iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094533

UUCD1 version

UUC-PeM-00529

Ensembl Protein ID

ENSPMAP00000004641.1

UniProt Accession

S4RHF9; S4RHF9_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000004091.1	ENSPMAT00000004660.1	ENSPMAP00000004641.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.70e-116	387.6	273	922
ULD/UDP/UBQ/UBQ_Other	2.10e-11	42.8	154	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+ ++le  + ++ln++np ++ ge+++++++l++++w+++ +++ pr+++++++++a++fsgy+
   Q: 273  CGLSNLGNTCFMNSALQCLSNTPPLTTYFLEdAYLKELNRDNPLGMRGEIACAYADLIKQMWSGSYSSTVPRSFKTQVGRFAPQFSGYQ 361
           7******************************99******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ ++kp+ e+++++   ++d+     a++++ k+n+s+i+d+F+g +ks+++c++c++vs++++pf++l
   Q: 362  QQDSQELLAFLLDGLHEDLNRIRKKPYVELKDAE--GRDDKvvaqeAWDNHRKRNDSIIVDIFHGLFKSTLICPDCAKVSVTFDPFCYL 448
           ***************************9998776..4444444666******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p k+e++ e                                                                            
   Q: 449  TLPLPIKTERAVEvtlvwqdpkskptmyrvvvpkmgsvsdlcaalglladvpkenmvvtdvynhrfhkiftmneplngindrddifvfe 537
           *********9999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 538  vadedtapdhvhvavymrerktsrsgyssscastslfglpllvsvprstttleglyehltqcmdyyenltklteprhghlhlnisgnns 626
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 627  ssehmeddtsnqdvpsstvtgdpeqelasesesdadqqivpsrpkdstravptytalggkgqrcghkrrplfsihpvnsygntenhait 715
           ***************************************************************************************** PP
   S: 186  ............................................................slqdcLesftkeeelegenkyycekckkk 214
                                                                       +l++c+e ft++eel   + +yc++ckk+
   Q: 716  ddgkpikfqgailsciaartylalewdsetrarfynnnvdkefekhdsmlaqplkkknpvKLKECIELFTTKEELAATDPWYCPNCKKH 804
           ***************************************************************************************** PP
   S: 215  qeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkne 302
           ++a+kk++l+ lP+vL++hLkRfs++++   r k+++ v+fp++ Ld+s+f++ ++   +++++Y+Liav +H+G++++GHY+ay+kn+
   Q: 805  KQATKKFDLWALPKVLVVHLKRFSYNKY--WRDKLDTLVDFPIRdLDMSEFVIGTQ---DVPCTYDLIAVSNHYGGMGGGHYTAYAKNK 888
           ***********************99885..556*********************44...349**************************6 PP
   S: 303  kgk.WllfdDskVtevkeeevleetgstaYvlfYkrr 338
            ++ W++fdDs+V+++ e+++++   + aYvlfY+rr
   Q: 889  GENsWYYFDDSSVSSSAEDQIVS---KAAYVLFYQRR 922
           5557*******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   kvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           +++++dt+ ++ ++++k+++ip + + rL++k      ++L ++ ktL+d+gl++g+++++++k+++
   Q: 154  QFSKADTIDTIEKEMRKLFHIPeEKETRLWNKymtntYEPLnKPEKTLQDVGLFQGQVLVIEQKNED 220
           3789******************777*******999888889**********************9986 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

MAEGGAADLA TQKGDIGALL KTPLKKGDTW YLVDCHWFKQ WKKHVGFDSW EVYSAADQST 60
YPGPIDNSGL FKVGPDENLE GLKDNLIDEL DYILVPTEAW RKLVEWYGYT ADQEPVERKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGG GCGGCGCTGC GGACCTCGCG ACGCAGAAGG GCGACATCGG CGCCCTGCTC 60
AAGACTCCGC TCAAGAAAGG CGACACATGG TGGGCTGGGG AGAGTGAGAG GGGAGGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0034122--P:negative regulation of toll-like receptor signaling pathway
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	53.06	2.00e-74	272.00
IUUC-Aml-001852	Ailuropoda melanoleuca	60.06	0.00e+00	1112.00
IUUC-Atr-002955	Amborella trichopoda	39.84	7.00e-121	426.00
IUUC-Apl-003249	Anas platyrhynchos	59.63	0.00e+00	1030.00
IUUC-Aca-004261	Anolis carolinensis	59.15	0.00e+00	1058.00
IUUC-Aly-006315	Arabidopsis lyrata	36.78	4.00e-97	347.00
IUUC-Ath-007560	Arabidopsis thaliana	40.74	2.00e-131	462.00
IUUC-Ago-007911	Ashbya gossypii	39.77	6.00e-64	238.00
IUUC-Ani-009479	Aspergillus nidulans	45.16	5.00e-54	205.00
IUUC-Ang-009562	Aspergillus niger	40.51	3.00e-56	213.00
IUUC-Ame-010757	Astyanax mexicanus	57.66	0.00e+00	887.00
IUUC-Bgr-012277	Blumeria graminis	39.84	3.00e-64	239.00
IUUC-Bta-013128	Bos taurus	60.58	0.00e+00	1114.00
IUUC-Bdi-014013	Brachypodium distachyon	35.56	1.00e-145	508.00
IUUC-Bol-015570	Brassica oleracea	37.87	2.00e-107	381.00
IUUC-Bra-017029	Brassica rapa	35.87	1.00e-140	492.00
IUUC-Cel-018203	Caenorhabditis elegans	58.29	7.00e-69	254.00
IUUC-Cja-019222	Callithrix jacchus	60.27	0.00e+00	1113.00
IUUC-Cfa-020035	Canis familiaris	59.96	0.00e+00	1110.00
IUUC-Cpo-022071	Cavia porcellus	60.94	0.00e+00	1085.00
IUUC-Csa-023882	Chlorocebus sabaeus	60.27	0.00e+00	1114.00
IUUC-Cho-024595	Choloepus hoffmanni	52.46	0.00e+00	656.00
IUUC-Cin-025292	Ciona intestinalis	45.34	0.00e+00	743.00
IUUC-Csv-026109	Ciona savignyi	42.36	0.00e+00	669.00
IUUC-Cne-026852	Cryptococcus neoformans	42.69	9.00e-75	274.00
IUUC-Cme-027338	Cyanidioschyzon merolae	57.00	8.00e-67	247.00
IUUC-Dre-027869	Danio rerio	55.52	0.00e+00	723.00
IUUC-Dor-030956	Dipodomys ordii	53.60	0.00e+00	910.00
IUUC-Dse-031432	Dothistroma septosporum	42.45	1.00e-60	227.00
IUUC-Ete-032970	Echinops telfairi	54.16	2.00e-177	615.00
IUUC-Eca-034340	Equus caballus	59.75	0.00e+00	1065.00
IUUC-Eeu-034488	Erinaceus europaeus	55.35	0.00e+00	751.00
IUUC-Fca-035552	Felis catus	60.06	0.00e+00	1100.00
IUUC-Fal-036618	Ficedula albicollis	58.94	0.00e+00	1027.00
IUUC-Fox-037986	Fusarium oxysporum	42.66	2.00e-63	236.00
IUUC-Fso-038291	Fusarium solani	43.62	3.00e-66	246.00
IUUC-Gmo-038866	Gadus morhua	55.92	0.00e+00	689.00
IUUC-Ggr-039740	Gaeumannomyces graminis	43.56	2.00e-62	233.00
IUUC-Gga-041146	Gallus gallus	59.85	0.00e+00	1072.00
IUUC-Gac-041679	Gasterosteus aculeatus	57.98	0.00e+00	1061.00
IUUC-Gma-043077	Glycine max	35.84	2.00e-146	511.00
IUUC-Ggo-045002	Gorilla gorilla	59.75	0.00e+00	1067.00
IUUC-Hsa-046052	Homo sapiens	60.27	0.00e+00	1114.00
IUUC-Hvu-047108	Hordeum vulgare	52.61	1.00e-75	276.00
IUUC-Itr-048306	Ictidomys tridecemlineatus	60.66	0.00e+00	1112.00
IUUC-Kpa-049332	Komagataella pastoris	30.35	1.00e-69	257.00
IUUC-Lch-050107	Latimeria chalumnae	59.45	0.00e+00	1103.00
IUUC-Lpe-051185	Leersia perrieri	39.04	4.00e-123	434.00
IUUC-Loc-052105	Lepisosteus oculatus	58.62	0.00e+00	1024.00
IUUC-Laf-053645	Loxodonta africana	60.47	0.00e+00	1118.00
IUUC-Mcc-055586	Macaca mulatta	60.27	0.00e+00	1114.00
IUUC-Meu-056742	Macropus eugenii	53.05	0.00e+00	675.00
IUUC-Mpo-057486	Magnaporthe poae	42.57	1.00e-60	227.00
IUUC-Mtr-058138	Medicago truncatula	35.62	3.00e-146	511.00
IUUC-Mga-060162	Meleagris gallopavo	59.92	0.00e+00	1074.00
IUUC-Mvi-060324	Microbotryum violaceum	33.51	6.00e-79	288.00
IUUC-Mmr-061105	Microcebus murinus	60.47	0.00e+00	1117.00
IUUC-Mdo-062107	Monodelphis domestica	60.62	0.00e+00	1108.00
IUUC-Mmu-063662	Mus musculus	59.75	0.00e+00	1107.00
IUUC-Mac-065239	Musa acuminata	33.10	4.00e-127	447.00
IUUC-Mpu-065868	Mustela putorius furo	58.85	0.00e+00	1099.00
IUUC-Mlu-068000	Myotis lucifugus	57.89	0.00e+00	1038.00
IUUC-Ncr-068879	Neurospora crassa	47.17	2.00e-60	226.00
IUUC-Nle-069874	Nomascus leucogenys	61.13	0.00e+00	1111.00
IUUC-Opr-071212	Ochotona princeps	57.19	0.00e+00	1028.00
IUUC-Ont-071834	Oreochromis niloticus	59.39	0.00e+00	1059.00
IUUC-Oan-073363	Ornithorhynchus anatinus	56.03	0.00e+00	720.00
IUUC-Ocu-074573	Oryctolagus cuniculus	60.27	0.00e+00	1113.00
IUUC-Oba-075553	Oryza barthii	39.58	1.00e-124	439.00
IUUC-Obr-076416	Oryza brachyantha	38.54	2.00e-115	408.00
IUUC-Ogl-077583	Oryza glaberrima	39.58	1.00e-124	439.00
IUUC-Ogu-078422	Oryza glumaepatula	40.00	1.00e-123	435.00
IUUC-Oin-079300	Oryza indica	39.73	6.00e-126	443.00
IUUC-Olo-080315	Oryza longistaminata	35.57	6.00e-143	499.00
IUUC-Ome-081271	Oryza meridionalis	35.71	3.00e-145	507.00
IUUC-Oni-082834	Oryza nivara	39.42	8.00e-124	436.00
IUUC-Opu-083691	Oryza punctata	34.64	9.00e-140	489.00
IUUC-Oru-084820	Oryza rufipogon	39.42	9.00e-124	436.00
IUUC-Osa-086139	Oryza sativa	35.75	3.00e-144	504.00
IUUC-Olu-087717	Ostreococcus lucimarinus	39.30	3.00e-124	437.00
IUUC-Oga-089022	Otolemur garnettii	60.79	0.00e+00	1112.00
IUUC-Oar-089767	Ovis aries	60.16	0.00e+00	1109.00
IUUC-Ptr-091319	Pan troglodytes	60.58	0.00e+00	1116.00
IUUC-Pan-091968	Papio anubis	60.27	0.00e+00	1114.00
IUUC-Psi-093849	Pelodiscus sinensis	59.78	0.00e+00	1030.00
IUUC-Ppa-095825	Physcomitrella patens	34.52	5.00e-24	105.00
IUUC-Pfo-097110	Poecilia formosa	59.14	0.00e+00	1068.00
IUUC-Pab-098664	Pongo abelii	60.27	0.00e+00	1114.00
IUUC-Pop-099801	Populus trichocarpa	35.90	1.00e-146	512.00
IUUC-Ppe-101587	Prunus persica	40.78	6.00e-132	463.00
IUUC-Pva-102394	Pteropus vampyrus	59.03	0.00e+00	1080.00
IUUC-Pgr-103546	Puccinia graminis	31.44	3.00e-84	305.00
IUUC-Ptt-103847	Puccinia triticina	43.38	6.00e-62	231.00
IUUC-Pte-104102	Pyrenophora teres	37.50	1.00e-55	211.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	37.16	1.00e-56	214.00
IUUC-Rno-105383	Rattus norvegicus	60.37	0.00e+00	1110.00
IUUC-Sha-107393	Sarcophilus harrisii	60.51	0.00e+00	1107.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	35.06	9.00e-77	280.00
IUUC-Spo-108291	Schizosaccharomyces pombe	32.25	4.00e-75	275.00
IUUC-Smo-108686	Selaginella moellendorffii	44.48	5.00e-79	287.00
IUUC-Sit-109948	Setaria italica	34.96	3.00e-135	474.00
IUUC-Sly-111726	Solanum lycopersicum	38.17	5.00e-90	324.00
IUUC-Sar-113498	Sorex araneus	60.92	0.00e+00	1108.00
IUUC-Sbi-114874	Sorghum bicolor	35.18	3.00e-138	484.00
IUUC-Sre-115130	Sporisorium reilianum	31.36	5.00e-91	328.00
IUUC-Ssc-115285	Sus scrofa	60.27	0.00e+00	1113.00
IUUC-Tgu-116529	Taeniopygia guttata	59.96	0.00e+00	1074.00
IUUC-Tru-118298	Takifugu rubripes	58.67	0.00e+00	1057.00
IUUC-Tsy-119117	Tarsius syrichta	53.23	0.00e+00	627.00
IUUC-Tni-120093	Tetraodon nigroviridis	56.35	0.00e+00	1001.00
IUUC-Tca-121001	Theobroma cacao	35.27	3.00e-149	521.00
IUUC-Tre-121888	Trichoderma reesei	46.77	1.00e-64	240.00
IUUC-Tvi-122422	Trichoderma virens	44.11	7.00e-59	221.00
IUUC-Tae-125811	Triticum aestivum	40.79	2.00e-118	418.00
IUUC-Tur-126478	Triticum urartu	52.82	3.00e-75	275.00
IUUC-Tme-127062	Tuber melanosporum	32.55	5.00e-77	281.00
IUUC-Tbe-127672	Tupaia belangeri	55.48	0.00e+00	732.00
IUUC-Uma-129498	Ustilago maydis	35.98	1.00e-114	407.00
IUUC-Vda-129781	Verticillium dahliae	46.79	2.00e-65	243.00
IUUC-Vpa-130469	Vicugna pacos	59.53	0.00e+00	1055.00
IUUC-Vvi-131010	Vitis vinifera	36.08	2.00e-139	488.00
IUUC-Xtr-132305	Xenopus tropicalis	56.66	0.00e+00	1027.00
IUUC-Xma-133550	Xiphophorus maculatus	59.50	0.00e+00	1065.00
IUUC-Zma-135699	Zea mays	35.04	1.00e-138	486.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence