iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026903

Ensembl Protein ID

AAW43544

UniProt Accession

Q5KGN1; Q55S80; Q5KGN1_CRYNJ

Genbank Protein ID

AAW43544.1

Protein Name

Ubiquitin conjugating enzyme, putative

Genbank Nucleotide ID

AE017345

Gene Name

CNE03030

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNE03030	AAW43544	AAW43544

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.30e-43	146.5	17	167

Active Site

Position(s)	Description	Evidence
99	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdpp.egisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk...........ee 89
           Rl+ke+ +l++dp  ++i+a+pv+e+++ ewe+li Gpe+tpYeggvF +++ fp+dYP++P +++f  +++hPn+y+nG vC+sil+            +
   Q: 17   RLMKEYRDLTADPLqDTITAGPVSEDNMLEWEALIQGPEGTPYEGGVFAARLVFPSDYPLNPFTMTFDPPLLHPNIYPNGLVCISILHppgddpmqyesAS 117
           9*********99974789*********************************************************************88999999999999 PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           e+Wsp++ v+svlls+ s+laepn+es+++ e ++l+++n+ e++++vre
   Q: 118  ERWSPVQGVRSVLLSVLSMLAEPNIESGADIECCKLYRDNKPEFERRVRE 167
           ***********************************************985 PP

Organism

Cryptococcus neoformans

Protein Sequence
(Fasta)

MFGNNNSRSQ SSTATRRLMK EYRDLTADPL QDTITAGPVS EDNMLEWEAL IQGPEGTPYE 60
GGVFAARLVF PSDYPLNPFT MTFDPPLLHP NIYPNGLVCI SILHPPGDDP MQYESASERW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTGGCA ACAACAACTC TCGATCACAA TCTTCCACGG CTACCCGAAG GTATGGTATC 60
GGTAGAGTTT TAGACAGACA AAAAAGCGTC CCGCTGATCT TGCTTCCTCG AAGACTGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0000837--C:Doa10p ubiquitin ligase complex
GO:0000839--C:Hrd1p ubiquitin ligase ERAD-L complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006333--P:chromatin assembly or disassembly
GO:0030466--P:chromatin silencing at silent mating-type cassette
GO:0031505--P:fungal-type cell wall organization
GO:0010620--P:negative regulation of transcription by transcription factor catabolism
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cne:CNE03030

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002172	Ailuropoda melanoleuca	56.33	2.00e-48	182.00
IUUC-Apl-003761	Anas platyrhynchos	55.15	2.00e-49	186.00
IUUC-Aca-005062	Anolis carolinensis	56.36	1.00e-50	190.00
IUUC-Ago-007853	Ashbya gossypii	63.03	2.00e-59	219.00
IUUC-Acl-008080	Aspergillus clavatus	62.65	5.00e-60	221.00
IUUC-Afl-008478	Aspergillus flavus	60.24	1.00e-58	216.00
IUUC-Afu-009051	Aspergillus fumigatus	63.25	2.00e-60	222.00
IUUC-Ani-009271	Aspergillus nidulans	66.21	5.00e-53	197.00
IUUC-Ang-009748	Aspergillus niger	62.05	2.00e-59	219.00
IUUC-Aor-010228	Aspergillus oryzae	59.64	2.00e-58	216.00
IUUC-Ate-010293	Aspergillus terreus	62.65	4.00e-60	221.00
IUUC-Ame-011698	Astyanax mexicanus	58.79	7.00e-55	204.00
IUUC-Bgr-012226	Blumeria graminis	62.42	7.00e-58	214.00
IUUC-Bta-013277	Bos taurus	58.54	1.00e-39	152.00
IUUC-Bci-013676	Botrytis cinerea	61.82	9.00e-59	217.00
IUUC-Cel-018676	Caenorhabditis elegans	52.47	4.00e-47	178.00
IUUC-Cja-019767	Callithrix jacchus	56.97	2.00e-52	196.00
IUUC-Cfa-020047	Canis familiaris	57.58	1.00e-52	196.00
IUUC-Cpo-021507	Cavia porcellus	56.97	3.00e-52	195.00
IUUC-Csa-023745	Chlorocebus sabaeus	53.33	2.00e-48	182.00
IUUC-Cin-025310	Ciona intestinalis	55.83	1.00e-53	200.00
IUUC-Csv-025961	Ciona savignyi	54.60	1.00e-52	196.00
IUUC-Cgl-026553	Colletotrichum gloeosporioides	64.63	2.00e-60	222.00
IUUC-Dre-027900	Danio rerio	58.79	8.00e-55	203.00
IUUC-Dno-029688	Dasypus novemcinctus	56.49	1.00e-47	180.00
IUUC-Dor-030686	Dipodomys ordii	44.71	8.00e-35	138.00
IUUC-Dse-031253	Dothistroma septosporum	57.58	2.00e-55	206.00
IUUC-Dme-031849	Drosophila melanogaster	58.79	5.00e-55	204.00
IUUC-Ete-033010	Echinops telfairi	56.97	7.00e-51	191.00
IUUC-Eca-033294	Equus caballus	55.70	2.00e-48	182.00
IUUC-Eeu-034947	Erinaceus europaeus	50.39	4.00e-28	114.00
IUUC-Fca-036442	Felis catus	59.12	3.00e-45	171.00
IUUC-Fal-037188	Ficedula albicollis	55.84	2.00e-47	179.00
IUUC-Fox-037762	Fusarium oxysporum	62.42	7.00e-60	220.00
IUUC-Fso-038181	Fusarium solani	61.82	3.00e-59	218.00
IUUC-Gmo-038663	Gadus morhua	57.58	4.00e-53	198.00
IUUC-Ggr-039808	Gaeumannomyces graminis	62.20	8.00e-59	217.00
IUUC-Gga-040355	Gallus gallus	56.36	4.00e-52	194.00
IUUC-Gac-041847	Gasterosteus aculeatus	57.58	1.00e-53	200.00
IUUC-Ggo-045202	Gorilla gorilla	56.97	2.00e-52	196.00
IUUC-Hsa-046369	Homo sapiens	56.97	2.00e-52	196.00
IUUC-Itr-048349	Ictidomys tridecemlineatus	58.18	4.00e-53	198.00
IUUC-Kpa-049317	Komagataella pastoris	60.61	7.00e-59	217.00
IUUC-Lch-049596	Latimeria chalumnae	56.13	2.00e-48	182.00
IUUC-Loc-052346	Lepisosteus oculatus	60.16	5.00e-41	157.00
IUUC-Lma-053126	Leptosphaeria maculans	59.09	6.00e-46	174.00
IUUC-Laf-054560	Loxodonta africana	53.61	6.00e-49	184.00
IUUC-Mcc-055172	Macaca mulatta	56.97	2.00e-52	196.00
IUUC-Meu-056891	Macropus eugenii	56.33	2.00e-48	182.00
IUUC-Mor-057260	Magnaporthe oryzae	62.80	9.00e-60	220.00
IUUC-Mpo-057468	Magnaporthe poae	61.59	3.00e-58	215.00
IUUC-Mla-059084	Melampsora laricipopulina	62.92	3.00e-64	235.00
IUUC-Mga-059939	Meleagris gallopavo	52.73	2.00e-48	182.00
IUUC-Mvi-060514	Microbotryum violaceum	61.27	3.00e-61	225.00
IUUC-Mmr-061029	Microcebus murinus	55.15	3.00e-50	188.00
IUUC-Mdo-061820	Monodelphis domestica	57.58	5.00e-53	197.00
IUUC-Mmu-063123	Mus musculus	56.97	2.00e-52	196.00
IUUC-Mpu-065866	Mustela putorius furo	56.17	8.00e-49	184.00
IUUC-Mlu-067220	Myotis lucifugus	55.70	4.00e-48	181.00
IUUC-Nfi-068395	Neosartorya fischeri	63.25	2.00e-60	222.00
IUUC-Ncr-068623	Neurospora crassa	61.59	6.00e-58	214.00
IUUC-Nle-070007	Nomascus leucogenys	56.97	2.00e-52	196.00
IUUC-Opr-071095	Ochotona princeps	64.04	2.00e-37	145.00
IUUC-Ont-071736	Oreochromis niloticus	57.58	9.00e-54	200.00
IUUC-Oan-073475	Ornithorhynchus anatinus	55.06	1.00e-47	180.00
IUUC-Ocu-074820	Oryctolagus cuniculus	54.60	7.00e-49	184.00
IUUC-Ola-087571	Oryzias latipes	57.58	2.00e-53	199.00
IUUC-Oar-089706	Ovis aries	56.97	2.00e-52	196.00
IUUC-Ptr-090798	Pan troglodytes	56.97	2.00e-52	196.00
IUUC-Pan-091967	Papio anubis	56.97	2.00e-52	196.00
IUUC-Psi-093524	Pelodiscus sinensis	57.89	5.00e-48	181.00
IUUC-Pma-094602	Petromyzon marinus	61.15	1.00e-48	182.00
IUUC-Pno-094979	Phaeosphaeria nodorum	59.39	4.00e-58	214.00
IUUC-Pfo-097330	Poecilia formosa	57.58	2.00e-53	199.00
IUUC-Pab-098225	Pongo abelii	56.36	8.00e-52	194.00
IUUC-Pca-101040	Procavia capensis	56.49	1.00e-47	180.00
IUUC-Pva-102507	Pteropus vampyrus	49.37	8.00e-39	150.00
IUUC-Pgr-103674	Puccinia graminis	59.32	4.00e-61	224.00
IUUC-Ptt-103840	Puccinia triticina	58.76	6.00e-61	224.00
IUUC-Pte-104389	Pyrenophora teres	60.61	6.00e-59	217.00
IUUC-Pyt-104703	Pyrenophora triticirepentis	61.21	4.00e-59	218.00
IUUC-Rno-105228	Rattus norvegicus	56.97	2.00e-52	196.00
IUUC-Sce-106233	Saccharomyces cerevisiae	61.21	9.00e-56	207.00
IUUC-Sha-107274	Sarcophilus harrisii	54.76	1.00e-48	183.00
IUUC-Sja-107937	Schizosaccharomyces japonicus	59.15	2.00e-55	206.00
IUUC-Spo-108269	Schizosaccharomyces pombe	58.54	5.00e-55	204.00
IUUC-Ssl-108636	Sclerotinia sclerotiorum	62.42	2.00e-59	219.00
IUUC-Sar-112992	Sorex araneus	44.58	4.00e-33	132.00
IUUC-Sre-114952	Sporisorium reilianum	62.35	1.00e-63	233.00
IUUC-Ssc-115365	Sus scrofa	55.77	4.00e-48	181.00
IUUC-Tgu-116816	Taeniopygia guttata	56.36	4.00e-52	194.00
IUUC-Tni-120278	Tetraodon nigroviridis	54.55	7.00e-52	194.00
IUUC-Tre-122131	Trichoderma reesei	63.41	3.00e-59	218.00
IUUC-Tvi-122669	Trichoderma virens	63.41	9.00e-60	220.00
IUUC-Tme-127052	Tuber melanosporum	57.93	2.00e-55	206.00
IUUC-Tbe-127792	Tupaia belangeri	56.97	2.00e-52	196.00
IUUC-Ttr-128619	Tursiops truncatus	61.16	8.00e-38	146.00
IUUC-Uma-129587	Ustilago maydis	62.94	2.00e-64	236.00
IUUC-Vda-129914	Verticillium dahliae	63.41	4.00e-60	221.00
IUUC-Xtr-132450	Xenopus tropicalis	56.97	6.00e-53	197.00
IUUC-Xma-133016	Xiphophorus maculatus	57.58	2.00e-53	199.00
IUUC-Yli-134379	Yarrowia lipolytica	59.17	2.00e-55	205.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence