iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ani-009503

Ensembl Protein ID

CADANIAP00003395

UniProt Accession

C8VFS3; C8VFS3_EMENI

Genbank Protein ID

CBF81435.1

Protein Name

Ubiquitin C-terminal hydrolase, putative (AFU_orthologue AFUA_6G12270)

Genbank Nucleotide ID

BN001305

Gene Name

ANIA_10722

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADANIAG00003395	CADANIAT00003395	CADANIAP00003395

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.90e-37	126.7	684	1011

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           ++  +qqD+ E+++ +l q + ++                      +   ++ ++ + ++dlF gq +s i  +  + + s+ee  +d+++
   Q: 684  VEIGAQQDVTEVINNVLFQSQCAIR--------------------GHAVAPDGEQLDQVKDLFYGQARSYILSN--KGKRSKEEWWCDIKI 752
           5555566666666666655555551....................13345556666778888888888777554..444456778888888 PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           +v         ++  +++  +  +++            +++ ae+   ++klP++L ++ +R++f+  +k++ k + ++++++ + l++++
   Q: 753  DVATGPR----DIYAAIDGAFDIQKVSV----------EDSVAEQYAAISKLPPILQIQVQRVQFDPVKKRSFKSTHHLDLKEIIYLDRYM 829
           8887663....78888888887777763..........345599999******************************************** PP
   S: 266  ts.....................peekqke............................................................. 274
            +                           e                                                             
   Q: 830  DTqqpeivnrrkqawewkdtlrkL-----Earraellrqsesdgldtatllksakdiltelsamkqdpdasqdaidvdpqlipelsrleqk 915
           995555555555555555555550.....05555555555555555555555666666666666666666666677777777777777777 PP
   S: 275  ...........................kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevke.eevleetg....staYv 332
                                      +  Y+L+av vH+Gs++ GHY+ y+ + +++ W +++D++Vtev+  +e+ ++++     t+Y 
   Q: 916  aqdemkrleqeikniqamisnqfvdykHLPYRLYAVFVHHGSVEFGHYYIYICDFERNiWRKYNDTYVTEVSDlDEIFKSQDrhnpPTPYF 1006
           77778888999999999999999999999*************************99999************8659999977799******* PP
   S: 333  lfYkr 337
           l+Y +
   Q: 1007 LVYVH 1011
           ***76 PP

Organism

Aspergillus nidulans

Protein Sequence
(Fasta)

MLQKRTDDAF AADPERLEGV PRPEPITVLM NLRTYINNVL RNSQLSKTIQ ANNKRFMTSF 60
GVNGEPCRDL FEYLGFTFRR EGAWDPPRLA AWVQNQVLYK DQQKVFLDDI FHELSALIAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTACAAA AGCGCACGGA TGATGCCTTC GCAGCAGATC CCGAGCGGTT GGAAGGAGTG 60
CCTCGCCCAG AGCCTATAAC GGTCTTGATG AATCTTCGTA CCTATATCAA CAATGTTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR025305--UCH_repeat_domain
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF13446--RPT
PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001340	Ailuropoda melanoleuca	32.82	2.00e-12	67.00
IUUC-Apl-004010	Anas platyrhynchos	34.00	7.00e-12	64.70
IUUC-Aca-004741	Anolis carolinensis	31.78	2.00e-10	60.10
IUUC-Ago-007865	Ashbya gossypii	32.85	2.00e-41	162.00
IUUC-Acl-008164	Aspergillus clavatus	65.48	0.00e+00	1393.00
IUUC-Afl-008717	Aspergillus flavus	65.31	0.00e+00	1393.00
IUUC-Afu-008871	Aspergillus fumigatus	65.81	0.00e+00	1397.00
IUUC-Ang-009577	Aspergillus niger	63.35	0.00e+00	1347.00
IUUC-Aor-009928	Aspergillus oryzae	68.65	0.00e+00	1129.00
IUUC-Ate-010275	Aspergillus terreus	61.88	0.00e+00	1294.00
IUUC-Ame-010624	Astyanax mexicanus	33.02	2.00e-11	62.80
IUUC-Bgr-011993	Blumeria graminis	31.92	2.00e-121	429.00
IUUC-Bta-013166	Bos taurus	33.96	6.00e-12	65.10
IUUC-Bci-013999	Botrytis cinerea	33.15	7.00e-141	493.00
IUUC-Cja-019150	Callithrix jacchus	33.02	2.00e-11	63.20
IUUC-Cfa-020649	Canis familiaris	32.82	2.00e-12	66.60
IUUC-Cpo-021807	Cavia porcellus	33.02	1.00e-11	63.90
IUUC-Csa-023446	Chlorocebus sabaeus	35.85	3.00e-11	62.80
IUUC-Cho-024343	Choloepus hoffmanni	42.03	1.00e-10	60.80
IUUC-Cin-025302	Ciona intestinalis	24.93	2.00e-13	68.90
IUUC-Cgl-026575	Colletotrichum gloeosporioides	23.50	2.00e-45	176.00
IUUC-Cne-026803	Cryptococcus neoformans	23.17	1.00e-11	64.70
IUUC-Cme-027167	Cyanidioschyzon merolae	28.70	3.00e-12	65.90
IUUC-Dno-029495	Dasypus novemcinctus	33.96	5.00e-12	65.10
IUUC-Dor-030955	Dipodomys ordii	37.96	8.00e-11	61.20
IUUC-Dse-031290	Dothistroma septosporum	28.07	2.00e-50	192.00
IUUC-Ete-032828	Echinops telfairi	38.10	3.00e-14	72.40
IUUC-Eca-034300	Equus caballus	35.85	9.00e-12	64.30
IUUC-Fca-035876	Felis catus	32.82	2.00e-12	66.60
IUUC-Fal-036762	Ficedula albicollis	25.81	1.00e-17	82.80
IUUC-Fox-037752	Fusarium oxysporum	27.40	2.00e-30	126.00
IUUC-Fso-038114	Fusarium solani	27.52	3.00e-52	199.00
IUUC-Gmo-039593	Gadus morhua	32.69	8.00e-12	64.70
IUUC-Ggr-039843	Gaeumannomyces graminis	25.05	1.00e-21	97.10
IUUC-Gga-040817	Gallus gallus	34.58	9.00e-12	64.30
IUUC-Gac-042473	Gasterosteus aculeatus	33.02	2.00e-11	63.50
IUUC-Ggo-045384	Gorilla gorilla	35.85	3.00e-11	62.80
IUUC-Hsa-046204	Homo sapiens	33.02	2.00e-11	63.20
IUUC-Itr-048276	Ictidomys tridecemlineatus	36.54	2.00e-11	62.80
IUUC-Kpa-049349	Komagataella pastoris	29.00	1.00e-87	316.00
IUUC-Lch-049692	Latimeria chalumnae	36.70	7.00e-12	64.70
IUUC-Loc-052636	Lepisosteus oculatus	34.86	3.00e-13	69.70
IUUC-Lma-053078	Leptosphaeria maculans	30.67	4.00e-112	397.00
IUUC-Laf-054426	Loxodonta africana	33.96	4.00e-12	65.50
IUUC-Mcc-055473	Macaca mulatta	35.85	3.00e-11	62.80
IUUC-Meu-056416	Macropus eugenii	38.68	7.00e-13	68.20
IUUC-Mor-057281	Magnaporthe oryzae	34.33	1.00e-17	84.30
IUUC-Mpo-057451	Magnaporthe poae	29.60	7.00e-23	101.00
IUUC-Mla-058944	Melampsora laricipopulina	31.40	3.00e-37	149.00
IUUC-Mga-059808	Meleagris gallopavo	34.58	1.00e-11	63.90
IUUC-Mmr-060720	Microcebus murinus	36.79	8.00e-12	64.70
IUUC-Mdo-061955	Monodelphis domestica	38.68	9.00e-13	68.60
IUUC-Mmu-063870	Mus musculus	36.19	7.00e-12	64.70
IUUC-Mpu-066304	Mustela putorius furo	32.82	2.00e-12	67.00
IUUC-Mlu-067139	Myotis lucifugus	25.06	5.00e-18	85.10
IUUC-Nfi-068458	Neosartorya fischeri	66.21	0.00e+00	1431.00
IUUC-Ncr-068739	Neurospora crassa	24.66	2.00e-42	166.00
IUUC-Nle-069075	Nomascus leucogenys	33.02	2.00e-11	63.20
IUUC-Opr-070214	Ochotona princeps	34.78	3.00e-10	59.30
IUUC-Ont-072150	Oreochromis niloticus	33.02	2.00e-11	63.50
IUUC-Oan-073054	Ornithorhynchus anatinus	33.64	1.00e-10	60.80
IUUC-Ocu-074102	Oryctolagus cuniculus	33.96	4.00e-12	65.50
IUUC-Ola-086529	Oryzias latipes	33.02	1.00e-11	64.30
IUUC-Oga-088939	Otolemur garnettii	33.02	2.00e-11	63.50
IUUC-Oar-090266	Ovis aries	33.96	6.00e-12	65.10
IUUC-Ptr-090546	Pan troglodytes	33.02	2.00e-11	63.20
IUUC-Pan-092311	Papio anubis	33.02	2.00e-11	63.90
IUUC-Psi-093422	Pelodiscus sinensis	35.19	4.00e-12	65.90
IUUC-Pno-095093	Phaeosphaeria nodorum	33.94	4.00e-70	258.00
IUUC-Pfo-096726	Poecilia formosa	33.02	1.00e-11	64.30
IUUC-Pab-097608	Pongo abelii	33.02	2.00e-11	63.20
IUUC-Pca-100901	Procavia capensis	35.85	2.00e-11	63.20
IUUC-Pva-103150	Pteropus vampyrus	33.96	3.00e-12	66.20
IUUC-Pgr-103515	Puccinia graminis	37.60	7.00e-36	144.00
IUUC-Ptt-103803	Puccinia triticina	32.46	5.00e-19	87.80
IUUC-Pte-104300	Pyrenophora teres	30.95	1.00e-119	422.00
IUUC-Pyt-104434	Pyrenophora triticirepentis	32.60	1.00e-64	240.00
IUUC-Rno-105735	Rattus norvegicus	36.79	6.00e-12	65.10
IUUC-Sce-106441	Saccharomyces cerevisiae	37.89	5.00e-54	205.00
IUUC-Sha-107489	Sarcophilus harrisii	38.68	9.00e-13	67.80
IUUC-Sja-107936	Schizosaccharomyces japonicus	35.67	1.00e-46	180.00
IUUC-Spo-108381	Schizosaccharomyces pombe	30.40	4.00e-39	155.00
IUUC-Ssl-108532	Sclerotinia sclerotiorum	33.88	3.00e-149	521.00
IUUC-Sar-113097	Sorex araneus	33.96	3.00e-12	65.90
IUUC-Sre-115145	Sporisorium reilianum	26.15	2.00e-46	179.00
IUUC-Ssc-115463	Sus scrofa	35.85	5.00e-12	64.70
IUUC-Tgu-116609	Taeniopygia guttata	34.48	2.00e-11	63.50
IUUC-Tru-118135	Takifugu rubripes	33.02	3.00e-11	62.80
IUUC-Tsy-119471	Tarsius syrichta	40.58	4.00e-10	58.90
IUUC-Tni-120139	Tetraodon nigroviridis	33.06	2.00e-10	60.10
IUUC-Tre-122145	Trichoderma reesei	30.35	2.00e-33	136.00
IUUC-Tvi-122548	Trichoderma virens	29.57	6.00e-32	131.00
IUUC-Tme-126928	Tuber melanosporum	44.38	2.00e-79	289.00
IUUC-Tbe-127549	Tupaia belangeri	33.02	2.00e-11	63.20
IUUC-Ttr-128896	Tursiops truncatus	33.96	4.00e-12	65.90
IUUC-Uma-129338	Ustilago maydis	26.48	1.00e-25	111.00
IUUC-Vda-129742	Verticillium dahliae	26.06	2.00e-28	120.00
IUUC-Vpa-130500	Vicugna pacos	33.96	5.00e-12	65.50
IUUC-Xtr-132436	Xenopus tropicalis	29.92	1.00e-12	67.40
IUUC-Xma-133349	Xiphophorus maculatus	33.02	2.00e-11	63.20
IUUC-Yli-134560	Yarrowia lipolytica	39.26	2.00e-59	223.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence