iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-119993

UUCD1 version

UUC-TeN-00739

Ensembl Protein ID

ENSTNIP00000003613.1

UniProt Accession

H3C5U3; H3C5U3_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000009321.1	ENSTNIT00000012379.1	ENSTNIP00000012188.1
ENSTNIG00000009321.1	ENSTNIT00000000954.1	ENSTNIP00000003613.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.80e-130	434.8	639	968

Active Site

Position(s)	Description	Evidence
938	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           + lk+rl+ ef+gE+gld+gGvtre+++l+ske++np++glf+ys++d++tlq+np+sgl+n++hl++F+f+Gr+ g+a+ +g+lld++
   Q: 639  DLLKARLWLEFEGEKGLDYGGVTREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAV-HGKLLDAF 726
           56899**************************************************************************7.99****** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           + ++fyk++l+k+++l+d+e+vd+e+++sl++i+en   d ++  ldl+f+v+ee++g+t+++eLk+gG +i VtneNk+eY++lv+++
   Q: 727  FIRPFYKMMLHKPITLQDMESVDSEYFNSLMWILEN---DPTD--LDLRFTVDEELFGQTHQHELKSGGTDIIVTNENKKEYIHLVIQW 810
           **********************************99...6666..7999999************************************* PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvT 269
           r+ ++i+ q++af+eGf e+ip +l+++F+e+elell+cG  ++dv+d++++t+yk+gy +++ +iqwFw+++  ++ e r ++LqFvT
   Q: 811  RFVNRIQMQMTAFKEGFFELIPHDLIKIFDENELELLMCGLGDVDVNDWRENTRYKNGYGSNHIVIQWFWKTVLLMDGERRIRLLQFVT 899
           ***************************************************************************************** PP
   S: 270  gssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           g+sr+P++Gfael     p+lf+i+++++ d+lP+++TCfn+L+LP+Y+s e+l+ekL +Aie+++gF+
   Q: 900  GTSRVPMNGFAELYgsngPQLFTIEQWGTRDKLPRAHTCFNRLDLPPYESFEELREKLHVAIENAQGFD 968
           ********************************************************************8 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

LSLLCRWLNS YAIAVSFITI AQVLSVVFCF TCVFTSPCHF MSFQSETRIL KVKVIEGIGL 60
AKKDILGASD PYTKLSLYDP ATGESNSFHT KTIKKTLDPK WNEEFFFQVD PRKHRLLFEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTACAC TTTCCGCCCA AGTCCGAGGA CTTGACACGG ACCAGGTACC GACACGAAAG 60
CCACTTGGAC GCGCTCGGTG TTTAGCGTTG GTGGGTTCCA TGTTGTTAGC AACAGGCTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001201	Ailuropoda melanoleuca	64.95	0.00e+00	1079.00
IUUC-Apl-003886	Anas platyrhynchos	64.54	0.00e+00	1168.00
IUUC-Acl-008273	Aspergillus clavatus	48.16	9.00e-156	543.00
IUUC-Afl-008713	Aspergillus flavus	45.12	1.00e-150	527.00
IUUC-Afu-009103	Aspergillus fumigatus	48.33	2.00e-156	546.00
IUUC-Ani-009259	Aspergillus nidulans	48.91	5.00e-155	541.00
IUUC-Ang-009738	Aspergillus niger	47.91	4.00e-151	528.00
IUUC-Ate-010529	Aspergillus terreus	47.74	1.00e-154	540.00
IUUC-Ame-011138	Astyanax mexicanus	90.25	0.00e+00	881.00
IUUC-Bgr-012148	Blumeria graminis	47.20	1.00e-147	516.00
IUUC-Bta-012453	Bos taurus	62.03	0.00e+00	1025.00
IUUC-Bci-013785	Botrytis cinerea	47.53	2.00e-150	526.00
IUUC-Cel-018564	Caenorhabditis elegans	51.95	3.00e-176	611.00
IUUC-Cpo-021648	Cavia porcellus	63.03	0.00e+00	1183.00
IUUC-Csa-023334	Chlorocebus sabaeus	65.16	0.00e+00	1179.00
IUUC-Cin-025157	Ciona intestinalis	51.27	0.00e+00	862.00
IUUC-Csv-026098	Ciona savignyi	58.69	0.00e+00	632.00
IUUC-Cgl-026642	Colletotrichum gloeosporioides	46.60	3.00e-150	525.00
IUUC-Dse-031241	Dothistroma septosporum	46.40	2.00e-151	529.00
IUUC-Dme-032166	Drosophila melanogaster	66.67	0.00e+00	723.00
IUUC-Ete-032409	Echinops telfairi	59.90	0.00e+00	839.00
IUUC-Fca-036384	Felis catus	65.03	0.00e+00	1066.00
IUUC-Fal-037547	Ficedula albicollis	65.11	0.00e+00	1172.00
IUUC-Fox-037774	Fusarium oxysporum	47.60	3.00e-153	535.00
IUUC-Fso-038393	Fusarium solani	47.41	3.00e-149	522.00
IUUC-Ggr-040107	Gaeumannomyces graminis	47.22	5.00e-149	521.00
IUUC-Gga-040524	Gallus gallus	65.35	0.00e+00	1164.00
IUUC-Gac-042607	Gasterosteus aculeatus	72.01	0.00e+00	1320.00
IUUC-Itr-048383	Ictidomys tridecemlineatus	58.66	0.00e+00	851.00
IUUC-Kpa-049273	Komagataella pastoris	47.85	1.00e-155	543.00
IUUC-Lch-050445	Latimeria chalumnae	66.01	0.00e+00	1094.00
IUUC-Loc-052645	Lepisosteus oculatus	70.87	0.00e+00	1294.00
IUUC-Meu-056897	Macropus eugenii	87.80	1.00e-156	547.00
IUUC-Mor-057097	Magnaporthe oryzae	44.14	2.00e-151	529.00
IUUC-Mpo-057442	Magnaporthe poae	51.53	6.00e-142	498.00
IUUC-Mla-058996	Melampsora laricipopulina	53.83	8.00e-146	510.00
IUUC-Mga-059362	Meleagris gallopavo	62.82	0.00e+00	1155.00
IUUC-Mvi-060395	Microbotryum violaceum	53.93	4.00e-148	518.00
IUUC-Mmr-061061	Microcebus murinus	65.54	0.00e+00	1075.00
IUUC-Mpu-066567	Mustela putorius furo	65.55	0.00e+00	1201.00
IUUC-Mlu-068148	Myotis lucifugus	65.15	0.00e+00	1059.00
IUUC-Nfi-068427	Neosartorya fischeri	48.33	2.00e-156	546.00
IUUC-Ncr-068918	Neurospora crassa	47.80	2.00e-152	532.00
IUUC-Nle-069225	Nomascus leucogenys	65.51	0.00e+00	1086.00
IUUC-Ont-071664	Oreochromis niloticus	71.92	0.00e+00	1295.00
IUUC-Oan-073019	Ornithorhynchus anatinus	66.96	0.00e+00	1142.00
IUUC-Oar-089797	Ovis aries	64.58	0.00e+00	1109.00
IUUC-Pma-094364	Petromyzon marinus	78.13	0.00e+00	805.00
IUUC-Pno-095118	Phaeosphaeria nodorum	48.47	6.00e-154	538.00
IUUC-Ppa-095250	Physcomitrella patens	45.97	1.00e-83	303.00
IUUC-Pfo-097145	Poecilia formosa	70.94	0.00e+00	1274.00
IUUC-Pab-098394	Pongo abelii	65.70	0.00e+00	1179.00
IUUC-Pca-100568	Procavia capensis	59.47	0.00e+00	899.00
IUUC-Pgr-103620	Puccinia graminis	53.21	4.00e-144	504.00
IUUC-Ptt-103806	Puccinia triticina	52.77	1.00e-118	420.00
IUUC-Pte-104016	Pyrenophora teres	49.32	1.00e-154	540.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	49.32	1.00e-154	540.00
IUUC-Sce-106289	Saccharomyces cerevisiae	48.05	1.00e-156	546.00
IUUC-Sha-107370	Sarcophilus harrisii	61.24	0.00e+00	1031.00
IUUC-Spo-108171	Schizosaccharomyces pombe	48.46	1.00e-155	543.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	47.78	9.00e-152	530.00
IUUC-Tgu-117474	Taeniopygia guttata	65.13	0.00e+00	1182.00
IUUC-Tru-117675	Takifugu rubripes	81.46	0.00e+00	1480.00
IUUC-Tvi-122595	Trichoderma virens	46.63	2.00e-150	526.00
IUUC-Tme-126897	Tuber melanosporum	46.76	1.00e-141	496.00
IUUC-Tbe-127408	Tupaia belangeri	60.69	0.00e+00	808.00
IUUC-Uma-129332	Ustilago maydis	52.26	4.00e-138	485.00
IUUC-Vpa-130503	Vicugna pacos	62.04	0.00e+00	936.00
IUUC-Xtr-132431	Xenopus tropicalis	61.97	0.00e+00	1152.00
IUUC-Xma-133630	Xiphophorus maculatus	67.61	0.00e+00	1110.00
IUUC-Yli-134668	Yarrowia lipolytica	45.06	2.00e-150	526.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence