iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022340

Ensembl Protein ID

ENSCPOP00000009555.2

UniProt Accession

H0VHC8; H0VHC8_CAVPO

Genbank Protein ID

ENSCPOP00000009555

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02017934

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000010644.3	ENSCPOT00000010741.2	ENSCPOP00000009555.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-22	79.7	243	289

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 243  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 289
           8********988.6*******************.*******7.******5 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

DWQPPFACDV DKLHFTPRIQ RLNELEAQTR VKLNFLDQIA KYWELQGSTL KIPHVERKIL 60
DLFQLNKLVA EEGGFAVVCK DRKWTKIATK MGFAPGKAVG SHIRGHYERI LNPYNLFLSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACTGGCAGC CACCATTTGC ATGTGATGTT GATAAACTTC ATTTTACCCC ACGTATCCAG 60
AGGCTGAACG AATTGGAGGT AATGTCCTCA CTAGTGTTTC AATGTCTATT CAGGAGGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	32.23	8.00e-102	365.00
IUUC-Aml-001963	Ailuropoda melanoleuca	95.60	0.00e+00	2766.00
IUUC-Atr-002595	Amborella trichopoda	32.92	5.00e-108	386.00
IUUC-Apl-003770	Anas platyrhynchos	85.63	0.00e+00	2164.00
IUUC-Aca-004867	Anolis carolinensis	81.59	0.00e+00	2410.00
IUUC-Ath-007218	Arabidopsis thaliana	35.56	4.00e-09	58.50
IUUC-Acl-008162	Aspergillus clavatus	31.39	2.00e-114	407.00
IUUC-Afl-008625	Aspergillus flavus	30.00	4.00e-109	390.00
IUUC-Afu-008796	Aspergillus fumigatus	30.29	3.00e-113	404.00
IUUC-Ani-009139	Aspergillus nidulans	35.52	2.00e-104	375.00
IUUC-Aor-010155	Aspergillus oryzae	30.00	4.00e-109	390.00
IUUC-Ate-010453	Aspergillus terreus	29.00	5.00e-107	383.00
IUUC-Ame-010620	Astyanax mexicanus	62.06	0.00e+00	1836.00
IUUC-Bgr-012241	Blumeria graminis	32.87	4.00e-100	360.00
IUUC-Bta-012733	Bos taurus	90.99	0.00e+00	2644.00
IUUC-Bci-013992	Botrytis cinerea	33.84	9.00e-104	372.00
IUUC-Bdi-014050	Brachypodium distachyon	28.61	1.00e-105	379.00
IUUC-Bol-015336	Brassica oleracea	34.23	3.00e-14	75.90
IUUC-Cja-019050	Callithrix jacchus	95.66	0.00e+00	2805.00
IUUC-Cfa-021015	Canis familiaris	95.53	0.00e+00	2757.00
IUUC-Csa-023441	Chlorocebus sabaeus	96.41	0.00e+00	2769.00
IUUC-Cho-024823	Choloepus hoffmanni	97.74	0.00e+00	1625.00
IUUC-Cin-025321	Ciona intestinalis	43.00	0.00e+00	899.00
IUUC-Csv-026185	Ciona savignyi	43.26	0.00e+00	860.00
IUUC-Cgl-026613	Colletotrichum gloeosporioides	29.92	1.00e-107	385.00
IUUC-Cne-026851	Cryptococcus neoformans	28.83	9.00e-112	399.00
IUUC-Dre-027707	Danio rerio	60.70	0.00e+00	1766.00
IUUC-Dno-028978	Dasypus novemcinctus	95.67	0.00e+00	2751.00
IUUC-Dor-030854	Dipodomys ordii	85.65	0.00e+00	1912.00
IUUC-Dse-031479	Dothistroma septosporum	27.74	2.00e-96	347.00
IUUC-Dme-032021	Drosophila melanogaster	44.05	0.00e+00	1004.00
IUUC-Ete-032760	Echinops telfairi	89.61	0.00e+00	1825.00
IUUC-Eca-034370	Equus caballus	95.87	0.00e+00	2696.00
IUUC-Eeu-035012	Erinaceus europaeus	76.51	0.00e+00	1879.00
IUUC-Fca-035494	Felis catus	96.41	0.00e+00	2766.00
IUUC-Fal-037631	Ficedula albicollis	83.11	0.00e+00	2416.00
IUUC-Fox-037694	Fusarium oxysporum	31.16	5.00e-96	346.00
IUUC-Fso-038127	Fusarium solani	32.60	1.00e-99	358.00
IUUC-Gmo-039522	Gadus morhua	58.33	0.00e+00	1644.00
IUUC-Ggr-039929	Gaeumannomyces graminis	31.37	7.00e-101	362.00
IUUC-Gga-040802	Gallus gallus	83.21	0.00e+00	2358.00
IUUC-Gac-041563	Gasterosteus aculeatus	61.30	0.00e+00	1773.00
IUUC-Gma-042675	Glycine max	32.82	2.00e-102	368.00
IUUC-Ggo-044856	Gorilla gorilla	79.26	0.00e+00	2147.00
IUUC-Hsa-045888	Homo sapiens	94.11	0.00e+00	2778.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	8.00e-16	79.30
IUUC-Itr-048297	Ictidomys tridecemlineatus	96.75	0.00e+00	2754.00
IUUC-Kpa-049245	Komagataella pastoris	20.83	2.00e-25	112.00
IUUC-Lch-050483	Latimeria chalumnae	65.64	0.00e+00	1967.00
IUUC-Lpe-051537	Leersia perrieri	31.69	1.00e-91	332.00
IUUC-Loc-052550	Lepisosteus oculatus	70.39	0.00e+00	2028.00
IUUC-Laf-053761	Loxodonta africana	94.04	0.00e+00	2707.00
IUUC-Mcc-055505	Macaca mulatta	94.18	0.00e+00	2780.00
IUUC-Mor-057198	Magnaporthe oryzae	29.84	1.00e-112	401.00
IUUC-Mpo-057317	Magnaporthe poae	28.59	7.00e-106	379.00
IUUC-Mtr-058113	Medicago truncatula	28.57	8.00e-92	332.00
IUUC-Mga-059358	Meleagris gallopavo	82.41	0.00e+00	2422.00
IUUC-Mmr-060863	Microcebus murinus	96.28	0.00e+00	2764.00
IUUC-Mdo-061957	Monodelphis domestica	88.49	0.00e+00	2610.00
IUUC-Mmu-063944	Mus musculus	93.70	0.00e+00	2686.00
IUUC-Mac-065069	Musa acuminata	36.04	2.00e-08	56.20
IUUC-Mpu-066719	Mustela putorius furo	93.61	0.00e+00	2735.00
IUUC-Mlu-068086	Myotis lucifugus	87.47	0.00e+00	2548.00
IUUC-Nle-069256	Nomascus leucogenys	94.25	0.00e+00	2781.00
IUUC-Ont-071756	Oreochromis niloticus	61.75	0.00e+00	1812.00
IUUC-Oan-073568	Ornithorhynchus anatinus	89.19	0.00e+00	2596.00
IUUC-Ocu-073961	Oryctolagus cuniculus	92.75	0.00e+00	2687.00
IUUC-Oba-075388	Oryza barthii	35.86	5.00e-72	267.00
IUUC-Obr-076296	Oryza brachyantha	39.77	1.00e-88	322.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	1.00e-16	82.40
IUUC-Ogu-079040	Oryza glumaepatula	28.38	4.00e-73	270.00
IUUC-Oin-079273	Oryza indica	50.00	2.00e-13	68.20
IUUC-Olo-080668	Oryza longistaminata	38.83	4.00e-16	81.60
IUUC-Ome-081764	Oryza meridionalis	30.77	6.00e-90	326.00
IUUC-Oni-083012	Oryza nivara	29.07	3.00e-72	268.00
IUUC-Opu-083164	Oryza punctata	31.64	3.00e-88	321.00
IUUC-Oru-084630	Oryza rufipogon	29.07	3.00e-72	267.00
IUUC-Osa-085487	Oryza sativa	38.83	1.00e-16	82.40
IUUC-Ola-086448	Oryzias latipes	61.40	0.00e+00	1771.00
IUUC-Oga-088501	Otolemur garnettii	92.23	0.00e+00	2391.00
IUUC-Oar-090162	Ovis aries	90.72	0.00e+00	2640.00
IUUC-Ptr-090816	Pan troglodytes	94.18	0.00e+00	2786.00
IUUC-Pan-092764	Papio anubis	96.48	0.00e+00	2773.00
IUUC-Psi-093918	Pelodiscus sinensis	83.12	0.00e+00	2244.00
IUUC-Pma-094137	Petromyzon marinus	52.28	0.00e+00	1224.00
IUUC-Pno-094879	Phaeosphaeria nodorum	30.75	3.00e-112	400.00
IUUC-Ppa-095839	Physcomitrella patens	53.45	1.00e-15	80.10
IUUC-Pfo-096777	Poecilia formosa	62.25	0.00e+00	1805.00
IUUC-Pab-097854	Pongo abelii	93.46	0.00e+00	2117.00
IUUC-Pca-100241	Procavia capensis	90.59	0.00e+00	1788.00
IUUC-Ppe-101504	Prunus persica	31.37	9.00e-101	362.00
IUUC-Pva-103035	Pteropus vampyrus	84.89	0.00e+00	2208.00
IUUC-Pte-104195	Pyrenophora teres	29.76	2.00e-112	400.00
IUUC-Pyt-104566	Pyrenophora triticirepentis	30.28	1.00e-113	405.00
IUUC-Rno-105574	Rattus norvegicus	92.08	0.00e+00	2624.00
IUUC-Sce-106207	Saccharomyces cerevisiae	35.27	8.00e-74	271.00
IUUC-Sja-107970	Schizosaccharomyces japonicus	20.42	6.00e-35	143.00
IUUC-Spo-108283	Schizosaccharomyces pombe	20.64	2.00e-40	162.00
IUUC-Ssl-108489	Sclerotinia sclerotiorum	29.59	3.00e-110	394.00
IUUC-Sit-110534	Setaria italica	32.78	6.00e-101	363.00
IUUC-Sly-111298	Solanum lycopersicum	42.66	3.00e-103	370.00
IUUC-Sar-113477	Sorex araneus	90.30	0.00e+00	2417.00
IUUC-Ssc-116132	Sus scrofa	94.10	0.00e+00	2353.00
IUUC-Tgu-117452	Taeniopygia guttata	83.76	0.00e+00	2422.00
IUUC-Tru-117561	Takifugu rubripes	62.57	0.00e+00	1649.00
IUUC-Tsy-119271	Tarsius syrichta	93.76	0.00e+00	2160.00
IUUC-Tni-119650	Tetraodon nigroviridis	60.55	0.00e+00	1741.00
IUUC-Tca-121478	Theobroma cacao	42.57	9.00e-104	372.00
IUUC-Tre-122213	Trichoderma reesei	29.25	2.00e-103	370.00
IUUC-Tvi-122263	Trichoderma virens	33.61	6.00e-97	349.00
IUUC-Tae-125894	Triticum aestivum	32.15	7.00e-103	369.00
IUUC-Tur-126632	Triticum urartu	32.10	9.00e-101	362.00
IUUC-Tme-127087	Tuber melanosporum	29.30	9.00e-115	409.00
IUUC-Tbe-127890	Tupaia belangeri	90.19	0.00e+00	1545.00
IUUC-Ttr-128546	Tursiops truncatus	89.83	0.00e+00	1937.00
IUUC-Vda-129733	Verticillium dahliae	28.43	9.00e-99	355.00
IUUC-Vpa-130432	Vicugna pacos	88.71	0.00e+00	1562.00
IUUC-Vvi-131071	Vitis vinifera	30.89	9.00e-84	305.00
IUUC-Xtr-132008	Xenopus tropicalis	70.81	0.00e+00	2070.00
IUUC-Xma-133571	Xiphophorus maculatus	61.84	0.00e+00	1782.00
IUUC-Zma-135829	Zea mays	32.96	9.00e-100	359.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence