iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117232

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01002151

Gene Name

TRAF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000010139.1	ENSTGUT00000010572.1	ENSTGUP00000010462.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	5.50e-07	29.4	66	127

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrli 65
           + + CpI l   r+ v +p+G+ + + +I k +++ g++cPv+++ l e++l P ++ +r i
   Q: 66   SKYECPICLMALREAVQTPCGHRFCKGCIVKSIRDAGHKCPVDNEILLENQLFPDNFAKREI 127
           5689*****************************999999*****************999977 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MSLLHSDSSC GGRDAESGCC AAMASACSAA AKEESSSVGS AVGTAPGSFG EETQGYDVEF 60
DPPLESKYEC PICLMALREA VQTPCGHRFC KGCIVKSIRD AGHKCPVDNE ILLENQLFPD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCTTGC TGCACAGTGA CAGCAGCTGT GGAGGCCGAG ATGCGGAGAG CGGCTGCTGC 60
GCAGCCATGG CCAGCGCCTG CAGCGCCGCA GCCAAGGAGG AGAGCTCCAG CGTGGGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027139--TRAF6
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:0005811--C:lipid particle
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0043234--C:protein complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0009887--P:animal organ morphogenesis
GO:0019886--P:antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0045453--P:bone resorption
GO:0048468--P:cell development
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:0043011--P:myeloid dendritic cell differentiation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0001843--P:neural tube closure
GO:0001503--P:ossification
GO:0030316--P:osteoclast differentiation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045084--P:positive regulation of interleukin-12 biosynthetic process
GO:0032743--P:positive regulation of interleukin-2 production
GO:0045410--P:positive regulation of interleukin-6 biosynthetic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0031666--P:positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0045672--P:positive regulation of osteoclast differentiation
GO:0002726--P:positive regulation of T cell cytokine production
GO:0042102--P:positive regulation of T cell proliferation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000679--P:positive regulation of transcription regulatory region DNA binding
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042981--P:regulation of apoptotic process
GO:0051023--P:regulation of immunoglobulin secretion
GO:0050852--P:T cell receptor signaling pathway
GO:0042088--P:T-helper 1 type immune response

KEGG

tgu:100229606

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001262	Ailuropoda melanoleuca	74.82	0.00e+00	802.00
IUUC-Apl-004062	Anas platyrhynchos	91.09	0.00e+00	1029.00
IUUC-Aca-004636	Anolis carolinensis	77.55	0.00e+00	845.00
IUUC-Ame-011682	Astyanax mexicanus	55.43	5.00e-163	566.00
IUUC-Bta-012692	Bos taurus	73.63	0.00e+00	807.00
IUUC-Bci-013998	Botrytis cinerea	24.07	9.00e-14	71.20
IUUC-Bol-016391	Brassica oleracea	28.03	1.00e-07	51.20
IUUC-Cja-019426	Callithrix jacchus	72.29	0.00e+00	790.00
IUUC-Cfa-020948	Canis familiaris	74.24	0.00e+00	723.00
IUUC-Cpo-021378	Cavia porcellus	73.90	0.00e+00	801.00
IUUC-Csa-024045	Chlorocebus sabaeus	72.66	0.00e+00	805.00
IUUC-Cho-024973	Choloepus hoffmanni	59.75	9.00e-77	280.00
IUUC-Csv-026300	Ciona savignyi	40.52	5.00e-48	183.00
IUUC-Dre-027557	Danio rerio	60.36	5.00e-178	616.00
IUUC-Dno-030032	Dasypus novemcinctus	70.00	2.00e-119	421.00
IUUC-Dor-030790	Dipodomys ordii	73.21	0.00e+00	797.00
IUUC-Dme-031921	Drosophila melanogaster	27.59	5.00e-41	161.00
IUUC-Ete-032952	Echinops telfairi	71.72	2.00e-148	518.00
IUUC-Eca-033924	Equus caballus	69.84	0.00e+00	719.00
IUUC-Eeu-034734	Erinaceus europaeus	65.75	0.00e+00	688.00
IUUC-Fca-036222	Felis catus	67.14	0.00e+00	704.00
IUUC-Fal-036834	Ficedula albicollis	97.24	0.00e+00	969.00
IUUC-Fox-037935	Fusarium oxysporum	30.05	6.00e-22	98.60
IUUC-Gmo-039061	Gadus morhua	61.13	4.00e-88	318.00
IUUC-Ggr-040084	Gaeumannomyces graminis	27.54	1.00e-13	70.90
IUUC-Gga-040599	Gallus gallus	92.83	0.00e+00	1043.00
IUUC-Gac-041977	Gasterosteus aculeatus	56.63	6.00e-174	603.00
IUUC-Ggo-044508	Gorilla gorilla	68.67	0.00e+00	733.00
IUUC-Hsa-046349	Homo sapiens	72.48	0.00e+00	807.00
IUUC-Itr-047966	Ictidomys tridecemlineatus	72.21	0.00e+00	800.00
IUUC-Lch-049821	Latimeria chalumnae	70.48	0.00e+00	780.00
IUUC-Lpe-051100	Leersia perrieri	35.00	4.00e-06	45.10
IUUC-Loc-051995	Lepisosteus oculatus	61.60	0.00e+00	655.00
IUUC-Laf-054115	Loxodonta africana	72.29	0.00e+00	798.00
IUUC-Mcc-055298	Macaca mulatta	72.29	0.00e+00	800.00
IUUC-Mor-057263	Magnaporthe oryzae	30.90	9.00e-21	94.70
IUUC-Mpo-057517	Magnaporthe poae	29.33	9.00e-16	78.20
IUUC-Mga-059340	Meleagris gallopavo	93.20	0.00e+00	1041.00
IUUC-Mvi-060553	Microbotryum violaceum	28.10	4.00e-18	85.50
IUUC-Mmr-061063	Microcebus murinus	73.94	0.00e+00	808.00
IUUC-Mdo-062075	Monodelphis domestica	72.11	0.00e+00	792.00
IUUC-Mmu-063780	Mus musculus	74.25	0.00e+00	776.00
IUUC-Mpu-065748	Mustela putorius furo	74.86	0.00e+00	807.00
IUUC-Mlu-067888	Myotis lucifugus	73.21	0.00e+00	799.00
IUUC-Ncr-068632	Neurospora crassa	25.23	3.00e-15	76.30
IUUC-Nle-069234	Nomascus leucogenys	72.11	0.00e+00	800.00
IUUC-Opr-070393	Ochotona princeps	80.28	4.00e-104	370.00
IUUC-Ont-072459	Oreochromis niloticus	58.35	2.00e-179	622.00
IUUC-Oan-073578	Ornithorhynchus anatinus	76.57	0.00e+00	856.00
IUUC-Ocu-074201	Oryctolagus cuniculus	73.22	0.00e+00	799.00
IUUC-Oni-083040	Oryza nivara	33.33	2.00e-06	46.20
IUUC-Ola-087319	Oryzias latipes	49.64	7.00e-153	533.00
IUUC-Oga-087936	Otolemur garnettii	72.11	0.00e+00	789.00
IUUC-Oar-089379	Ovis aries	73.44	0.00e+00	813.00
IUUC-Ptr-090758	Pan troglodytes	72.48	0.00e+00	803.00
IUUC-Pan-092590	Papio anubis	72.48	0.00e+00	801.00
IUUC-Psi-093948	Pelodiscus sinensis	82.45	0.00e+00	927.00
IUUC-Pma-094434	Petromyzon marinus	46.24	2.00e-129	455.00
IUUC-Pno-094854	Phaeosphaeria nodorum	26.43	3.00e-11	62.80
IUUC-Pfo-096912	Poecilia formosa	57.81	2.00e-174	605.00
IUUC-Pab-097651	Pongo abelii	72.48	0.00e+00	804.00
IUUC-Pca-100958	Procavia capensis	69.70	3.00e-169	587.00
IUUC-Pva-103247	Pteropus vampyrus	73.41	2.00e-101	362.00
IUUC-Pte-104279	Pyrenophora teres	26.64	1.00e-13	71.60
IUUC-Pyt-104429	Pyrenophora triticirepentis	26.94	1.00e-12	67.80
IUUC-Rno-104994	Rattus norvegicus	72.96	0.00e+00	785.00
IUUC-Sha-106494	Sarcophilus harrisii	73.94	0.00e+00	813.00
IUUC-Ssl-108580	Sclerotinia sclerotiorum	24.07	2.00e-13	70.50
IUUC-Sar-113375	Sorex araneus	74.18	0.00e+00	805.00
IUUC-Sre-115218	Sporisorium reilianum	28.02	4.00e-18	86.30
IUUC-Ssc-115417	Sus scrofa	74.13	0.00e+00	815.00
IUUC-Tru-118321	Takifugu rubripes	57.74	6.00e-176	610.00
IUUC-Tni-120475	Tetraodon nigroviridis	57.14	1.00e-171	595.00
IUUC-Tur-126067	Triticum urartu	32.46	2.00e-08	52.40
IUUC-Tbe-127719	Tupaia belangeri	62.71	0.00e+00	659.00
IUUC-Ttr-129264	Tursiops truncatus	73.52	1.00e-101	362.00
IUUC-Uma-129620	Ustilago maydis	23.01	3.00e-16	80.10
IUUC-Vpa-130244	Vicugna pacos	74.31	5.00e-104	371.00
IUUC-Xtr-131948	Xenopus tropicalis	69.18	0.00e+00	762.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence