iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021376

Ensembl Protein ID

ENSCPOP00000002948.2

UniProt Accession

H0V0G0; H0V0G0_CAVPO

Genbank Protein ID

ENSCPOP00000002948

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02040430

Gene Name

GNB4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000003258.3	ENSCPOT00000003301.2	ENSCPOP00000002948.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-39	131.2	224	258
UBD/Beta-Prp	8.20e-52	176.2	46	267

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH +++++++f ++   +++GsdD t++++Dlr +
   Q: 224  GHVSDINAVSFfPNgYAFATGSDDATCRLFDLRAD 258
           8*********99885679**************987 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
            + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   +h++   ++ v+++++ psg++++ G+ d++  +++l+t++    
   Q: 46   RTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVR 134
           446899*****************************************************************************987776 PP
   S: 132  ...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
               l gh+g  +c ++ + ++ +v++s D+t+ lWd++t++  +t+tg h ++v sls++++ + +vsg++d + klwd++ g c ++
   Q: 135  vsrELPGHTGYLSCCRFLD-DSQIVTSSGDTTCALWDIETAQQTTTFTG-HSGDVMSLSLSPDLRTFVSGACDASSKLWDIRDGMCRQS 221
           6779*************99.67789***********************9.*************************************** PP
   S: 218  lnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
           ++gh + ++ v f+pn+  +++gs+D + r++dlr ++ l  +++ 
   Q: 222  FTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHD 267
           **************************************99888874 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MSELEQLRQE AEQLRNQIQD ARKACNDATL VQITSNMDSV GRIQMRTRRT LRGHLAKIYA 60
MHWGYDSRLL VSASQDGKLI IWDSYTTNKM HAIPLRSSWV MTCAYAPSGN YVACGGLDNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTGAAC TAGAACAACT GAGGCAGGAA GCGGAGCAGC TGCGGAATCA GATCCAGGTG 60
AGAACATTTT CATTTCTTTC AAAAGTTTAA TGCTTTTTGT CTAGTATAAG GCTAAAATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0007165--P:signal transduction
GO:0021762--P:substantia nigra development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001727	Ailuropoda melanoleuca	98.76	0.00e+00	664.00
IUUC-Apl-003923	Anas platyrhynchos	93.83	5.00e-175	606.00
IUUC-Aca-004754	Anolis carolinensis	93.81	1.00e-175	608.00
IUUC-Ate-010520	Aspergillus terreus	61.76	8.00e-110	389.00
IUUC-Bta-013200	Bos taurus	98.76	0.00e+00	662.00
IUUC-Cja-019845	Callithrix jacchus	98.76	0.00e+00	663.00
IUUC-Cfa-020395	Canis familiaris	98.76	0.00e+00	664.00
IUUC-Csa-023295	Chlorocebus sabaeus	99.07	0.00e+00	665.00
IUUC-Cho-024766	Choloepus hoffmanni	98.46	0.00e+00	665.00
IUUC-Dno-029802	Dasypus novemcinctus	98.36	1.00e-180	625.00
IUUC-Dme-031748	Drosophila melanogaster	81.47	6.00e-173	599.00
IUUC-Ete-032710	Echinops telfairi	95.78	3.00e-179	620.00
IUUC-Eca-033628	Equus caballus	98.45	0.00e+00	662.00
IUUC-Eeu-034978	Erinaceus europaeus	97.07	2.00e-157	547.00
IUUC-Fal-037616	Ficedula albicollis	94.12	3.00e-176	610.00
IUUC-Gmo-039556	Gadus morhua	91.95	1.00e-180	624.00
IUUC-Gga-040249	Gallus gallus	94.12	3.00e-176	610.00
IUUC-Gac-041805	Gasterosteus aculeatus	91.02	2.00e-180	624.00
IUUC-Ggo-044954	Gorilla gorilla	98.76	0.00e+00	663.00
IUUC-Hsa-046105	Homo sapiens	99.07	0.00e+00	665.00
IUUC-Itr-048623	Ictidomys tridecemlineatus	99.07	0.00e+00	662.00
IUUC-Mcc-055787	Macaca mulatta	99.07	0.00e+00	665.00
IUUC-Mga-060050	Meleagris gallopavo	93.83	5.00e-175	606.00
IUUC-Mmr-060931	Microcebus murinus	99.07	0.00e+00	665.00
IUUC-Mdo-063055	Monodelphis domestica	93.50	2.00e-175	608.00
IUUC-Mmu-064368	Mus musculus	96.28	0.00e+00	650.00
IUUC-Mpu-066358	Mustela putorius furo	98.76	0.00e+00	664.00
IUUC-Mlu-067328	Myotis lucifugus	97.83	0.00e+00	657.00
IUUC-Nle-069612	Nomascus leucogenys	99.07	0.00e+00	665.00
IUUC-Ont-071287	Oreochromis niloticus	91.95	2.00e-180	624.00
IUUC-Oan-072913	Ornithorhynchus anatinus	94.43	3.00e-177	613.00
IUUC-Ocu-074126	Oryctolagus cuniculus	98.45	0.00e+00	667.00
IUUC-Ola-087297	Oryzias latipes	91.69	0.00e+00	627.00
IUUC-Oar-089360	Ovis aries	98.76	0.00e+00	663.00
IUUC-Ptr-091437	Pan troglodytes	99.07	0.00e+00	665.00
IUUC-Pan-092195	Papio anubis	98.76	0.00e+00	663.00
IUUC-Psi-093718	Pelodiscus sinensis	94.12	3.00e-176	610.00
IUUC-Pfo-096251	Poecilia formosa	91.64	7.00e-180	622.00
IUUC-Sha-106534	Sarcophilus harrisii	93.50	9.00e-176	608.00
IUUC-Sja-107891	Schizosaccharomyces japonicus	35.48	1.00e-59	223.00
IUUC-Spo-108352	Schizosaccharomyces pombe	41.69	1.00e-69	256.00
IUUC-Smo-108835	Selaginella moellendorffii	43.58	2.00e-74	272.00
IUUC-Sar-113642	Sorex araneus	98.16	2.00e-160	558.00
IUUC-Tgu-117198	Taeniopygia guttata	94.12	3.00e-176	610.00
IUUC-Tru-118399	Takifugu rubripes	91.33	3.00e-180	624.00
IUUC-Tsy-119354	Tarsius syrichta	95.98	0.00e+00	647.00
IUUC-Ttr-129243	Tursiops truncatus	99.07	0.00e+00	665.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence