iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058154

Ensembl Protein ID

AES64909

UniProt Accession

G7IL24; A0A0C3V0M0; G7IL24_MEDTR

Genbank Protein ID

AES64909.2

Protein Name

E3 ubiquitin-protein ligase UPL6

Genbank Nucleotide ID

CM001218

Gene Name

MTR_2g033040

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_2g033040	AES64909	AES64909

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.90e-108	362.7	684	1024

Active Site

Position(s)	Description	Evidence
992	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsks 95
           ++dl+  ++v+fv+     E+g+d gG++++f+++++++ ++ ++glf  +e+ ++ l+pnp sg+ +++hl++F+flG+ll+ka+++g l+dlp++++
   Q: 684  EDDLRGLIRVTFVNefgveEAGIDGGGIFKDFMENITRASFDVQYGLF--KETADHLLYPNPGSGMIHEQHLQFFHFLGTLLAKAMFEGILVDLPFATF 780
           679999999*****9999999***************************..5566889999999999999****************************** PP
   S: 96   fyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafr 194
           f+++l +k   l+dl+++dpely++l ++k++ e di++  l+l f + ++++ge++eeeL+pgG+n +VtneN   +++lv+++rl+++i++q  +f 
   Q: 781  FLSKLKQKHNYLNDLPSLDPELYRHLIFLKRY-EGDISD--LELYFVILNNEYGEQTEEELLPGGKNLRVTNENVITFIHLVANHRLNSQIRQQSSHFL 876
           *********999********************.667777..69999999************************************************** PP
   S: 195  eGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk. 291
           +Gf+++i+++++++F+e+el+lli+G+ +++dv+dl+++t+y g y++++ +i++Fwevl++fs+e++k+fL+FvTg+sr Pl Gf++l+p lf+i++ 
   Q: 877  RGFQQLIQKDWIDMFNEHELQLLISGSlDSLDVDDLREHTNYAGTYHSEHDVIEMFWEVLKGFSMENKKKFLKFVTGCSRGPLLGFRYLEP-LFCIQRa 974
           ******************************************************************************************5.5999999 PP
   S: 292  .....dasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
                +    drlP++ TC+n+LkLP+Y sk+++++kLlyAi++ +gF+ls
   Q: 975  ggnatED-AlDRLPTAATCMNLLKLPPYRSKDQMESKLLYAINSDAGFDLS 1024
           **96333.36**************************************985 PP

Organism

Medicago truncatula

Protein Sequence
(Fasta)

MFFSGDPSNR KRVDLGGRSS KERDRKNLLE QTRLERNRRL WLRQQNSAAL RIQKCFRAKK 60
VVRTEQSKLR QKFLHIYGKN CLNVDRKAFG PDSDFLRQFL YFFNAENHDD FLVLLQICRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAACCGAAGA TTCCTATTTT TTCTCTCTTC TTTTCACATA CACTTTTCTC CGTATAAATA 60
CTACACAAAT ATCAATCAAT ATTCAATTCA CTCTCTCTCA TTTCATTTCC TATTCACAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

mtr:MTR_2g033040

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000469	Aegilops tauschii	55.01	0.00e+00	1005.00
IUUC-Aml-001355	Ailuropoda melanoleuca	38.88	2.00e-106	379.00
IUUC-Atr-002669	Amborella trichopoda	60.39	0.00e+00	1253.00
IUUC-Apl-003731	Anas platyrhynchos	39.24	7.00e-110	391.00
IUUC-Aca-005248	Anolis carolinensis	39.06	1.00e-109	390.00
IUUC-Aly-005768	Arabidopsis lyrata	67.86	0.00e+00	1456.00
IUUC-Ath-006576	Arabidopsis thaliana	67.57	0.00e+00	1456.00
IUUC-Ago-007748	Ashbya gossypii	40.71	7.00e-75	275.00
IUUC-Ame-010769	Astyanax mexicanus	42.90	5.00e-75	275.00
IUUC-Bgr-012269	Blumeria graminis	38.53	4.00e-74	271.00
IUUC-Bta-012841	Bos taurus	39.60	2.00e-109	390.00
IUUC-Bci-013743	Botrytis cinerea	38.14	2.00e-82	300.00
IUUC-Bdi-014123	Brachypodium distachyon	59.24	0.00e+00	1165.00
IUUC-Bol-015467	Brassica oleracea	66.02	0.00e+00	1387.00
IUUC-Bra-017723	Brassica rapa	66.21	0.00e+00	1389.00
IUUC-Cfa-021031	Canis familiaris	38.88	3.00e-107	382.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	47.31	6.00e-101	360.00
IUUC-Csa-024107	Chlorocebus sabaeus	38.70	8.00e-107	381.00
IUUC-Cho-024750	Choloepus hoffmanni	48.54	5.00e-94	338.00
IUUC-Cme-027265	Cyanidioschyzon merolae	40.49	5.00e-105	375.00
IUUC-Dre-028196	Danio rerio	46.84	1.00e-106	380.00
IUUC-Dno-029024	Dasypus novemcinctus	38.88	3.00e-107	382.00
IUUC-Ete-033041	Echinops telfairi	43.93	3.00e-69	256.00
IUUC-Eca-033828	Equus caballus	39.06	5.00e-108	385.00
IUUC-Fca-035907	Felis catus	39.06	1.00e-107	384.00
IUUC-Fal-037389	Ficedula albicollis	39.06	2.00e-109	389.00
IUUC-Ggr-039941	Gaeumannomyces graminis	38.39	8.00e-82	298.00
IUUC-Gga-040310	Gallus gallus	39.24	2.00e-109	389.00
IUUC-Gma-042836	Glycine max	85.66	0.00e+00	1795.00
IUUC-Ggo-045031	Gorilla gorilla	38.88	3.00e-107	382.00
IUUC-Hsa-045880	Homo sapiens	38.88	3.00e-107	382.00
IUUC-Hvu-047770	Hordeum vulgare	62.62	0.00e+00	997.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	44.36	2.00e-96	345.00
IUUC-Kpa-049307	Komagataella pastoris	34.91	2.00e-68	253.00
IUUC-Lpe-051428	Leersia perrieri	55.87	0.00e+00	1135.00
IUUC-Loc-052218	Lepisosteus oculatus	46.02	3.00e-105	375.00
IUUC-Lma-053096	Leptosphaeria maculans	39.70	5.00e-82	299.00
IUUC-Mcc-055127	Macaca mulatta	38.88	3.00e-107	382.00
IUUC-Mla-059124	Melampsora laricipopulina	43.81	5.00e-93	333.00
IUUC-Mga-059581	Meleagris gallopavo	39.24	2.00e-109	390.00
IUUC-Mmr-061360	Microcebus murinus	39.24	2.00e-108	386.00
IUUC-Mdo-062194	Monodelphis domestica	38.70	7.00e-108	384.00
IUUC-Mmu-064189	Mus musculus	39.06	3.00e-106	379.00
IUUC-Mac-065275	Musa acuminata	60.86	0.00e+00	1071.00
IUUC-Mpu-066439	Mustela putorius furo	39.06	3.00e-108	385.00
IUUC-Mlu-068228	Myotis lucifugus	39.42	3.00e-109	389.00
IUUC-Ont-071836	Oreochromis niloticus	46.75	2.00e-107	383.00
IUUC-Oan-072800	Ornithorhynchus anatinus	41.05	9.00e-109	387.00
IUUC-Ocu-074587	Oryctolagus cuniculus	39.42	4.00e-108	385.00
IUUC-Oba-075006	Oryza barthii	59.75	0.00e+00	1239.00
IUUC-Obr-076133	Oryza brachyantha	59.75	0.00e+00	1238.00
IUUC-Ogl-077003	Oryza glaberrima	59.75	0.00e+00	1238.00
IUUC-Ogu-078947	Oryza glumaepatula	59.98	0.00e+00	1239.00
IUUC-Oin-079407	Oryza indica	58.20	0.00e+00	1187.00
IUUC-Olo-080475	Oryza longistaminata	59.85	0.00e+00	1240.00
IUUC-Ome-081342	Oryza meridionalis	57.58	0.00e+00	1172.00
IUUC-Oni-082385	Oryza nivara	59.98	0.00e+00	1237.00
IUUC-Opu-083176	Oryza punctata	58.45	0.00e+00	1199.00
IUUC-Oru-084554	Oryza rufipogon	57.83	0.00e+00	1181.00
IUUC-Osa-085355	Oryza sativa	60.04	0.00e+00	1242.00
IUUC-Ola-087209	Oryzias latipes	46.27	3.00e-107	382.00
IUUC-Olu-087699	Ostreococcus lucimarinus	47.68	2.00e-101	361.00
IUUC-Oga-088776	Otolemur garnettii	38.70	9.00e-107	381.00
IUUC-Oar-089441	Ovis aries	39.60	1.00e-109	390.00
IUUC-Ptr-091273	Pan troglodytes	38.88	2.00e-107	383.00
IUUC-Pan-091981	Papio anubis	38.88	2.00e-107	383.00
IUUC-Pno-095132	Phaeosphaeria nodorum	37.31	3.00e-61	229.00
IUUC-Ppa-095682	Physcomitrella patens	50.00	0.00e+00	940.00
IUUC-Pfo-097511	Poecilia formosa	46.99	4.00e-108	385.00
IUUC-Pop-098928	Populus trichocarpa	71.15	0.00e+00	1479.00
IUUC-Pca-100987	Procavia capensis	48.90	2.00e-100	360.00
IUUC-Ppe-102040	Prunus persica	74.30	0.00e+00	1518.00
IUUC-Ptt-103967	Puccinia triticina	41.23	6.00e-82	298.00
IUUC-Pte-104105	Pyrenophora teres	39.40	8.00e-83	301.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	39.40	1.00e-82	300.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	35.87	1.00e-102	367.00
IUUC-Spo-108097	Schizosaccharomyces pombe	37.39	4.00e-101	362.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	39.03	4.00e-81	296.00
IUUC-Smo-109007	Selaginella moellendorffii	46.39	0.00e+00	915.00
IUUC-Sit-110457	Setaria italica	60.10	0.00e+00	1233.00
IUUC-Sly-111362	Solanum lycopersicum	69.28	0.00e+00	1434.00
IUUC-Sar-113687	Sorex araneus	42.11	1.00e-60	227.00
IUUC-Sbi-113882	Sorghum bicolor	59.57	0.00e+00	1201.00
IUUC-Tgu-116729	Taeniopygia guttata	38.88	2.00e-108	386.00
IUUC-Tru-118068	Takifugu rubripes	47.71	4.00e-109	389.00
IUUC-Tsy-118942	Tarsius syrichta	50.57	2.00e-72	267.00
IUUC-Tni-120732	Tetraodon nigroviridis	46.27	1.00e-102	367.00
IUUC-Tca-121737	Theobroma cacao	74.03	0.00e+00	1569.00
IUUC-Tvi-122354	Trichoderma virens	31.07	4.00e-87	316.00
IUUC-Tae-125229	Triticum aestivum	59.32	0.00e+00	1244.00
IUUC-Tme-127102	Tuber melanosporum	39.07	3.00e-82	300.00
IUUC-Tbe-127351	Tupaia belangeri	37.12	1.00e-88	320.00
IUUC-Uma-129343	Ustilago maydis	45.19	2.00e-98	353.00
IUUC-Vvi-131234	Vitis vinifera	73.11	0.00e+00	1532.00
IUUC-Xma-133923	Xiphophorus maculatus	46.99	3.00e-108	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence