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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018303
Ensembl Protein ID T26A5.5a
UniProt Accession Q95Q98; Q95Q99; JHD1_CAEEL
Genbank Protein ID CCD63210.1; CCD63211.1
Protein Name JmjC domain-containing histone demethylation protein 1; [Histone-H3]-lysine-36 demethylase 1
Genbank Nucleotide ID FO080366; FO080366
Gene Name jhdm-1; T26A5.5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00020821 T26A5.5a T26A5.5a
WBGene00020821 T26A5.5b T26A5.5b
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
miRTarBasemicroRNARAID2
Post-translational Modifications (PTMs)
dbPAFdbPTMPhospho.ELM
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/SCF/F-box 44.10 5.00e-78 290.00 IUUC-Dme-032039
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code (By similarity). Has a role in regulating lifespan.
 Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code (By similarity). Has a role in regulating lifespan.
Protein Sequence
(Fasta)
MPPKRKSNGK TPANGKKGAK KARKESSSEH EHSASEGEET TGFDKSSLQR CVNFDFEALM 60
NDPSFQHPEF VHTMDPEALN LEFYDKNGLD NPIHFRCDPK RIGMTLPSPD FSVDDVLELV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018303|E3,F-box|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGCCGCCGA AACGGAAATC AAATGGAAAA ACGCCAGCGA ACGGTAAAAA GGGCGCAAAG 60
AAGGCTAGGA AAGAGTCAAG TTCAGAGCAC GAACATAGTG CTTCAGAAGG TGAAGAAACT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018303|E3,F-box|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0223--Dioxygenase
KW-0408--Iron
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0560--Oxidoreductase
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR003347--JmjC_dom
PROSITE

PS51184--JMJC
SMART

SM00558--JmjC
Gene Ontology

GO:0005634--C:nucleus
GO:0051864--F:histone demethylase activity (H3-K36 specific)
GO:0046872--F:metal ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
KEGG cel:CELE_T26A5.5
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001358 Ailuropoda melanoleuca 44.86 4.00e-83 301.00
IUUC-Apl-003787 Anas platyrhynchos 46.28 3.00e-81 295.00
IUUC-Aca-004247 Anolis carolinensis 44.55 1.00e-81 297.00
IUUC-Ago-007912 Ashbya gossypii 35.38 4.00e-40 157.00
IUUC-Acl-008303 Aspergillus clavatus 38.38 7.00e-56 211.00
IUUC-Afl-008579 Aspergillus flavus 33.68 5.00e-23 102.00
IUUC-Afu-008903 Aspergillus fumigatus 37.13 5.00e-57 215.00
IUUC-Ani-009279 Aspergillus nidulans 38.57 3.00e-57 216.00
IUUC-Ang-009645 Aspergillus niger 39.48 1.00e-56 214.00
IUUC-Aor-010233 Aspergillus oryzae 37.06 1.00e-57 217.00
IUUC-Ate-010345 Aspergillus terreus 37.58 1.00e-59 224.00
IUUC-Ame-011463 Astyanax mexicanus 42.68 2.00e-81 296.00
IUUC-Bta-013531 Bos taurus 44.86 1.00e-83 304.00
IUUC-Cja-019030 Callithrix jacchus 43.30 1.00e-73 270.00
IUUC-Cfa-020857 Canis familiaris 44.86 2.00e-83 303.00
IUUC-Cpo-021967 Cavia porcellus 44.86 3.00e-83 302.00
IUUC-Cre-022782 Chlamydomonas reinhardtii 24.66 4.40e-01 28.10
IUUC-Csa-023210 Chlorocebus sabaeus 44.55 6.00e-83 301.00
IUUC-Cho-024541 Choloepus hoffmanni 37.76 3.00e-52 199.00
IUUC-Cin-025140 Ciona intestinalis 44.85 1.00e-69 256.00
IUUC-Csv-025861 Ciona savignyi 41.85 3.00e-75 275.00
IUUC-Cne-026797 Cryptococcus neoformans 34.28 8.00e-45 174.00
IUUC-Cme-027118 Cyanidioschyzon merolae 32.10 7.00e-40 157.00
IUUC-Dre-027763 Danio rerio 44.58 6.00e-80 291.00
IUUC-Dno-030034 Dasypus novemcinctus 44.01 2.00e-82 299.00
IUUC-Dor-030736 Dipodomys ordii 44.24 2.00e-79 290.00
IUUC-Dse-031402 Dothistroma septosporum 41.64 5.00e-54 206.00
IUUC-Dme-032039 Drosophila melanogaster 44.10 1.00e-79 290.00
IUUC-Ete-032467 Echinops telfairi 44.67 2.00e-78 286.00
IUUC-Eca-034255 Equus caballus 46.44 4.00e-80 292.00
IUUC-Eeu-035273 Erinaceus europaeus 47.15 1.00e-50 194.00
IUUC-Fca-035786 Felis catus 46.33 2.00e-81 296.00
IUUC-Fal-037589 Ficedula albicollis 44.25 9.00e-86 310.00
IUUC-Gmo-039539 Gadus morhua 45.65 2.00e-80 292.00
IUUC-Ggr-039983 Gaeumannomyces graminis 27.91 7.00e-05 42.00
IUUC-Gga-041103 Gallus gallus 43.97 5.00e-85 307.00
IUUC-Gac-041914 Gasterosteus aculeatus 45.96 1.00e-80 293.00
IUUC-Ggo-044712 Gorilla gorilla 45.04 4.00e-69 255.00
IUUC-Hsa-045877 Homo sapiens 44.55 6.00e-83 301.00
IUUC-Kpa-049384 Komagataella pastoris 36.36 8.00e-44 170.00
IUUC-Lch-049793 Latimeria chalumnae 42.55 4.00e-67 248.00
IUUC-Loc-051972 Lepisosteus oculatus 42.99 1.00e-77 283.00
IUUC-Lma-053190 Leptosphaeria maculans 38.95 3.00e-53 203.00
IUUC-Laf-053623 Loxodonta africana 44.24 3.00e-82 299.00
IUUC-Mcc-054943 Macaca mulatta 44.55 8.00e-83 301.00
IUUC-Meu-056259 Macropus eugenii 42.37 4.00e-77 282.00
IUUC-Mla-058890 Melampsora laricipopulina 39.07 5.00e-58 216.00
IUUC-Mga-059671 Meleagris gallopavo 45.34 2.00e-81 296.00
IUUC-Mvi-060481 Microbotryum violaceum 38.38 2.00e-58 219.00
IUUC-Mmr-061003 Microcebus murinus 44.55 9.00e-83 301.00
IUUC-Mdo-062567 Monodelphis domestica 42.99 2.00e-73 270.00
IUUC-Mmu-063584 Mus musculus 44.31 5.00e-84 305.00
IUUC-Mpu-066056 Mustela putorius furo 44.86 2.00e-83 303.00
IUUC-Mlu-067850 Myotis lucifugus 44.86 1.00e-83 303.00
IUUC-Nfi-068537 Neosartorya fischeri 36.39 1.00e-56 214.00
IUUC-Nle-069837 Nomascus leucogenys 46.10 9.00e-80 290.00
IUUC-Opr-070225 Ochotona princeps 43.30 1.00e-73 270.00
IUUC-Ont-071349 Oreochromis niloticus 46.27 7.00e-81 294.00
IUUC-Oan-073668 Ornithorhynchus anatinus 43.92 4.00e-66 243.00
IUUC-Ocu-074706 Oryctolagus cuniculus 44.55 5.00e-83 301.00
IUUC-Ola-086543 Oryzias latipes 44.26 1.00e-80 293.00
IUUC-Oga-088644 Otolemur garnettii 45.08 7.00e-72 264.00
IUUC-Oar-089560 Ovis aries 44.86 1.00e-83 303.00
IUUC-Ptr-090875 Pan troglodytes 44.55 7.00e-83 301.00
IUUC-Pan-091788 Papio anubis 44.55 7.00e-83 301.00
IUUC-Psi-093382 Pelodiscus sinensis 43.83 2.00e-81 296.00
IUUC-Pma-094621 Petromyzon marinus 42.81 1.00e-66 245.00
IUUC-Pno-094984 Phaeosphaeria nodorum 37.11 3.00e-54 206.00
IUUC-Ppa-095609 Physcomitrella patens 38.58 3.00e-48 183.00
IUUC-Pfo-096695 Poecilia formosa 47.65 2.00e-83 303.00
IUUC-Pab-097907 Pongo abelii 44.55 6.00e-83 301.00
IUUC-Pca-100628 Procavia capensis 36.76 8.00e-60 224.00
IUUC-Pva-102416 Pteropus vampyrus 43.30 1.00e-73 270.00
IUUC-Pgr-103554 Puccinia graminis 39.61 8.00e-67 246.00
IUUC-Ptt-103859 Puccinia triticina 38.80 1.00e-60 226.00
IUUC-Pte-104241 Pyrenophora teres 38.58 1.00e-53 204.00
IUUC-Pyt-104741 Pyrenophora triticirepentis 38.58 6.00e-53 201.00
IUUC-Rno-105814 Rattus norvegicus 38.15 5.00e-74 271.00
IUUC-Sce-106445 Saccharomyces cerevisiae 37.12 2.00e-40 158.00
IUUC-Sha-106693 Sarcophilus harrisii 42.68 4.00e-73 268.00
IUUC-Sja-107763 Schizosaccharomyces japonicus 31.44 6.00e-37 147.00
IUUC-Spo-108120 Schizosaccharomyces pombe 32.31 7.00e-42 164.00
IUUC-Smo-109024 Selaginella moellendorffii 35.38 7.00e-49 187.00
IUUC-Stu-112644 Solanum tuberosum 44.44 3.40e+00 25.80
IUUC-Sar-113568 Sorex araneus 43.30 6.00e-73 268.00
IUUC-Sre-115112 Sporisorium reilianum 38.02 1.00e-54 206.00
IUUC-Ssc-115432 Sus scrofa 43.44 4.00e-72 263.00
IUUC-Tgu-117229 Taeniopygia guttata 45.48 4.00e-84 305.00
IUUC-Tru-118423 Takifugu rubripes 46.13 1.00e-82 300.00
IUUC-Tsy-119293 Tarsius syrichta 41.88 8.00e-69 254.00
IUUC-Tni-120753 Tetraodon nigroviridis 45.06 7.00e-77 281.00
IUUC-Tme-127054 Tuber melanosporum 37.04 1.00e-46 181.00
IUUC-Tbe-128138 Tupaia belangeri 43.97 4.00e-66 245.00
IUUC-Ttr-129014 Tursiops truncatus 41.26 5.00e-53 201.00
IUUC-Uma-129458 Ustilago maydis 39.26 8.00e-57 213.00
IUUC-Vpa-130655 Vicugna pacos 39.69 8.00e-64 238.00
IUUC-Xtr-131839 Xenopus tropicalis 45.19 3.00e-80 291.00
IUUC-Xma-133499 Xiphophorus maculatus 47.34 4.00e-83 302.00
IUUC-Yli-134626 Yarrowia lipolytica 37.94 3.00e-46 177.00
Created Date 25-Jun-2017

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