iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072446

Ensembl Protein ID

ENSONIP00000016230.1

UniProt Accession

I3K535; I3K535_ORENI

Genbank Protein ID

ENSONIP00000016230

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AERX01024651

Gene Name

ing4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000012899.1	ENSONIT00000016245.1	ENSONIP00000016230.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.10e-09	38.7	197	244

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 197  TYC-LCHQVSYGE--MIGCDNtdCSiEWFHFACVGLT---TKPRGK-WYCPRCSQ 244
           69*.*******99..*****999999***********...899996.******86 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MAAGMYLEHY LDSIENLPFE LQRNFNLMRD LDQRTEDLKG QIDSLAKEYT ANARTLSSEQ 60
KLSILRQIQQ SYSKCKEFGD DKVQLAMQTY EMVDKHIRRL DTDLARFEAD LKEKQIESTD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG GAATGTATTT GGAGCATTAT TTGGACAGTA AGTGAATTTG TACGTGCTTC 60
TGATGCATTG AAAAACATCC TTAGTCGTTT TATAGTTTAA TTTCTTTGTG TAGTGTATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001338	Ailuropoda melanoleuca	81.60	2.00e-106	378.00
IUUC-Apl-004097	Anas platyrhynchos	79.52	5.00e-107	380.00
IUUC-Aca-004593	Anolis carolinensis	82.80	7.00e-113	399.00
IUUC-Ath-006578	Arabidopsis thaliana	35.27	7.00e-36	144.00
IUUC-Ame-011133	Astyanax mexicanus	89.60	1.00e-134	471.00
IUUC-Bta-012699	Bos taurus	81.60	1.00e-107	382.00
IUUC-Bdi-014504	Brachypodium distachyon	35.91	3.00e-40	158.00
IUUC-Bol-015751	Brassica oleracea	35.16	2.00e-36	146.00
IUUC-Bra-017027	Brassica rapa	30.56	6.00e-32	130.00
IUUC-Cel-018700	Caenorhabditis elegans	45.45	2.00e-07	52.00
IUUC-Cja-019988	Callithrix jacchus	81.60	7.00e-102	363.00
IUUC-Cfa-021282	Canis familiaris	81.20	2.00e-101	361.00
IUUC-Cpo-022011	Cavia porcellus	82.00	5.00e-110	390.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	31.68	2.00e-28	119.00
IUUC-Csa-023203	Chlorocebus sabaeus	81.60	7.00e-102	363.00
IUUC-Cin-025479	Ciona intestinalis	60.92	2.00e-78	285.00
IUUC-Csv-026288	Ciona savignyi	53.11	3.00e-75	275.00
IUUC-Dre-028264	Danio rerio	88.40	7.00e-132	462.00
IUUC-Dno-029766	Dasypus novemcinctus	78.31	1.00e-94	339.00
IUUC-Dor-031136	Dipodomys ordii	71.31	6.00e-83	300.00
IUUC-Eca-033565	Equus caballus	81.60	3.00e-109	387.00
IUUC-Eeu-034948	Erinaceus europaeus	68.95	3.00e-88	318.00
IUUC-Fca-036368	Felis catus	81.60	7.00e-102	363.00
IUUC-Fal-037120	Ficedula albicollis	79.12	9.00e-106	375.00
IUUC-Gmo-038982	Gadus morhua	97.20	1.00e-145	508.00
IUUC-Gga-040771	Gallus gallus	82.80	7.00e-113	399.00
IUUC-Gac-042184	Gasterosteus aculeatus	97.55	4.00e-144	503.00
IUUC-Gma-044339	Glycine max	30.16	6.00e-34	137.00
IUUC-Ggo-045559	Gorilla gorilla	81.60	7.00e-102	363.00
IUUC-Hsa-046852	Homo sapiens	81.60	7.00e-102	363.00
IUUC-Hvu-047046	Hordeum vulgare	34.13	4.00e-38	151.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	82.00	8.00e-110	389.00
IUUC-Lpe-050822	Leersia perrieri	35.11	2.00e-38	152.00
IUUC-Loc-052334	Lepisosteus oculatus	71.54	2.00e-102	365.00
IUUC-Laf-054057	Loxodonta africana	81.60	7.00e-102	363.00
IUUC-Mcc-055212	Macaca mulatta	77.69	3.00e-100	357.00
IUUC-Meu-056511	Macropus eugenii	81.01	8.00e-101	359.00
IUUC-Mtr-058089	Medicago truncatula	32.27	4.00e-35	141.00
IUUC-Mga-059967	Meleagris gallopavo	80.24	3.00e-106	377.00
IUUC-Mmr-060843	Microcebus murinus	80.40	7.00e-107	379.00
IUUC-Mdo-062357	Monodelphis domestica	80.80	1.00e-108	385.00
IUUC-Mmu-064093	Mus musculus	82.00	5.00e-110	390.00
IUUC-Mac-064625	Musa acuminata	35.14	9.00e-38	150.00
IUUC-Mpu-066923	Mustela putorius furo	70.80	1.00e-79	288.00
IUUC-Mlu-067754	Myotis lucifugus	78.17	4.00e-108	384.00
IUUC-Nle-069062	Nomascus leucogenys	81.60	7.00e-102	363.00
IUUC-Opr-070207	Ochotona princeps	75.53	3.00e-93	334.00
IUUC-Ocu-074235	Oryctolagus cuniculus	81.60	7.00e-102	363.00
IUUC-Obr-076266	Oryza brachyantha	35.11	3.00e-38	151.00
IUUC-Ogl-077118	Oryza glaberrima	35.14	1.00e-37	149.00
IUUC-Oin-079049	Oryza indica	35.79	6.00e-39	154.00
IUUC-Ome-081291	Oryza meridionalis	34.36	2.00e-38	152.00
IUUC-Oni-082218	Oryza nivara	35.79	6.00e-39	154.00
IUUC-Opu-084171	Oryza punctata	36.05	3.00e-37	149.00
IUUC-Osa-085563	Oryza sativa	34.36	2.00e-38	152.00
IUUC-Ola-086429	Oryzias latipes	94.78	2.00e-139	488.00
IUUC-Oga-089123	Otolemur garnettii	81.60	7.00e-102	363.00
IUUC-Oar-089524	Ovis aries	81.60	1.00e-107	382.00
IUUC-Ptr-090908	Pan troglodytes	81.60	7.00e-102	363.00
IUUC-Pan-092837	Papio anubis	81.60	2.00e-106	377.00
IUUC-Psi-093828	Pelodiscus sinensis	81.62	5.00e-102	363.00
IUUC-Ppa-096009	Physcomitrella patens	36.68	6.00e-38	150.00
IUUC-Pfo-096617	Poecilia formosa	95.98	2.00e-144	504.00
IUUC-Pab-097978	Pongo abelii	80.17	5.00e-91	327.00
IUUC-Pop-099415	Populus trichocarpa	68.25	4.00e-26	111.00
IUUC-Pca-100475	Procavia capensis	55.02	8.00e-75	273.00
IUUC-Ppe-101441	Prunus persica	33.59	7.00e-38	150.00
IUUC-Pva-102325	Pteropus vampyrus	81.60	3.00e-109	387.00
IUUC-Rno-105178	Rattus norvegicus	81.20	3.00e-116	410.00
IUUC-Sha-106773	Sarcophilus harrisii	80.80	1.00e-108	385.00
IUUC-Smo-109441	Selaginella moellendorffii	33.85	2.00e-40	158.00
IUUC-Sit-109827	Setaria italica	36.68	2.00e-36	145.00
IUUC-Sbi-114826	Sorghum bicolor	36.68	3.00e-37	148.00
IUUC-Sre-115124	Sporisorium reilianum	59.32	6.00e-22	99.40
IUUC-Ssc-115797	Sus scrofa	76.83	5.00e-91	327.00
IUUC-Tgu-117270	Taeniopygia guttata	82.80	7.00e-113	399.00
IUUC-Tru-118253	Takifugu rubripes	97.21	1.00e-145	508.00
IUUC-Tca-121597	Theobroma cacao	34.92	1.00e-33	136.00
IUUC-Tae-123043	Triticum aestivum	34.48	3.00e-38	151.00
IUUC-Tbe-127558	Tupaia belangeri	81.60	2.00e-106	378.00
IUUC-Ttr-128300	Tursiops truncatus	78.38	2.00e-50	192.00
IUUC-Uma-129581	Ustilago maydis	59.32	7.00e-22	99.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence