iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090138

Ensembl Protein ID

ENSOARP00000008837.1

UniProt Accession

W5PEH3; W5PEH3_SHEEP

Genbank Protein ID

ENSOARP00000008837

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01110767

Gene Name

NSMCE2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000008238.1	ENSOART00000008965.1	ENSOARP00000008837.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.70e-09	37.8	195	271

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlp.sGitydrssIekwlasggk.....tcPvtrqpl...teedlvPnltlrrliqawcee 71
             f+CpI+   M+ Pv  + +G+ty+ ++I + ++s++k      cP+ + +    + +dl+   +lrr i+++ ++
   Q: 195  TNFICPITQLEMKKPVKNKvCGHTYEEEAIVRMIESKHKrkkkaCCPKIGCSHtdmRMSDLIQDEALRRAIESHNKK 271
           57********************************99999999998887655442227799***********998766 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MPGRSTSSSG SGSTGFISFS GVESALSSLK NFQSCISSGM DTASSVALDL VETQTEVSSE 60
YSMDKAMVEF AMMDRELNHY LKAVQSTINH VKEERSEKIP DLKLLVEKKF LALQNKNSDA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAATAATTT CAAGATGCCG GGGCGTTCCA CTTCAAGTTC AGGTTCAGGT TCAACTGGTT 60
TTATATCCTT CAGTGGTGTA GAATCTGCAC TGTCCTCCTT GAAAAACTTC CAATCCTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR026846--Nse2(Mms21)
IPR003613--Ubox_domain
IPR004181--Znf_MIZ
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51044--ZF_SP_RING

Pfam

PF11789--zf-Nse

SMART

SM00504--Ubox

Gene Ontology

GO:0000781--C:chromosome, telomeric region
GO:0016605--C:PML body
GO:0030915--C:Smc5-Smc6 complex
GO:0019789--F:SUMO transferase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0000724--P:double-strand break repair via homologous recombination
GO:0034184--P:positive regulation of maintenance of mitotic sister chromatid cohesion
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0000722--P:telomere maintenance via recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001627	Ailuropoda melanoleuca	80.56	4.00e-104	370.00
IUUC-Atr-002438	Amborella trichopoda	34.85	3.00e-06	45.40
IUUC-Apl-004091	Anas platyrhynchos	65.59	5.00e-31	125.00
IUUC-Aca-004433	Anolis carolinensis	45.70	1.00e-62	232.00
IUUC-Ago-007852	Ashbya gossypii	28.26	1.00e-07	49.70
IUUC-Acl-008011	Aspergillus clavatus	32.56	5.00e-03	35.80
IUUC-Afl-008461	Aspergillus flavus	46.67	7.00e-03	35.40
IUUC-Afu-008893	Aspergillus fumigatus	32.56	1.00e-03	38.10
IUUC-Ani-009414	Aspergillus nidulans	31.82	5.00e-04	39.30
IUUC-Ang-009587	Aspergillus niger	46.67	3.00e-03	37.00
IUUC-Ate-010326	Aspergillus terreus	34.88	1.00e-02	36.20
IUUC-Ame-010902	Astyanax mexicanus	36.58	3.00e-40	158.00
IUUC-Bgr-012088	Blumeria graminis	22.73	9.00e-07	47.80
IUUC-Bta-013397	Bos taurus	83.90	7.00e-74	269.00
IUUC-Bci-013738	Botrytis cinerea	26.32	6.00e-06	45.40
IUUC-Cja-019246	Callithrix jacchus	83.14	1.00e-108	385.00
IUUC-Cpo-021670	Cavia porcellus	74.80	1.00e-94	338.00
IUUC-Csa-023982	Chlorocebus sabaeus	79.20	5.00e-100	356.00
IUUC-Cin-025127	Ciona intestinalis	37.63	4.00e-13	68.20
IUUC-Cgl-026430	Colletotrichum gloeosporioides	24.02	2.00e-08	53.10
IUUC-Cne-026806	Cryptococcus neoformans	36.59	4.00e-08	52.00
IUUC-Cme-027175	Cyanidioschyzon merolae	29.31	3.00e-05	42.40
IUUC-Dre-028325	Danio rerio	32.51	9.00e-30	123.00
IUUC-Dno-029735	Dasypus novemcinctus	81.96	6.00e-119	419.00
IUUC-Dor-030454	Dipodomys ordii	66.93	2.00e-74	271.00
IUUC-Dse-031273	Dothistroma septosporum	33.33	5.00e-04	39.30
IUUC-Dme-031971	Drosophila melanogaster	27.39	3.00e-08	51.60
IUUC-Ete-032838	Echinops telfairi	56.83	6.00e-50	189.00
IUUC-Eca-034371	Equus caballus	79.61	8.00e-114	402.00
IUUC-Eeu-035258	Erinaceus europaeus	78.04	2.00e-81	294.00
IUUC-Fca-035576	Felis catus	80.56	5.00e-104	370.00
IUUC-Fal-037038	Ficedula albicollis	50.59	3.00e-70	257.00
IUUC-Fox-037843	Fusarium oxysporum	32.86	3.00e-06	46.20
IUUC-Fso-038272	Fusarium solani	34.57	7.00e-06	45.10
IUUC-Ggr-040059	Gaeumannomyces graminis	28.57	1.00e-06	47.40
IUUC-Gga-040737	Gallus gallus	42.66	5.00e-53	200.00
IUUC-Gac-042591	Gasterosteus aculeatus	37.26	3.00e-38	151.00
IUUC-Gma-043177	Glycine max	30.85	6.00e-07	48.10
IUUC-Ggo-045206	Gorilla gorilla	78.43	2.00e-101	361.00
IUUC-Hsa-046704	Homo sapiens	78.82	4.00e-102	363.00
IUUC-Itr-048972	Ictidomys tridecemlineatus	93.33	6.00e-47	179.00
IUUC-Kpa-049181	Komagataella pastoris	31.31	2.00e-10	59.30
IUUC-Loc-052687	Lepisosteus oculatus	38.19	8.00e-38	150.00
IUUC-Lma-053255	Leptosphaeria maculans	31.34	9.00e-06	45.10
IUUC-Laf-054270	Loxodonta africana	76.09	3.00e-106	377.00
IUUC-Mcc-054757	Macaca mulatta	77.03	3.00e-78	283.00
IUUC-Mor-057028	Magnaporthe oryzae	25.60	5.00e-07	48.90
IUUC-Mpo-057462	Magnaporthe poae	28.57	2.00e-07	50.10
IUUC-Mtr-058011	Medicago truncatula	24.30	1.00e-07	49.70
IUUC-Mga-059215	Meleagris gallopavo	67.07	3.00e-32	129.00
IUUC-Mvi-060511	Microbotryum violaceum	32.47	2.00e-07	50.40
IUUC-Mmr-061584	Microcebus murinus	78.91	3.00e-100	357.00
IUUC-Mdo-061863	Monodelphis domestica	49.62	3.00e-71	261.00
IUUC-Mmu-064413	Mus musculus	80.46	2.00e-110	391.00
IUUC-Mpu-066092	Mustela putorius furo	92.06	2.00e-126	444.00
IUUC-Mlu-068198	Myotis lucifugus	81.82	6.00e-118	416.00
IUUC-Nfi-068508	Neosartorya fischeri	27.94	9.00e-04	38.50
IUUC-Ncr-068773	Neurospora crassa	29.89	8.00e-06	44.70
IUUC-Nle-070109	Nomascus leucogenys	79.61	6.00e-104	370.00
IUUC-Opr-070540	Ochotona princeps	76.92	4.00e-36	144.00
IUUC-Ont-071575	Oreochromis niloticus	36.43	5.00e-40	157.00
IUUC-Oan-072777	Ornithorhynchus anatinus	76.19	1.00e-23	100.00
IUUC-Ocu-074730	Oryctolagus cuniculus	84.13	7.00e-109	386.00
IUUC-Oga-087925	Otolemur garnettii	83.53	5.00e-101	360.00
IUUC-Ptr-091582	Pan troglodytes	78.82	4.00e-102	363.00
IUUC-Pan-092890	Papio anubis	79.20	5.00e-100	356.00
IUUC-Psi-093714	Pelodiscus sinensis	52.33	4.00e-71	261.00
IUUC-Pma-094198	Petromyzon marinus	28.24	2.00e-16	78.20
IUUC-Pno-094931	Phaeosphaeria nodorum	32.47	2.00e-05	43.90
IUUC-Pab-098005	Pongo abelii	78.43	7.00e-102	363.00
IUUC-Pop-099559	Populus trichocarpa	31.03	2.00e-05	42.70
IUUC-Pca-100368	Procavia capensis	56.86	3.00e-60	224.00
IUUC-Ppe-101873	Prunus persica	34.38	5.00e-07	47.80
IUUC-Pva-102951	Pteropus vampyrus	82.86	1.00e-112	398.00
IUUC-Pte-104390	Pyrenophora teres	38.57	5.00e-06	45.40
IUUC-Pyt-104633	Pyrenophora triticirepentis	38.57	6.00e-06	45.40
IUUC-Rno-105346	Rattus norvegicus	78.62	1.00e-110	392.00
IUUC-Sha-107586	Sarcophilus harrisii	57.32	8.00e-38	149.00
IUUC-Sja-107983	Schizosaccharomyces japonicus	35.05	3.00e-11	62.40
IUUC-Spo-108327	Schizosaccharomyces pombe	28.02	1.00e-07	49.70
IUUC-Ssl-108555	Sclerotinia sclerotiorum	26.97	6.00e-06	45.40
IUUC-Sly-111667	Solanum lycopersicum	30.30	5.00e-05	41.20
IUUC-Stu-112211	Solanum tuberosum	33.33	8.00e-06	43.90
IUUC-Sar-113609	Sorex araneus	76.15	5.00e-100	356.00
IUUC-Sre-115187	Sporisorium reilianum	25.60	4.00e-06	45.40
IUUC-Tgu-116472	Taeniopygia guttata	48.24	1.00e-64	239.00
IUUC-Tru-117771	Takifugu rubripes	35.00	2.00e-35	142.00
IUUC-Tni-119821	Tetraodon nigroviridis	33.72	4.00e-38	151.00
IUUC-Tca-121272	Theobroma cacao	34.85	8.00e-05	40.80
IUUC-Tre-122049	Trichoderma reesei	28.65	5.00e-10	58.50
IUUC-Tvi-122642	Trichoderma virens	30.49	1.00e-07	50.80
IUUC-Tme-126988	Tuber melanosporum	30.11	5.00e-07	48.50
IUUC-Tbe-127676	Tupaia belangeri	80.72	5.00e-90	323.00
IUUC-Ttr-128602	Tursiops truncatus	83.00	9.00e-108	382.00
IUUC-Uma-129520	Ustilago maydis	28.57	1.00e-04	40.80
IUUC-Vpa-130510	Vicugna pacos	83.79	6.00e-109	386.00
IUUC-Vvi-131486	Vitis vinifera	39.39	2.00e-07	49.30
IUUC-Yli-134676	Yarrowia lipolytica	30.23	2.00e-06	46.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence