iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088002

Ensembl Protein ID

ENSOGAP00000017416.1

UniProt Accession

H0XMS5; H0XMS5_OTOGA

Genbank Protein ID

ENSOGAP00000017416

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03058431

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000026263.1	ENSOGAT00000029032.1	ENSOGAP00000017416.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.40e-20	71.8	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.00e-09	35.1	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaasS++F+a+f+++l+es+  ++v+++d + pev++ ll+F Y++++ +ne
   Q: 46   TDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLRESR-DDTVNFQDnLHPEVLELLLDFAYSSRIAINE 114
           7*************************************.*******99*****************99987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclg++ ++d+++c++L+++  +++l hF+
   Q: 146  PSNCLGMMLLSDAHQCRRLYEFSWRMCLVHFE 177
           89*****************************5 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MSVSVHETRK SRSSTGSMNV TLFHKASHPD CVLAHLNTLR KHRMFTDVTL WAGDRAFPCH 60
RAVLAASSRY FEAMFSHGLR ESRDDTVNFQ DNLHPEVLEL LLDFAYSSRI AINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGTCA GCGTCCACGA GACCCGCAAG TCGCGGAGCA GCACCGGCTC CATGAACGTC 60
ACGCTCTTCC ACAAGGCTTC GCACCCCGAC TGCGTGCTAG CGCACCTCAA CACACTGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	97.11	0.00e+00	1180.00
IUUC-Apl-003543	Anas platyrhynchos	89.32	0.00e+00	1062.00
IUUC-Aca-004729	Anolis carolinensis	86.76	0.00e+00	1045.00
IUUC-Ame-011020	Astyanax mexicanus	85.23	0.00e+00	1010.00
IUUC-Bta-012955	Bos taurus	96.26	0.00e+00	1174.00
IUUC-Cja-018839	Callithrix jacchus	97.28	0.00e+00	1175.00
IUUC-Cfa-020224	Canis familiaris	97.79	0.00e+00	1187.00
IUUC-Cpo-021593	Cavia porcellus	93.72	0.00e+00	1118.00
IUUC-Csa-023276	Chlorocebus sabaeus	97.96	0.00e+00	1182.00
IUUC-Dre-028053	Danio rerio	85.06	0.00e+00	1001.00
IUUC-Dno-029287	Dasypus novemcinctus	95.08	0.00e+00	1164.00
IUUC-Dor-030908	Dipodomys ordii	88.79	0.00e+00	1061.00
IUUC-Fca-035897	Felis catus	97.62	0.00e+00	1182.00
IUUC-Fal-037036	Ficedula albicollis	89.30	0.00e+00	1066.00
IUUC-Gmo-039345	Gadus morhua	84.89	0.00e+00	978.00
IUUC-Gga-040404	Gallus gallus	89.30	0.00e+00	1068.00
IUUC-Gac-042447	Gasterosteus aculeatus	84.38	0.00e+00	993.00
IUUC-Ggo-045060	Gorilla gorilla	97.79	0.00e+00	1181.00
IUUC-Hsa-046494	Homo sapiens	97.79	0.00e+00	1181.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	97.45	0.00e+00	1182.00
IUUC-Lch-050211	Latimeria chalumnae	86.22	0.00e+00	1025.00
IUUC-Loc-052578	Lepisosteus oculatus	85.06	0.00e+00	1016.00
IUUC-Lma-053168	Leptosphaeria maculans	29.79	7.00e-05	41.60
IUUC-Laf-053498	Loxodonta africana	95.76	0.00e+00	1118.00
IUUC-Mcc-055033	Macaca mulatta	97.79	0.00e+00	1181.00
IUUC-Meu-056893	Macropus eugenii	92.02	0.00e+00	1123.00
IUUC-Mga-060025	Meleagris gallopavo	89.30	0.00e+00	1068.00
IUUC-Mmr-060658	Microcebus murinus	97.11	0.00e+00	1178.00
IUUC-Mdo-062667	Monodelphis domestica	92.19	0.00e+00	1125.00
IUUC-Mmu-063125	Mus musculus	94.40	0.00e+00	1134.00
IUUC-Mpu-066209	Mustela putorius furo	97.28	0.00e+00	1181.00
IUUC-Mlu-068237	Myotis lucifugus	93.21	0.00e+00	1107.00
IUUC-Nle-069454	Nomascus leucogenys	97.77	0.00e+00	1168.00
IUUC-Ont-072138	Oreochromis niloticus	84.55	0.00e+00	983.00
IUUC-Oan-073320	Ornithorhynchus anatinus	86.93	0.00e+00	1068.00
IUUC-Ocu-073765	Oryctolagus cuniculus	89.98	0.00e+00	1078.00
IUUC-Oar-089481	Ovis aries	95.59	0.00e+00	1169.00
IUUC-Ptr-091200	Pan troglodytes	97.62	0.00e+00	1177.00
IUUC-Psi-093884	Pelodiscus sinensis	88.96	0.00e+00	1056.00
IUUC-Pno-095143	Phaeosphaeria nodorum	27.24	1.00e-14	73.90
IUUC-Pab-098588	Pongo abelii	86.93	0.00e+00	1013.00
IUUC-Pva-102321	Pteropus vampyrus	96.43	0.00e+00	1172.00
IUUC-Rno-104835	Rattus norvegicus	93.89	0.00e+00	1130.00
IUUC-Sha-107528	Sarcophilus harrisii	91.85	0.00e+00	1122.00
IUUC-Ssc-116161	Sus scrofa	98.13	0.00e+00	1206.00
IUUC-Tgu-116569	Taeniopygia guttata	89.13	0.00e+00	1064.00
IUUC-Tni-120525	Tetraodon nigroviridis	75.97	0.00e+00	862.00
IUUC-Ttr-129297	Tursiops truncatus	97.28	0.00e+00	1182.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence