iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071834

Ensembl Protein ID

ENSONIP00000012282.1

UniProt Accession

I3JTT7; I3JTT7_ORENI

Genbank Protein ID

ENSONIP00000012282

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01012772

Gene Name

USP15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000009776.1	ENSONIT00000012291.1	ENSONIP00000012282.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.50e-118	395.5	291	938
ULD/UDP/UBQ/UBQ_Other	1.60e-07	31.5	147	217

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS++QcLsn+p+l+e++l+ k++ +lne+np ++kge+++++++l+++lw++k ++v+pr ++++++++a++fsgy+
   Q: 291  CGLSNLGNTCFMNSAVQCLSNTPPLTEYFLKdKYTDELNEDNPLGMKGEIARAYAELIKQLWSGKYSYVTPRPFKTQVGRFAPQFSGYQ 379
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD++E+laflld+l+e+l++ ++kp+ ++++++   ++d+     a+e++ k+n+s+i+d+F+g +ks+++c+ c +vs++++pf++l
   Q: 380  QQDSHELLAFLLDGLHEDLNRIRKKPYIQLKDAN--GRPDKvvaeeAWENHIKRNDSIIVDIFHGLFKSTLVCPVCSKVSVTFDPFCYL 466
           ****************************998888..5555556777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+k+e+ +e                                                                            
   Q: 467  TLPLPMKKERTLEvylvrldplakptqykltvpkvgyisdlctslsnlsgvpaekmivtdiynhrfhrifatnenlssimerddiyvfe 555
           *********9999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 556  vavnrvedtdhvvipvhlrekykqsgynhtstplfgqpfliavprtlsedklynmllqrlcrfvrssveeeeddceetqpskqhtvngn 644
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 645  atnglleegspsemetdeqddessqdqelpsendnsqsedsvggdnelengvvgpqnstkgqqtsghnrkrlftfqfnnmgktdfslik 733
           ***************************************************************************************** PP
   S: 186  ..........................................................slqdcLesftkeeelegenkyycekckkkqe 216
                                                                     +l+dc+e ft++e+l  e+ +yc++ck++q+
   Q: 734  edtrqirfdeghlrlsdrsylsldwepeikkkyfdetvvedfdkhesmeykpqkkaffKLKDCIELFTTKEKLGAEDPWYCPNCKQHQQ 822
           ***************************************************************************************** PP
   S: 217  aekklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekg 304
           a+kkl+l++lP+vL++hLkRfs+s+  ++r k+++ v+fpl+ Ld+s+f+++p+ +   +++Y+Liav +H+G++++GHY+ y+kn+++
   Q: 823  ATKKLDLWSLPPVLVVHLKRFSYSR--YMRDKLDSLVDFPLRdLDMSEFLINPNAG---PCRYDLIAVSNHYGGMGGGHYTGYAKNKDD 906
           *********************9977..6999*********************9988...8**************************655 PP
   S: 305  k.WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           + W++fdDs+V++ +e+++++   + aYvlfY+r+
   Q: 907  GkWYNFDDSSVSPASEDQIVS---KAAYVLFYQRQ 938
           55*******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           + t +++++dt+  + ++++k+++ip + + rL+++      ++L ++d t++d gl++g+++++++k+++
   Q: 147  VITKRFSKADTIDMIEKEMRKLFSIPdEKETRLWNRymsntFEPLnKPDSTIQDAGLYQGQVLVIEQKNED 217
           5567799*******************999*****776664444469*********************9986 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAEGGAADLD TQRGEVATLL KTQLRKGDTW YLVDSHWFKQ WKKYVGFDSW DKYQMGDQNV 60
YPGPVDNSGL LKDGDVLAIK EHLIDELDYI LVPTEGWNKL VSWYGLTEGQ EPIARKVVEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGGAATGT CTAAGGAAAG ATGGCGGAAG GAGGAGCGGC TGATCTGGAT ACCCAAAGAG 60
GAGAGGTCGC GACACTGTTG AAAACACAAC TAAGAAAGGG AGACACTTGG TAAGAATTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001852	Ailuropoda melanoleuca	80.55	0.00e+00	1514.00
IUUC-Apl-003249	Anas platyrhynchos	80.09	0.00e+00	1417.00
IUUC-Aca-004261	Anolis carolinensis	79.43	0.00e+00	1430.00
IUUC-Aly-005644	Arabidopsis lyrata	35.44	4.00e-137	482.00
IUUC-Ath-006782	Arabidopsis thaliana	35.44	1.00e-139	490.00
IUUC-Ame-010757	Astyanax mexicanus	91.79	0.00e+00	1438.00
IUUC-Bta-013128	Bos taurus	78.63	0.00e+00	1494.00
IUUC-Bol-015244	Brassica oleracea	36.12	5.00e-149	521.00
IUUC-Bra-016885	Brassica rapa	36.09	4.00e-148	519.00
IUUC-Cel-018203	Caenorhabditis elegans	58.71	2.00e-70	260.00
IUUC-Cja-019222	Callithrix jacchus	80.42	0.00e+00	1517.00
IUUC-Cfa-020035	Canis familiaris	80.55	0.00e+00	1514.00
IUUC-Cpo-022071	Cavia porcellus	80.47	0.00e+00	1472.00
IUUC-Csa-023882	Chlorocebus sabaeus	80.42	0.00e+00	1516.00
IUUC-Cin-025292	Ciona intestinalis	43.97	0.00e+00	727.00
IUUC-Cne-026852	Cryptococcus neoformans	40.76	1.00e-73	272.00
IUUC-Cme-027338	Cyanidioschyzon merolae	54.46	2.00e-66	248.00
IUUC-Dno-029025	Dasypus novemcinctus	76.40	0.00e+00	1423.00
IUUC-Dor-030956	Dipodomys ordii	73.48	0.00e+00	1283.00
IUUC-Dse-031432	Dothistroma septosporum	41.30	4.00e-59	224.00
IUUC-Eca-034340	Equus caballus	80.43	0.00e+00	1462.00
IUUC-Eeu-034488	Erinaceus europaeus	71.08	0.00e+00	1007.00
IUUC-Fca-035552	Felis catus	78.42	0.00e+00	1491.00
IUUC-Fal-036618	Ficedula albicollis	80.09	0.00e+00	1415.00
IUUC-Fox-037986	Fusarium oxysporum	30.84	4.00e-69	257.00
IUUC-Fso-038291	Fusarium solani	30.60	1.00e-70	262.00
IUUC-Gmo-038680	Gadus morhua	71.27	0.00e+00	897.00
IUUC-Gga-041146	Gallus gallus	79.66	0.00e+00	1461.00
IUUC-Gac-041679	Gasterosteus aculeatus	94.53	0.00e+00	1716.00
IUUC-Gma-043077	Glycine max	37.17	5.00e-147	515.00
IUUC-Ggo-045002	Gorilla gorilla	80.24	0.00e+00	1457.00
IUUC-Hsa-046052	Homo sapiens	80.53	0.00e+00	1518.00
IUUC-Itr-048306	Ictidomys tridecemlineatus	78.68	0.00e+00	1494.00
IUUC-Kpa-049332	Komagataella pastoris	32.14	9.00e-72	265.00
IUUC-Lch-050107	Latimeria chalumnae	80.84	0.00e+00	1572.00
IUUC-Loc-052105	Lepisosteus oculatus	86.93	0.00e+00	1565.00
IUUC-Lma-052981	Leptosphaeria maculans	32.82	3.00e-67	251.00
IUUC-Laf-053645	Loxodonta africana	80.63	0.00e+00	1516.00
IUUC-Mcc-055586	Macaca mulatta	80.53	0.00e+00	1518.00
IUUC-Mor-056985	Magnaporthe oryzae	40.93	6.00e-61	230.00
IUUC-Mtr-058138	Medicago truncatula	37.20	2.00e-150	526.00
IUUC-Mga-060162	Meleagris gallopavo	79.87	0.00e+00	1465.00
IUUC-Mmr-061105	Microcebus murinus	80.32	0.00e+00	1514.00
IUUC-Mdo-062107	Monodelphis domestica	80.00	0.00e+00	1504.00
IUUC-Mmu-063662	Mus musculus	80.11	0.00e+00	1508.00
IUUC-Mac-064956	Musa acuminata	40.82	1.00e-114	407.00
IUUC-Mpu-065868	Mustela putorius furo	78.97	0.00e+00	1505.00
IUUC-Mlu-068000	Myotis lucifugus	75.97	0.00e+00	1372.00
IUUC-Nle-069874	Nomascus leucogenys	80.42	0.00e+00	1515.00
IUUC-Opr-071212	Ochotona princeps	76.42	0.00e+00	1415.00
IUUC-Ocu-074573	Oryctolagus cuniculus	80.53	0.00e+00	1515.00
IUUC-Oba-075553	Oryza barthii	41.29	3.00e-126	446.00
IUUC-Obr-076902	Oryza brachyantha	36.65	1.00e-142	500.00
IUUC-Ogl-077583	Oryza glaberrima	41.29	3.00e-126	446.00
IUUC-Ogu-077990	Oryza glumaepatula	40.72	9.00e-121	428.00
IUUC-Oin-079300	Oryza indica	41.44	5.00e-127	449.00
IUUC-Olo-080387	Oryza longistaminata	40.25	6.00e-118	419.00
IUUC-Ome-081963	Oryza meridionalis	40.03	8.00e-119	421.00
IUUC-Oni-082303	Oryza nivara	41.03	2.00e-121	431.00
IUUC-Opu-083770	Oryza punctata	39.43	2.00e-122	433.00
IUUC-Oru-085141	Oryza rufipogon	41.12	3.00e-123	436.00
IUUC-Osa-085641	Oryza sativa	41.44	5.00e-127	449.00
IUUC-Olu-087717	Ostreococcus lucimarinus	39.06	3.00e-118	419.00
IUUC-Oga-089022	Otolemur garnettii	78.95	0.00e+00	1499.00
IUUC-Oar-089767	Ovis aries	80.32	0.00e+00	1510.00
IUUC-Ptr-091319	Pan troglodytes	78.74	0.00e+00	1501.00
IUUC-Pan-091968	Papio anubis	80.42	0.00e+00	1516.00
IUUC-Psi-093849	Pelodiscus sinensis	79.78	0.00e+00	1404.00
IUUC-Pma-094533	Petromyzon marinus	59.71	0.00e+00	1092.00
IUUC-Pno-094890	Phaeosphaeria nodorum	32.04	1.00e-59	225.00
IUUC-Pfo-097110	Poecilia formosa	94.95	0.00e+00	1740.00
IUUC-Pab-098664	Pongo abelii	80.42	0.00e+00	1516.00
IUUC-Pop-099801	Populus trichocarpa	36.57	8.00e-152	531.00
IUUC-Pca-100359	Procavia capensis	64.33	0.00e+00	1025.00
IUUC-Ppe-101587	Prunus persica	37.85	4.00e-149	522.00
IUUC-Pva-102394	Pteropus vampyrus	78.63	0.00e+00	1467.00
IUUC-Pte-104102	Pyrenophora teres	36.31	7.00e-57	217.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	39.25	1.00e-56	216.00
IUUC-Rno-105383	Rattus norvegicus	78.74	0.00e+00	1497.00
IUUC-Sha-107393	Sarcophilus harrisii	79.79	0.00e+00	1504.00
IUUC-Ssl-108461	Sclerotinia sclerotiorum	28.57	5.00e-11	63.50
IUUC-Smo-109356	Selaginella moellendorffii	48.65	2.00e-80	293.00
IUUC-Sit-109901	Setaria italica	40.98	1.00e-123	437.00
IUUC-Sly-111726	Solanum lycopersicum	39.78	6.00e-99	355.00
IUUC-Sar-113498	Sorex araneus	80.21	0.00e+00	1509.00
IUUC-Sbi-114874	Sorghum bicolor	35.60	1.00e-135	477.00
IUUC-Sre-115130	Sporisorium reilianum	32.24	4.00e-88	320.00
IUUC-Ssc-115285	Sus scrofa	80.34	0.00e+00	1510.00
IUUC-Tgu-116529	Taeniopygia guttata	80.08	0.00e+00	1469.00
IUUC-Tru-118298	Takifugu rubripes	90.53	0.00e+00	1748.00
IUUC-Tsy-119117	Tarsius syrichta	71.38	0.00e+00	868.00
IUUC-Tni-120093	Tetraodon nigroviridis	88.28	0.00e+00	1667.00
IUUC-Tca-121670	Theobroma cacao	39.66	1.00e-111	397.00
IUUC-Tur-126392	Triticum urartu	34.37	4.00e-88	319.00
IUUC-Tbe-127672	Tupaia belangeri	73.26	0.00e+00	1009.00
IUUC-Uma-129498	Ustilago maydis	33.48	3.00e-81	297.00
IUUC-Vda-129781	Verticillium dahliae	38.36	2.00e-68	254.00
IUUC-Vpa-130469	Vicugna pacos	79.89	0.00e+00	1441.00
IUUC-Vvi-131454	Vitis vinifera	36.32	5.00e-123	435.00
IUUC-Xtr-132729	Xenopus tropicalis	74.32	0.00e+00	1399.00
IUUC-Xma-133550	Xiphophorus maculatus	94.74	0.00e+00	1731.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence