iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035633

Ensembl Protein ID

ENSFCAP00000004407.2

UniProt Accession

M3W2T5; M3W2T5_FELCA

Genbank Protein ID

ENSFCAP00000004407

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02067963

Gene Name

CTTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000004767.2	ENSFCAT00000004768.2	ENSFCAP00000004407.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.90e-13	47.9	434	483

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 434  VALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--LCKGRYGLFPANYVE 483
           69***********************..9*********..9************97 PP

Organism

Felis catus

Protein Sequence
(Fasta)

SIHKLRENVF QEHQSLKEKE LETGPKASHG YGGKFGVEQD RMDKSAVGHE YQSKLSKHCS 60
QVDSVRGFGG KFGVQVDRVD QSAVGFEYQG KTEKHASQKD YSSGFGGKYG VQADRVDKSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCATACACA AGTTGAGAGA GAATGTTTTT CAAGAACACC AGAGCCTGAA GGAGAAGGAG 60
CTTGAAACGG GACCAAAAGC TTCTCACGGT TACGGCGGGA AGTTCGGCGT GGAGCAGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	94.85	0.00e+00	845.00
IUUC-Apl-003745	Anas platyrhynchos	82.44	0.00e+00	678.00
IUUC-Aca-004438	Anolis carolinensis	78.30	0.00e+00	743.00
IUUC-Bgr-012041	Blumeria graminis	57.89	7.00e-16	79.30
IUUC-Bta-013563	Bos taurus	86.99	0.00e+00	764.00
IUUC-Bci-013690	Botrytis cinerea	56.60	4.00e-12	66.60
IUUC-Cfa-020718	Canis familiaris	89.73	0.00e+00	837.00
IUUC-Cpo-022303	Cavia porcellus	84.71	0.00e+00	852.00
IUUC-Csa-023431	Chlorocebus sabaeus	88.93	0.00e+00	826.00
IUUC-Cin-025677	Ciona intestinalis	60.66	3.00e-106	379.00
IUUC-Csv-026140	Ciona savignyi	63.87	4.00e-99	355.00
IUUC-Dre-028012	Danio rerio	56.29	2.00e-132	465.00
IUUC-Dno-029332	Dasypus novemcinctus	79.32	0.00e+00	657.00
IUUC-Dse-031182	Dothistroma septosporum	36.51	1.00e-10	62.00
IUUC-Eca-033801	Equus caballus	89.49	0.00e+00	796.00
IUUC-Fal-036775	Ficedula albicollis	81.24	0.00e+00	692.00
IUUC-Fox-037778	Fusarium oxysporum	61.40	9.00e-15	75.50
IUUC-Gmo-038507	Gadus morhua	58.23	6.00e-21	95.10
IUUC-Gga-040568	Gallus gallus	82.44	0.00e+00	706.00
IUUC-Gac-042253	Gasterosteus aculeatus	53.97	7.00e-93	334.00
IUUC-Hsa-046818	Homo sapiens	89.13	0.00e+00	827.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	86.09	0.00e+00	750.00
IUUC-Lch-050199	Latimeria chalumnae	67.97	7.00e-115	407.00
IUUC-Loc-052855	Lepisosteus oculatus	73.68	1.00e-125	443.00
IUUC-Lma-053035	Leptosphaeria maculans	59.18	3.00e-12	67.40
IUUC-Laf-053866	Loxodonta africana	87.17	0.00e+00	830.00
IUUC-Mcc-055515	Macaca mulatta	88.93	0.00e+00	799.00
IUUC-Mga-059791	Meleagris gallopavo	78.83	0.00e+00	703.00
IUUC-Mmr-061147	Microcebus murinus	88.38	0.00e+00	754.00
IUUC-Mdo-062660	Monodelphis domestica	58.27	2.00e-142	499.00
IUUC-Mmu-064023	Mus musculus	87.42	0.00e+00	806.00
IUUC-Mpu-065867	Mustela putorius furo	84.74	0.00e+00	705.00
IUUC-Mlu-067704	Myotis lucifugus	82.66	0.00e+00	672.00
IUUC-Ont-071873	Oreochromis niloticus	81.19	1.00e-145	509.00
IUUC-Oan-073528	Ornithorhynchus anatinus	80.80	1.00e-161	561.00
IUUC-Oga-088028	Otolemur garnettii	87.12	0.00e+00	808.00
IUUC-Oar-090203	Ovis aries	86.79	0.00e+00	744.00
IUUC-Pan-092594	Papio anubis	84.74	0.00e+00	743.00
IUUC-Psi-093389	Pelodiscus sinensis	81.41	0.00e+00	715.00
IUUC-Pma-094161	Petromyzon marinus	41.98	2.00e-60	227.00
IUUC-Pfo-096269	Poecilia formosa	63.84	8.00e-102	363.00
IUUC-Pab-097913	Pongo abelii	82.09	0.00e+00	702.00
IUUC-Rno-105489	Rattus norvegicus	86.82	0.00e+00	758.00
IUUC-Sha-107308	Sarcophilus harrisii	72.52	2.00e-172	598.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	55.17	1.00e-14	75.10
IUUC-Tgu-117049	Taeniopygia guttata	75.10	0.00e+00	627.00
IUUC-Tru-118718	Takifugu rubripes	75.82	2.00e-132	465.00
IUUC-Tni-120535	Tetraodon nigroviridis	70.82	9.00e-120	423.00
IUUC-Tre-122167	Trichoderma reesei	59.18	1.00e-11	65.10
IUUC-Tvi-122614	Trichoderma virens	59.18	1.00e-11	65.50
IUUC-Vda-129766	Verticillium dahliae	57.89	1.00e-13	72.00
IUUC-Xtr-131797	Xenopus tropicalis	64.31	2.00e-171	595.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence