchus anatinus	39.94	4.00e-73	268.00
IUUC-Ocu-074193	Oryctolagus cuniculus	39.89	3.00e-75	275.00
IUUC-Ola-086622	Oryzias latipes	40.00	8.00e-73	266.00
IUUC-Oga-088271	Otolemur garnettii	39.89	4.00e-75	275.00
IUUC-Oar-090431	Ovis aries	40.17	1.00e-75	276.00
IUUC-Ptr-091339	Pan troglodytes	39.89	3.00e-75	275.00
IUUC-Pan-092266	Papio anubis	39.72	1.00e-70	257.00
IUUC-Psi-093216	Pelodiscus sinensis	36.22	1.00e-63	235.00
IUUC-Pma-094626	Petromyzon marinus	39.51	2.00e-76	277.00
IUUC-Pno-094986	Phaeosphaeria nodorum	34.52	2.00e-48	186.00
IUUC-Pfo-096463	Poecilia formosa	38.89	2.00e-73	268.00
IUUC-Pab-097645	Pongo abelii	39.89	6.00e-75	274.00
IUUC-Pva-103222	Pteropus vampyrus	38.84	3.00e-73	268.00
IUUC-Pgr-103408	Puccinia graminis	50.58	5.00e-95	341.00
IUUC-Ptt-103699	Puccinia triticina	60.78	1.00e-102	366.00
IUUC-Pte-104348	Pyrenophora teres	35.91	7.00e-54	204.00
IUUC-Pyt-104711	Pyrenophora triticirepentis	36.39	2.00e-64	239.00
IUUC-Rno-105510	Rattus norvegicus	40.44	3.00e-76	278.00
IUUC-Sce-106166	Saccharomyces cerevisiae	42.55	2.00e-78	285.00
IUUC-Sha-106879	Sarcophilus harrisii	39.84	1.00e-73	269.00
IUUC-Sja-107836	Schizosaccharomyces japonicus	40.71	9.00e-74	269.00
IUUC-Spo-108065	Schizosaccharomyces pombe	34.70	4.00e-53	200.00
IUUC-Sar-113019	Sorex araneus	39.29	3.00e-74	271.00
IUUC-Sre-115031	Sporisorium reilianum	50.84	8.00e-124	436.00
IUUC-Ssc-116334	Sus scrofa	39.89	4.00e-75	274.00
IUUC-Tgu-117062	Taeniopygia guttata	41.00	4.00e-76	278.00
IUUC-Tru-117908	Takifugu rubripes	39.17	6.00e-73	267.00
IUUC-Tsy-118867	Tarsius syrichta	35.73	2.00e-61	229.00
IUUC-Tni-120206	Tetraodon nigroviridis	39.18	3.00e-71	261.00
IUUC-Tme-127144	Tuber melanosporum	45.78	4.00e-93	334.00
IUUC-Ttr-128580	Tursiops truncatus	40.17	6.00e-76	277.00
IUUC-Uma-129340	Ustilago maydis	53.53	2.00e-119	421.00
IUUC-Vpa-130541	Vicugna pacos	38.78	5.00e-72	264.00
IUUC-Xtr-132161	Xenopus tropicalis	38.67	4.00e-74	271.00
IUUC-Xma-134271	Xiphophorus maculatus	38.61	4.00e-73	268.00
IUUC-Yli-134561	Yarrowia lipolytica	41.80	2.00e-75	275.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence