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Tag Content
UUCD2 ID IUUC-Cfa-020553
UUCD1 version UUC-CaF-00303
Ensembl Protein ID ENSCAFP00000014526.3
UniProt Accession E2RDC4; E2RDC4_CANLF
Genbank Protein ID ENSCAFP00000014526
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03015479
Gene Name BTRC
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000009879.3 ENSCAFT00000015696.3 ENSCAFP00000014526.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 5.80e-59 193.7 504 539
UBD/Beta-Prp 6.80e-69 232.6 418 582
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v+c++f d +++vsG++Dg+ikvWDl    ++
   Q: 504  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLVAALDP 539
           8**********.44****************9876665 PP
   

   UBD/Beta-Prp
   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl+ +
   Q: 418  LRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLR-V 501
           445569*************9..8**************************************..************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           l+gh+++v+c++++   + +vsG++D+++++Wdl         +   +lrtl + h ++v  l+fd+  +++vs s+d t+ +wd+
   Q: 502  LEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLvaaldprapAGTLCLRTLVE-HSGRVFRLQFDE--FQIVSSSHDDTILIWDF 582
           **************9..*************************877889****98.************..99**************7 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MDPAEAVLQE KALKFMCSMP RSLWLGCSSL ADSMPSLRCL YNPGTGALTA FQNSSEREDC 60
NNGEPPRKII PEKNSLRQTY NSCARLCLNQ ETVCLASTAM KTENCVAKTK LANGTSSMIV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020553|E3,WD_repeat;UBD,Beta-Prp|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGACCCGG CCGAGGCGGT GCTGCAGGAA AAAGCGCTCA AGTTTATGGT GAGGAGGAGG 60
CGCAGGCCGG GGAACGGTGG AGGCGGTGGC GTTGGCGACG TTGCTGAGGC TCGGGCCTGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020553|E3,WD_repeat;UBD,Beta-Prp|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0071407--P:cellular response to organic cyclic compound
GO:0033598--P:mammary gland epithelial cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0042753--P:positive regulation of circadian rhythm
GO:0045862--P:positive regulation of proteolysis
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006470--P:protein dephosphorylation
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0060828--P:regulation of canonical Wnt signaling pathway
GO:0051726--P:regulation of cell cycle
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061136--P:regulation of proteasomal protein catabolic process
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001961 Ailuropoda melanoleuca 99.83 0.00e+00 1261.00
IUUC-Apl-003437 Anas platyrhynchos 98.40 0.00e+00 1021.00
IUUC-Aca-004410 Anolis carolinensis 92.68 0.00e+00 1206.00
IUUC-Acl-008355 Aspergillus clavatus 29.69 6.00e-51 195.00
IUUC-Afl-008580 Aspergillus flavus 27.46 2.00e-44 174.00
IUUC-Afu-008790 Aspergillus fumigatus 36.99 3.00e-38 153.00
IUUC-Ani-009324 Aspergillus nidulans 29.40 1.00e-48 187.00
IUUC-Aor-009916 Aspergillus oryzae 28.42 2.00e-47 184.00
IUUC-Ate-010492 Aspergillus terreus 30.18 4.00e-50 192.00
IUUC-Bgr-012194 Blumeria graminis 32.52 2.00e-54 207.00
IUUC-Bta-013453 Bos taurus 93.88 0.00e+00 1167.00
IUUC-Bci-013685 Botrytis cinerea 31.58 5.00e-55 209.00
IUUC-Cel-018392 Caenorhabditis elegans 63.71 0.00e+00 635.00
IUUC-Cja-019121 Callithrix jacchus 95.21 0.00e+00 1188.00
IUUC-Cpo-022126 Cavia porcellus 97.14 0.00e+00 1170.00
IUUC-Csa-023688 Chlorocebus sabaeus 99.83 0.00e+00 1261.00
IUUC-Cin-025188 Ciona intestinalis 80.50 0.00e+00 827.00
IUUC-Csv-026020 Ciona savignyi 76.54 0.00e+00 790.00
IUUC-Cgl-026429 Colletotrichum gloeosporioides 33.55 3.00e-61 229.00
IUUC-Dno-029484 Dasypus novemcinctus 93.72 0.00e+00 1168.00
IUUC-Dor-031010 Dipodomys ordii 92.87 0.00e+00 1101.00
IUUC-Dme-031885 Drosophila melanogaster 80.41 0.00e+00 820.00
IUUC-Ete-032978 Echinops telfairi 86.72 0.00e+00 1055.00
IUUC-Eca-033374 Equus caballus 98.99 0.00e+00 1225.00
IUUC-Eeu-034760 Erinaceus europaeus 78.51 0.00e+00 948.00
IUUC-Fca-035427 Felis catus 95.70 0.00e+00 1193.00
IUUC-Fal-037530 Ficedula albicollis 98.47 0.00e+00 1209.00
IUUC-Fox-037978 Fusarium oxysporum 33.55 2.00e-62 233.00
IUUC-Fso-038077 Fusarium solani 32.75 4.00e-57 216.00
IUUC-Ggr-039974 Gaeumannomyces graminis 32.08 7.00e-56 212.00
IUUC-Gga-041087 Gallus gallus 94.90 0.00e+00 1230.00
IUUC-Ggo-045369 Gorilla gorilla 99.46 0.00e+00 1150.00
IUUC-Hsa-045962 Homo sapiens 99.83 0.00e+00 1261.00
IUUC-Itr-047872 Ictidomys tridecemlineatus 99.78 0.00e+00 942.00
IUUC-Lch-050285 Latimeria chalumnae 89.98 0.00e+00 943.00
IUUC-Loc-052686 Lepisosteus oculatus 92.40 0.00e+00 1169.00
IUUC-Lma-053289 Leptosphaeria maculans 38.43 8.00e-48 185.00
IUUC-Laf-054022 Loxodonta africana 98.99 0.00e+00 1225.00
IUUC-Mcc-055782 Macaca mulatta 99.83 0.00e+00 1224.00
IUUC-Meu-056078 Macropus eugenii 84.41 0.00e+00 898.00
IUUC-Mor-057283 Magnaporthe oryzae 33.26 9.00e-59 221.00
IUUC-Mpo-057540 Magnaporthe poae 32.30 1.00e-56 214.00
IUUC-Mla-058989 Melampsora laricipopulina 40.88 4.00e-61 228.00
IUUC-Mga-059388 Meleagris gallopavo 97.17 0.00e+00 1216.00
IUUC-Mmr-060969 Microcebus murinus 100.00 0.00e+00 1263.00
IUUC-Mdo-063041 Monodelphis domestica 99.17 0.00e+00 1222.00
IUUC-Mmu-064096 Mus musculus 98.84 0.00e+00 1250.00
IUUC-Mpu-066875 Mustela putorius furo 99.82 0.00e+00 1151.00
IUUC-Mlu-067621 Myotis lucifugus 99.20 0.00e+00 1038.00
IUUC-Nfi-068263 Neosartorya fischeri 29.50 4.00e-50 192.00
IUUC-Ncr-068639 Neurospora crassa 34.82 3.00e-45 177.00
IUUC-Nle-069548 Nomascus leucogenys 99.67 0.00e+00 1259.00
IUUC-Opr-071194 Ochotona princeps 93.88 0.00e+00 1167.00
IUUC-Oan-072867 Ornithorhynchus anatinus 95.51 0.00e+00 1230.00
IUUC-Ocu-074246 Oryctolagus cuniculus 100.00 0.00e+00 1263.00
IUUC-Oga-088244 Otolemur garnettii 99.80 0.00e+00 1039.00
IUUC-Oar-089199 Ovis aries 99.21 0.00e+00 1048.00
IUUC-Ptr-090475 Pan troglodytes 79.54 0.00e+00 937.00
IUUC-Pan-092826 Papio anubis 99.83 0.00e+00 1261.00
IUUC-Psi-093485 Pelodiscus sinensis 95.79 0.00e+00 1180.00
IUUC-Pma-094315 Petromyzon marinus 80.79 0.00e+00 894.00
IUUC-Pab-097680 Pongo abelii 99.34 0.00e+00 1255.00
IUUC-Pca-100843 Procavia capensis 92.89 0.00e+00 1137.00
IUUC-Pva-102793 Pteropus vampyrus 89.59 0.00e+00 1097.00
IUUC-Pgr-103331 Puccinia graminis 37.69 3.00e-52 199.00
IUUC-Ptt-103853 Puccinia triticina 32.08 7.00e-61 228.00
IUUC-Pte-104392 Pyrenophora teres 37.37 1.00e-47 184.00
IUUC-Pyt-104678 Pyrenophora triticirepentis 37.72 7.00e-48 186.00
IUUC-Rno-105304 Rattus norvegicus 98.64 0.00e+00 1211.00
IUUC-Sha-107454 Sarcophilus harrisii 94.64 0.00e+00 1205.00
IUUC-Sar-113471 Sorex araneus 78.35 0.00e+00 927.00
IUUC-Sre-114916 Sporisorium reilianum 33.71 1.00e-45 178.00
IUUC-Ssc-115490 Sus scrofa 99.80 0.00e+00 1055.00
IUUC-Tgu-117445 Taeniopygia guttata 98.35 0.00e+00 1243.00
IUUC-Tsy-118983 Tarsius syrichta 95.42 0.00e+00 1166.00
IUUC-Tre-122207 Trichoderma reesei 33.63 7.00e-56 211.00
IUUC-Tvi-122344 Trichoderma virens 34.00 8.00e-56 211.00
IUUC-Tme-127141 Tuber melanosporum 35.86 8.00e-65 241.00
IUUC-Tbe-128146 Tupaia belangeri 90.08 0.00e+00 1071.00
IUUC-Ttr-128946 Tursiops truncatus 99.83 0.00e+00 1262.00
IUUC-Uma-129491 Ustilago maydis 33.42 7.00e-47 182.00
IUUC-Vda-129941 Verticillium dahliae 32.23 2.00e-57 217.00
IUUC-Vpa-130709 Vicugna pacos 98.02 0.00e+00 1229.00
IUUC-Xtr-132861 Xenopus tropicalis 92.37 0.00e+00 1165.00
Created Date 25-Jun-2017

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