iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049307

Ensembl Protein ID

CAY68770

UniProt Accession

C4QZU6; C4QZU6_KOMPG

Genbank Protein ID

CAY68770.1

Protein Name

Ubiquitin-conjugating enzyme (E4), elongates polyubiquitin chains on substrate proteins

Genbank Nucleotide ID

FN392320

Gene Name

PAS_chr2-1_0164

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr2-1_0164	CAY68770	CAY68770

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.50e-80	268.0	635	989

Active Site

Position(s)	Description	Evidence
957	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg....EegldlgGvtreflallskelqnpd.......lglflysendketlqpnpdsglknp......ehlklFeflGrllgkalqdgr 86
           ++lk+ l ++f++    E+g+d gG+t+efl++ +k+ + ++       l lf++s   +++++pnp+ +lk +      + l++ ++lG ++gk+l+++ 
   Q: 635  EQLKNYLGIQFTNqfgaEAGIDGGGLTKEFLTETVKKGFATTnesgvedLMLFKHS--PRNEIYPNPALYLKRTkgvdvhKDLEMIRYLGSIVGKCLYEKI 733
           56888888999999999*******************99998878888555556555..5666778888888776888888********************* PP
   S: 87   lldlplsksfyklllgk...klsledleevdpelykslkeikenaesdieelgldltfsvseei....lgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           l+dlp+s++f+ +   +   k  ++dl+  d++l+++l+++++++++++++l  +l+f+ +e+       +t++ +L+p+G+nipVt +N+ +Yv +v ++
   Q: 734  LVDLPFSPFFLTRWSVNqpyKTMFDDLKYYDEDLFRNLNKLLSLNSDQVDAL--ELNFTLTERFyyngAFKTTTIMLLPNGANIPVTTANRLQYVFAVSNF 832
           ***********9987665555666******************9966566665..5555555555445555677777************************* PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevl.eefsseerkafLqFvTgssrlPlgGf 279
           +l ++ + q++ f +G+ +vip ++l++F++ el++l++G+ + id++dl+k+t + + yte++++i+ ++++l ++fs+eer++f++FvT+ss++Pl Gf
   Q: 833  KLYTSLRLQTDYFLQGLFKVIPSQWLEVFNPMELQILVSGRdRGIDISDLRKNTVFSE-YTENDQTIIDLFDILeHDFSNEERSKFIRFVTSSSKAPLLGF 932
           *****************************************999************77.***************99************************* PP
   S: 280  aelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
            +l+p+ f +r+     drlPs+ TCfn+LkLP+Y + ++lkekLlyAi++++gF+ls
   Q: 933  SQLNPK-FGVRNiGPFSDRLPSAFTCFNQLKLPDYGNRKVLKEKLLYAISSESGFDLS 989
           ****98.8888857777**************************************985 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MFNFDGSTKR RNVNLSGRRN NLESREQLLH RAELERNRRK EAKLQDKSVR IIQSYIRTFL 60
LRSHISLEFE KIWLHCGSDV TALNMFAFFC PNLVLKRDEA WLQVQLDHVS KLLLSSHGSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTAACT TCGACGGATC AACCAAGAGG CGGAATGTAA ACCTTAGTGG GAGAAGGAAT 60
AATCTTGAAA GCAGAGAGCA ACTGCTTCAT AGAGCCGAAT TGGAGAGGAA TAGACGGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ppa:PAS_chr2-1_0164

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	36.38	9.00e-60	223.00
IUUC-Aml-002107	Ailuropoda melanoleuca	32.29	7.00e-65	240.00
IUUC-Atr-003017	Amborella trichopoda	37.41	2.00e-66	245.00
IUUC-Apl-003731	Anas platyrhynchos	36.75	4.00e-67	248.00
IUUC-Aca-005248	Anolis carolinensis	36.75	1.00e-66	246.00
IUUC-Aly-005768	Arabidopsis lyrata	36.58	2.00e-70	259.00
IUUC-Ath-006576	Arabidopsis thaliana	36.58	1.00e-70	259.00
IUUC-Ago-007748	Ashbya gossypii	36.77	5.00e-87	313.00
IUUC-Acl-008158	Aspergillus clavatus	33.50	4.00e-73	268.00
IUUC-Afl-008398	Aspergillus flavus	38.10	6.00e-76	277.00
IUUC-Afu-008937	Aspergillus fumigatus	34.43	3.00e-78	285.00
IUUC-Ani-009252	Aspergillus nidulans	32.69	2.00e-78	285.00
IUUC-Ang-009773	Aspergillus niger	34.04	6.00e-76	277.00
IUUC-Aor-009940	Aspergillus oryzae	38.10	5.00e-76	277.00
IUUC-Ate-010395	Aspergillus terreus	36.93	4.00e-74	271.00
IUUC-Ame-010769	Astyanax mexicanus	33.86	5.00e-50	191.00
IUUC-Bgr-012269	Blumeria graminis	39.86	2.00e-70	257.00
IUUC-Bta-012841	Bos taurus	36.52	6.00e-66	243.00
IUUC-Bci-013743	Botrytis cinerea	36.95	1.00e-75	276.00
IUUC-Bdi-014123	Brachypodium distachyon	36.14	3.00e-72	264.00
IUUC-Bol-015390	Brassica oleracea	36.56	1.00e-64	239.00
IUUC-Bra-016853	Brassica rapa	37.03	3.00e-69	254.00
IUUC-Cel-018447	Caenorhabditis elegans	36.07	5.00e-57	214.00
IUUC-Cja-019855	Callithrix jacchus	32.29	4.00e-65	241.00
IUUC-Cfa-021031	Canis familiaris	36.28	1.00e-64	239.00
IUUC-Cpo-022401	Cavia porcellus	36.52	3.00e-65	241.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	33.83	7.00e-57	212.00
IUUC-Csa-024107	Chlorocebus sabaeus	36.75	9.00e-66	243.00
IUUC-Cho-024750	Choloepus hoffmanni	37.01	3.00e-57	214.00
IUUC-Cin-025750	Ciona intestinalis	33.04	6.00e-62	230.00
IUUC-Csv-026016	Ciona savignyi	35.12	4.00e-62	231.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	36.77	1.00e-78	286.00
IUUC-Cne-026841	Cryptococcus neoformans	31.21	2.00e-73	268.00
IUUC-Cme-027265	Cyanidioschyzon merolae	38.73	2.00e-77	281.00
IUUC-Dre-028196	Danio rerio	33.46	8.00e-68	250.00
IUUC-Dno-029054	Dasypus novemcinctus	32.29	2.00e-65	242.00
IUUC-Dor-030938	Dipodomys ordii	34.32	1.00e-62	233.00
IUUC-Dse-031416	Dothistroma septosporum	28.94	4.00e-71	261.00
IUUC-Dme-031946	Drosophila melanogaster	32.50	4.00e-65	241.00
IUUC-Ete-033041	Echinops telfairi	29.02	2.00e-37	149.00
IUUC-Eca-033828	Equus caballus	36.52	3.00e-65	241.00
IUUC-Eeu-035201	Erinaceus europaeus	31.19	1.00e-42	166.00
IUUC-Fca-035907	Felis catus	36.28	9.00e-65	239.00
IUUC-Fal-037389	Ficedula albicollis	36.75	6.00e-67	247.00
IUUC-Fox-037788	Fusarium oxysporum	31.72	9.00e-79	286.00
IUUC-Fso-038088	Fusarium solani	34.24	2.00e-78	285.00
IUUC-Gmo-039412	Gadus morhua	32.29	4.00e-65	241.00
IUUC-Ggr-039941	Gaeumannomyces graminis	37.63	2.00e-75	275.00
IUUC-Gga-040310	Gallus gallus	36.99	6.00e-67	247.00
IUUC-Gac-042088	Gasterosteus aculeatus	31.70	2.00e-66	245.00
IUUC-Gma-042819	Glycine max	34.43	1.00e-59	222.00
IUUC-Ggo-045031	Gorilla gorilla	36.75	2.00e-65	242.00
IUUC-Hsa-045880	Homo sapiens	36.75	2.00e-65	242.00
IUUC-Hvu-047770	Hordeum vulgare	36.81	2.00e-72	264.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	35.31	2.00e-63	234.00
IUUC-Lch-050664	Latimeria chalumnae	32.82	7.00e-65	240.00
IUUC-Lpe-051428	Leersia perrieri	35.08	2.00e-63	235.00
IUUC-Loc-052218	Lepisosteus oculatus	36.47	1.00e-65	243.00
IUUC-Lma-053096	Leptosphaeria maculans	31.53	1.00e-79	289.00
IUUC-Laf-053902	Loxodonta africana	32.74	4.00e-65	241.00
IUUC-Mcc-055127	Macaca mulatta	36.75	2.00e-65	242.00
IUUC-Meu-056527	Macropus eugenii	34.98	7.00e-52	197.00
IUUC-Mor-057021	Magnaporthe oryzae	31.01	1.00e-68	253.00
IUUC-Mpo-057570	Magnaporthe poae	37.42	5.00e-73	267.00
IUUC-Mtr-058154	Medicago truncatula	34.91	6.00e-62	230.00
IUUC-Mla-059124	Melampsora laricipopulina	38.82	6.00e-68	249.00
IUUC-Mga-059581	Meleagris gallopavo	36.75	8.00e-67	246.00
IUUC-Mvi-060445	Microbotryum violaceum	34.55	3.00e-83	301.00
IUUC-Mmr-061360	Microcebus murinus	36.52	5.00e-65	240.00
IUUC-Mdo-062194	Monodelphis domestica	36.99	2.00e-66	245.00
IUUC-Mmu-064189	Mus musculus	36.52	2.00e-65	241.00
IUUC-Mac-065275	Musa acuminata	36.07	6.00e-70	256.00
IUUC-Mpu-066439	Mustela putorius furo	36.28	7.00e-65	240.00
IUUC-Mlu-068228	Myotis lucifugus	36.75	6.00e-66	243.00
IUUC-Nfi-068280	Neosartorya fischeri	38.38	1.00e-76	280.00
IUUC-Ncr-068869	Neurospora crassa	31.91	2.00e-79	288.00
IUUC-Nle-069687	Nomascus leucogenys	36.75	8.00e-66	243.00
IUUC-Opr-070554	Ochotona princeps	32.26	3.00e-64	238.00
IUUC-Ont-071836	Oreochromis niloticus	33.79	6.00e-68	250.00
IUUC-Oan-072800	Ornithorhynchus anatinus	36.99	2.00e-67	249.00
IUUC-Ocu-074587	Oryctolagus cuniculus	36.75	1.00e-65	242.00
IUUC-Oba-075006	Oryza barthii	36.94	7.00e-74	270.00
IUUC-Obr-076133	Oryza brachyantha	37.18	7.00e-74	270.00
IUUC-Ogl-077003	Oryza glaberrima	36.94	6.00e-74	270.00
IUUC-Ogu-078947	Oryza glumaepatula	36.04	1.00e-73	269.00
IUUC-Oin-079407	Oryza indica	34.35	2.00e-63	235.00
IUUC-Olo-080475	Oryza longistaminata	36.94	2.00e-73	269.00
IUUC-Ome-081342	Oryza meridionalis	34.08	8.00e-64	236.00
IUUC-Oni-082385	Oryza nivara	36.04	1.00e-73	269.00
IUUC-Opu-083176	Oryza punctata	36.94	2.00e-73	268.00
IUUC-Oru-084554	Oryza rufipogon	34.84	2.00e-63	235.00
IUUC-Osa-085355	Oryza sativa	36.94	2.00e-73	268.00
IUUC-Ola-087209	Oryzias latipes	33.98	2.00e-69	255.00
IUUC-Olu-087699	Ostreococcus lucimarinus	36.43	2.00e-58	217.00
IUUC-Oga-088776	Otolemur garnettii	36.75	2.00e-65	242.00
IUUC-Oar-089441	Ovis aries	36.52	7.00e-66	243.00
IUUC-Ptr-091273	Pan troglodytes	36.75	2.00e-65	242.00
IUUC-Pan-091981	Papio anubis	36.75	2.00e-65	242.00
IUUC-Psi-093251	Pelodiscus sinensis	32.37	2.00e-55	209.00
IUUC-Pma-094738	Petromyzon marinus	36.97	2.00e-64	239.00
IUUC-Pno-095132	Phaeosphaeria nodorum	28.81	2.00e-57	215.00
IUUC-Ppa-095544	Physcomitrella patens	36.85	1.00e-70	259.00
IUUC-Pfo-097511	Poecilia formosa	37.53	2.00e-67	248.00
IUUC-Pab-098570	Pongo abelii	32.29	4.00e-65	241.00
IUUC-Pop-098928	Populus trichocarpa	35.15	1.00e-60	226.00
IUUC-Pca-100987	Procavia capensis	36.57	1.00e-61	229.00
IUUC-Ppe-101281	Prunus persica	32.20	7.00e-65	240.00
IUUC-Pva-102887	Pteropus vampyrus	32.52	1.00e-65	243.00
IUUC-Pgr-103513	Puccinia graminis	33.85	7.00e-72	263.00
IUUC-Ptt-103967	Puccinia triticina	32.08	2.00e-61	228.00
IUUC-Pte-104105	Pyrenophora teres	31.66	1.00e-80	292.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	31.52	4.00e-78	284.00
IUUC-Rno-106028	Rattus norvegicus	29.78	5.00e-51	194.00
IUUC-Sce-106446	Saccharomyces cerevisiae	39.91	9.00e-76	276.00
IUUC-Sha-107331	Sarcophilus harrisii	32.52	3.00e-65	241.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	32.53	5.00e-70	257.00
IUUC-Spo-108097	Schizosaccharomyces pombe	32.99	2.00e-67	248.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	31.16	7.00e-72	263.00
IUUC-Smo-108853	Selaginella moellendorffii	36.14	5.00e-68	250.00
IUUC-Sit-110457	Setaria italica	36.71	5.00e-65	240.00
IUUC-Sly-111362	Solanum lycopersicum	35.87	2.00e-62	231.00
IUUC-Sbi-113882	Sorghum bicolor	36.00	1.00e-63	236.00
IUUC-Sre-115038	Sporisorium reilianum	40.24	7.00e-77	280.00
IUUC-Ssc-116103	Sus scrofa	32.29	1.00e-64	239.00
IUUC-Tgu-116729	Taeniopygia guttata	36.75	1.00e-66	246.00
IUUC-Tru-118068	Takifugu rubripes	38.10	2.00e-67	249.00
IUUC-Tsy-118942	Tarsius syrichta	38.70	8.00e-46	177.00
IUUC-Tni-120850	Tetraodon nigroviridis	35.40	2.00e-64	237.00
IUUC-Tca-121737	Theobroma cacao	36.32	3.00e-70	258.00
IUUC-Tre-121892	Trichoderma reesei	41.11	1.00e-75	276.00
IUUC-Tvi-122354	Trichoderma virens	35.18	2.00e-78	285.00
IUUC-Tae-125466	Triticum aestivum	36.81	2.00e-72	265.00
IUUC-Tur-126086	Triticum urartu	36.38	1.00e-59	223.00
IUUC-Tme-127102	Tuber melanosporum	34.35	8.00e-79	286.00
IUUC-Tbe-127351	Tupaia belangeri	35.64	4.00e-50	191.00
IUUC-Ttr-129269	Tursiops truncatus	32.29	8.00e-65	239.00
IUUC-Uma-129343	Ustilago maydis	41.43	4.00e-81	294.00
IUUC-Vda-129748	Verticillium dahliae	30.56	3.00e-69	254.00
IUUC-Vvi-131234	Vitis vinifera	35.85	2.00e-61	229.00
IUUC-Xtr-132094	Xenopus tropicalis	36.99	9.00e-67	246.00
IUUC-Xma-133923	Xiphophorus maculatus	37.53	2.00e-67	248.00
IUUC-Yli-134496	Yarrowia lipolytica	34.81	1.00e-81	295.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence