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Tag Content
UUCD2 ID IUUC-Mcc-055584
UUCD1 version UUC-MaM-01096
Ensembl Protein ID ENSMMUP00000011698.2
UniProt Accession F7DHM3; F7DHM3_MACMU
Genbank Protein ID AFE66802.1; EHH23516.1
Protein Name Ubiquitin carboxyl-terminal hydrolase 2 isoform a
Genbank Nucleotide ID JSUE03013539; CM001266
Gene Name USP2; EGK_06991
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000008921.3 ENSMMUT00000012473.3 ENSMMUP00000011697.3
ENSMMUG00000008921.3 ENSMMUT00000060132.1 ENSMMUP00000054755.1
ENSMMUG00000008921.3 ENSMMUT00000012474.3 ENSMMUP00000011698.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.60e-98 331.2 268 597
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           Gl+NlgNtC+mNS+LQcLsn++elr+++l+  + ++l+++  ++ +++l+++++kl++ +w +s + +vsp+e++++++++a++f gy+
   Q: 268  GLRNLGNTCFMNSILQCLSNTRELRDYCLQrLYMRDLHHS--SNAHTALMEEFAKLIQTIWtSSPNDVVSPSEFKTQIQRYAPRFVGYN 354
           9*****************************7788888877..6799***************889999********************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqDaqEfl+flld+l++e+++ +  pk++ e+ d+  l+d+      ++k  ++++s i dlF gqlks+++c +c+  s+ ++pf+dl
   Q: 355  QQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENLDH--LPDDekgrqMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDL 441
           *******************9944444444444442..2222335559****************************************** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
           slp+ ++    + +l dc++ ftke+ l+g++k  c +c++++++ kk++++++P++L+lhLkRf  se++ + +k+++ v+fpl+ Ld
   Q: 442  SLPIAKRGYP-EVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRF--SESRIRTSKLTTFVNFPLRdLD 527
           ******9976.779***************************************************..88899***************** PP
   S: 261  lspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           l++f +++++    +  Y+L+av +HsG++ +GHY+ay+++  +g+W +f+Ds+Vt+++ ++v +   s+aY+lfY+
   Q: 528  LREFASENTN----HAVYNLYAVSNHSGTTMGGHYTAYCRSpGTGEWHTFNDSSVTPMSSSQVRT---SDAYLLFYE 597
           ******9553....78*************************44555*******************...********8 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MSQLSSTLKR YTESARYTDA HYSKSGYGAY TPSSYGANLA ASLLEKEKFG FKPVPASSFL 60
TRPRTYGPSS ILDYDRGRPL LRPNITGGGK RAESQTRGTE RPSGSGLSGG SGFPYGVSNN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055584|DUB,USP|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGTGACGCGA GACGCGGGGG TGTGGCTCTG CCGGCCCAGG CGCGATGAGG CGGCTGCCCG 60
CTGGGTGGCG CCGATTTCCC GGGGAGGTCC CTTCTGGGAC CCCGGCGGAG GTGGGAGAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055584|DUB,USP|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0005938--C:cell cortex
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0032922--P:circadian regulation of gene expression
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0045475--P:locomotor rhythm
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0016579--P:protein deubiquitination
GO:0050821--P:protein stabilization
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG mcc:705191
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001988 Ailuropoda melanoleuca 92.57 0.00e+00 1071.00
IUUC-Aca-005132 Anolis carolinensis 59.49 0.00e+00 670.00
IUUC-Ame-011102 Astyanax mexicanus 74.93 4.00e-145 507.00
IUUC-Bta-012529 Bos taurus 90.43 0.00e+00 1007.00
IUUC-Bra-016678 Brassica rapa 35.76 4.00e-47 182.00
IUUC-Cja-019016 Callithrix jacchus 93.11 0.00e+00 1078.00
IUUC-Cfa-020714 Canis familiaris 92.74 0.00e+00 1101.00
IUUC-Cpo-021727 Cavia porcellus 88.28 0.00e+00 1010.00
IUUC-Csa-023071 Chlorocebus sabaeus 100.00 0.00e+00 694.00
IUUC-Cin-025797 Ciona intestinalis 50.43 5.00e-95 340.00
IUUC-Csv-026132 Ciona savignyi 50.43 3.00e-97 349.00
IUUC-Dre-027872 Danio rerio 81.23 7.00e-163 566.00
IUUC-Dno-029329 Dasypus novemcinctus 90.43 0.00e+00 1039.00
IUUC-Dor-030574 Dipodomys ordii 90.76 0.00e+00 1030.00
IUUC-Dme-032208 Drosophila melanogaster 46.31 7.00e-82 298.00
IUUC-Ete-032725 Echinops telfairi 80.15 2.00e-171 595.00
IUUC-Eca-033361 Equus caballus 94.22 0.00e+00 1092.00
IUUC-Eeu-035272 Erinaceus europaeus 77.73 0.00e+00 693.00
IUUC-Fca-036497 Felis catus 93.40 0.00e+00 1084.00
IUUC-Fal-036766 Ficedula albicollis 63.73 0.00e+00 681.00
IUUC-Gmo-039129 Gadus morhua 61.39 3.00e-123 434.00
IUUC-Gga-040889 Gallus gallus 83.72 3.00e-147 514.00
IUUC-Gac-042475 Gasterosteus aculeatus 69.83 4.00e-137 481.00
IUUC-Ggo-044814 Gorilla gorilla 93.97 2.00e-180 624.00
IUUC-Hsa-045937 Homo sapiens 96.69 0.00e+00 1097.00
IUUC-Itr-048171 Ictidomys tridecemlineatus 91.83 0.00e+00 1090.00
IUUC-Lch-050527 Latimeria chalumnae 67.74 2.00e-178 618.00
IUUC-Loc-052697 Lepisosteus oculatus 78.86 6.00e-162 564.00
IUUC-Laf-054167 Loxodonta africana 86.68 0.00e+00 1010.00
IUUC-Meu-056542 Macropus eugenii 85.34 0.00e+00 936.00
IUUC-Mga-060020 Meleagris gallopavo 59.26 0.00e+00 633.00
IUUC-Mmr-060989 Microcebus murinus 94.22 0.00e+00 1092.00
IUUC-Mdo-062761 Monodelphis domestica 85.83 0.00e+00 944.00
IUUC-Mmu-063710 Mus musculus 89.01 0.00e+00 1035.00
IUUC-Mpu-066573 Mustela putorius furo 93.40 0.00e+00 1085.00
IUUC-Nle-070013 Nomascus leucogenys 97.05 0.00e+00 1076.00
IUUC-Opr-070907 Ochotona princeps 89.95 0.00e+00 1007.00
IUUC-Ont-071944 Oreochromis niloticus 81.56 1.00e-164 572.00
IUUC-Oan-073105 Ornithorhynchus anatinus 78.47 2.00e-147 514.00
IUUC-Ocu-073941 Oryctolagus cuniculus 91.76 0.00e+00 1055.00
IUUC-Ola-087412 Oryzias latipes 75.00 1.00e-154 540.00
IUUC-Oga-088973 Otolemur garnettii 93.73 0.00e+00 1089.00
IUUC-Oar-089916 Ovis aries 90.76 0.00e+00 1050.00
IUUC-Ptr-090998 Pan troglodytes 97.02 0.00e+00 1104.00
IUUC-Pan-092686 Papio anubis 99.83 0.00e+00 1162.00
IUUC-Psi-093284 Pelodiscus sinensis 71.07 2.00e-123 435.00
IUUC-Pma-094462 Petromyzon marinus 64.71 7.00e-74 269.00
IUUC-Pno-094986 Phaeosphaeria nodorum 32.42 5.00e-40 159.00
IUUC-Pfo-097352 Poecilia formosa 79.21 7.00e-169 587.00
IUUC-Pab-098688 Pongo abelii 90.41 0.00e+00 991.00
IUUC-Pca-100205 Procavia capensis 93.37 0.00e+00 641.00
IUUC-Pva-103188 Pteropus vampyrus 93.23 0.00e+00 1046.00
IUUC-Rno-105853 Rattus norvegicus 89.81 0.00e+00 1078.00
IUUC-Sha-107237 Sarcophilus harrisii 85.17 0.00e+00 935.00
IUUC-Sar-113103 Sorex araneus 91.35 0.00e+00 627.00
IUUC-Ssc-115955 Sus scrofa 92.08 0.00e+00 1063.00
IUUC-Tgu-116894 Taeniopygia guttata 69.72 5.00e-180 623.00
IUUC-Tru-117703 Takifugu rubripes 66.08 3.00e-133 468.00
IUUC-Tsy-118879 Tarsius syrichta 96.64 0.00e+00 845.00
IUUC-Tni-119866 Tetraodon nigroviridis 78.30 3.00e-153 534.00
IUUC-Tbe-127367 Tupaia belangeri 83.49 0.00e+00 653.00
IUUC-Ttr-128773 Tursiops truncatus 88.94 0.00e+00 1042.00
IUUC-Vpa-130402 Vicugna pacos 82.50 0.00e+00 786.00
IUUC-Xtr-132658 Xenopus tropicalis 56.96 4.00e-179 621.00
Created Date 25-Jun-2017

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