iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-034001

Ensembl Protein ID

ENSECAP00000010788.1

UniProt Accession

F6SFE1; F6SFE1_HORSE

Protein Name

Uncharacterized protein

Gene Name

NPLOC4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000012622.1	ENSECAT00000013577.1	ENSECAP00000010788.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	1.20e-12	47.3	581	608

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 2    eaqWaCsaCTflNePeavkCemCsrpRg 29
           +a+WaC++CTf+N+P +++CemCs pR+
   Q: 581  AAMWACQHCTFMNQPGTGHCEMCSLPRT 608
           689***********************95 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

LVETLIVRVQ SPDGVKRITA TKRETAATFL KKVAKEFGFQ NNGFSVYINR NKTGEITASS 60
NKSLNLLKIK HGDLLFLFPS SLAGPSSEME TSTPPGFKAF GAPNVVEDEI DQYLSKQDGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTGTAGAAA CTTTGGTATC GCAAGGGGAA GGGTGGGGTT TGGCTTTAAG TTTCGGTCAC 60
CCATATGATG TTGGAAGACT GCAGATGTTA GTGTTAATAA TAGATCAGGA CCTTACTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR016563--Npl4
IPR007717--NPL4_C
IPR024682--Npl4_Ub-like_dom
IPR007716--NPL4_Zn-bd_put
IPR029071--Ubiquitin-rel_dom
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF05021--NPL4
PF11543--UN_NPL4
PF05020--zf-NPL4

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0005634--C:nucleus
GO:0036501--C:UFD1-NPL4 complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0043130--F:ubiquitin binding
GO:0031625--F:ubiquitin protein ligase binding
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000460	Aegilops tauschii	27.68	9.00e-15	74.70
IUUC-Aml-002268	Ailuropoda melanoleuca	97.18	0.00e+00	1211.00
IUUC-Atr-002939	Amborella trichopoda	28.41	7.00e-19	88.20
IUUC-Apl-003496	Anas platyrhynchos	89.54	0.00e+00	1087.00
IUUC-Aca-005230	Anolis carolinensis	90.64	0.00e+00	1167.00
IUUC-Aly-006056	Arabidopsis lyrata	29.82	1.00e-22	100.00
IUUC-Ath-006993	Arabidopsis thaliana	27.57	6.00e-21	95.10
IUUC-Ago-007954	Ashbya gossypii	35.91	7.00e-79	288.00
IUUC-Acl-008208	Aspergillus clavatus	33.81	2.00e-91	329.00
IUUC-Afl-008574	Aspergillus flavus	35.86	1.00e-88	320.00
IUUC-Afu-008825	Aspergillus fumigatus	34.71	3.00e-96	345.00
IUUC-Ani-009495	Aspergillus nidulans	39.49	6.00e-93	335.00
IUUC-Ang-009762	Aspergillus niger	33.72	1.00e-87	317.00
IUUC-Aor-010199	Aspergillus oryzae	35.32	7.00e-87	314.00
IUUC-Ate-010592	Aspergillus terreus	37.69	7.00e-92	331.00
IUUC-Ame-011587	Astyanax mexicanus	72.18	4.00e-104	372.00
IUUC-Bgr-012124	Blumeria graminis	32.69	4.00e-88	318.00
IUUC-Bta-013312	Bos taurus	96.88	0.00e+00	1244.00
IUUC-Bci-013648	Botrytis cinerea	32.85	6.00e-95	341.00
IUUC-Bdi-014326	Brachypodium distachyon	28.36	2.00e-15	77.00
IUUC-Bol-016294	Brassica oleracea	28.45	1.00e-20	94.40
IUUC-Bra-017023	Brassica rapa	28.45	6.00e-21	95.10
IUUC-Cel-018713	Caenorhabditis elegans	43.63	7.00e-130	457.00
IUUC-Cja-018869	Callithrix jacchus	97.20	0.00e+00	1227.00
IUUC-Cfa-020757	Canis familiaris	97.53	0.00e+00	1230.00
IUUC-Cpo-022390	Cavia porcellus	97.68	0.00e+00	1207.00
IUUC-Csa-023366	Chlorocebus sabaeus	97.70	0.00e+00	1258.00
IUUC-Cho-024455	Choloepus hoffmanni	79.48	0.00e+00	842.00
IUUC-Cin-025638	Ciona intestinalis	48.38	4.00e-145	507.00
IUUC-Csv-026310	Ciona savignyi	45.21	2.00e-132	466.00
IUUC-Cgl-026685	Colletotrichum gloeosporioides	33.71	1.00e-89	323.00
IUUC-Cne-026794	Cryptococcus neoformans	29.63	3.00e-72	266.00
IUUC-Cme-027248	Cyanidioschyzon merolae	26.90	1.00e-15	77.40
IUUC-Dre-027689	Danio rerio	80.70	0.00e+00	1048.00
IUUC-Dno-030004	Dasypus novemcinctus	95.72	0.00e+00	1216.00
IUUC-Dor-030585	Dipodomys ordii	97.13	0.00e+00	982.00
IUUC-Dse-031202	Dothistroma septosporum	33.05	1.00e-88	320.00
IUUC-Dme-032092	Drosophila melanogaster	48.25	1.00e-176	613.00
IUUC-Ete-033009	Echinops telfairi	96.53	2.00e-99	355.00
IUUC-Eeu-034485	Erinaceus europaeus	81.33	0.00e+00	834.00
IUUC-Fca-036128	Felis catus	96.88	0.00e+00	1189.00
IUUC-Fal-037523	Ficedula albicollis	90.97	0.00e+00	1172.00
IUUC-Fox-037802	Fusarium oxysporum	34.00	3.00e-95	342.00
IUUC-Fso-038152	Fusarium solani	33.39	1.00e-94	340.00
IUUC-Gmo-038486	Gadus morhua	74.38	0.00e+00	952.00
IUUC-Ggr-039916	Gaeumannomyces graminis	37.24	3.00e-85	309.00
IUUC-Gga-041208	Gallus gallus	92.12	0.00e+00	1192.00
IUUC-Gac-042304	Gasterosteus aculeatus	78.01	0.00e+00	983.00
IUUC-Gma-044178	Glycine max	26.95	1.00e-15	77.80
IUUC-Ggo-045236	Gorilla gorilla	94.53	0.00e+00	1191.00
IUUC-Hsa-046334	Homo sapiens	97.53	0.00e+00	1255.00
IUUC-Hvu-047323	Hordeum vulgare	26.70	1.00e-08	52.80
IUUC-Itr-047878	Ictidomys tridecemlineatus	97.29	0.00e+00	728.00
IUUC-Lch-050302	Latimeria chalumnae	83.58	0.00e+00	1068.00
IUUC-Lpe-051362	Leersia perrieri	28.57	1.00e-17	84.30
IUUC-Loc-052548	Lepisosteus oculatus	82.20	0.00e+00	1027.00
IUUC-Lma-053092	Leptosphaeria maculans	34.16	2.00e-95	343.00
IUUC-Laf-053911	Loxodonta africana	96.39	0.00e+00	1236.00
IUUC-Mcc-055830	Macaca mulatta	97.83	0.00e+00	1235.00
IUUC-Meu-056460	Macropus eugenii	58.73	7.00e-149	520.00
IUUC-Mor-057189	Magnaporthe oryzae	37.16	8.00e-88	318.00
IUUC-Mpo-057366	Magnaporthe poae	37.97	1.00e-85	310.00
IUUC-Mtr-057834	Medicago truncatula	26.76	2.00e-17	83.20
IUUC-Mla-059190	Melampsora laricipopulina	33.14	1.00e-85	310.00
IUUC-Mga-060036	Meleagris gallopavo	92.22	0.00e+00	1182.00
IUUC-Mvi-060275	Microbotryum violaceum	35.11	6.00e-79	288.00
IUUC-Mmr-061300	Microcebus murinus	98.18	0.00e+00	1243.00
IUUC-Mdo-062911	Monodelphis domestica	95.79	0.00e+00	1056.00
IUUC-Mmu-063916	Mus musculus	97.20	0.00e+00	1221.00
IUUC-Mac-065601	Musa acuminata	26.75	2.00e-11	63.50
IUUC-Mpu-065912	Mustela putorius furo	96.69	0.00e+00	1211.00
IUUC-Mlu-067965	Myotis lucifugus	95.07	0.00e+00	1193.00
IUUC-Nfi-068465	Neosartorya fischeri	35.04	6.00e-97	348.00
IUUC-Ncr-068936	Neurospora crassa	33.33	2.00e-91	329.00
IUUC-Nle-069570	Nomascus leucogenys	97.37	0.00e+00	1250.00
IUUC-Opr-071097	Ochotona princeps	92.20	0.00e+00	920.00
IUUC-Ont-071430	Oreochromis niloticus	79.55	0.00e+00	1027.00
IUUC-Oan-073709	Ornithorhynchus anatinus	82.21	0.00e+00	794.00
IUUC-Ocu-074875	Oryctolagus cuniculus	92.38	0.00e+00	1152.00
IUUC-Oba-075214	Oryza barthii	27.34	1.00e-17	84.00
IUUC-Obr-076758	Oryza brachyantha	28.41	2.00e-17	82.80
IUUC-Ogl-077665	Oryza glaberrima	27.34	1.00e-17	84.00
IUUC-Ogu-078899	Oryza glumaepatula	27.34	1.00e-17	84.00
IUUC-Oin-079167	Oryza indica	27.34	1.00e-17	84.00
IUUC-Olo-080451	Oryza longistaminata	27.84	1.00e-17	83.60
IUUC-Ome-081836	Oryza meridionalis	27.70	1.00e-17	84.00
IUUC-Oni-083019	Oryza nivara	27.34	1.00e-17	84.00
IUUC-Opu-083122	Oryza punctata	27.90	7.00e-18	84.70
IUUC-Oru-084900	Oryza rufipogon	27.34	1.00e-17	84.00
IUUC-Osa-086054	Oryza sativa	27.34	1.00e-17	84.00
IUUC-Ola-087077	Oryzias latipes	68.63	0.00e+00	859.00
IUUC-Olu-087601	Ostreococcus lucimarinus	26.27	7.00e-06	45.10
IUUC-Oga-088049	Otolemur garnettii	83.50	0.00e+00	1043.00
IUUC-Oar-089678	Ovis aries	97.36	0.00e+00	1247.00
IUUC-Ptr-091380	Pan troglodytes	97.34	0.00e+00	1145.00
IUUC-Pan-092821	Papio anubis	97.18	0.00e+00	1239.00
IUUC-Psi-093074	Pelodiscus sinensis	92.74	0.00e+00	1180.00
IUUC-Pma-094102	Petromyzon marinus	69.50	0.00e+00	906.00
IUUC-Pno-094987	Phaeosphaeria nodorum	34.21	1.00e-93	338.00
IUUC-Ppa-095368	Physcomitrella patens	28.27	2.00e-18	86.70
IUUC-Pfo-097245	Poecilia formosa	80.79	0.00e+00	1000.00
IUUC-Pab-098763	Pongo abelii	98.51	0.00e+00	1254.00
IUUC-Pop-099355	Populus trichocarpa	30.26	1.00e-14	73.60
IUUC-Ppe-101990	Prunus persica	28.16	5.00e-18	85.50
IUUC-Pva-102308	Pteropus vampyrus	89.33	0.00e+00	969.00
IUUC-Pgr-103553	Puccinia graminis	32.67	5.00e-81	295.00
IUUC-Pte-104100	Pyrenophora teres	32.56	8.00e-90	324.00
IUUC-Pyt-104482	Pyrenophora triticirepentis	33.50	3.00e-91	329.00
IUUC-Rno-105582	Rattus norvegicus	96.88	0.00e+00	1216.00
IUUC-Sce-106145	Saccharomyces cerevisiae	33.73	3.00e-90	325.00
IUUC-Sha-106647	Sarcophilus harrisii	96.27	0.00e+00	1200.00
IUUC-Sja-107972	Schizosaccharomyces japonicus	35.53	9.00e-86	310.00
IUUC-Spo-108281	Schizosaccharomyces pombe	34.61	6.00e-92	331.00
IUUC-Ssl-108617	Sclerotinia sclerotiorum	37.61	5.00e-91	328.00
IUUC-Smo-108933	Selaginella moellendorffii	30.09	4.00e-19	89.00
IUUC-Sit-110083	Setaria italica	27.14	4.00e-16	79.30
IUUC-Sly-111645	Solanum lycopersicum	26.00	2.00e-16	80.50
IUUC-Stu-112422	Solanum tuberosum	26.00	1.00e-16	80.90
IUUC-Sbi-113987	Sorghum bicolor	30.07	6.00e-17	81.60
IUUC-Sre-115095	Sporisorium reilianum	37.77	2.00e-80	293.00
IUUC-Ssc-116141	Sus scrofa	95.73	0.00e+00	1100.00
IUUC-Tgu-117492	Taeniopygia guttata	90.87	0.00e+00	863.00
IUUC-Tru-118463	Takifugu rubripes	77.80	0.00e+00	979.00
IUUC-Tsy-118993	Tarsius syrichta	88.91	0.00e+00	1010.00
IUUC-Tni-119896	Tetraodon nigroviridis	79.64	0.00e+00	982.00
IUUC-Tca-121169	Theobroma cacao	28.12	9.00e-20	90.90
IUUC-Tre-122046	Trichoderma reesei	32.84	7.00e-91	328.00
IUUC-Tvi-122415	Trichoderma virens	33.06	1.00e-91	330.00
IUUC-Tae-123514	Triticum aestivum	27.68	5.00e-15	75.10
IUUC-Tur-126703	Triticum urartu	45.45	2.80e-01	29.30
IUUC-Tme-127123	Tuber melanosporum	36.43	5.00e-103	368.00
IUUC-Tbe-127629	Tupaia belangeri	91.12	1.00e-157	550.00
IUUC-Ttr-128476	Tursiops truncatus	86.96	0.00e+00	974.00
IUUC-Uma-129492	Ustilago maydis	34.99	6.00e-84	305.00
IUUC-Vda-129702	Verticillium dahliae	36.34	4.00e-89	322.00
IUUC-Vvi-131090	Vitis vinifera	29.90	6.00e-14	71.60
IUUC-Xtr-131786	Xenopus tropicalis	86.13	0.00e+00	1077.00
IUUC-Xma-133997	Xiphophorus maculatus	78.25	0.00e+00	997.00
IUUC-Yli-134537	Yarrowia lipolytica	35.46	1.00e-89	323.00
IUUC-Zma-134847	Zea mays	29.37	4.00e-18	85.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence