iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088992

Ensembl Protein ID

ENSOGAP00000007311.2

UniProt Accession

H0WXV6; H0WXV6_OTOGA

Genbank Protein ID

ENSOGAP00000007311

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03108890

Gene Name

RABGEF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000008166.2	ENSOGAT00000008173.2	ENSOGAP00000007311.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/ZnF_A20	3.80e-18	65.1	151	185

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/ZnF_A20

   S: 1    dpskllCkkgCgfYGnpetngyCSkCyreelrrrr 35
           d+s+llCkkgCg+YGnp+++g+CSkC+ree++++r
   Q: 151  DQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKAR 185
           79*******************************86 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MVVVTGRELD SRRPDGAMSS SDAEDDFLEP ATPTATQAGH ALPLMPQERR TEFPAFRGPA 60
SLGASAGCVQ RGPVLCHWTP PGTAGEHAAA EGREGAPGVS GTHALLQRPF GADCGDRPAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGGTAG TCACGGGGCG GGAGCTAGAC AGCCGTCGCC CGGACGGTGC CATGTCCAGC 60
TCCGACGCCG AAGACGACTT TCTGGAGCCG GCCACTCCGA CGGCCACGCA GGCAGGGCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003123--VPS9
IPR002653--Znf_A20

PROSITE

PS51205--VPS9
PS51036--ZF_A20

Pfam

PF02204--VPS9
PF01754--zf-A20

SMART

SM00167--VPS9
SM00259--ZnF_A20

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005730--C:nucleolus
GO:0003677--F:DNA binding
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0050728--P:negative regulation of inflammatory response
GO:1900165--P:negative regulation of interleukin-6 secretion
GO:1900235--P:negative regulation of Kit signaling pathway
GO:0002686--P:negative regulation of leukocyte migration
GO:0043305--P:negative regulation of mast cell degranulation
GO:0001933--P:negative regulation of protein phosphorylation
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0048261--P:negative regulation of receptor-mediated endocytosis
GO:0006612--P:protein targeting to membrane
GO:0060368--P:regulation of Fc receptor mediated stimulatory signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000198	Aegilops tauschii	31.96	6.00e-21	95.50
IUUC-Aml-001771	Ailuropoda melanoleuca	84.76	0.00e+00	1102.00
IUUC-Atr-003154	Amborella trichopoda	36.52	7.00e-23	101.00
IUUC-Apl-004018	Anas platyrhynchos	80.14	0.00e+00	830.00
IUUC-Aca-005227	Anolis carolinensis	24.43	7.00e-09	56.20
IUUC-Aly-006138	Arabidopsis lyrata	35.45	5.00e-25	108.00
IUUC-Ath-006747	Arabidopsis thaliana	34.92	1.00e-24	107.00
IUUC-Ago-007776	Ashbya gossypii	31.58	2.00e-22	100.00
IUUC-Acl-008235	Aspergillus clavatus	37.99	4.00e-27	116.00
IUUC-Afl-008570	Aspergillus flavus	39.38	8.00e-30	125.00
IUUC-Afu-008815	Aspergillus fumigatus	37.31	2.00e-27	117.00
IUUC-Ani-009381	Aspergillus nidulans	37.50	9.00e-28	118.00
IUUC-Ang-009615	Aspergillus niger	33.64	2.00e-29	123.00
IUUC-Aor-010195	Aspergillus oryzae	39.38	5.00e-30	125.00
IUUC-Ate-010514	Aspergillus terreus	38.74	1.00e-28	121.00
IUUC-Ame-011365	Astyanax mexicanus	63.93	8.00e-156	543.00
IUUC-Bgr-012102	Blumeria graminis	32.54	2.00e-27	117.00
IUUC-Bta-013124	Bos taurus	89.34	0.00e+00	760.00
IUUC-Bci-013943	Botrytis cinerea	34.13	4.00e-28	119.00
IUUC-Bdi-014539	Brachypodium distachyon	37.78	2.00e-26	113.00
IUUC-Bol-016580	Brassica oleracea	37.57	2.00e-29	123.00
IUUC-Bra-017843	Brassica rapa	37.04	5.00e-29	122.00
IUUC-Cel-018199	Caenorhabditis elegans	43.69	3.00e-47	182.00
IUUC-Cja-019941	Callithrix jacchus	89.10	0.00e+00	758.00
IUUC-Cfa-020845	Canis familiaris	89.57	0.00e+00	764.00
IUUC-Cpo-022037	Cavia porcellus	88.15	0.00e+00	747.00
IUUC-Cre-022696	Chlamydomonas reinhardtii	34.09	5.00e-21	95.90
IUUC-Csa-023495	Chlorocebus sabaeus	88.86	0.00e+00	761.00
IUUC-Cho-025076	Choloepus hoffmanni	86.24	7.00e-179	620.00
IUUC-Cin-025400	Ciona intestinalis	39.51	3.00e-108	385.00
IUUC-Csv-025941	Ciona savignyi	35.32	4.00e-80	292.00
IUUC-Cgl-026725	Colletotrichum gloeosporioides	31.73	5.00e-26	112.00
IUUC-Cne-027057	Cryptococcus neoformans	29.97	1.00e-31	131.00
IUUC-Dre-028484	Danio rerio	61.00	0.00e+00	637.00
IUUC-Dno-028906	Dasypus novemcinctus	89.23	0.00e+00	753.00
IUUC-Dor-030124	Dipodomys ordii	95.56	3.00e-143	501.00
IUUC-Dse-031437	Dothistroma septosporum	26.28	1.00e-24	108.00
IUUC-Dme-031696	Drosophila melanogaster	29.50	7.00e-64	238.00
IUUC-Ete-032573	Echinops telfairi	84.91	0.00e+00	705.00
IUUC-Eca-033711	Equus caballus	90.07	0.00e+00	763.00
IUUC-Eeu-034459	Erinaceus europaeus	73.43	5.00e-78	285.00
IUUC-Fca-035447	Felis catus	89.06	0.00e+00	765.00
IUUC-Fal-036605	Ficedula albicollis	77.44	0.00e+00	774.00
IUUC-Fox-037967	Fusarium oxysporum	28.57	3.00e-17	84.00
IUUC-Fso-038110	Fusarium solani	32.54	1.00e-27	118.00
IUUC-Gmo-038785	Gadus morhua	58.32	0.00e+00	639.00
IUUC-Ggr-039760	Gaeumannomyces graminis	39.35	1.00e-27	118.00
IUUC-Gga-040584	Gallus gallus	80.99	0.00e+00	843.00
IUUC-Gac-042469	Gasterosteus aculeatus	56.20	2.00e-158	551.00
IUUC-Gma-044237	Glycine max	37.43	3.00e-26	113.00
IUUC-Ggo-044498	Gorilla gorilla	74.29	5.00e-178	617.00
IUUC-Hsa-046625	Homo sapiens	89.34	0.00e+00	760.00
IUUC-Hvu-047155	Hordeum vulgare	37.78	8.00e-27	114.00
IUUC-Itr-048753	Ictidomys tridecemlineatus	88.63	0.00e+00	752.00
IUUC-Kpa-049160	Komagataella pastoris	27.44	6.00e-23	102.00
IUUC-Lch-050529	Latimeria chalumnae	76.31	0.00e+00	872.00
IUUC-Lpe-051024	Leersia perrieri	34.39	7.00e-29	121.00
IUUC-Loc-052644	Lepisosteus oculatus	67.15	4.00e-158	551.00
IUUC-Lma-053102	Leptosphaeria maculans	36.00	6.00e-26	112.00
IUUC-Laf-054337	Loxodonta africana	82.75	0.00e+00	853.00
IUUC-Mcc-055659	Macaca mulatta	84.64	2.00e-140	491.00
IUUC-Meu-056084	Macropus eugenii	77.38	2.00e-95	342.00
IUUC-Mor-057255	Magnaporthe oryzae	37.42	2.00e-25	111.00
IUUC-Mpo-057454	Magnaporthe poae	33.99	3.00e-28	119.00
IUUC-Mtr-058098	Medicago truncatula	36.65	4.00e-29	122.00
IUUC-Mla-059068	Melampsora laricipopulina	35.87	2.00e-30	126.00
IUUC-Mga-059624	Meleagris gallopavo	75.72	0.00e+00	907.00
IUUC-Mvi-060282	Microbotryum violaceum	30.36	4.00e-23	103.00
IUUC-Mmr-061142	Microcebus murinus	84.91	0.00e+00	880.00
IUUC-Mdo-062289	Monodelphis domestica	85.71	0.00e+00	774.00
IUUC-Mmu-063961	Mus musculus	88.15	0.00e+00	749.00
IUUC-Mac-065188	Musa acuminata	36.31	1.00e-22	100.00
IUUC-Mpu-066291	Mustela putorius furo	88.86	0.00e+00	763.00
IUUC-Mlu-067431	Myotis lucifugus	80.10	0.00e+00	837.00
IUUC-Nfi-068422	Neosartorya fischeri	37.89	1.00e-28	121.00
IUUC-Ncr-068843	Neurospora crassa	31.98	5.00e-28	119.00
IUUC-Nle-069079	Nomascus leucogenys	89.10	0.00e+00	757.00
IUUC-Opr-070790	Ochotona princeps	97.22	3.00e-58	219.00
IUUC-Ont-071789	Oreochromis niloticus	60.11	3.00e-169	587.00
IUUC-Oan-072946	Ornithorhynchus anatinus	83.04	0.00e+00	701.00
IUUC-Ocu-073816	Oryctolagus cuniculus	90.05	0.00e+00	767.00
IUUC-Oba-075738	Oryza barthii	33.15	1.00e-17	84.30
IUUC-Obr-076355	Oryza brachyantha	37.91	1.00e-27	117.00
IUUC-Ogl-077592	Oryza glaberrima	34.39	4.00e-27	115.00
IUUC-Ogu-078197	Oryza glumaepatula	33.50	7.00e-27	114.00
IUUC-Oin-080047	Oryza indica	37.64	9.00e-26	111.00
IUUC-Olo-080317	Oryza longistaminata	34.39	1.00e-26	114.00
IUUC-Ome-081589	Oryza meridionalis	37.22	2.00e-26	114.00
IUUC-Oni-082700	Oryza nivara	33.15	1.00e-17	84.70
IUUC-Opu-083923	Oryza punctata	34.36	1.00e-21	97.10
IUUC-Oru-084318	Oryza rufipogon	33.15	1.00e-17	84.70
IUUC-Osa-086246	Oryza sativa	38.98	5.00e-07	45.40
IUUC-Ola-086730	Oryzias latipes	54.68	2.00e-151	528.00
IUUC-Olu-087719	Ostreococcus lucimarinus	34.46	1.00e-23	104.00
IUUC-Oar-089789	Ovis aries	89.60	0.00e+00	764.00
IUUC-Ptr-091636	Pan troglodytes	89.34	0.00e+00	758.00
IUUC-Pan-092911	Papio anubis	88.63	0.00e+00	755.00
IUUC-Psi-093194	Pelodiscus sinensis	81.12	0.00e+00	905.00
IUUC-Pma-094212	Petromyzon marinus	43.08	3.00e-108	385.00
IUUC-Pno-094831	Phaeosphaeria nodorum	33.33	2.00e-26	114.00
IUUC-Ppa-095705	Physcomitrella patens	33.33	4.00e-30	125.00
IUUC-Pfo-096694	Poecilia formosa	56.78	2.00e-167	582.00
IUUC-Pab-097706	Pongo abelii	89.10	0.00e+00	758.00
IUUC-Pop-099891	Populus trichocarpa	37.43	1.00e-25	111.00
IUUC-Pca-100879	Procavia capensis	80.80	7.00e-93	333.00
IUUC-Ppe-101334	Prunus persica	35.98	4.00e-26	112.00
IUUC-Pva-103225	Pteropus vampyrus	80.38	7.00e-169	587.00
IUUC-Pgr-103564	Puccinia graminis	34.41	1.00e-29	125.00
IUUC-Ptt-103802	Puccinia triticina	46.02	7.00e-25	108.00
IUUC-Pte-104345	Pyrenophora teres	34.16	5.00e-26	113.00
IUUC-Pyt-104716	Pyrenophora triticirepentis	34.30	8.00e-27	115.00
IUUC-Rno-106101	Rattus norvegicus	87.91	0.00e+00	751.00
IUUC-Sce-106460	Saccharomyces cerevisiae	33.84	2.00e-23	103.00
IUUC-Sha-106919	Sarcophilus harrisii	78.33	0.00e+00	937.00
IUUC-Sja-107880	Schizosaccharomyces japonicus	37.50	3.00e-29	123.00
IUUC-Spo-108087	Schizosaccharomyces pombe	32.81	3.00e-26	112.00
IUUC-Ssl-108614	Sclerotinia sclerotiorum	29.82	1.00e-07	52.00
IUUC-Smo-109411	Selaginella moellendorffii	37.22	5.00e-29	122.00
IUUC-Sit-110678	Setaria italica	37.22	9.00e-27	114.00
IUUC-Sly-111526	Solanum lycopersicum	37.85	7.00e-26	111.00
IUUC-Stu-112494	Solanum tuberosum	36.93	2.00e-26	113.00
IUUC-Sar-112929	Sorex araneus	98.55	3.00e-163	568.00
IUUC-Sbi-114242	Sorghum bicolor	36.13	2.00e-27	117.00
IUUC-Sre-115224	Sporisorium reilianum	36.13	1.00e-28	122.00
IUUC-Ssc-115239	Sus scrofa	89.57	0.00e+00	766.00
IUUC-Tgu-117499	Taeniopygia guttata	78.70	0.00e+00	810.00
IUUC-Tru-118027	Takifugu rubripes	56.78	5.00e-163	567.00
IUUC-Tsy-119462	Tarsius syrichta	84.45	0.00e+00	849.00
IUUC-Tni-120855	Tetraodon nigroviridis	53.29	2.00e-164	572.00
IUUC-Tca-121213	Theobroma cacao	35.45	4.00e-25	108.00
IUUC-Tre-122186	Trichoderma reesei	31.62	1.00e-27	117.00
IUUC-Tvi-122541	Trichoderma virens	38.73	2.00e-27	117.00
IUUC-Tae-122942	Triticum aestivum	38.89	4.00e-27	115.00
IUUC-Tur-126572	Triticum urartu	38.89	6.00e-27	115.00
IUUC-Tme-127023	Tuber melanosporum	37.91	9.00e-30	125.00
IUUC-Tbe-127453	Tupaia belangeri	90.05	0.00e+00	764.00
IUUC-Ttr-128526	Tursiops truncatus	89.10	0.00e+00	758.00
IUUC-Uma-129660	Ustilago maydis	36.51	1.00e-28	122.00
IUUC-Vda-129737	Verticillium dahliae	30.59	4.00e-23	103.00
IUUC-Vpa-130505	Vicugna pacos	83.41	0.00e+00	694.00
IUUC-Vvi-131088	Vitis vinifera	37.08	3.00e-24	106.00
IUUC-Xtr-132799	Xenopus tropicalis	69.39	0.00e+00	721.00
IUUC-Xma-133345	Xiphophorus maculatus	57.34	4.00e-163	567.00
IUUC-Yli-134416	Yarrowia lipolytica	29.41	8.00e-30	125.00
IUUC-Zma-134750	Zea mays	37.78	2.00e-26	113.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence