iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044759

UUCD1 version

UUC-GoG-01060

Ensembl Protein ID

ENSGGOP00000013825.2

UniProt Accession

G3RE51; G3RE51_GORGO

Protein Name

Uncharacterized protein

Gene Name

ATXN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000014166.2	ENSGGOT00000014223.2	ENSGGOP00000013825.2
ENSGGOG00000014166.2	ENSGGOT00000027578.1	ENSGGOP00000024978.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UIM	4.10e-11	41.9	162	180
UBD/Alpha-Helix/UIM	6.7e-06	16.6	182	198
UBD/Alpha-Helix/UIM	6.2e-05	13.6	265	281

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEeee 19
           +++e+Lq+AlalS+qE ++
   Q: 162  EDEEDLQRALALSRQEIDM 180
           69**************886 PP

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEe 17
           dE+++L++A++lS+q  
   Q: 182  DEEADLRRAIQLSMQGS 198
           7*************976 PP

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEe 17
           +E+++Lq A+++Sl+ +
   Q: 265  SEEDMLQAAVTMSLETV 281
           7*************986 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

QQPSGNMDDS GFFSIQVISN ALKVWGLELI LFNSPEYQRL RIDPINERSF ICNYKEHWFT 60
VRKLGKQWFN LNSLLTGPEL ISDTYLALFL AQLQQEGYSI FVVKGDLPDC EADQLLQMIR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGTCCA TCTTCCACGA GAAAGTGAGT GTCCGCGTTC GGTGGGGAGC TGTCTACCGC 60
GCGGTGGCGG GCGTGGAGCG CGGCATCACC GCCTCTTGGA GGGCTGGGTG GGGCCCGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033865--Ataxin-3
IPR006155--Josephin
IPR003903--UIM_dom

PROSITE

PS50957--JOSEPHIN
PS50330--UIM

Pfam

PF02099--Josephin
PF02809--UIM

SMART

SM01246--Josephin
SM00726--UIM

Gene Ontology

GO:0005829--C:cytosol
GO:0005789--C:endoplasmic reticulum membrane
GO:0005759--C:mitochondrial matrix
GO:0031966--C:mitochondrial membrane
GO:0042405--C:nuclear inclusion body
GO:0005730--C:nucleolus
GO:0005886--C:plasma membrane
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0061578--F:Lys63-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0030036--P:actin cytoskeleton organization
GO:0034605--P:cellular response to heat
GO:0071218--P:cellular response to misfolded protein
GO:0035640--P:exploration behavior
GO:0045104--P:intermediate filament cytoskeleton organization
GO:0000226--P:microtubule cytoskeleton organization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:1904294--P:positive regulation of ERAD pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1904379--P:protein localization to cytosolic proteasome complex involved in ERAD pathway
GO:0010810--P:regulation of cell-substrate adhesion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002015	Ailuropoda melanoleuca	87.67	4.00e-147	513.00
IUUC-Apl-003210	Anas platyrhynchos	72.28	3.00e-114	404.00
IUUC-Aca-005171	Anolis carolinensis	72.22	2.00e-114	405.00
IUUC-Aly-005625	Arabidopsis lyrata	45.71	4.00e-26	111.00
IUUC-Ath-007088	Arabidopsis thaliana	45.71	4.00e-26	111.00
IUUC-Afu-009069	Aspergillus fumigatus	26.89	1.20e-01	29.30
IUUC-Ame-010715	Astyanax mexicanus	63.91	2.00e-87	315.00
IUUC-Bta-013538	Bos taurus	80.58	7.00e-138	483.00
IUUC-Bci-013745	Botrytis cinerea	37.31	1.80e-01	31.20
IUUC-Bdi-015000	Brachypodium distachyon	43.81	8.00e-25	107.00
IUUC-Bol-015894	Brassica oleracea	45.71	7.00e-26	111.00
IUUC-Bra-018020	Brassica rapa	45.71	4.00e-25	109.00
IUUC-Cel-018121	Caenorhabditis elegans	38.19	3.00e-35	141.00
IUUC-Cja-018840	Callithrix jacchus	99.56	8.00e-135	473.00
IUUC-Cfa-021035	Canis familiaris	85.81	2.00e-145	508.00
IUUC-Cpo-021776	Cavia porcellus	80.00	1.00e-139	489.00
IUUC-Csa-023257	Chlorocebus sabaeus	61.15	5.00e-96	343.00
IUUC-Cho-024878	Choloepus hoffmanni	85.71	6.00e-144	503.00
IUUC-Cgl-026754	Colletotrichum gloeosporioides	39.66	2.90e-01	31.20
IUUC-Dre-027506	Danio rerio	68.40	4.00e-81	294.00
IUUC-Dno-029172	Dasypus novemcinctus	85.33	2.00e-144	505.00
IUUC-Dor-030900	Dipodomys ordii	96.43	5.00e-110	390.00
IUUC-Ete-033000	Echinops telfairi	56.71	2.00e-74	271.00
IUUC-Eca-034338	Equus caballus	86.20	4.00e-147	514.00
IUUC-Eeu-034585	Erinaceus europaeus	98.10	3.00e-57	214.00
IUUC-Fca-035441	Felis catus	91.49	9.00e-73	265.00
IUUC-Fal-037525	Ficedula albicollis	69.71	1.00e-102	365.00
IUUC-Gmo-039718	Gadus morhua	67.25	2.00e-76	278.00
IUUC-Gga-040774	Gallus gallus	71.62	9.00e-115	406.00
IUUC-Gac-041671	Gasterosteus aculeatus	67.69	4.00e-81	294.00
IUUC-Gma-042801	Glycine max	42.86	2.00e-24	106.00
IUUC-Hsa-046591	Homo sapiens	83.57	4.00e-134	470.00
IUUC-Hvu-047492	Hordeum vulgare	43.81	6.00e-24	104.00
IUUC-Itr-048851	Ictidomys tridecemlineatus	76.86	1.00e-92	332.00
IUUC-Lch-049519	Latimeria chalumnae	74.69	2.00e-102	364.00
IUUC-Lpe-050819	Leersia perrieri	43.81	1.00e-24	107.00
IUUC-Loc-051816	Lepisosteus oculatus	70.54	8.00e-94	337.00
IUUC-Laf-053784	Loxodonta africana	83.56	5.00e-142	497.00
IUUC-Mcc-055283	Macaca mulatta	88.59	1.00e-151	529.00
IUUC-Meu-056589	Macropus eugenii	76.47	8.00e-120	423.00
IUUC-Mtr-058233	Medicago truncatula	33.01	4.00e-25	108.00
IUUC-Mla-059013	Melampsora laricipopulina	40.30	9.00e-22	97.40
IUUC-Mga-059301	Meleagris gallopavo	70.63	2.00e-116	411.00
IUUC-Mmr-061038	Microcebus murinus	85.48	1.00e-147	515.00
IUUC-Mdo-062927	Monodelphis domestica	79.93	4.00e-114	404.00
IUUC-Mmu-063600	Mus musculus	79.52	2.00e-124	438.00
IUUC-Mpu-065897	Mustela putorius furo	94.07	8.00e-127	446.00
IUUC-Mlu-067543	Myotis lucifugus	94.32	1.00e-127	449.00
IUUC-Nle-069847	Nomascus leucogenys	81.14	1.00e-135	476.00
IUUC-Opr-070550	Ochotona princeps	75.25	3.00e-121	427.00
IUUC-Ont-071723	Oreochromis niloticus	61.83	2.00e-84	305.00
IUUC-Oan-073569	Ornithorhynchus anatinus	73.87	3.00e-121	428.00
IUUC-Ocu-074632	Oryctolagus cuniculus	86.05	4.00e-144	503.00
IUUC-Oba-075288	Oryza barthii	43.81	7.00e-25	107.00
IUUC-Obr-076050	Oryza brachyantha	43.81	1.00e-24	107.00
IUUC-Ogl-077174	Oryza glaberrima	43.81	7.00e-25	107.00
IUUC-Ogu-078006	Oryza glumaepatula	43.81	7.00e-25	107.00
IUUC-Oin-079278	Oryza indica	42.55	1.00e-22	100.00
IUUC-Olo-080941	Oryza longistaminata	43.81	7.00e-25	107.00
IUUC-Ome-081172	Oryza meridionalis	43.81	8.00e-25	107.00
IUUC-Oni-082239	Oryza nivara	43.81	6.00e-25	107.00
IUUC-Opu-083939	Oryza punctata	43.81	1.00e-24	107.00
IUUC-Oru-084393	Oryza rufipogon	43.81	7.00e-25	107.00
IUUC-Osa-086080	Oryza sativa	43.81	7.00e-25	107.00
IUUC-Ola-087566	Oryzias latipes	70.00	1.00e-86	312.00
IUUC-Oga-088617	Otolemur garnettii	74.15	3.00e-93	334.00
IUUC-Oar-090052	Ovis aries	80.91	3.00e-140	491.00
IUUC-Ptr-091435	Pan troglodytes	88.29	2.00e-152	531.00
IUUC-Pan-092777	Papio anubis	96.88	1.00e-106	378.00
IUUC-Psi-093313	Pelodiscus sinensis	87.75	5.00e-96	343.00
IUUC-Pma-094374	Petromyzon marinus	59.61	2.00e-60	226.00
IUUC-Pno-095003	Phaeosphaeria nodorum	34.52	7.40e-02	32.70
IUUC-Ppa-095601	Physcomitrella patens	45.28	2.00e-28	119.00
IUUC-Pfo-097327	Poecilia formosa	65.11	4.00e-85	307.00
IUUC-Pab-098611	Pongo abelii	88.63	3.00e-152	530.00
IUUC-Pca-101022	Procavia capensis	98.28	5.00e-32	131.00
IUUC-Ppe-101545	Prunus persica	42.86	2.00e-23	102.00
IUUC-Pva-102844	Pteropus vampyrus	85.62	2.00e-145	508.00
IUUC-Rno-104896	Rattus norvegicus	79.93	3.00e-130	457.00
IUUC-Sha-107106	Sarcophilus harrisii	80.94	7.00e-134	469.00
IUUC-Sit-110477	Setaria italica	43.81	1.00e-24	106.00
IUUC-Sly-111416	Solanum lycopersicum	39.13	5.00e-18	84.30
IUUC-Stu-112227	Solanum tuberosum	34.13	1.00e-20	92.80
IUUC-Sar-113534	Sorex araneus	77.85	1.00e-123	436.00
IUUC-Sbi-114751	Sorghum bicolor	43.81	2.00e-24	106.00
IUUC-Ssc-115274	Sus scrofa	89.69	2.00e-152	531.00
IUUC-Tgu-117426	Taeniopygia guttata	73.22	5.00e-114	403.00
IUUC-Tru-118059	Takifugu rubripes	70.40	5.00e-82	297.00
IUUC-Tsy-119448	Tarsius syrichta	76.43	3.00e-50	192.00
IUUC-Tni-120681	Tetraodon nigroviridis	88.06	2.00e-34	137.00
IUUC-Tca-121442	Theobroma cacao	33.15	9.00e-25	107.00
IUUC-Tae-123969	Triticum aestivum	43.81	4.00e-24	105.00
IUUC-Tbe-127638	Tupaia belangeri	80.74	8.00e-132	462.00
IUUC-Ttr-129288	Tursiops truncatus	76.53	3.00e-123	434.00
IUUC-Uma-129359	Ustilago maydis	40.00	8.00e-23	101.00
IUUC-Vda-129976	Verticillium dahliae	42.11	8.70e-01	30.00
IUUC-Vpa-130788	Vicugna pacos	84.82	2.00e-147	515.00
IUUC-Vvi-131227	Vitis vinifera	43.81	4.00e-25	108.00
IUUC-Xtr-132147	Xenopus tropicalis	65.00	6.00e-95	340.00
IUUC-Xma-133144	Xiphophorus maculatus	64.68	7.00e-82	296.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence