iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022037

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02045368

Gene Name

RABGEF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000015358.3	ENSCPOT00000015508.2	ENSCPOP00000013844.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/ZnF_A20	9.00e-19	67.1	13	47

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/ZnF_A20

   S: 1    dpskllCkkgCgfYGnpetngyCSkCyreelrrrr 35
           d+s+llCkkgCg+YGnp+++g+CSkC+ree++++r
   Q: 13   DQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKAR 47
           79*******************************86 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MSLKSERRGI HVDQSELLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ IQEDWELAER 60
LQREEEEAFA SSQSSQGAQS LTFSKFEEKK TNEKTRKVTT VKKFFSASSR VGSKKEIQEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCCTTA AATCTGAACG CCGAGGAATT CATGTGGATC AGTCGGAGCT CCTGTGCAAG 60
AAAGGATGTG GTTACTACGG CAACCCTGCT TGGCAGGGCT TCTGCTCCAA GTGCTGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003123--VPS9
IPR002653--Znf_A20

PROSITE

PS51205--VPS9
PS51036--ZF_A20

Pfam

PF02204--VPS9
PF01754--zf-A20

SMART

SM00167--VPS9
SM00259--ZnF_A20

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005730--C:nucleolus
GO:0003677--F:DNA binding
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0050728--P:negative regulation of inflammatory response
GO:1900165--P:negative regulation of interleukin-6 secretion
GO:1900235--P:negative regulation of Kit signaling pathway
GO:0002686--P:negative regulation of leukocyte migration
GO:0043305--P:negative regulation of mast cell degranulation
GO:0001933--P:negative regulation of protein phosphorylation
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0048261--P:negative regulation of receptor-mediated endocytosis
GO:0006612--P:protein targeting to membrane
GO:0060368--P:regulation of Fc receptor mediated stimulatory signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000198	Aegilops tauschii	31.51	1.00e-19	91.30
IUUC-Aml-001771	Ailuropoda melanoleuca	87.26	0.00e+00	741.00
IUUC-Atr-003154	Amborella trichopoda	35.96	4.00e-22	99.00
IUUC-Apl-004018	Anas platyrhynchos	91.26	0.00e+00	838.00
IUUC-Aca-005227	Anolis carolinensis	23.47	4.00e-09	57.00
IUUC-Aly-006138	Arabidopsis lyrata	33.96	5.00e-24	105.00
IUUC-Ath-006929	Arabidopsis thaliana	32.14	9.00e-26	111.00
IUUC-Ago-007776	Ashbya gossypii	30.00	9.00e-24	104.00
IUUC-Acl-008235	Aspergillus clavatus	30.94	4.00e-28	120.00
IUUC-Afl-008570	Aspergillus flavus	31.79	1.00e-30	127.00
IUUC-Afu-008815	Aspergillus fumigatus	30.71	1.00e-28	121.00
IUUC-Ani-009381	Aspergillus nidulans	30.55	8.00e-29	122.00
IUUC-Ang-009615	Aspergillus niger	30.94	7.00e-31	128.00
IUUC-Aor-010195	Aspergillus oryzae	31.13	4.00e-31	129.00
IUUC-Ate-010514	Aspergillus terreus	31.65	1.00e-29	124.00
IUUC-Ame-011365	Astyanax mexicanus	66.73	0.00e+00	672.00
IUUC-Bgr-012102	Blumeria graminis	28.85	2.00e-29	124.00
IUUC-Bta-013124	Bos taurus	96.33	0.00e+00	876.00
IUUC-Bci-013943	Botrytis cinerea	30.29	3.00e-29	123.00
IUUC-Bdi-014539	Brachypodium distachyon	33.94	1.00e-25	110.00
IUUC-Bol-016580	Brassica oleracea	34.23	3.00e-29	122.00
IUUC-Bra-017843	Brassica rapa	33.78	2.00e-29	123.00
IUUC-Cel-018199	Caenorhabditis elegans	33.75	5.00e-60	225.00
IUUC-Cja-019941	Callithrix jacchus	96.13	0.00e+00	872.00
IUUC-Cfa-020845	Canis familiaris	95.87	0.00e+00	796.00
IUUC-Cre-022696	Chlamydomonas reinhardtii	31.82	3.00e-21	96.30
IUUC-Csa-023272	Chlorocebus sabaeus	95.32	0.00e+00	867.00
IUUC-Cho-025076	Choloepus hoffmanni	84.32	0.00e+00	726.00
IUUC-Cin-025400	Ciona intestinalis	44.71	4.00e-116	411.00
IUUC-Csv-025941	Ciona savignyi	38.52	4.00e-87	315.00
IUUC-Cgl-026725	Colletotrichum gloeosporioides	29.20	5.00e-27	116.00
IUUC-Cne-027057	Cryptococcus neoformans	31.76	9.00e-35	142.00
IUUC-Dre-028484	Danio rerio	71.74	0.00e+00	676.00
IUUC-Dno-028906	Dasypus novemcinctus	96.14	0.00e+00	857.00
IUUC-Dor-030124	Dipodomys ordii	86.53	0.00e+00	753.00
IUUC-Dse-031437	Dothistroma septosporum	27.96	4.00e-26	113.00
IUUC-Dme-031696	Drosophila melanogaster	33.13	7.00e-69	254.00
IUUC-Ete-032573	Echinops telfairi	92.53	0.00e+00	716.00
IUUC-Eca-033711	Equus caballus	96.74	0.00e+00	879.00
IUUC-Eeu-034459	Erinaceus europaeus	73.30	1.00e-78	288.00
IUUC-Fca-035447	Felis catus	93.69	0.00e+00	884.00
IUUC-Fal-036605	Ficedula albicollis	87.68	0.00e+00	778.00
IUUC-Fox-037967	Fusarium oxysporum	26.71	2.00e-18	87.80
IUUC-Fso-038110	Fusarium solani	28.98	5.00e-28	119.00
IUUC-Gmo-038785	Gadus morhua	66.21	0.00e+00	670.00
IUUC-Ggr-039760	Gaeumannomyces graminis	30.07	7.00e-27	115.00
IUUC-Gga-040584	Gallus gallus	91.87	0.00e+00	841.00
IUUC-Gac-042469	Gasterosteus aculeatus	63.98	7.00e-167	580.00
IUUC-Gma-044237	Glycine max	37.99	4.00e-27	115.00
IUUC-Ggo-044498	Gorilla gorilla	82.32	0.00e+00	721.00
IUUC-Hsa-046625	Homo sapiens	96.13	0.00e+00	872.00
IUUC-Hvu-047155	Hordeum vulgare	37.22	2.00e-25	110.00
IUUC-Itr-048753	Ictidomys tridecemlineatus	96.54	0.00e+00	880.00
IUUC-Kpa-049160	Komagataella pastoris	28.81	9.00e-25	108.00
IUUC-Lch-050529	Latimeria chalumnae	77.76	0.00e+00	847.00
IUUC-Lpe-051024	Leersia perrieri	33.94	7.00e-28	118.00
IUUC-Loc-052644	Lepisosteus oculatus	69.65	0.00e+00	665.00
IUUC-Lma-053102	Leptosphaeria maculans	30.42	1.00e-27	118.00
IUUC-Laf-054337	Loxodonta africana	94.50	0.00e+00	863.00
IUUC-Mcc-055659	Macaca mulatta	95.59	8.00e-177	612.00
IUUC-Meu-056084	Macropus eugenii	75.11	1.00e-93	336.00
IUUC-Mor-057255	Magnaporthe oryzae	29.35	6.00e-27	115.00
IUUC-Mpo-057454	Magnaporthe poae	30.07	1.00e-28	121.00
IUUC-Mtr-058098	Medicago truncatula	33.18	3.00e-28	119.00
IUUC-Mla-059068	Melampsora laricipopulina	29.64	2.00e-31	130.00
IUUC-Mga-059624	Meleagris gallopavo	78.34	0.00e+00	832.00
IUUC-Mvi-060282	Microbotryum violaceum	28.00	2.00e-25	111.00
IUUC-Mmr-061142	Microcebus murinus	96.74	0.00e+00	885.00
IUUC-Mdo-062289	Monodelphis domestica	93.08	0.00e+00	899.00
IUUC-Mmu-063961	Mus musculus	96.13	0.00e+00	870.00
IUUC-Mac-065188	Musa acuminata	32.40	1.00e-21	97.40
IUUC-Mpu-066291	Mustela putorius furo	96.54	0.00e+00	872.00
IUUC-Mlu-067431	Myotis lucifugus	91.67	0.00e+00	827.00
IUUC-Nfi-068422	Neosartorya fischeri	30.10	5.00e-29	122.00
IUUC-Ncr-068843	Neurospora crassa	30.04	2.00e-28	121.00
IUUC-Nle-069079	Nomascus leucogenys	95.52	0.00e+00	868.00
IUUC-Opr-070790	Ochotona princeps	93.52	2.00e-55	209.00
IUUC-Ont-071789	Oreochromis niloticus	68.55	2.00e-177	615.00
IUUC-Oan-072946	Ornithorhynchus anatinus	89.66	0.00e+00	808.00
IUUC-Ocu-073816	Oryctolagus cuniculus	96.75	0.00e+00	872.00
IUUC-Oba-075738	Oryza barthii	29.22	2.00e-16	80.50
IUUC-Obr-076355	Oryza brachyantha	36.81	2.00e-26	113.00
IUUC-Ogl-077592	Oryza glaberrima	29.13	5.00e-28	118.00
IUUC-Ogu-078197	Oryza glumaepatula	29.13	7.00e-28	117.00
IUUC-Oin-079629	Oryza indica	29.13	5.00e-28	118.00
IUUC-Olo-080317	Oryza longistaminata	29.13	9.00e-28	117.00
IUUC-Ome-081589	Oryza meridionalis	36.11	4.00e-25	109.00
IUUC-Oni-082700	Oryza nivara	29.22	1.00e-16	80.90
IUUC-Opu-083923	Oryza punctata	34.97	5.00e-22	98.20
IUUC-Oru-084318	Oryza rufipogon	29.22	1.00e-16	80.90
IUUC-Osa-086246	Oryza sativa	40.68	4.00e-07	45.80
IUUC-Ola-086730	Oryzias latipes	56.87	4.00e-149	521.00
IUUC-Olu-087719	Ostreococcus lucimarinus	33.90	2.00e-22	100.00
IUUC-Oga-088992	Otolemur garnettii	83.98	0.00e+00	872.00
IUUC-Oar-089789	Ovis aries	96.15	0.00e+00	868.00
IUUC-Ptr-091636	Pan troglodytes	96.13	0.00e+00	872.00
IUUC-Pan-092911	Papio anubis	95.52	0.00e+00	868.00
IUUC-Psi-093194	Pelodiscus sinensis	78.61	0.00e+00	828.00
IUUC-Pma-094212	Petromyzon marinus	48.09	9.00e-113	400.00
IUUC-Pno-094831	Phaeosphaeria nodorum	30.04	4.00e-27	116.00
IUUC-Ppa-095705	Physcomitrella patens	30.71	2.00e-28	120.00
IUUC-Pfo-096694	Poecilia formosa	65.22	2.00e-179	621.00
IUUC-Pab-097706	Pongo abelii	95.93	0.00e+00	870.00
IUUC-Pop-099891	Populus trichocarpa	36.31	9.00e-25	108.00
IUUC-Pca-100879	Procavia capensis	94.37	1.00e-92	333.00
IUUC-Ppe-101334	Prunus persica	31.01	9.00e-26	111.00
IUUC-Pva-103225	Pteropus vampyrus	80.61	0.00e+00	701.00
IUUC-Pgr-103564	Puccinia graminis	30.00	8.00e-31	129.00
IUUC-Ptt-103802	Puccinia triticina	29.57	2.00e-25	110.00
IUUC-Pte-104345	Pyrenophora teres	29.30	9.00e-28	119.00
IUUC-Pyt-104716	Pyrenophora triticirepentis	30.40	1.00e-27	118.00
IUUC-Rno-106101	Rattus norvegicus	95.52	0.00e+00	867.00
IUUC-Sce-106460	Saccharomyces cerevisiae	30.38	5.00e-25	108.00
IUUC-Sha-106919	Sarcophilus harrisii	78.27	0.00e+00	836.00
IUUC-Sja-107880	Schizosaccharomyces japonicus	31.82	4.00e-30	125.00
IUUC-Spo-108087	Schizosaccharomyces pombe	29.34	2.00e-27	117.00
IUUC-Ssl-108614	Sclerotinia sclerotiorum	28.95	5.00e-07	50.10
IUUC-Smo-108740	Selaginella moellendorffii	36.67	3.00e-28	119.00
IUUC-Sit-110678	Setaria italica	33.66	4.00e-25	109.00
IUUC-Sly-111526	Solanum lycopersicum	37.29	5.00e-25	108.00
IUUC-Stu-112494	Solanum tuberosum	37.85	1.00e-25	110.00
IUUC-Sar-112929	Sorex araneus	96.00	1.00e-159	556.00
IUUC-Sbi-114242	Sorghum bicolor	31.87	5.00e-27	115.00
IUUC-Sre-115224	Sporisorium reilianum	31.54	1.00e-29	125.00
IUUC-Ssc-115239	Sus scrofa	96.75	0.00e+00	875.00
IUUC-Tgu-117499	Taeniopygia guttata	89.41	0.00e+00	822.00
IUUC-Tru-118027	Takifugu rubripes	63.87	3.00e-142	498.00
IUUC-Tsy-119462	Tarsius syrichta	96.43	0.00e+00	857.00
IUUC-Tni-120855	Tetraodon nigroviridis	64.34	1.00e-172	599.00
IUUC-Tca-121213	Theobroma cacao	34.92	6.00e-24	105.00
IUUC-Tre-122186	Trichoderma reesei	28.57	6.00e-28	119.00
IUUC-Tvi-122541	Trichoderma virens	28.17	2.00e-28	120.00
IUUC-Tae-123631	Triticum aestivum	33.85	2.00e-26	113.00
IUUC-Tur-126572	Triticum urartu	38.33	1.00e-25	110.00
IUUC-Tme-127023	Tuber melanosporum	32.26	3.00e-31	130.00
IUUC-Tbe-127453	Tupaia belangeri	95.84	0.00e+00	765.00
IUUC-Ttr-128526	Tursiops truncatus	96.33	0.00e+00	875.00
IUUC-Uma-129660	Ustilago maydis	31.91	7.00e-30	126.00
IUUC-Vda-129737	Verticillium dahliae	29.82	8.00e-24	105.00
IUUC-Vpa-130505	Vicugna pacos	89.09	0.00e+00	702.00
IUUC-Vvi-131088	Vitis vinifera	36.52	3.00e-23	102.00
IUUC-Xtr-132799	Xenopus tropicalis	80.69	0.00e+00	742.00
IUUC-Xma-133345	Xiphophorus maculatus	65.82	2.00e-175	608.00
IUUC-Yli-134416	Yarrowia lipolytica	32.10	6.00e-32	132.00
IUUC-Zma-134750	Zea mays	35.56	2.00e-24	107.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence