iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-087209

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04030959

Gene Name

ube3c

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000010581.1	ENSORLT00000013265.1	ENSORLP00000013264.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.60e-106	355.0	746	1083

Active Site

Position(s)	Description	Evidence
1051	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
            dlkkr++v++++     E+g+d gG++refl++l+k  +np+ g+f++++++    +p+ ++ +  +  +++++flGr+lgkal++
   Q: 746  PDLKKRIRVHLLNahgldEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAEMLVG-ESFTRHYYFLGRILGKALYE 831
           689**********99**9**********************************99999999999985.59****************** PP
   S: 85   grlldlplsksfyklllgk..klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneN 169
           + l++lp++++f+++llg+  ++++++l+++dpe+y++l ++k++ e+d+eelgl++t+   ++ lge++++eLkpgG++ipVt +N
   Q: 832  NMLVELPFASFFLSKLLGTsaDVDIHHLASLDPEMYRNLLFLKSY-EDDVEELGLNFTV--VNNDLGEAQVVELKPGGKDIPVTTAN 915
           ******************9666889********************.6788887666665..5889********************** PP
   S: 170  keeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevlee 255
           + +Y++lv++yrl++ ++ ++ afr+G+ +v++le+l++F+++e+++li+G    i++edlk++t+y ggy++++p+iq Fwev+e+
   Q: 916  RIAYIHLVADYRLNKHMRPHCLAFRQGLANVVNLEWLRMFDQQEIQVLISGAyVPISLEDLKNFTNYSGGYSANHPVIQIFWEVVEG 1002
           ****************************************************9********************************** PP
   S: 256  fsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++ee++++L+FvT++sr Pl Gf+el+p  f+i++ +sd +rlP+++TC+n+LkLPe+  ++ +++kLlyAie+++gFels
   Q: 1003 FTEEEKRKLLRFVTSCSRPPLLGFKELHPA-FCIHNGGSDlERLPTASTCMNLLKLPEFCDQQSMRSKLLYAIESSAGFELS 1083
           ****************************88.*****99999**************************************985 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MFSFEGDFKT RPKVSLGGAS KKEEKASLLH RTQEERRKRE DERKRLKNAI IIQSYIRGYQ 60
DMKQQYAIQR AQFDTFVSQT QAGGAQHVLD SSDLCLLSRR LIFFYRQNLD SHRLIWLCQN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTAGCT TCGAGGGAGA TTTCAAAACA AGACCCAAGG TGTCCCTTGG AGGAGCAAGT 60
AAAAAGGTAC ATGTTATGTG TATAGAAGTA TAATTGTGAG TCTTTTTTTA GCTATAGTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	76.14	0.00e+00	1607.00
IUUC-Apl-003731	Anas platyrhynchos	79.26	0.00e+00	1706.00
IUUC-Aca-005248	Anolis carolinensis	79.43	0.00e+00	1726.00
IUUC-Aly-005768	Arabidopsis lyrata	34.05	9.00e-107	381.00
IUUC-Ath-006576	Arabidopsis thaliana	30.16	9.00e-114	404.00
IUUC-Ago-007748	Ashbya gossypii	41.43	2.00e-78	287.00
IUUC-Acl-008158	Aspergillus clavatus	38.89	4.00e-77	283.00
IUUC-Afl-008398	Aspergillus flavus	39.23	4.00e-79	290.00
IUUC-Afu-008937	Aspergillus fumigatus	39.15	3.00e-79	290.00
IUUC-Ani-009252	Aspergillus nidulans	38.46	2.00e-80	293.00
IUUC-Ang-009773	Aspergillus niger	38.46	1.00e-76	281.00
IUUC-Aor-009940	Aspergillus oryzae	39.23	4.00e-79	290.00
IUUC-Ate-010395	Aspergillus terreus	39.10	1.00e-79	291.00
IUUC-Ame-010769	Astyanax mexicanus	67.22	0.00e+00	1112.00
IUUC-Bgr-012269	Blumeria graminis	36.90	2.00e-74	272.00
IUUC-Bta-012841	Bos taurus	76.68	0.00e+00	1642.00
IUUC-Bci-013743	Botrytis cinerea	38.25	2.00e-82	301.00
IUUC-Bdi-014123	Brachypodium distachyon	45.78	2.00e-103	370.00
IUUC-Bol-015390	Brassica oleracea	30.34	6.00e-109	388.00
IUUC-Bra-016853	Brassica rapa	31.07	2.00e-115	410.00
IUUC-Cel-018638	Caenorhabditis elegans	32.34	5.00e-90	325.00
IUUC-Cja-019743	Callithrix jacchus	76.02	0.00e+00	1618.00
IUUC-Cfa-021031	Canis familiaris	77.30	0.00e+00	1664.00
IUUC-Cpo-022401	Cavia porcellus	77.93	0.00e+00	1668.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	44.76	1.00e-86	313.00
IUUC-Csa-024107	Chlorocebus sabaeus	77.93	0.00e+00	1682.00
IUUC-Cho-024750	Choloepus hoffmanni	75.21	0.00e+00	730.00
IUUC-Cin-025432	Ciona intestinalis	46.34	1.00e-98	353.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	33.10	3.00e-85	310.00
IUUC-Cne-026841	Cryptococcus neoformans	36.24	4.00e-97	349.00
IUUC-Cme-027265	Cyanidioschyzon merolae	47.10	5.00e-106	379.00
IUUC-Dre-028196	Danio rerio	83.56	0.00e+00	1727.00
IUUC-Dno-029024	Dasypus novemcinctus	77.74	0.00e+00	1683.00
IUUC-Dor-030483	Dipodomys ordii	81.20	3.00e-175	609.00
IUUC-Dse-031416	Dothistroma septosporum	34.02	1.00e-78	288.00
IUUC-Dme-031946	Drosophila melanogaster	36.32	0.00e+00	683.00
IUUC-Ete-032240	Echinops telfairi	70.36	2.00e-149	523.00
IUUC-Eca-033828	Equus caballus	76.93	0.00e+00	1628.00
IUUC-Eeu-034604	Erinaceus europaeus	81.54	2.00e-121	430.00
IUUC-Fca-035907	Felis catus	77.49	0.00e+00	1671.00
IUUC-Fal-037389	Ficedula albicollis	78.97	0.00e+00	1716.00
IUUC-Fox-037788	Fusarium oxysporum	36.64	9.00e-90	325.00
IUUC-Fso-038088	Fusarium solani	35.04	1.00e-83	304.00
IUUC-Gmo-039254	Gadus morhua	75.25	0.00e+00	1403.00
IUUC-Ggr-039941	Gaeumannomyces graminis	33.62	1.00e-82	301.00
IUUC-Gga-040310	Gallus gallus	79.24	0.00e+00	1711.00
IUUC-Gac-042054	Gasterosteus aculeatus	82.40	0.00e+00	1521.00
IUUC-Gma-042836	Glycine max	30.04	3.00e-104	373.00
IUUC-Ggo-045031	Gorilla gorilla	78.21	0.00e+00	1687.00
IUUC-Hsa-045880	Homo sapiens	78.12	0.00e+00	1686.00
IUUC-Itr-048555	Ictidomys tridecemlineatus	61.61	2.00e-143	501.00
IUUC-Kpa-049307	Komagataella pastoris	33.98	9.00e-69	255.00
IUUC-Lch-050403	Latimeria chalumnae	77.97	0.00e+00	1605.00
IUUC-Loc-052218	Lepisosteus oculatus	84.79	0.00e+00	1790.00
IUUC-Lma-053096	Leptosphaeria maculans	38.44	1.00e-80	295.00
IUUC-Laf-054162	Loxodonta africana	74.23	0.00e+00	1409.00
IUUC-Mcc-055127	Macaca mulatta	77.84	0.00e+00	1680.00
IUUC-Meu-056187	Macropus eugenii	80.00	3.00e-102	366.00
IUUC-Mor-057021	Magnaporthe oryzae	33.39	9.00e-77	282.00
IUUC-Mpo-057570	Magnaporthe poae	36.90	1.00e-76	281.00
IUUC-Mtr-058154	Medicago truncatula	34.23	6.00e-105	375.00
IUUC-Mla-059124	Melampsora laricipopulina	47.65	2.00e-101	362.00
IUUC-Mga-059581	Meleagris gallopavo	78.85	0.00e+00	1691.00
IUUC-Mvi-060445	Microbotryum violaceum	38.45	2.00e-102	367.00
IUUC-Mmr-061360	Microcebus murinus	74.74	0.00e+00	1545.00
IUUC-Mdo-062194	Monodelphis domestica	75.98	0.00e+00	1695.00
IUUC-Mmu-064189	Mus musculus	77.84	0.00e+00	1678.00
IUUC-Mac-065275	Musa acuminata	48.56	7.00e-109	388.00
IUUC-Mpu-066439	Mustela putorius furo	75.84	0.00e+00	1593.00
IUUC-Mlu-068228	Myotis lucifugus	75.53	0.00e+00	1614.00
IUUC-Nfi-068280	Neosartorya fischeri	39.36	1.00e-79	291.00
IUUC-Ncr-068869	Neurospora crassa	36.14	6.00e-85	309.00
IUUC-Nle-069687	Nomascus leucogenys	77.38	0.00e+00	1628.00
IUUC-Opr-070592	Ochotona princeps	91.00	3.00e-108	386.00
IUUC-Ont-071836	Oreochromis niloticus	91.04	0.00e+00	1914.00
IUUC-Oan-072800	Ornithorhynchus anatinus	79.43	0.00e+00	1734.00
IUUC-Ocu-074587	Oryctolagus cuniculus	78.30	0.00e+00	1692.00
IUUC-Olu-087699	Ostreococcus lucimarinus	42.86	1.00e-87	316.00
IUUC-Oga-088776	Otolemur garnettii	75.16	0.00e+00	1554.00
IUUC-Oar-089441	Ovis aries	76.52	0.00e+00	1628.00
IUUC-Ptr-091273	Pan troglodytes	78.12	0.00e+00	1687.00
IUUC-Pan-091981	Papio anubis	78.02	0.00e+00	1684.00
IUUC-Psi-093203	Pelodiscus sinensis	78.13	0.00e+00	1479.00
IUUC-Pma-094738	Petromyzon marinus	64.78	0.00e+00	1335.00
IUUC-Pno-095132	Phaeosphaeria nodorum	29.47	2.00e-60	227.00
IUUC-Pfo-097511	Poecilia formosa	91.60	0.00e+00	1937.00
IUUC-Pab-098634	Pongo abelii	75.28	0.00e+00	1607.00
IUUC-Pop-098928	Populus trichocarpa	29.53	4.00e-106	379.00
IUUC-Pca-100987	Procavia capensis	91.64	0.00e+00	743.00
IUUC-Pva-103034	Pteropus vampyrus	72.58	0.00e+00	1524.00
IUUC-Pgr-103513	Puccinia graminis	42.22	3.00e-106	379.00
IUUC-Ptt-103967	Puccinia triticina	41.20	6.00e-95	342.00
IUUC-Pte-104105	Pyrenophora teres	35.48	4.00e-81	296.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	38.66	3.00e-78	287.00
IUUC-Rno-105380	Rattus norvegicus	76.61	0.00e+00	1453.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.62	1.00e-69	257.00
IUUC-Sha-107108	Sarcophilus harrisii	72.93	0.00e+00	1554.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	43.66	2.00e-97	350.00
IUUC-Spo-108097	Schizosaccharomyces pombe	45.34	1.00e-97	350.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	30.45	1.00e-82	301.00
IUUC-Sly-111362	Solanum lycopersicum	33.60	2.00e-99	357.00
IUUC-Sar-113687	Sorex araneus	73.88	0.00e+00	823.00
IUUC-Sre-115038	Sporisorium reilianum	44.33	4.00e-99	356.00
IUUC-Ssc-115378	Sus scrofa	88.59	0.00e+00	702.00
IUUC-Tgu-116729	Taeniopygia guttata	78.43	0.00e+00	1702.00
IUUC-Tru-118068	Takifugu rubripes	87.63	0.00e+00	1823.00
IUUC-Tsy-118942	Tarsius syrichta	77.48	2.00e-174	606.00
IUUC-Tni-120732	Tetraodon nigroviridis	87.30	0.00e+00	1778.00
IUUC-Tre-121892	Trichoderma reesei	35.69	9.00e-87	315.00
IUUC-Tvi-122354	Trichoderma virens	34.81	5.00e-87	316.00
IUUC-Tme-127102	Tuber melanosporum	35.69	5.00e-92	332.00
IUUC-Tbe-127351	Tupaia belangeri	68.65	0.00e+00	1307.00
IUUC-Ttr-129061	Tursiops truncatus	74.45	0.00e+00	1580.00
IUUC-Uma-129343	Ustilago maydis	44.09	1.00e-99	358.00
IUUC-Vda-129748	Verticillium dahliae	37.42	1.00e-78	288.00
IUUC-Vvi-131234	Vitis vinifera	30.48	9.00e-109	388.00
IUUC-Xtr-132094	Xenopus tropicalis	78.36	0.00e+00	1649.00
IUUC-Xma-133923	Xiphophorus maculatus	91.78	0.00e+00	1941.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence