iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045257

Ensembl Protein ID

ENSGGOP00000008353.2

UniProt Accession

G3QZN8; G3QZN8_GORGO

Protein Name

Uncharacterized protein

Gene Name

RNF14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000008542.2	ENSGGOT00000008583.2	ENSGGOP00000008353.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	6.60e-56	190.0	220	433

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++C++e+  +e++++leC+h++Ck+Clk+y+e++i++gqv++++cp+++cp+ +++ ++ke lve+el++ry++lll+++++ +a++ +
   Q: 220  CNICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCPSVATPGQVKE-LVEAELFARYDRLLLQSSLDLMADVVY 308
           **************************************************************.7************************** PP
   S: 91   cpapdCslvvllekeaekleve.cekcgkefCveCkeewHeglsCkelkeklakteeek........................eeaeske 155
           cp+p+C+l+v++e+     ++  c++c+++fC+ C+ ++H  + Ck ++ekl++ ++e+                        ee+eske
   Q: 309  CPRPCCQLPVMQEPG---CTMGiCSSCNFAFCTLCRLTYHGVSPCKVTAEKLMDLRNEYlqadeankrlldqrygkrviqkalEEMESKE 395
           *************95...33337**********************************99******************************* PP
   S: 156  lleanskkCpkCkvyieknegCnhmtCakCkaefCwlC 193
           +le+nsk+Cp+C ++iek +gCn+mtC+ C+++fCw+C
   Q: 396  WLEKNSKSCPCCGTPIEKLDGCNKMTCTGCMQYFCWIC 433
           ************************************** PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSSEDREAQE DELLALASIY DGDEFRKAES VQGGETRIYL DLPQNFKIFV SGNSNECLQN 60
SGFEYSICFL PPLVLNFELP PDYPSSSPPS FTLSGKWLSP TQLSALCKHL DNLWEEHRGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGGCGGCC GCACCAGCGG GATCCGCCTG GCTCAGCTGA CAGCTCCCGA GAACGGAAGA 60
GGCGGCGCGC CGGTTGAGCA GGGCGTCTCT AGGCCTGGTC GGCTGGCGGC GGTGAGTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50908--RWD
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF05773--RWD

SMART

SM00647--IBR
SM00591--RWD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0060765--P:regulation of androgen receptor signaling pathway

KEGG

ggo:101139553

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001130	Aegilops tauschii	29.42	4.00e-50	192.00
IUUC-Aml-001458	Ailuropoda melanoleuca	96.01	0.00e+00	915.00
IUUC-Atr-002560	Amborella trichopoda	29.98	1.00e-44	174.00
IUUC-Apl-003680	Anas platyrhynchos	82.28	0.00e+00	776.00
IUUC-Aca-005000	Anolis carolinensis	71.43	0.00e+00	668.00
IUUC-Aly-006288	Arabidopsis lyrata	30.80	2.00e-53	203.00
IUUC-Ath-006719	Arabidopsis thaliana	31.39	8.00e-53	201.00
IUUC-Acl-008213	Aspergillus clavatus	25.05	3.00e-30	126.00
IUUC-Afl-008433	Aspergillus flavus	25.00	1.00e-30	128.00
IUUC-Afu-008772	Aspergillus fumigatus	25.27	4.00e-32	132.00
IUUC-Ani-009249	Aspergillus nidulans	25.65	4.00e-33	135.00
IUUC-Ang-009757	Aspergillus niger	27.99	8.00e-37	148.00
IUUC-Aor-009963	Aspergillus oryzae	25.05	2.00e-30	127.00
IUUC-Ate-010460	Aspergillus terreus	25.11	5.00e-31	129.00
IUUC-Ame-011312	Astyanax mexicanus	58.61	2.00e-145	508.00
IUUC-Bgr-012052	Blumeria graminis	23.74	4.00e-29	122.00
IUUC-Bta-013529	Bos taurus	95.57	0.00e+00	919.00
IUUC-Bci-013729	Botrytis cinerea	25.16	8.00e-27	115.00
IUUC-Bdi-014940	Brachypodium distachyon	31.67	6.00e-48	185.00
IUUC-Bra-016998	Brassica rapa	29.69	1.00e-49	191.00
IUUC-Cel-018547	Caenorhabditis elegans	31.59	5.00e-51	195.00
IUUC-Cja-019791	Callithrix jacchus	97.05	0.00e+00	931.00
IUUC-Cfa-020403	Canis familiaris	95.57	0.00e+00	919.00
IUUC-Cpo-022229	Cavia porcellus	90.34	0.00e+00	857.00
IUUC-Cre-022601	Chlamydomonas reinhardtii	34.88	5.00e-29	120.00
IUUC-Csa-024115	Chlorocebus sabaeus	98.73	0.00e+00	940.00
IUUC-Cho-024911	Choloepus hoffmanni	95.78	0.00e+00	920.00
IUUC-Cin-025578	Ciona intestinalis	41.86	3.00e-98	352.00
IUUC-Csv-026355	Ciona savignyi	40.10	3.00e-82	298.00
IUUC-Cgl-026439	Colletotrichum gloeosporioides	24.04	6.00e-25	108.00
IUUC-Cne-026782	Cryptococcus neoformans	26.25	4.00e-31	129.00
IUUC-Dre-027380	Danio rerio	56.47	2.00e-152	532.00
IUUC-Dno-029640	Dasypus novemcinctus	95.37	0.00e+00	911.00
IUUC-Dor-030681	Dipodomys ordii	94.51	0.00e+00	906.00
IUUC-Dse-031208	Dothistroma septosporum	24.76	2.00e-31	130.00
IUUC-Ete-033122	Echinops telfairi	60.92	2.00e-134	472.00
IUUC-Eca-033755	Equus caballus	94.00	0.00e+00	887.00
IUUC-Eeu-035034	Erinaceus europaeus	97.95	6.00e-73	268.00
IUUC-Fca-036461	Felis catus	95.78	0.00e+00	920.00
IUUC-Fal-037516	Ficedula albicollis	81.68	0.00e+00	775.00
IUUC-Fso-038307	Fusarium solani	25.16	4.00e-25	109.00
IUUC-Gmo-039563	Gadus morhua	57.27	5.00e-148	517.00
IUUC-Ggr-039920	Gaeumannomyces graminis	25.48	5.00e-23	102.00
IUUC-Gga-040331	Gallus gallus	80.68	0.00e+00	754.00
IUUC-Gac-042164	Gasterosteus aculeatus	59.45	6.00e-160	556.00
IUUC-Gma-044080	Glycine max	32.33	8.00e-57	214.00
IUUC-Hsa-046887	Homo sapiens	99.57	0.00e+00	919.00
IUUC-Hvu-047317	Hordeum vulgare	29.49	7.00e-49	188.00
IUUC-Itr-048199	Ictidomys tridecemlineatus	95.15	0.00e+00	915.00
IUUC-Lch-050155	Latimeria chalumnae	64.12	2.00e-164	572.00
IUUC-Lpe-051669	Leersia perrieri	30.65	6.00e-39	155.00
IUUC-Loc-051779	Lepisosteus oculatus	60.27	7.00e-155	540.00
IUUC-Lma-052969	Leptosphaeria maculans	23.68	6.00e-30	125.00
IUUC-Laf-053488	Loxodonta africana	92.62	0.00e+00	886.00
IUUC-Mcc-054701	Macaca mulatta	99.13	0.00e+00	915.00
IUUC-Meu-056577	Macropus eugenii	82.91	7.00e-127	447.00
IUUC-Mor-057157	Magnaporthe oryzae	23.16	2.00e-27	117.00
IUUC-Mpo-057518	Magnaporthe poae	23.70	2.00e-27	117.00
IUUC-Mtr-058125	Medicago truncatula	29.30	7.00e-46	178.00
IUUC-Mga-059906	Meleagris gallopavo	80.47	0.00e+00	751.00
IUUC-Mvi-060374	Microbotryum violaceum	31.43	2.00e-33	136.00
IUUC-Mmr-061786	Microcebus murinus	96.41	0.00e+00	922.00
IUUC-Mdo-062453	Monodelphis domestica	90.13	0.00e+00	833.00
IUUC-Mmu-063521	Mus musculus	90.04	0.00e+00	810.00
IUUC-Mac-065119	Musa acuminata	30.15	3.00e-40	159.00
IUUC-Mpu-066274	Mustela putorius furo	95.36	0.00e+00	917.00
IUUC-Mlu-067202	Myotis lucifugus	92.17	0.00e+00	845.00
IUUC-Nfi-068564	Neosartorya fischeri	24.62	5.00e-31	129.00
IUUC-Ncr-068823	Neurospora crassa	24.89	6.00e-31	129.00
IUUC-Nle-068987	Nomascus leucogenys	99.78	0.00e+00	922.00
IUUC-Opr-070453	Ochotona princeps	91.77	0.00e+00	877.00
IUUC-Ont-072611	Oreochromis niloticus	57.98	7.00e-159	553.00
IUUC-Oan-073738	Ornithorhynchus anatinus	82.17	0.00e+00	747.00
IUUC-Ocu-074396	Oryctolagus cuniculus	94.30	0.00e+00	903.00
IUUC-Oba-075472	Oryza barthii	31.87	7.00e-43	168.00
IUUC-Obr-076277	Oryza brachyantha	31.65	7.00e-45	175.00
IUUC-Ogl-077046	Oryza glaberrima	31.56	2.00e-41	164.00
IUUC-Ogu-078634	Oryza glumaepatula	31.87	4.00e-43	169.00
IUUC-Oin-080080	Oryza indica	29.57	4.00e-44	172.00
IUUC-Olo-080828	Oryza longistaminata	29.00	9.00e-42	166.00
IUUC-Ome-081387	Oryza meridionalis	29.57	8.00e-47	181.00
IUUC-Oni-082934	Oryza nivara	31.87	4.00e-43	169.00
IUUC-Opu-083719	Oryza punctata	28.81	8.00e-41	161.00
IUUC-Oru-084518	Oryza rufipogon	31.87	4.00e-43	169.00
IUUC-Ola-087312	Oryzias latipes	58.88	2.00e-156	545.00
IUUC-Olu-087661	Ostreococcus lucimarinus	28.54	2.00e-45	176.00
IUUC-Oga-089129	Otolemur garnettii	96.41	0.00e+00	919.00
IUUC-Oar-089839	Ovis aries	95.36	0.00e+00	918.00
IUUC-Ptr-091626	Pan troglodytes	99.78	0.00e+00	921.00
IUUC-Pan-092798	Papio anubis	99.13	0.00e+00	915.00
IUUC-Psi-093253	Pelodiscus sinensis	81.82	0.00e+00	784.00
IUUC-Pma-094512	Petromyzon marinus	54.96	1.00e-143	503.00
IUUC-Pno-094937	Phaeosphaeria nodorum	23.25	8.00e-29	121.00
IUUC-Ppa-095211	Physcomitrella patens	30.30	6.00e-53	202.00
IUUC-Pfo-097049	Poecilia formosa	53.18	3.00e-138	484.00
IUUC-Pab-097911	Pongo abelii	99.57	0.00e+00	919.00
IUUC-Pop-099841	Populus trichocarpa	31.28	5.00e-49	189.00
IUUC-Pca-100814	Procavia capensis	74.05	0.00e+00	657.00
IUUC-Ppe-101972	Prunus persica	30.36	4.00e-49	189.00
IUUC-Pva-103038	Pteropus vampyrus	95.15	0.00e+00	911.00
IUUC-Pgr-103277	Puccinia graminis	32.82	9.00e-39	154.00
IUUC-Ptt-103855	Puccinia triticina	30.48	9.00e-35	141.00
IUUC-Pte-104113	Pyrenophora teres	23.25	8.00e-26	111.00
IUUC-Pyt-104619	Pyrenophora triticirepentis	25.56	7.00e-27	115.00
IUUC-Rno-106003	Rattus norvegicus	90.48	0.00e+00	828.00
IUUC-Sce-106287	Saccharomyces cerevisiae	27.45	3.00e-23	102.00
IUUC-Sha-106652	Sarcophilus harrisii	89.80	0.00e+00	841.00
IUUC-Spo-108167	Schizosaccharomyces pombe	31.22	5.00e-51	195.00
IUUC-Ssl-108396	Sclerotinia sclerotiorum	25.00	9.00e-09	55.80
IUUC-Smo-109393	Selaginella moellendorffii	30.60	2.00e-47	183.00
IUUC-Sit-110529	Setaria italica	33.77	7.00e-42	165.00
IUUC-Sly-111829	Solanum lycopersicum	29.93	1.00e-52	201.00
IUUC-Stu-112811	Solanum tuberosum	30.16	2.00e-53	203.00
IUUC-Sar-113259	Sorex araneus	89.93	3.00e-138	485.00
IUUC-Sbi-114591	Sorghum bicolor	32.38	7.00e-35	142.00
IUUC-Sre-115227	Sporisorium reilianum	28.66	4.00e-37	149.00
IUUC-Ssc-115293	Sus scrofa	93.88	0.00e+00	901.00
IUUC-Tgu-117335	Taeniopygia guttata	82.32	0.00e+00	774.00
IUUC-Tru-118458	Takifugu rubripes	56.99	2.00e-154	538.00
IUUC-Tsy-119475	Tarsius syrichta	87.76	0.00e+00	812.00
IUUC-Tni-119827	Tetraodon nigroviridis	56.69	4.00e-153	534.00
IUUC-Tca-121023	Theobroma cacao	31.58	5.00e-50	192.00
IUUC-Tre-121965	Trichoderma reesei	24.03	2.00e-29	123.00
IUUC-Tvi-122564	Trichoderma virens	21.59	1.00e-26	114.00
IUUC-Tae-124793	Triticum aestivum	33.04	5.00e-39	155.00
IUUC-Tur-126258	Triticum urartu	30.67	1.00e-45	177.00
IUUC-Tbe-127227	Tupaia belangeri	71.94	1.00e-76	280.00
IUUC-Ttr-128984	Tursiops truncatus	73.21	0.00e+00	632.00
IUUC-Uma-129565	Ustilago maydis	27.36	4.00e-35	143.00
IUUC-Vpa-130301	Vicugna pacos	96.41	0.00e+00	922.00
IUUC-Vvi-131244	Vitis vinifera	31.00	3.00e-52	199.00
IUUC-Xtr-132880	Xenopus tropicalis	59.96	5.00e-165	573.00
IUUC-Xma-134055	Xiphophorus maculatus	58.40	3.00e-158	551.00
IUUC-Yli-134342	Yarrowia lipolytica	30.04	7.00e-45	174.00
IUUC-Zma-135021	Zea mays	32.58	4.00e-37	149.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence