iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/U-box	U-box	14657406; 18552232

Classification

Family	E-value	Score	Start	End
E3 activity/RING/U-box	4.20e-19	69.3	33	107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedl.vPnltlrrliqawceenss 74
           +p eflCpIs+ +M+dPvv++sG+t++r +++ + + +   +   ++++l + +  +Pnl ++++i+ wc++ ++
   Q: 33   PPVEFLCPISKSVMSDPVVVSSGQTFERVCVQVCRDLNFIpKLNDDEESLPDFSNiIPNLNMKSTIDTWCDTVGV 107
           799********************************99988788999999*888877***************9875 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Functions as an E3 ubiquitin ligase.

Protein Sequence
(Fasta)

MGKNGRLRWN PFSHRSSSST SSSSRQQQQE QQPPVEFLCP ISKSVMSDPV VVSSGQTFER 60
VCVQVCRDLN FIPKLNDDEE SLPDFSNIIP NLNMKSTIDT WCDTVGVSRP QPPDYSTVER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAGCCAAA AAAAAAAAGT CAGTAGGCCA CAAAGTCCTT CAGTTCAGGA GGAAGAAGAC 60
GACTCTCCTC TCTTCTCATC TTTCTTCTTC TTCTCAGAAA ATCACGAAAG ATGAATTCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000225--Armadillo
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF00514--Arm
PF04564--U-box

SMART

SM00185--ARM
SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0070696--F:transmembrane receptor protein serine/threonine kinase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0016567--P:protein ubiquitination

KEGG

ath:AT5G65200

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005887	Arabidopsis lyrata	93.53	0.00e+00	969.00
IUUC-Bol-015998	Brassica oleracea	78.80	0.00e+00	743.00
IUUC-Bra-017987	Brassica rapa	77.58	0.00e+00	741.00
IUUC-Gma-043462	Glycine max	58.35	1.00e-161	561.00
IUUC-Mtr-057660	Medicago truncatula	57.58	8.00e-134	469.00
IUUC-Oba-075532	Oryza barthii	42.12	2.00e-35	143.00
IUUC-Opu-083809	Oryza punctata	35.33	2.00e-67	248.00
IUUC-Pop-099467	Populus trichocarpa	60.53	4.00e-156	543.00
IUUC-Ppe-101245	Prunus persica	54.96	7.00e-144	503.00
IUUC-Smo-109005	Selaginella moellendorffii	36.96	1.00e-38	154.00
IUUC-Sit-110079	Setaria italica	42.91	2.00e-41	162.00
IUUC-Sly-111894	Solanum lycopersicum	51.23	9.00e-105	373.00
IUUC-Stu-112202	Solanum tuberosum	49.71	6.00e-114	403.00
IUUC-Sbi-114055	Sorghum bicolor	45.04	8.00e-36	144.00
IUUC-Tca-121713	Theobroma cacao	58.22	2.00e-149	521.00
IUUC-Tae-123319	Triticum aestivum	40.06	1.00e-39	157.00
IUUC-Vvi-131166	Vitis vinifera	53.83	2.00e-131	461.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence