iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000008604.7	ENSRNOT00000011654.6	ENSRNOP00000011654.3
ENSRNOG00000008604.7	ENSRNOT00000090211.1	ENSRNOP00000074814.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	miRNAMap	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
Phospho.ELM	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/UBX	4.00e-17	62.9	292	367

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve.yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsll 78
           +++++++qiRl+dG rlv+kF++s+++++i+ f+   +  +  + F L+++fP+++l++e++  tl+ea+L++  +++
   Q: 292  AEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVdARPAMAATSFVLMTTFPNKELADENQ--TLKEANLLNAVIVQ 367
           6889*******************************9999***********************..*********99986 PP

Organism

Rattus norvegicus

Functional Description
(View)

Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER).

Protein Sequence
(Fasta)

MAEERQDALR EFVAVTGAEE DRARFFLESA GWDLQIALAS FYEDGGDEDI VTISQATPSS 60
VSRGTAPSDN RVTSFRDLIH DQDEEEEEEE GQRFYAGGSE RSGQQIVGPP RKKSPNELVD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCAGGCGCC CTGCCGCTGG ACACTGTAGA ACGGCGGGCG GAACGCAGAC CTGGGTTCGG 60
GCTGTTGCAG TGTCCGCCGG AGCGGTTTGG GGAGTGCACG GGGTGAAGAT GGCGGAGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0158--Chromosome
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0333--Golgi apparatus
KW-0446--Lipid-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR012989--SEP_domain
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS51399--SEP
PS50033--UBX

Pfam

PF08059--SEP
PF00789--UBX

SMART

SM00553--SEP
SM00166--UBX

Gene Ontology

GO:0005694--C:chromosome
GO:0005829--C:cytosol
GO:0005795--C:Golgi stack
GO:0045111--C:intermediate filament cytoskeleton
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:1990730--C:VCP-NSFL1C complex
GO:0051117--F:ATPase binding
GO:0008289--F:lipid binding
GO:0043130--F:ubiquitin binding
GO:0007030--P:Golgi organization
GO:0061025--P:membrane fusion
GO:0031468--P:nuclear envelope reassembly
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

KEGG

rno:83809

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000550	Aegilops tauschii	36.36	6.00e-35	140.00
IUUC-Aml-001919	Ailuropoda melanoleuca	95.99	0.00e+00	706.00
IUUC-Atr-002543	Amborella trichopoda	30.73	3.00e-39	155.00
IUUC-Apl-003388	Anas platyrhynchos	86.83	0.00e+00	629.00
IUUC-Aca-005210	Anolis carolinensis	86.34	0.00e+00	637.00
IUUC-Aly-006329	Arabidopsis lyrata	34.29	3.00e-35	142.00
IUUC-Ath-007064	Arabidopsis thaliana	36.33	2.00e-34	139.00
IUUC-Ago-007933	Ashbya gossypii	27.84	2.00e-18	87.00
IUUC-Ani-009398	Aspergillus nidulans	30.65	7.00e-38	150.00
IUUC-Ang-009594	Aspergillus niger	32.62	4.00e-29	122.00
IUUC-Ate-010455	Aspergillus terreus	34.49	3.00e-34	139.00
IUUC-Ame-011089	Astyanax mexicanus	72.24	2.00e-149	521.00
IUUC-Bta-012898	Bos taurus	97.57	0.00e+00	724.00
IUUC-Bdi-014746	Brachypodium distachyon	34.64	1.00e-35	143.00
IUUC-Bol-015874	Brassica oleracea	30.65	1.00e-36	146.00
IUUC-Bra-017734	Brassica rapa	34.74	6.00e-34	137.00
IUUC-Cel-018169	Caenorhabditis elegans	40.18	2.00e-38	152.00
IUUC-Cja-018993	Callithrix jacchus	96.24	0.00e+00	714.00
IUUC-Cfa-020958	Canis familiaris	97.30	0.00e+00	723.00
IUUC-Cpo-021417	Cavia porcellus	96.49	0.00e+00	715.00
IUUC-Csa-023244	Chlorocebus sabaeus	96.49	0.00e+00	718.00
IUUC-Cho-024335	Choloepus hoffmanni	74.90	1.00e-98	352.00
IUUC-Cin-025686	Ciona intestinalis	47.53	2.00e-91	329.00
IUUC-Csv-025945	Ciona savignyi	44.02	2.00e-86	312.00
IUUC-Cne-026798	Cryptococcus neoformans	37.93	1.00e-35	144.00
IUUC-Cme-027347	Cyanidioschyzon merolae	32.03	7.00e-28	117.00
IUUC-Dre-028748	Danio rerio	71.00	3.00e-146	511.00
IUUC-Dno-029977	Dasypus novemcinctus	96.77	0.00e+00	716.00
IUUC-Dor-030203	Dipodomys ordii	95.85	0.00e+00	640.00
IUUC-Dse-031256	Dothistroma septosporum	31.19	2.00e-30	126.00
IUUC-Dme-031878	Drosophila melanogaster	44.41	5.00e-60	224.00
IUUC-Ete-032997	Echinops telfairi	95.12	0.00e+00	700.00
IUUC-Eca-034132	Equus caballus	97.92	0.00e+00	658.00
IUUC-Eeu-035097	Erinaceus europaeus	71.56	1.00e-83	303.00
IUUC-Fca-036037	Felis catus	96.76	0.00e+00	653.00
IUUC-Fal-037100	Ficedula albicollis	85.88	2.00e-173	601.00
IUUC-Fso-038190	Fusarium solani	26.28	1.00e-28	120.00
IUUC-Gmo-039429	Gadus morhua	66.40	2.00e-131	461.00
IUUC-Gga-040864	Gallus gallus	87.74	0.00e+00	654.00
IUUC-Gac-041589	Gasterosteus aculeatus	70.08	7.00e-146	509.00
IUUC-Ggo-044601	Gorilla gorilla	95.97	0.00e+00	713.00
IUUC-Hsa-045773	Homo sapiens	96.49	0.00e+00	718.00
IUUC-Itr-047949	Ictidomys tridecemlineatus	96.77	0.00e+00	718.00
IUUC-Kpa-049322	Komagataella pastoris	33.45	1.00e-29	124.00
IUUC-Lch-050608	Latimeria chalumnae	74.73	2.00e-161	561.00
IUUC-Lpe-050944	Leersia perrieri	34.08	1.00e-30	128.00
IUUC-Loc-052555	Lepisosteus oculatus	74.39	1.00e-158	552.00
IUUC-Laf-054237	Loxodonta africana	96.51	0.00e+00	717.00
IUUC-Mcc-055472	Macaca mulatta	95.70	0.00e+00	712.00
IUUC-Meu-056093	Macropus eugenii	71.75	3.00e-124	437.00
IUUC-Mor-057220	Magnaporthe oryzae	25.38	7.00e-29	121.00
IUUC-Mtr-058376	Medicago truncatula	35.56	8.00e-34	137.00
IUUC-Mla-059077	Melampsora laricipopulina	33.75	6.00e-35	141.00
IUUC-Mga-059836	Meleagris gallopavo	86.76	9.00e-173	599.00
IUUC-Mvi-060292	Microbotryum violaceum	37.70	2.00e-31	130.00
IUUC-Mmr-060897	Microcebus murinus	96.77	0.00e+00	716.00
IUUC-Mdo-062066	Monodelphis domestica	89.89	0.00e+00	675.00
IUUC-Mmu-063686	Mus musculus	99.19	0.00e+00	733.00
IUUC-Mac-065403	Musa acuminata	33.92	6.00e-32	131.00
IUUC-Mpu-065688	Mustela putorius furo	97.57	0.00e+00	725.00
IUUC-Mlu-067566	Myotis lucifugus	93.24	0.00e+00	673.00
IUUC-Nle-069169	Nomascus leucogenys	96.14	0.00e+00	652.00
IUUC-Opr-070979	Ochotona princeps	93.79	2.00e-179	621.00
IUUC-Ont-071803	Oreochromis niloticus	68.11	2.00e-142	498.00
IUUC-Ocu-074276	Oryctolagus cuniculus	96.77	0.00e+00	716.00
IUUC-Ola-086761	Oryzias latipes	68.38	2.00e-136	478.00
IUUC-Olu-087598	Ostreococcus lucimarinus	32.75	2.00e-31	129.00
IUUC-Oga-088533	Otolemur garnettii	97.03	0.00e+00	719.00
IUUC-Oar-089450	Ovis aries	97.84	0.00e+00	724.00
IUUC-Ptr-090926	Pan troglodytes	96.49	0.00e+00	718.00
IUUC-Pan-092100	Papio anubis	96.22	0.00e+00	716.00
IUUC-Psi-093446	Pelodiscus sinensis	85.76	5.00e-166	576.00
IUUC-Pma-094475	Petromyzon marinus	66.31	7.00e-104	370.00
IUUC-Ppa-095833	Physcomitrella patens	33.66	6.00e-35	141.00
IUUC-Pfo-096193	Poecilia formosa	70.08	3.00e-147	514.00
IUUC-Pab-097971	Pongo abelii	96.49	0.00e+00	718.00
IUUC-Pop-098970	Populus trichocarpa	34.06	2.00e-42	166.00
IUUC-Pca-100390	Procavia capensis	96.65	1.00e-128	451.00
IUUC-Pva-102504	Pteropus vampyrus	88.17	0.00e+00	641.00
IUUC-Pgr-103447	Puccinia graminis	38.34	9.00e-33	134.00
IUUC-Ptt-103729	Puccinia triticina	33.55	3.00e-36	146.00
IUUC-Pyt-104504	Pyrenophora triticirepentis	32.19	7.00e-35	141.00
IUUC-Sce-106457	Saccharomyces cerevisiae	31.23	2.00e-29	123.00
IUUC-Spo-108358	Schizosaccharomyces pombe	29.01	1.00e-31	130.00
IUUC-Smo-109535	Selaginella moellendorffii	35.49	6.00e-33	134.00
IUUC-Sit-110328	Setaria italica	35.15	9.00e-34	137.00
IUUC-Sly-111135	Solanum lycopersicum	30.62	2.00e-39	156.00
IUUC-Stu-112733	Solanum tuberosum	33.22	1.00e-36	147.00
IUUC-Sar-113445	Sorex araneus	78.62	8.00e-129	452.00
IUUC-Sbi-114761	Sorghum bicolor	35.99	2.00e-33	135.00
IUUC-Ssc-116008	Sus scrofa	97.57	0.00e+00	723.00
IUUC-Tgu-117238	Taeniopygia guttata	86.92	0.00e+00	649.00
IUUC-Tru-118521	Takifugu rubripes	64.34	2.00e-135	475.00
IUUC-Tni-119705	Tetraodon nigroviridis	68.00	1.00e-139	489.00
IUUC-Tre-121941	Trichoderma reesei	33.83	1.00e-29	124.00
IUUC-Tvi-122602	Trichoderma virens	26.90	6.00e-27	115.00
IUUC-Tae-123686	Triticum aestivum	37.10	3.00e-37	149.00
IUUC-Tur-126267	Triticum urartu	36.82	4.00e-32	131.00
IUUC-Tme-127193	Tuber melanosporum	33.00	2.00e-38	152.00
IUUC-Tbe-127716	Tupaia belangeri	94.41	2.00e-162	564.00
IUUC-Ttr-128262	Tursiops truncatus	95.16	0.00e+00	702.00
IUUC-Uma-129600	Ustilago maydis	29.78	2.00e-39	156.00
IUUC-Vda-129743	Verticillium dahliae	29.37	1.00e-27	117.00
IUUC-Vpa-130068	Vicugna pacos	96.75	1.00e-170	591.00
IUUC-Xma-133944	Xiphophorus maculatus	69.81	2.00e-147	514.00
IUUC-Zma-135978	Zea mays	35.31	5.00e-34	138.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence