iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sja-107889

Ensembl Protein ID

EEB09244

UniProt Accession

B6K6U0; B6K6U0_SCHJY

Genbank Protein ID

EEB09244.1

Protein Name

Ubiquitin-protein ligase E3

Genbank Nucleotide ID

KE651167

Gene Name

SJAG_04429

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SJAG_04429	EEB09244	EEB09244

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.50e-100	334.1	669	1000

Active Site

Position(s)	Description	Evidence
969	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfykl 99
           k  ++++fv+     Eeg+d gG+t+efl+ +++ ++++++glf  se+  + l+p+ +++ ++pe+l ++eflG+l+gk++++g  +d+ ++++f+ +
   Q: 669  KGPIKITFVDehgvvEEGIDGGGLTKEFLTSICRTVFDTNYGLF--SETFANLLYPSTKAYAQDPERLHYYEFLGMLIGKCIYEGIQIDAAFAPFFIAK 765
           56688999999999999***************************..777788999******************************************** PP
   S: 100  llgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfn 198
            lg++ +++dl+++d +ly+ l ++k++ + d+e+  l l+f+v +e++g  +e +L+p+G+ni+Vt++N+ +Y++lv +y l+ +  +q +af +Gf+
   Q: 766  WLGHPSHIDDLAALDLKLYEGLAFLKHY-KGDVEND-LSLSFTVVHEEFGVKEEIDLIPNGKNISVTEANRLQYIHLVSNYYLNARLSKQSKAFTQGFT 862
           ****************************.6788885.************************************************************** PP
   S: 199  eviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd. 295
           ++i++++l++F+e+el+ll+ G   +idv+dl+k+t y g++ e+sp+i +Fw+vl+efs+++++a+L+FvT+  r P+ Gf+el+  lf+ir +++d 
   Q: 863  QLINPHWLAMFHENELQLLVGGApVSIDVDDLRKHTVYAGEFDENSPTILFFWQVLREFSEDDKRALLKFVTSVARPPILGFKELN-PLFCIRSNGNDe 960
           ***********************99*************************************************************.56*****87777 PP
   S: 296  drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           +rlP+++TC+n+LkLP Y sk+il++kL +Ai+ ++gF++
   Q: 961  TRLPTASTCVNLLKLPVYGSKQILRDKLSIAIQANTGFGF 1000
           **************************************97 PP

Organism

Schizosaccharomyces japonicus

Protein Sequence
(Fasta)

MSFDGNFKPR RQINLGGRRP DTDKNRILRR AALERKQRAE DRRLSELSIK LQAHVRRWLF 60
QQRFHRECRE IWFQKYRPEQ LVQVKEPREL HDMGNVEYWG NCIRQFCMFA SLPEDEEGLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGGAAGCAG GATGCGATAC CGCGGAAAGC CCGGACTTAC CTTGTCCACA ATAGTAAGGA 60
CAGAACGTTT CTGTTGAGGA TGATTAGAGC TTACGCGCAA GCGACGAGAC GCGATCACCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	35.25	3.00e-84	305.00
IUUC-Aml-001355	Ailuropoda melanoleuca	42.49	3.00e-94	338.00
IUUC-Atr-002669	Amborella trichopoda	34.74	4.00e-86	310.00
IUUC-Apl-003731	Anas platyrhynchos	44.39	2.00e-98	352.00
IUUC-Aca-005248	Anolis carolinensis	44.39	2.00e-98	352.00
IUUC-Aly-005768	Arabidopsis lyrata	36.75	5.00e-98	350.00
IUUC-Ath-006576	Arabidopsis thaliana	36.04	3.00e-97	347.00
IUUC-Ago-007748	Ashbya gossypii	39.71	2.00e-77	281.00
IUUC-Acl-008158	Aspergillus clavatus	32.81	8.00e-85	306.00
IUUC-Afl-008398	Aspergillus flavus	40.64	6.00e-85	307.00
IUUC-Afu-008937	Aspergillus fumigatus	33.29	3.00e-85	308.00
IUUC-Ani-009252	Aspergillus nidulans	41.61	4.00e-95	340.00
IUUC-Ang-009773	Aspergillus niger	40.21	3.00e-84	305.00
IUUC-Aor-009940	Aspergillus oryzae	40.64	6.00e-85	307.00
IUUC-Ate-010395	Aspergillus terreus	39.15	2.00e-83	302.00
IUUC-Ame-010769	Astyanax mexicanus	37.86	3.00e-76	278.00
IUUC-Bgr-012269	Blumeria graminis	40.26	1.00e-83	301.00
IUUC-Bta-012841	Bos taurus	42.96	1.00e-95	342.00
IUUC-Bci-013743	Botrytis cinerea	36.72	2.00e-94	338.00
IUUC-Bdi-014123	Brachypodium distachyon	38.73	1.00e-94	338.00
IUUC-Bol-015390	Brassica oleracea	36.46	1.00e-91	329.00
IUUC-Bra-016853	Brassica rapa	36.46	3.00e-97	347.00
IUUC-Cel-018447	Caenorhabditis elegans	38.33	2.00e-73	268.00
IUUC-Cja-019743	Callithrix jacchus	42.89	6.00e-95	340.00
IUUC-Cfa-021031	Canis familiaris	43.19	3.00e-96	344.00
IUUC-Cpo-022401	Cavia porcellus	42.96	2.00e-95	342.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	35.38	1.00e-67	249.00
IUUC-Csa-024107	Chlorocebus sabaeus	42.25	6.00e-94	337.00
IUUC-Cho-024750	Choloepus hoffmanni	45.59	1.00e-84	306.00
IUUC-Cin-025750	Ciona intestinalis	34.46	3.00e-80	291.00
IUUC-Csv-026016	Ciona savignyi	38.27	9.00e-78	283.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	31.60	5.00e-96	344.00
IUUC-Cne-026841	Cryptococcus neoformans	38.20	8.00e-103	366.00
IUUC-Cme-027265	Cyanidioschyzon merolae	41.28	4.00e-90	324.00
IUUC-Dre-028196	Danio rerio	44.13	1.00e-98	352.00
IUUC-Dno-029024	Dasypus novemcinctus	42.96	3.00e-96	344.00
IUUC-Dor-030938	Dipodomys ordii	39.23	1.00e-79	289.00
IUUC-Dse-031416	Dothistroma septosporum	36.64	1.00e-92	332.00
IUUC-Dme-031946	Drosophila melanogaster	41.75	1.00e-87	316.00
IUUC-Ete-033041	Echinops telfairi	36.79	3.00e-52	198.00
IUUC-Eca-033828	Equus caballus	43.19	2.00e-96	345.00
IUUC-Eeu-035201	Erinaceus europaeus	37.79	7.00e-56	210.00
IUUC-Fca-035907	Felis catus	40.25	2.00e-96	345.00
IUUC-Fal-037389	Ficedula albicollis	44.39	4.00e-98	350.00
IUUC-Fox-037788	Fusarium oxysporum	35.37	2.00e-94	338.00
IUUC-Fso-038088	Fusarium solani	34.20	4.00e-93	334.00
IUUC-Gmo-039412	Gadus morhua	38.98	2.00e-82	298.00
IUUC-Ggr-039941	Gaeumannomyces graminis	36.10	4.00e-99	354.00
IUUC-Gga-040310	Gallus gallus	43.53	3.00e-98	351.00
IUUC-Gac-042088	Gasterosteus aculeatus	39.44	3.00e-83	301.00
IUUC-Gma-042836	Glycine max	36.39	7.00e-95	340.00
IUUC-Ggo-045031	Gorilla gorilla	42.49	2.00e-94	338.00
IUUC-Hsa-045880	Homo sapiens	42.49	2.00e-94	338.00
IUUC-Hvu-047770	Hordeum vulgare	37.14	2.00e-95	341.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	39.00	1.00e-78	285.00
IUUC-Kpa-049307	Komagataella pastoris	32.53	3.00e-70	258.00
IUUC-Lch-050664	Latimeria chalumnae	39.12	4.00e-82	297.00
IUUC-Lpe-051428	Leersia perrieri	38.46	2.00e-84	305.00
IUUC-Loc-052218	Lepisosteus oculatus	43.22	7.00e-98	350.00
IUUC-Lma-053096	Leptosphaeria maculans	33.29	2.00e-93	335.00
IUUC-Laf-053902	Loxodonta africana	38.05	2.00e-81	295.00
IUUC-Mcc-055127	Macaca mulatta	42.49	2.00e-94	338.00
IUUC-Meu-056527	Macropus eugenii	39.74	1.00e-61	229.00
IUUC-Mor-057021	Magnaporthe oryzae	41.13	4.00e-85	308.00
IUUC-Mpo-057570	Magnaporthe poae	41.61	3.00e-95	341.00
IUUC-Mtr-058154	Medicago truncatula	35.92	1.00e-94	339.00
IUUC-Mla-059124	Melampsora laricipopulina	47.76	5.00e-108	382.00
IUUC-Mga-059581	Meleagris gallopavo	44.39	3.00e-98	351.00
IUUC-Mvi-060445	Microbotryum violaceum	40.54	4.00e-123	434.00
IUUC-Mmr-061360	Microcebus murinus	42.72	6.00e-95	340.00
IUUC-Mdo-062194	Monodelphis domestica	43.06	1.00e-96	346.00
IUUC-Mmu-064189	Mus musculus	43.39	1.00e-93	336.00
IUUC-Mac-065275	Musa acuminata	38.65	2.00e-99	354.00
IUUC-Mpu-066439	Mustela putorius furo	44.64	4.00e-97	347.00
IUUC-Mlu-068228	Myotis lucifugus	43.19	2.00e-96	345.00
IUUC-Nfi-068280	Neosartorya fischeri	40.21	3.00e-84	305.00
IUUC-Ncr-068869	Neurospora crassa	36.57	4.00e-92	330.00
IUUC-Nle-069687	Nomascus leucogenys	42.02	1.00e-93	335.00
IUUC-Opr-070554	Ochotona princeps	38.28	8.00e-81	293.00
IUUC-Ont-071836	Oreochromis niloticus	43.90	1.00e-98	352.00
IUUC-Oan-072800	Ornithorhynchus anatinus	44.39	1.00e-97	349.00
IUUC-Ocu-074587	Oryctolagus cuniculus	43.89	3.00e-95	341.00
IUUC-Oba-075006	Oryza barthii	37.77	2.00e-93	335.00
IUUC-Obr-076133	Oryza brachyantha	37.96	6.00e-94	337.00
IUUC-Ogl-077003	Oryza glaberrima	37.77	2.00e-93	335.00
IUUC-Ogu-078947	Oryza glumaepatula	37.66	1.00e-93	335.00
IUUC-Oin-080058	Oryza indica	41.13	3.00e-87	315.00
IUUC-Olo-080475	Oryza longistaminata	37.66	1.00e-93	336.00
IUUC-Ome-081342	Oryza meridionalis	36.04	4.00e-83	301.00
IUUC-Oni-082385	Oryza nivara	37.66	1.00e-93	335.00
IUUC-Opu-083176	Oryza punctata	43.21	1.00e-92	332.00
IUUC-Oru-084554	Oryza rufipogon	35.86	3.00e-83	301.00
IUUC-Osa-085355	Oryza sativa	37.66	8.00e-94	336.00
IUUC-Ola-087209	Oryzias latipes	44.64	8.00e-98	349.00
IUUC-Olu-087902	Ostreococcus lucimarinus	38.00	2.00e-76	277.00
IUUC-Oga-088776	Otolemur garnettii	42.49	3.00e-94	338.00
IUUC-Oar-089441	Ovis aries	42.96	1.00e-95	342.00
IUUC-Ptr-091273	Pan troglodytes	42.49	2.00e-94	338.00
IUUC-Pan-091981	Papio anubis	42.49	2.00e-94	338.00
IUUC-Psi-093251	Pelodiscus sinensis	38.01	4.00e-69	254.00
IUUC-Pma-094738	Petromyzon marinus	44.64	2.00e-94	338.00
IUUC-Pno-095132	Phaeosphaeria nodorum	31.50	3.00e-71	261.00
IUUC-Ppa-095682	Physcomitrella patens	36.53	2.00e-96	344.00
IUUC-Pfo-097511	Poecilia formosa	43.90	9.00e-99	353.00
IUUC-Pab-098570	Pongo abelii	38.52	2.00e-81	295.00
IUUC-Pop-098928	Populus trichocarpa	32.72	2.00e-90	325.00
IUUC-Pca-100987	Procavia capensis	44.16	3.00e-91	327.00
IUUC-Ppe-102040	Prunus persica	39.93	7.00e-94	336.00
IUUC-Pva-103034	Pteropus vampyrus	39.91	3.00e-83	301.00
IUUC-Pgr-103513	Puccinia graminis	37.32	1.00e-119	422.00
IUUC-Ptt-103967	Puccinia triticina	35.64	3.00e-103	368.00
IUUC-Pte-104105	Pyrenophora teres	33.15	9.00e-94	336.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	32.17	4.00e-94	337.00
IUUC-Rno-106028	Rattus norvegicus	36.49	6.00e-67	247.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.79	2.00e-76	278.00
IUUC-Sha-107108	Sarcophilus harrisii	40.85	6.00e-87	313.00
IUUC-Spo-108097	Schizosaccharomyces pombe	45.91	0.00e+00	823.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	41.54	2.00e-92	332.00
IUUC-Smo-109537	Selaginella moellendorffii	42.00	1.00e-90	326.00
IUUC-Sit-110457	Setaria italica	36.65	9.00e-86	309.00
IUUC-Sly-111362	Solanum lycopersicum	35.87	2.00e-94	338.00
IUUC-Sbi-113882	Sorghum bicolor	33.48	3.00e-85	308.00
IUUC-Sre-115038	Sporisorium reilianum	48.51	3.00e-106	378.00
IUUC-Ssc-116103	Sus scrofa	38.52	7.00e-81	293.00
IUUC-Tgu-116729	Taeniopygia guttata	43.29	9.00e-98	349.00
IUUC-Tru-118068	Takifugu rubripes	45.39	3.00e-99	354.00
IUUC-Tsy-118942	Tarsius syrichta	47.27	1.00e-66	246.00
IUUC-Tni-120732	Tetraodon nigroviridis	43.06	1.00e-94	339.00
IUUC-Tca-121737	Theobroma cacao	38.47	4.00e-102	363.00
IUUC-Tre-121892	Trichoderma reesei	41.80	5.00e-94	337.00
IUUC-Tvi-122354	Trichoderma virens	30.71	5.00e-92	330.00
IUUC-Tae-125229	Triticum aestivum	36.40	4.00e-95	341.00
IUUC-Tur-126086	Triticum urartu	38.10	3.00e-84	305.00
IUUC-Tme-127102	Tuber melanosporum	34.64	7.00e-104	370.00
IUUC-Tbe-127351	Tupaia belangeri	40.81	1.00e-77	282.00
IUUC-Ttr-129061	Tursiops truncatus	43.64	3.00e-90	324.00
IUUC-Uma-129343	Ustilago maydis	48.76	8.00e-111	393.00
IUUC-Vda-129748	Verticillium dahliae	30.16	7.00e-88	317.00
IUUC-Vvi-131234	Vitis vinifera	35.88	4.00e-91	327.00
IUUC-Xtr-132094	Xenopus tropicalis	43.64	2.00e-94	338.00
IUUC-Xma-133923	Xiphophorus maculatus	43.90	7.00e-99	353.00
IUUC-Yli-134496	Yarrowia lipolytica	37.73	3.00e-86	311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence