iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049316

Ensembl Protein ID

CAY67098

UniProt Accession

C4QV28; C4QV28_KOMPG

Genbank Protein ID

CAY67098.1

Protein Name

Ubiquitin-conjugating enzyme (E2) and catalytic subunit of SCF ubiquitin-protein ligase complex

Genbank Nucleotide ID

FN392319

Gene Name

PAS_chr1-3_0048

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr1-3_0048	CAY67098	CAY67098

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.00e-41	139.1	19	158

Active Site

Position(s)	Description	Evidence
92	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 8    elekdppegisakpvdesdltewevlilG.pedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........eeekWspal 96
           +  k+ ++ ++++++d+ +++ w++ ++  +++++Y+gg+Fk +++fp d+Pf+PP+++f+  i+hPnvy++G++C+sil+           ++e+Wspa+
   Q: 19   D-PKKGVPCFHIELEDD-NIFLWNIGVMVlNKESIYHGGYFKGQMKFPLDFPFSPPTFRFTPAIYHPNVYRDGRLCISILHqgggdpttdepDSETWSPAQ 117
           3.355567788899998.9******99986899***********************************************8899999999999******** PP
   S: 97   svesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           +vesvl+si+sll++pn++sp+n++aa  ++kn e+yk++v
   Q: 118  TVESVLISIVSLLEDPNISSPANVDAAVDYRKNTEKYKERV 158
           **************************************998 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MSNAAAASIL LRQFRELTDP KKGVPCFHIE LEDDNIFLWN IGVMVLNKES IYHGGYFKGQ 60
MKFPLDFPFS PPTFRFTPAI YHPNVYRDGR LCISILHQGG GDPTTDEPDS ETWSPAQTVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCAACG CAGCAGCTGC CTCCATCTTA CTAAGGCAGT TCAGAGAACT CACAGACCCC 60
AAGAAGGGCG TTCCATGCTT CCATATTGAA TTGGAGGACG ATAACATCTT CCTCTGGAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

ppa:PAS_chr1-3_0048

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007877	Ashbya gossypii	78.05	1.00e-79	286.00
IUUC-Acl-008052	Aspergillus clavatus	52.22	6.00e-47	178.00
IUUC-Afl-008620	Aspergillus flavus	52.36	3.00e-51	192.00
IUUC-Afu-009004	Aspergillus fumigatus	56.47	2.00e-47	179.00
IUUC-Ani-009262	Aspergillus nidulans	50.90	5.00e-51	191.00
IUUC-Ang-009716	Aspergillus niger	55.17	2.00e-41	160.00
IUUC-Aor-009930	Aspergillus oryzae	52.36	3.00e-51	192.00
IUUC-Ate-010563	Aspergillus terreus	52.04	2.00e-51	193.00
IUUC-Bgr-012246	Blumeria graminis	47.40	4.00e-44	168.00
IUUC-Bci-013915	Botrytis cinerea	48.61	8.00e-47	177.00
IUUC-Cel-018460	Caenorhabditis elegans	42.69	4.00e-39	152.00
IUUC-Cin-025257	Ciona intestinalis	43.09	6.00e-40	154.00
IUUC-Csv-025954	Ciona savignyi	45.26	4.00e-40	155.00
IUUC-Cgl-026751	Colletotrichum gloeosporioides	48.59	5.00e-40	155.00
IUUC-Dse-031160	Dothistroma septosporum	49.16	7.00e-42	161.00
IUUC-Fox-037794	Fusarium oxysporum	47.37	1.00e-38	150.00
IUUC-Fso-038169	Fusarium solani	44.79	8.00e-37	144.00
IUUC-Ggr-040103	Gaeumannomyces graminis	48.85	8.00e-41	157.00
IUUC-Lma-052988	Leptosphaeria maculans	48.08	4.00e-50	188.00
IUUC-Mor-056910	Magnaporthe oryzae	50.29	3.00e-39	152.00
IUUC-Mpo-057346	Magnaporthe poae	45.77	2.00e-41	159.00
IUUC-Nfi-068322	Neosartorya fischeri	51.79	3.00e-49	186.00
IUUC-Ncr-068676	Neurospora crassa	45.85	3.00e-40	155.00
IUUC-Opr-070826	Ochotona princeps	44.59	2.00e-32	130.00
IUUC-Ptr-090916	Pan troglodytes	42.51	4.00e-33	132.00
IUUC-Pno-094950	Phaeosphaeria nodorum	48.76	5.00e-52	195.00
IUUC-Pte-104143	Pyrenophora teres	50.27	1.00e-51	194.00
IUUC-Pyt-104604	Pyrenophora triticirepentis	50.27	2.00e-51	193.00
IUUC-Sce-106444	Saccharomyces cerevisiae	72.25	1.00e-91	327.00
IUUC-Ssl-108409	Sclerotinia sclerotiorum	50.24	3.00e-50	189.00
IUUC-Tvi-122621	Trichoderma virens	41.84	7.00e-38	148.00
IUUC-Tme-127042	Tuber melanosporum	46.83	5.00e-44	168.00
IUUC-Vda-130006	Verticillium dahliae	50.29	1.00e-39	154.00
IUUC-Yli-134354	Yarrowia lipolytica	62.25	1.00e-64	236.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence