iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025750

UUCD1 version

UUC-CiI-00413

Ensembl Protein ID

ENSCINP00000009377.3

UniProt Accession

F7A8M5; F7A8M5_CIOIN

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000011800.2	ENSCINT00000009377.3	ENSCINP00000009377.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.60e-104	349.0	713	1083

Active Site

Position(s)	Description	Evidence
1051	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
           ++lk  ++v+f +     E+g+d++Gv++efl++++++++npd++lf+ +++++  l+p+p s+l++  hl lF+f+G++lgka+++
   Q: 713  NKLKGIIRVKFINdlgldEAGIDQDGVFKEFLEEIIQKVFNPDMNLFKVTAGGDMKLYPSPLSYLQD-HHLHLFTFVGKMLGKAIYE 798
           57889999*****9***9**********************************************976.******************* PP
   S: 85   grlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVt 166
           g +ld+p++++f++ +l+k        +++l+++dpe+yk+l++ik++ e di+e  ldl+f  +e+i+g+++++eL+pgG+ ipVt
   Q: 799  GIVLDIPFANFFLRSILSKqqtalYSPIDELPALDPEFYKNLTWIKRY-EGDISE--LDLRFMHEEDIMGKIQSHELIPGGAGIPVT 882
           *******************666544667********************.667777..69999999********************** PP
   S: 167  neNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwev 252
           neN+ +Y++ +++yrl+++i  q++af +Gf++vip +++s+F+  el+ li+G+  ++d+ dlkk+  y gg+++++++++w+w++
   Q: 883  NENRIMYIHTLAHYRLHTQILHQTKAFVAGFRSVIPTNWISMFSSPELQRLISGDnVDMDLTDLKKHVVYYGGFHSSHRVVRWLWDI 969
           *******************************************************99****************************** PP
   S: 253  l.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirk...........dasddrlPssnT 303
           l ++ s  +r+afL+FvT++sr Pl Gfa+l+                        +                  +++++rlP+++T
   Q: 970  LeQDYSPSQRSAFLKFVTSCSRPPLLGFANLQpqfsircvevpddedtgdtvatvlR------GflrlpsrsrrsSSHNHRLPTAST 1050
           *889****************************7777777777777776665555441......1555556667756777******** PP
   S: 304  CfnyLkLPeYsskeilkekLlyAieetkgFels 336
           Cfn+LkLP+Y+sk +lk+kL  Ai +++gFels
   Q: 1051 CFNLLKLPNYPSKVVLKDKLKQAIANNTGFELS 1083
           ******************************985 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MFSPSPTKSG QDLVKNAVQA REQRKLSRKR EHSAIILQSS VRGFLTRCEL GKRWRDELDH 60
MIGFDSELEE KNETSHKEMF LVLKKFLFVF NLKKDEQRFV TLCNYLVHNI EASGNIKMCY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTTCAC CAAGTCCAAC AAAAAGTGGG CAGGATTTAG TCAAGAATGC GGTTCAAGCA 60
CGAGAACAAA GAAAGTTATC ACGGAAACGA GAACATTCGG CAATAATTCT ACAATCATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	37.03	3.00e-98	352.00
IUUC-Aml-002107	Ailuropoda melanoleuca	46.70	0.00e+00	978.00
IUUC-Atr-003017	Amborella trichopoda	36.88	3.00e-104	372.00
IUUC-Apl-003328	Anas platyrhynchos	46.34	0.00e+00	926.00
IUUC-Aly-005768	Arabidopsis lyrata	35.30	6.00e-103	367.00
IUUC-Ath-006576	Arabidopsis thaliana	34.54	1.00e-101	363.00
IUUC-Ago-007748	Ashbya gossypii	36.69	7.00e-67	247.00
IUUC-Acl-008158	Aspergillus clavatus	31.05	2.00e-57	216.00
IUUC-Afl-008398	Aspergillus flavus	30.52	1.00e-57	217.00
IUUC-Afu-008937	Aspergillus fumigatus	31.05	1.00e-58	220.00
IUUC-Ani-009252	Aspergillus nidulans	31.05	2.00e-64	239.00
IUUC-Ang-009773	Aspergillus niger	31.33	6.00e-60	224.00
IUUC-Aor-009940	Aspergillus oryzae	30.52	1.00e-57	217.00
IUUC-Ate-010395	Aspergillus terreus	31.46	9.00e-60	224.00
IUUC-Ame-010769	Astyanax mexicanus	36.41	9.00e-62	230.00
IUUC-Bgr-012269	Blumeria graminis	33.06	9.00e-58	216.00
IUUC-Bta-013547	Bos taurus	47.25	0.00e+00	999.00
IUUC-Bci-013743	Botrytis cinerea	34.21	7.00e-68	251.00
IUUC-Bdi-014123	Brachypodium distachyon	35.76	3.00e-101	361.00
IUUC-Bol-015093	Brassica oleracea	38.06	2.00e-102	366.00
IUUC-Bra-016722	Brassica rapa	38.42	4.00e-104	371.00
IUUC-Cel-018447	Caenorhabditis elegans	35.20	1.00e-161	562.00
IUUC-Cja-019855	Callithrix jacchus	46.70	0.00e+00	985.00
IUUC-Cfa-020066	Canis familiaris	46.25	0.00e+00	959.00
IUUC-Cpo-021504	Cavia porcellus	46.94	0.00e+00	994.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	37.08	2.00e-73	270.00
IUUC-Csa-023579	Chlorocebus sabaeus	46.98	0.00e+00	987.00
IUUC-Cho-024430	Choloepus hoffmanni	38.95	0.00e+00	629.00
IUUC-Csv-026016	Ciona savignyi	71.05	0.00e+00	1588.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	31.42	4.00e-67	248.00
IUUC-Cne-026841	Cryptococcus neoformans	37.93	2.00e-71	262.00
IUUC-Cme-027265	Cyanidioschyzon merolae	38.41	2.00e-85	309.00
IUUC-Dre-028271	Danio rerio	45.79	0.00e+00	927.00
IUUC-Dno-029054	Dasypus novemcinctus	47.07	0.00e+00	986.00
IUUC-Dor-030938	Dipodomys ordii	54.62	0.00e+00	716.00
IUUC-Dse-031416	Dothistroma septosporum	30.63	6.00e-63	234.00
IUUC-Dme-031602	Drosophila melanogaster	40.13	0.00e+00	729.00
IUUC-Ete-033041	Echinops telfairi	48.06	1.00e-153	536.00
IUUC-Eca-034411	Equus caballus	46.79	0.00e+00	968.00
IUUC-Eeu-035201	Erinaceus europaeus	53.98	1.00e-150	525.00
IUUC-Fca-036594	Felis catus	46.52	0.00e+00	964.00
IUUC-Fal-037317	Ficedula albicollis	44.95	0.00e+00	926.00
IUUC-Fox-037788	Fusarium oxysporum	32.07	2.00e-70	259.00
IUUC-Fso-038088	Fusarium solani	32.67	1.00e-68	253.00
IUUC-Gmo-039412	Gadus morhua	44.94	0.00e+00	937.00
IUUC-Ggr-039941	Gaeumannomyces graminis	33.47	5.00e-68	251.00
IUUC-Gga-040149	Gallus gallus	46.50	0.00e+00	940.00
IUUC-Gac-042088	Gasterosteus aculeatus	46.21	0.00e+00	979.00
IUUC-Gma-043839	Glycine max	37.04	3.00e-104	371.00
IUUC-Ggo-045279	Gorilla gorilla	46.70	0.00e+00	985.00
IUUC-Hsa-045660	Homo sapiens	46.89	0.00e+00	988.00
IUUC-Hvu-047770	Hordeum vulgare	35.34	4.00e-102	364.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	63.51	6.00e-165	572.00
IUUC-Kpa-049307	Komagataella pastoris	33.26	4.00e-64	238.00
IUUC-Lch-050664	Latimeria chalumnae	46.51	0.00e+00	971.00
IUUC-Lpe-050755	Leersia perrieri	35.00	4.00e-90	325.00
IUUC-Loc-052791	Lepisosteus oculatus	45.99	0.00e+00	936.00
IUUC-Lma-053096	Leptosphaeria maculans	33.81	1.00e-64	241.00
IUUC-Laf-053902	Loxodonta africana	46.70	0.00e+00	984.00
IUUC-Mcc-054730	Macaca mulatta	46.98	0.00e+00	988.00
IUUC-Meu-056527	Macropus eugenii	43.21	0.00e+00	824.00
IUUC-Mor-057021	Magnaporthe oryzae	33.40	6.00e-58	218.00
IUUC-Mpo-057570	Magnaporthe poae	34.85	3.00e-69	255.00
IUUC-Mtr-057671	Medicago truncatula	37.57	8.00e-107	380.00
IUUC-Mla-059124	Melampsora laricipopulina	38.30	2.00e-79	288.00
IUUC-Mga-059260	Meleagris gallopavo	46.46	0.00e+00	943.00
IUUC-Mvi-060445	Microbotryum violaceum	33.17	7.00e-89	321.00
IUUC-Mmr-060804	Microcebus murinus	45.70	0.00e+00	949.00
IUUC-Mdo-062575	Monodelphis domestica	45.76	0.00e+00	920.00
IUUC-Mmu-063636	Mus musculus	45.65	0.00e+00	938.00
IUUC-Mac-065275	Musa acuminata	32.92	3.00e-100	358.00
IUUC-Mpu-066677	Mustela putorius furo	46.48	0.00e+00	914.00
IUUC-Mlu-067952	Myotis lucifugus	46.98	0.00e+00	954.00
IUUC-Nfi-068280	Neosartorya fischeri	31.05	9.00e-59	221.00
IUUC-Ncr-068869	Neurospora crassa	33.27	8.00e-63	234.00
IUUC-Nle-069153	Nomascus leucogenys	46.89	0.00e+00	986.00
IUUC-Opr-070554	Ochotona princeps	48.00	0.00e+00	928.00
IUUC-Ont-071372	Oreochromis niloticus	45.97	0.00e+00	954.00
IUUC-Ocu-074183	Oryctolagus cuniculus	46.70	0.00e+00	974.00
IUUC-Oba-075006	Oryza barthii	35.50	5.00e-104	371.00
IUUC-Obr-076133	Oryza brachyantha	34.78	3.00e-103	369.00
IUUC-Ogl-077003	Oryza glaberrima	35.50	5.00e-104	370.00
IUUC-Ogu-078947	Oryza glumaepatula	35.70	1.00e-102	366.00
IUUC-Oin-080058	Oryza indica	37.32	8.00e-102	363.00
IUUC-Olo-080475	Oryza longistaminata	35.60	8.00e-104	370.00
IUUC-Ome-081741	Oryza meridionalis	36.87	9.00e-97	347.00
IUUC-Oni-082385	Oryza nivara	35.70	8.00e-103	367.00
IUUC-Opu-083529	Oryza punctata	37.32	3.00e-102	365.00
IUUC-Oru-085128	Oryza rufipogon	36.21	2.00e-91	328.00
IUUC-Osa-085355	Oryza sativa	35.60	2.00e-103	369.00
IUUC-Ola-087337	Oryzias latipes	45.78	0.00e+00	924.00
IUUC-Olu-087699	Ostreococcus lucimarinus	40.00	2.00e-76	277.00
IUUC-Oga-088342	Otolemur garnettii	47.09	0.00e+00	937.00
IUUC-Oar-090234	Ovis aries	47.22	0.00e+00	984.00
IUUC-Ptr-091661	Pan troglodytes	46.70	0.00e+00	986.00
IUUC-Pan-092728	Papio anubis	47.12	0.00e+00	985.00
IUUC-Psi-093251	Pelodiscus sinensis	45.46	0.00e+00	865.00
IUUC-Pma-094195	Petromyzon marinus	44.23	0.00e+00	864.00
IUUC-Ppa-095682	Physcomitrella patens	36.66	3.00e-110	391.00
IUUC-Pfo-097472	Poecilia formosa	45.89	0.00e+00	955.00
IUUC-Pab-098570	Pongo abelii	46.89	0.00e+00	989.00
IUUC-Pop-098928	Populus trichocarpa	35.80	2.00e-95	342.00
IUUC-Pca-100110	Procavia capensis	41.48	0.00e+00	807.00
IUUC-Ppe-101281	Prunus persica	37.86	1.00e-103	370.00
IUUC-Pva-102887	Pteropus vampyrus	45.01	0.00e+00	909.00
IUUC-Pgr-103513	Puccinia graminis	33.80	2.00e-78	286.00
IUUC-Ptt-103967	Puccinia triticina	31.81	2.00e-68	253.00
IUUC-Pte-104105	Pyrenophora teres	32.79	3.00e-64	239.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	32.79	3.00e-64	239.00
IUUC-Rno-106028	Rattus norvegicus	44.00	0.00e+00	849.00
IUUC-Sce-106446	Saccharomyces cerevisiae	33.04	5.00e-54	204.00
IUUC-Sha-107331	Sarcophilus harrisii	46.94	0.00e+00	937.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	34.03	2.00e-82	299.00
IUUC-Spo-108097	Schizosaccharomyces pombe	33.51	1.00e-78	286.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	33.00	3.00e-64	239.00
IUUC-Smo-109537	Selaginella moellendorffii	37.68	6.00e-105	374.00
IUUC-Sit-110457	Setaria italica	35.80	9.00e-98	350.00
IUUC-Sly-111362	Solanum lycopersicum	35.80	5.00e-98	351.00
IUUC-Sar-113287	Sorex araneus	53.87	1.00e-101	362.00
IUUC-Sbi-113882	Sorghum bicolor	35.38	1.00e-95	343.00
IUUC-Sre-115038	Sporisorium reilianum	39.63	1.00e-81	296.00
IUUC-Ssc-116103	Sus scrofa	46.89	0.00e+00	968.00
IUUC-Tgu-117275	Taeniopygia guttata	46.50	0.00e+00	941.00
IUUC-Tru-118681	Takifugu rubripes	45.40	0.00e+00	968.00
IUUC-Tsy-118985	Tarsius syrichta	34.78	1.00e-90	327.00
IUUC-Tni-120850	Tetraodon nigroviridis	64.56	1.00e-159	554.00
IUUC-Tca-121770	Theobroma cacao	38.57	1.00e-106	380.00
IUUC-Tre-121892	Trichoderma reesei	33.94	6.00e-74	271.00
IUUC-Tvi-122354	Trichoderma virens	34.14	1.00e-73	270.00
IUUC-Tae-125229	Triticum aestivum	35.34	3.00e-102	365.00
IUUC-Tur-126086	Triticum urartu	37.03	3.00e-98	352.00
IUUC-Tme-127102	Tuber melanosporum	32.93	5.00e-66	244.00
IUUC-Tbe-127461	Tupaia belangeri	43.46	0.00e+00	847.00
IUUC-Ttr-129269	Tursiops truncatus	46.06	0.00e+00	943.00
IUUC-Uma-129343	Ustilago maydis	38.94	4.00e-83	301.00
IUUC-Vda-129748	Verticillium dahliae	31.47	4.00e-58	218.00
IUUC-Vpa-130523	Vicugna pacos	70.55	5.00e-64	238.00
IUUC-Vvi-131524	Vitis vinifera	37.88	1.00e-105	376.00
IUUC-Xtr-132146	Xenopus tropicalis	46.12	0.00e+00	957.00
IUUC-Xma-133526	Xiphophorus maculatus	46.06	0.00e+00	954.00
IUUC-Yli-134496	Yarrowia lipolytica	34.30	3.00e-72	265.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence