iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-001733

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01115918

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000016515.1	ENSAMET00000018158.1	ENSAMEP00000017446.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.50e-69	234.1	69	504

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p + + l e +++ ++++++  +++ l+ +l +l+++l     +++++ + + ll++l+++  ++s++
   Q: 69   GLVNLGNTCFMNSLLQGLSACPAFIKWLEEFTTQYTRDQKEAPSHQYLSLTLLHLLKALScqeVTDDEVLDASCLLDVLRMYRWQISSF 157
           9*****************************77777777777888999************888899999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E+++++ ++le+e    ++ +++++++ ++ e++ e          + + ++++n+   ++ F+g+l+s+++c++c+++s +r
   Q: 158  EEQDAHELFHVITSSLEDER--DRQPRVTHLFDVHSLEQQPEitpkqitcrtRGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQSpVR 244
           *******************9..678889999999988888888999999999999********************************** PP
   S: 166  eepfldlslpvpgke...etkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkR 236
           +++f +lsl++p  +   + ++++l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R
   Q: 245  FDTFDSLSLSIPAATwvlKGHPLTLDHCLHHFISSESVRD---VVCDNCTqieakgtsngekvehQRTTFVKQLKLGKLPQCLCIHLQR 330
           ************88722234566***************97...9******8888888888888777777******************** PP
   S: 237  fsfseeqksrekinkkvefpleLdlspfcts....................................peekqke............... 274
            s+s++ + + k +++v+f++ L ++ +  +                                    p                     
   Q: 331  LSWSSH-GAPLKRHEHVQFNEFLMMDIYKYHllghkpgqhspkpgeaggppddlqdgpaapssvlnqP-----Ggpktqifmngacsps 413
           ***998.8888*********888887555555567777766666666666666666666655555550.....0555555555555555 PP
   S: 275  ......................kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYv 332
                                 ++ ++L+avvvH+G ++sGH+v+y ++         ++++Wl ++D++V++ + +evl+   s+aY+
   Q: 414  llpplpaplpfplpvvpdysssTYLFRLMAVVVHHGDMHSGHFVTYRRSppsaknplsTSNQWLWISDDTVRKASLQEVLS---SSAYL 499
           55555555555555555555559999***********************9999888888999*******************...***** PP
   S: 333  lfYkr 337
           lfY+r
   Q: 500  LFYER 504
           ***98 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MLSSRAQAAM TAADRAIQRF LRTGAAVRYK VMKNWGVIGG IAAALAAGIY VIWGPITERK 60
KRRKGLVPGL VNLGNTCFMN SLLQGLSACP AFIKWLEEFT TQYTRDQKEA PSHQYLSLTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGAGCT CCCGGGCTCA GGCGGCGATG ACCGCGGCGG ACCGGGCCAT CCAGCGCTTC 60
CTGCGGACCG GGGCGGCCGT CAGGTGAGCC TTGGGGGGCG GGGCGGCCCG AGAGGCCGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	27.53	6.00e-14	72.00
IUUC-Atr-002510	Amborella trichopoda	24.14	4.00e-20	93.20
IUUC-Apl-003645	Anas platyrhynchos	71.43	5.00e-101	360.00
IUUC-Aca-004583	Anolis carolinensis	69.86	6.00e-24	101.00
IUUC-Aly-005754	Arabidopsis lyrata	24.74	2.00e-22	100.00
IUUC-Ath-007622	Arabidopsis thaliana	26.82	3.00e-21	96.30
IUUC-Acl-008136	Aspergillus clavatus	21.51	1.00e-10	62.00
IUUC-Ame-010896	Astyanax mexicanus	60.46	4.00e-149	521.00
IUUC-Bta-012321	Bos taurus	92.12	0.00e+00	859.00
IUUC-Bci-013590	Botrytis cinerea	22.22	5.00e-13	69.70
IUUC-Bdi-014795	Brachypodium distachyon	26.75	4.00e-14	72.80
IUUC-Bol-015637	Brassica oleracea	27.25	8.00e-23	101.00
IUUC-Bra-016801	Brassica rapa	26.81	8.00e-23	101.00
IUUC-Cel-018308	Caenorhabditis elegans	27.95	4.00e-34	139.00
IUUC-Cja-018826	Callithrix jacchus	93.09	0.00e+00	882.00
IUUC-Cfa-021206	Canis familiaris	95.00	0.00e+00	921.00
IUUC-Cpo-021343	Cavia porcellus	90.48	0.00e+00	838.00
IUUC-Csa-023419	Chlorocebus sabaeus	93.08	0.00e+00	880.00
IUUC-Cho-024475	Choloepus hoffmanni	88.13	5.00e-136	477.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	20.60	1.00e-11	65.10
IUUC-Cne-027061	Cryptococcus neoformans	25.19	1.00e-10	62.00
IUUC-Dre-027563	Danio rerio	57.72	1.00e-153	536.00
IUUC-Dno-029929	Dasypus novemcinctus	91.35	0.00e+00	887.00
IUUC-Dor-030166	Dipodomys ordii	82.50	0.00e+00	742.00
IUUC-Dme-031627	Drosophila melanogaster	36.73	2.00e-21	97.40
IUUC-Ete-032634	Echinops telfairi	79.62	0.00e+00	687.00
IUUC-Eca-033968	Equus caballus	92.09	0.00e+00	832.00
IUUC-Eeu-035279	Erinaceus europaeus	82.32	3.00e-59	222.00
IUUC-Fca-036525	Felis catus	96.54	0.00e+00	924.00
IUUC-Fal-036606	Ficedula albicollis	76.99	8.00e-158	549.00
IUUC-Gmo-038726	Gadus morhua	54.71	1.00e-141	496.00
IUUC-Gga-040718	Gallus gallus	76.58	2.00e-158	551.00
IUUC-Gac-042645	Gasterosteus aculeatus	55.86	2.00e-145	509.00
IUUC-Gma-042890	Glycine max	25.66	1.00e-16	81.60
IUUC-Ggo-045021	Gorilla gorilla	93.08	0.00e+00	878.00
IUUC-Hsa-045832	Homo sapiens	93.08	0.00e+00	878.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	93.10	0.00e+00	847.00
IUUC-Lch-050662	Latimeria chalumnae	69.89	5.00e-177	613.00
IUUC-Lpe-051078	Leersia perrieri	25.40	3.00e-28	119.00
IUUC-Loc-052611	Lepisosteus oculatus	64.74	3.00e-174	604.00
IUUC-Lma-053048	Leptosphaeria maculans	20.43	8.00e-13	69.30
IUUC-Laf-053752	Loxodonta africana	91.28	0.00e+00	832.00
IUUC-Mcc-054892	Macaca mulatta	93.46	0.00e+00	884.00
IUUC-Meu-056673	Macropus eugenii	72.54	2.00e-154	538.00
IUUC-Mtr-057976	Medicago truncatula	26.26	1.00e-30	127.00
IUUC-Mla-058970	Melampsora laricipopulina	21.19	2.00e-11	63.90
IUUC-Mga-059543	Meleagris gallopavo	75.44	0.00e+00	645.00
IUUC-Mmr-061534	Microcebus murinus	92.31	0.00e+00	879.00
IUUC-Mdo-062140	Monodelphis domestica	68.23	2.00e-167	582.00
IUUC-Mmu-063673	Mus musculus	89.04	0.00e+00	835.00
IUUC-Mpu-066328	Mustela putorius furo	95.58	0.00e+00	886.00
IUUC-Mlu-067938	Myotis lucifugus	94.04	0.00e+00	919.00
IUUC-Nle-069426	Nomascus leucogenys	91.69	0.00e+00	778.00
IUUC-Opr-070796	Ochotona princeps	83.66	4.00e-116	411.00
IUUC-Ont-072248	Oreochromis niloticus	56.87	6.00e-153	533.00
IUUC-Oan-072916	Ornithorhynchus anatinus	79.07	0.00e+00	740.00
IUUC-Ocu-074459	Oryctolagus cuniculus	85.24	0.00e+00	646.00
IUUC-Oba-075765	Oryza barthii	25.61	2.00e-20	93.60
IUUC-Obr-076005	Oryza brachyantha	26.19	3.00e-27	116.00
IUUC-Ogl-077916	Oryza glaberrima	26.85	5.00e-23	102.00
IUUC-Ogu-078263	Oryza glumaepatula	25.88	9.00e-21	95.10
IUUC-Oin-080096	Oryza indica	27.47	2.00e-14	73.60
IUUC-Ome-081928	Oryza meridionalis	26.72	1.00e-28	120.00
IUUC-Oni-082424	Oryza nivara	25.88	9.00e-21	95.10
IUUC-Oru-085117	Oryza rufipogon	25.88	9.00e-21	95.10
IUUC-Ola-087429	Oryzias latipes	55.49	5.00e-145	507.00
IUUC-Oga-087981	Otolemur garnettii	92.69	0.00e+00	876.00
IUUC-Oar-089927	Ovis aries	91.35	0.00e+00	852.00
IUUC-Ptr-090878	Pan troglodytes	93.08	0.00e+00	878.00
IUUC-Pan-092698	Papio anubis	93.46	0.00e+00	884.00
IUUC-Psi-093451	Pelodiscus sinensis	75.86	0.00e+00	689.00
IUUC-Pfo-096096	Poecilia formosa	57.52	3.00e-153	535.00
IUUC-Pab-098676	Pongo abelii	91.92	0.00e+00	858.00
IUUC-Pca-100418	Procavia capensis	94.70	2.00e-128	452.00
IUUC-Ppe-101898	Prunus persica	24.86	1.00e-18	87.80
IUUC-Pva-103018	Pteropus vampyrus	91.15	0.00e+00	877.00
IUUC-Pgr-103423	Puccinia graminis	26.29	1.00e-09	58.90
IUUC-Pte-104330	Pyrenophora teres	22.42	4.00e-15	76.60
IUUC-Pyt-104518	Pyrenophora triticirepentis	21.83	3.00e-17	84.00
IUUC-Rno-105708	Rattus norvegicus	88.27	0.00e+00	824.00
IUUC-Sha-106971	Sarcophilus harrisii	77.52	0.00e+00	741.00
IUUC-Ssl-108648	Sclerotinia sclerotiorum	22.31	1.00e-11	65.10
IUUC-Sit-110442	Setaria italica	25.94	8.00e-26	111.00
IUUC-Ssc-116397	Sus scrofa	91.73	0.00e+00	867.00
IUUC-Tgu-117446	Taeniopygia guttata	69.26	0.00e+00	630.00
IUUC-Tru-118268	Takifugu rubripes	56.06	9.00e-138	483.00
IUUC-Tsy-119484	Tarsius syrichta	92.91	1.00e-54	207.00
IUUC-Tni-119735	Tetraodon nigroviridis	54.10	8.00e-119	420.00
IUUC-Tca-121660	Theobroma cacao	24.86	8.00e-27	115.00
IUUC-Tae-125383	Triticum aestivum	26.96	2.00e-25	110.00
IUUC-Tur-126458	Triticum urartu	27.36	1.00e-15	77.80
IUUC-Tbe-127740	Tupaia belangeri	86.15	0.00e+00	790.00
IUUC-Ttr-129273	Tursiops truncatus	89.04	0.00e+00	829.00
IUUC-Vvi-131177	Vitis vinifera	27.27	8.00e-20	91.70
IUUC-Xtr-132374	Xenopus tropicalis	64.82	2.00e-166	578.00
IUUC-Xma-133267	Xiphophorus maculatus	59.33	4.00e-154	538.00
IUUC-Zma-135796	Zea mays	25.87	5.00e-25	108.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence