iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Mmu-064173

Ensembl Protein ID

ENSMUSP00000030427.5

UniProt Accession

Q8CB77; Q3UI38; Q80VB2; Q9R0Q5; ELOA1_MOUSE

Genbank Protein ID

BAA84994.1; BAC29497.1; BAE26815.1; BAE27668.1; CAM15908.1; EDL29954.1; AAH49885.1

Protein Name

Elongin-A; Elongin 110 kDa subunit; RNA polymerase II transcription factor SIII subunit A1; SIII p110; Transcription elongation factor B polypeptide 3

Genbank Nucleotide ID

AB025015; AK036592; AK145994; AK147088; AL672076; CH466552; BC049885

Gene Name

Tceb3; Eloa

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000028668.5	ENSMUST00000030427.5	ENSMUSP00000030427.5

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein-protein Interaction
IID	iRefIndex	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
Phospho.ELM	UniProt	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	33.82	2.00e-05	46.20	IUUC-Sce-106376
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	33.82	2.00e-05	46.20	IUUC-Sce-106376

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Functional Description
(View)

SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).

Protein Sequence
(Fasta)

MAAESALQVV EKLQARLAAN PDPKKLLKYL KKLSILPITV DILVETGVGK TVNSFRKHEQ 60
VGNFARDLVA QWKKLVPVER NSEAEDQDFE KNNSRKRPRD ALQREEELEG NYQESWKPSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATACACACAC CCCCAGCGGA GGCCCGGAAG GGACCATTCG CGCTTCCGTC TCCGCCGGGC 60
CCTCACGGAG GGCGGAGTTG CGGCCCGAGG ACGCGACGCG AGCCCAGTTC CGGCGAGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR001810--F-box_dom
IPR010684--RNA_pol_II_trans_fac_SIII_A
IPR003617--TFIIS/CRSP70_N_sub
IPR017923--TFIIS_N

PROSITE

PS50181--FBOX
PS51319--TFIIS_N

Pfam

PF06881--Elongin_A
PF08711--Med26

SMART

SM00509--TFS2N

Gene Ontology

GO:0070449--C:elongin complex
GO:0005615--C:extracellular space
GO:0016021--C:integral component of membrane
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006368--P:transcription elongation from RNA polymerase II promoter

KEGG

mmu:27224

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001705	Ailuropoda melanoleuca	79.84	0.00e+00	1044.00
IUUC-Apl-003659	Anas platyrhynchos	76.32	4.00e-130	458.00
IUUC-Aca-004513	Anolis carolinensis	54.71	0.00e+00	666.00
IUUC-Ago-007835	Ashbya gossypii	27.27	9.00e-06	44.30
IUUC-Acl-008085	Aspergillus clavatus	26.72	3.00e-07	49.70
IUUC-Afu-008931	Aspergillus fumigatus	27.59	3.00e-07	49.70
IUUC-Ani-009161	Aspergillus nidulans	23.70	3.00e-08	52.80
IUUC-Ang-009875	Aspergillus niger	26.32	2.00e-05	43.50
IUUC-Ame-011668	Astyanax mexicanus	59.02	1.00e-85	310.00
IUUC-Bta-013219	Bos taurus	74.90	0.00e+00	967.00
IUUC-Bci-014000	Botrytis cinerea	23.29	5.00e-07	48.90
IUUC-Bdi-014527	Brachypodium distachyon	38.03	2.00e-09	56.20
IUUC-Bol-016438	Brassica oleracea	32.26	1.00e-08	54.30
IUUC-Bra-017526	Brassica rapa	32.26	1.00e-08	54.30
IUUC-Cel-018281	Caenorhabditis elegans	31.74	2.00e-15	77.40
IUUC-Cja-018759	Callithrix jacchus	80.08	0.00e+00	1099.00
IUUC-Cfa-020766	Canis familiaris	76.78	0.00e+00	994.00
IUUC-Cpo-022250	Cavia porcellus	79.68	0.00e+00	995.00
IUUC-Csa-023293	Chlorocebus sabaeus	81.11	0.00e+00	1120.00
IUUC-Cin-025556	Ciona intestinalis	38.87	4.00e-48	186.00
IUUC-Csv-026153	Ciona savignyi	40.00	5.00e-39	154.00
IUUC-Cgl-026733	Colletotrichum gloeosporioides	27.08	8.00e-04	38.10
IUUC-Cne-026936	Cryptococcus neoformans	26.47	3.00e-05	43.10
IUUC-Dre-027828	Danio rerio	44.07	4.00e-77	282.00
IUUC-Dse-031436	Dothistroma septosporum	30.95	1.00e-04	41.20
IUUC-Dme-031809	Drosophila melanogaster	32.89	2.00e-40	160.00
IUUC-Ete-032677	Echinops telfairi	87.54	2.00e-147	515.00
IUUC-Eca-034045	Equus caballus	75.77	3.00e-113	402.00
IUUC-Eeu-035063	Erinaceus europaeus	84.13	4.00e-163	568.00
IUUC-Fca-036488	Felis catus	79.44	0.00e+00	1027.00
IUUC-Fal-037501	Ficedula albicollis	55.62	0.00e+00	633.00
IUUC-Fso-038123	Fusarium solani	31.33	2.00e-04	40.00
IUUC-Gmo-038614	Gadus morhua	68.78	2.00e-76	280.00
IUUC-Ggr-039793	Gaeumannomyces graminis	36.25	3.00e-08	52.80
IUUC-Gga-040738	Gallus gallus	56.19	0.00e+00	701.00
IUUC-Gac-041381	Gasterosteus aculeatus	53.47	1.00e-97	350.00
IUUC-Gma-042964	Glycine max	30.88	3.00e-04	38.90
IUUC-Ggo-045139	Gorilla gorilla	80.98	0.00e+00	1113.00
IUUC-Hsa-046083	Homo sapiens	80.98	0.00e+00	1120.00
IUUC-Itr-048970	Ictidomys tridecemlineatus	81.70	0.00e+00	1030.00
IUUC-Kpa-049376	Komagataella pastoris	38.10	1.00e-05	43.50
IUUC-Lch-050369	Latimeria chalumnae	65.06	9.00e-68	251.00
IUUC-Lpe-050727	Leersia perrieri	32.86	8.00e-07	47.80
IUUC-Loc-052347	Lepisosteus oculatus	57.19	1.00e-72	267.00
IUUC-Lma-053027	Leptosphaeria maculans	22.32	3.50e-01	28.90
IUUC-Laf-053575	Loxodonta africana	82.16	0.00e+00	1100.00
IUUC-Mcc-054823	Macaca mulatta	80.03	0.00e+00	1063.00
IUUC-Meu-056878	Macropus eugenii	40.03	1.00e-96	346.00
IUUC-Mor-056948	Magnaporthe oryzae	31.87	5.00e-07	48.90
IUUC-Mtr-057811	Medicago truncatula	25.49	8.00e-04	37.40
IUUC-Mla-058917	Melampsora laricipopulina	36.62	6.00e-11	62.00
IUUC-Mga-059445	Meleagris gallopavo	56.62	0.00e+00	669.00
IUUC-Mmr-060665	Microcebus murinus	78.77	0.00e+00	1059.00
IUUC-Mdo-062430	Monodelphis domestica	63.57	0.00e+00	767.00
IUUC-Mac-065364	Musa acuminata	33.80	1.00e-04	39.70
IUUC-Mpu-066344	Mustela putorius furo	77.58	0.00e+00	992.00
IUUC-Mlu-068101	Myotis lucifugus	80.64	0.00e+00	1078.00
IUUC-Nfi-068489	Neosartorya fischeri	27.59	2.00e-07	50.40
IUUC-Opr-070498	Ochotona princeps	47.49	1.00e-45	177.00
IUUC-Ont-071579	Oreochromis niloticus	53.69	1.00e-87	317.00
IUUC-Oan-072862	Ornithorhynchus anatinus	56.60	0.00e+00	681.00
IUUC-Ocu-073882	Oryctolagus cuniculus	73.04	0.00e+00	831.00
IUUC-Oba-075710	Oryza barthii	35.21	2.00e-07	49.70
IUUC-Ogl-077171	Oryza glaberrima	35.21	2.00e-07	49.30
IUUC-Ogu-078827	Oryza glumaepatula	35.21	4.00e-07	49.30
IUUC-Oin-080204	Oryza indica	35.21	2.00e-07	49.70
IUUC-Olo-081049	Oryza longistaminata	35.21	2.00e-07	49.70
IUUC-Ome-081128	Oryza meridionalis	33.77	1.00e-05	42.70
IUUC-Oni-083077	Oryza nivara	35.21	1.00e-07	50.40
IUUC-Opu-083270	Oryza punctata	33.80	1.00e-06	47.00
IUUC-Oru-084299	Oryza rufipogon	33.77	1.00e-05	42.70
IUUC-Osa-085671	Oryza sativa	33.77	1.00e-06	44.70
IUUC-Ola-086456	Oryzias latipes	61.89	9.00e-92	331.00
IUUC-Oga-087918	Otolemur garnettii	81.48	0.00e+00	1074.00
IUUC-Oar-089663	Ovis aries	75.77	0.00e+00	966.00
IUUC-Ptr-091033	Pan troglodytes	80.19	0.00e+00	1077.00
IUUC-Pan-092277	Papio anubis	80.33	0.00e+00	1119.00
IUUC-Psi-094086	Pelodiscus sinensis	55.38	0.00e+00	687.00
IUUC-Pma-094683	Petromyzon marinus	45.82	1.00e-59	223.00
IUUC-Pno-094930	Phaeosphaeria nodorum	34.38	2.00e-09	56.60
IUUC-Pfo-097334	Poecilia formosa	59.09	4.00e-87	315.00
IUUC-Pab-098345	Pongo abelii	80.87	0.00e+00	1078.00
IUUC-Pop-099683	Populus trichocarpa	31.43	4.00e-04	36.60
IUUC-Pca-100737	Procavia capensis	79.23	0.00e+00	1066.00
IUUC-Pva-102497	Pteropus vampyrus	81.03	0.00e+00	1130.00
IUUC-Pgr-103464	Puccinia graminis	36.62	2.00e-11	61.60
IUUC-Pte-104288	Pyrenophora teres	29.79	3.00e-07	49.30
IUUC-Pyt-104772	Pyrenophora triticirepentis	28.72	6.00e-07	48.10
IUUC-Rno-105177	Rattus norvegicus	92.76	0.00e+00	1196.00
IUUC-Sce-106376	Saccharomyces cerevisiae	31.71	4.00e-07	48.90
IUUC-Sha-106480	Sarcophilus harrisii	66.58	0.00e+00	822.00
IUUC-Sja-107782	Schizosaccharomyces japonicus	27.41	1.00e-12	67.00
IUUC-Spo-108157	Schizosaccharomyces pombe	29.17	8.00e-11	60.10
IUUC-Sit-109960	Setaria italica	25.84	3.00e-04	38.90
IUUC-Sar-113255	Sorex araneus	68.74	0.00e+00	755.00
IUUC-Sbi-114855	Sorghum bicolor	38.03	3.00e-06	45.80
IUUC-Sre-115076	Sporisorium reilianum	37.00	7.00e-17	82.40
IUUC-Ssc-115875	Sus scrofa	79.67	0.00e+00	1070.00
IUUC-Tgu-117066	Taeniopygia guttata	52.49	3.00e-173	602.00
IUUC-Tru-117881	Takifugu rubripes	56.17	9.00e-93	334.00
IUUC-Tsy-119531	Tarsius syrichta	76.45	0.00e+00	1018.00
IUUC-Tni-120325	Tetraodon nigroviridis	39.81	6.00e-118	418.00
IUUC-Tae-122727	Triticum aestivum	30.77	2.00e-09	56.60
IUUC-Tur-126506	Triticum urartu	31.62	4.00e-08	51.60
IUUC-Tbe-127648	Tupaia belangeri	74.83	0.00e+00	947.00
IUUC-Ttr-129287	Tursiops truncatus	78.23	0.00e+00	1026.00
IUUC-Uma-129543	Ustilago maydis	33.64	3.00e-14	73.90
IUUC-Vpa-130645	Vicugna pacos	76.01	0.00e+00	986.00
IUUC-Xtr-132709	Xenopus tropicalis	57.05	2.00e-125	442.00
IUUC-Xma-133858	Xiphophorus maculatus	60.53	3.00e-88	319.00
IUUC-Yli-134386	Yarrowia lipolytica	32.14	5.00e-09	55.10
IUUC-Zma-135412	Zea mays	29.47	4.00e-06	45.10

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence